Claim Missing Document
Check
Articles

Found 20 Documents
Search

Changes in The Aging Cytoskeleton and How Metformin Plays a Role in Delaying Aging Dini, Dini; Achadiyani, Achadiyani; Khairani, Astrid Feinisa
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 9, No 1 (2024): March 2024
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/jika.v9i1.2672

Abstract

The cytoskeleton plays an important role in forming the cell framework and dynamics. The part that plays a role in supporting the spatial and mechanical functions of the cell is located in the cytoskeleton. Therefore, strategies to maintain the integrity and dynamics of the cytoskeleton have potential as therapies for age-related disorders. One thing that can be used to delay aging is metformin. Through AMPK activation, it can influence the cytoskeleton; namely, it can remodel the dynamics of the cytoskeleton by influencing structural changes in the actin cytoskeleton, which in turn will reduce the permeability of the filtration barrier in diabetic conditions and can increase insulin sensitivity, especially in old age, thereby delaying aging. In this review, we review the current understanding of the role played by the cytoskeleton in aging and review the opportunities and challenges for transitioning basic research into intervention development. Methods: Several major electronic databases, including PubMed, Scopus, and Cohcrane were used to select articles between April 2013 and April 2023. From the 8 existing literature, we present the activity of metformin as an aging delay. Cytoskeleton can change with age so it can affect the dynamics and structure of the cell. Metformin shows significant benefits, especially in delaying aging, through activation of the AMPK pathway so that it can increase the activity of mitochondria in producing ATP, which can affect the structure of the cytoskeleton. With this article on changes in the cytoskeleton with aging, it is hoped that insight into future research directions can be achieved.
Analisis Pengetahuan Investasi Pada Mahasiswa STIE Pembangunan Tanjungpinang Dalam Mengantisipasi Resiko Investasi Dini, Dini; Salihi, Salihi; Yusrizal, Yusrizal; Sambodo, Bambang
ULIL ALBAB : Jurnal Ilmiah Multidisiplin Vol. 3 No. 9: Agustus 2024
Publisher : CV. Ulil Albab Corp

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56799/jim.v3i9.4919

Abstract

Tujuan dari penelitian ini adalah untuk untuk mengetahui apakah pengetahuan investasi berperan penting dalam mengantisipasi resiko investasi. Penelitian ini menggunakan data primer. Metode yang digunakan dalam penelitian ini adalah penelitian kualitatif, penggunaan metode kualitatif. Teknik pengumpulan data dalam penelitian ini adalah menggunakan kuesioner, dokumentasi, dan penelitian kepustakaan. Dimana 100 responden mengisi kuesioner yang berisikan 30 pernyataan yang berkaitan dengan variabel penelitian. Teknik analisis data yang digunakan adalah pengumpulan data, reduksi data, penyajian data dan penarikan kesimpulan. Hasil penelitian ini menunjukkan bahwa mayoritas mahasiswa STIE Pembangunan Tanjungpinang belum cukup memahami pengetahuan tentang berinvestasi, namun mayoritas mahasiswa STIE telah berinvestasi, dapat disimpulkan bahwa mahasiswa STIE Pembangunan Tanjungpinang tidak memiliki pengetahuan yang mumpuni terlebih dahulu sebelum mereka berinvestasi, sehingga gampang tergiur keuntungan yang besar tanpa mempertimbangkan resiko berinvestasi. Penting bagi mahasiswa STIE Pembangunan Tanjungpinang untuk memperdalam pengetahuan mereka tentang investasi yang akan mereka ambil dengan melihat resiko nya, tempat berinvestasi apakah tempat yang resmi dan legal, serta mengetahui kelebihan dan kekurangan jenis investasi yang akan mereka ambil.
Upaya Peningkatan Mutu Pendidikan Anak-Anak Melalui Program Huma Harati Di Desa Pahawan KRISTHY, Mutia Evi; JIMILYN, Jimilyn; PUTRI, Melani; WAOMA, Roslina; MANAL, Paska Anastasya; NURYAQIN, Nanda Allifa; BAYU, Bayu; YAHYA, Jaini; E, Agnes; ARIEFTA, Safira Nurillia; AMELIA, Amelia; KIRANA, Kirana; LASE, Yamonaha; TAMBA, Lastriko; SAPUTRA, Aldi; DINI, Dini
Akuntansi dan Humaniora: Jurnal Pengabdian Masyarakat Vol. 2 No. 2 (2023): Akuntansi dan Humaniora: Jurnal Pengabdian Masyarakat (Juni – September 2023)
Publisher : Indonesia Strategic Sustainability

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38142/ahjpm.v2i2.774

Abstract

KKN Tematik I Reguler (KKNT-I Reguler) merupakan suatu bentuk impelemtasi Kampus Merdeka. Melalui kegiatan KKNT-I Reguler ini, Universitas Palangka Raya (UPR) berusaha untuk meningkatkan kompetensi dan peran mahasiswa sebagai agen perubahan masyarakat, meningkatkan kepekaan sosial, menumbuhkan jiwa kerelawanan, kemampuan kolaborasi dan tanggung jawab terhadap masyarakat. Desa Pahawan, Kecamatan Banama Tingang, Kabupaten Pulang Pisau merupakan desa dengan mayoritas penduduk bekerja sebagai petani atau pekebun. Tema yang dilaksanakan oleh KKN pada tahun ini mengusung tema “Membangun Desa”. Desa Pahawan bisa disebut dengan desa maju, karena infrastruktur di desa ini hampir memadai. Namun, ada beberapa anak-anak desa Pahawan yang sudah menginjak SMP & SMA tapi masih belum lancar membaca, menulis, dan berhitung, maka dari itu kelompok 75 KKN-T Desa Pahawan ingin membuka bimbingan belajar gratis sebagai salah satu proker unggulan untuk membantu warga desa mengajar anak yang ingin belajar. Tujuan dari bimbigan belajar huma harati sangat berperan penting bagi perkembangan belajar anak-anak desa, karena tidak hanya apa yang diperoleh di sekolah saja, namun pembelajaran di huma harati juga memiliki dampak yang besar bagi pendidikan anak-anak desa dan memotivasi belajar anak-anak desa. Bimbingan belajar di huma harati ini tidak menggunakan metode pembelajaran yang formal, tetapi menggunakan metode pembelajaran belajar sambil bermain agar anak-anak desa tidak mudah bosan, sehingga membuat anak menjadi kreatif dan aktif dalam berfikir dan memecahkan masalah.
Analisis Kinerja Keuangan PT. Tera Data Indonusa Tbk Menggunakan Kecerdasan Buatan terhadap Profitabilitas pada Tahun 2022-2023 Amal, Bahar; Maharani, Hanifa Azzahra; Sholihaty, Bunga Sabrina; Fatimah, Ayu Yulia Candra; Dini, Dini; Maulida, Fatia Wahidatul; Rahayu, Desty Puspa
Jurnal Pendidikan Tambusai Vol. 8 No. 3 (2024)
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai, Riau, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Penelitian ini bertujuan untuk menganalisis kinerja keuangan PT Tera Data Indonusa Tbk. Selama periode 2022- 2023 menggunakan pendekatan manual dan berbasis kecerdasan buatan (Artificial Intelligence/AI). PT Tera Data Indonusa Tbk merupakan salah satu perusahaan terkemuka dalam industri teknologi informasi dan komunikasi di Indonesia, dengan fokus pada pengelolaan operasional dan penjualan grosir perangkat komputer. Analisis dilakukan untuk mengukur profitabilitas perusahaan menggunakan indikator Return on Assets (ROA), Return on Equity (ROE), dan Profit Margin. Hasil penelitian menunjukkan bahwa PT Tera Data Indonusa Tbk berhasil meningkatkan profitabilitasnya secara signifikan, ditandai dengan kenaikan Profit Margin dari 6,03% pada 2022 menjadi 9,99% pada 2023, ROA dari 8,24% menjadi 13,52%, dan ROE dari 18,09% menjadi 23,80%. Analisis berbasis AI memperkuat temuan ini dengan mengidentifikasi efisiensi operasional (35%) dan pertumbuhan pendapatan (30%) sebagai kontributor utama peningkatan profitabilitas Perusahaan. Kedua pendekatan analisis memberikan wawasan yang saling melengkapi. Analisis manual menyoroti peningkatan perhitungan keuangan, sementara AI menawarkan pemahaman lebih mendalam terkait faktor pendorong kinerja perusahaan. Penelitian ini juga merekomendasikan strategi peningkatan efisiensi operasional, diversifikasi produk, dan pengelolaan aset yang lebih optimal untuk mempertahankan pertumbuhan keuangan di masa depan.
ANALISIS PENERAPAN KEPEMIMPINAN TRANSFORMASIONAL PADA FORUM OSIS BANDUNG BARAT (FOBB) dini, dini; fizi
Jurnal Ekonomi Bisnis Manajemen Prima Vol. 6 No. 1 (2024): Jurnal Ekonomi Bisnis Manajemen Prima
Publisher : JEBIM Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jebim.v6i1.5022

Abstract

The West Bandung OSIS Forum (FOBB) is a special forum or organization for West Bandung Regency OSIS administrators. FOBB can be a strategic and important forum in efforts to hone leadership, character, competence and literacy among West Bandung Regency students. The successful implementation of this FOBB is certainly not far from the leadership style of the FOBB currently in office. Therefore, the aim of this research is to identify and analyze the transformational leadership that occurs at the West Bandung OSIS Forum. The analysis carried out is based on the characteristics of transformational leaders which consist of ideal influence or charisma, Inspirational Motivation, Intellectual Stimulation and individual attention. The type of research carried out was qualitative research with the determination of informants using purposive sampling and data collection techniques using observation and interviews. The research results show that the leader of the West Bandung OSIS Forum has implemented transformational leadership, and meets every characteristic of a transformational leader, however the transformational leadership that has been implemented still needs to be maximized so that the forum and members can continue to develop. Keywords: Character, Leadership, Transformational
AFIKS PEMBENTUK VERBA DALAM BAHASA BUGIS PADA KARANGAN BEBAS SISWA KELAS VII SMP MUHAMMADIYAH SOPPENG Dini, Dini; Syamsudduha, Syamsudduha; Hajrah, Hajrah
Journal Studies in Indonesian Language and Literature Vol. 1 No. 2 (2024): Journal Studies in Indonesian Language and Literature
Publisher : Journal Studies in Indonesian Language and Literature

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This research is a descriptive qualitative research which aims to describe the types and meanings of verb-forming affixes in Bugis language in students' free essays. Data and data sources in this research are written data in the form of words containing verb-forming affixes. The data collection technique used in this research is document analysis which is morphological study with note-taking technique. The analysis technique includes data reduction, data presentation and conclusion drawing. Based on the results of data analysis, the types and meanings of verb-forming affixes in students' free essays were found. (1) types of verb-forming affixes in Bugis language, namely prefix maG-, mappa-, mappasi-, infix -ul-, suffix -i-, confix pa-...-i. (2) The meaning of affixes forming verbs in Bugis language, namely prefix maG-, doing an action, mappa- making an activity. The meaning of the infix -ul- to do an action. The meaning of the suffix -i, states the command and means to cause as mentioned in the base word. The meaning of the confix pa-...-i, means to make something.
Improving Community Economic Value Through Utilization of Oil Palm Leaf Midribs into Export Handicraft Products Yuliza, Mai; Desda, Mia Muchia; Elondri, Elondri; Adriwilza, Adriwilza; Nurhamzah, Nurhamzah; Endarwita, Endarwita; Yurasti, Yurasti; Sari, Ria Widhia; Satriadi, Satriadi; Febianni, Valen; Dini, Dini
JOURNAL OF SUSTAINABLE COMMUNITY SERVICE Vol. 5 No. 1 (2024): DECEMBER
Publisher : Transpublika Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55047/jscs.v5i1.869

Abstract

This community service activity aims to increase the economic value of the community through the utilization of oil palm leaf midribs that have been underutilized into export-valued handicraft products. Palm oil is a leading commodity in many regions in Indonesia, but the waste in the form of leaf midribs is often neglected. Through training and mentoring programs, the community is able to produce a variety of innovative new designs, following modern market trends. palm oil leaf midribs handicrafts not only have functional value but also a more attractive aesthetic value. In addition, this activity also includes education on international marketing strategies and export market access. The results of the activities showed an increase in community knowledge and skills in processing oil palm leaf midribs and an increase in economic income through marketing products to international markets. This activity is expected to be sustainable and become a model for local resource-based economic development.
Penyuluhan Kesehatan Reproduksi dan Senam Dismenore: Strategi Partisipatif Meningkatkan Pengetahuan dan Kesehatan Remaja Putri Tampubolon, Masrina Munawarah; Siregar, Nabilah; Lestari, Widia; Chesy, Chesy; Dafri, Dafri; Dini, Dini; Putri, Putri; Siti, Siti; Fandra, Fandra; Fitri, Fitri; Hasniati, Hasniati; Irza, Irza; Monika, Monika; Nathania, Nathania; Septia, Septia; Septiana, Septiana
Jurnal Pengabdian Masyarakat (ABDIRA) Vol 6, No 2 (2026): Abdira
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdira.v6i2.1797

Abstract

Adolescent girls are a vulnerable group to reproductive health issues, particularly a lack of knowledge about menstrual care and dysmenorrhea, which can disrupt daily activities. This community service activity aims to improve adolescent girls' knowledge and skills in maintaining reproductive health and implementing non-pharmacological methods to reduce menstrual pain. The program involved 30 participants through participatory health education and demonstrations of dysmenorrhea exercises at MTs Bustanul Ulum, Pekanbaru City. Evaluation was conducted using pre- and post-tests. Results showed a significant increase in knowledge scores from 83.33 to 98.33, as well as improved ability to perform the exercises correctly. Most participants also reported reduced pain and greater relaxation. This activity effectively increased reproductive health literacy and introduced safe alternatives for managing menstrual pain.
Pengaruh Adversity Quotien Terhadap Kemampuan Pemecahan Masalah Matematis Dalam Menyelesaikan Soal Bertipe Hots Berdasarkan Langkah Polya Dini, Dini; Yani T, Ahmad; Ahmad, Dian; Mirza, Ade; Hartoyo, Agung
Educatio Vol 21 No 1 (2026): Educatio: Jurnal Ilmu Kependidikan
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/edc.v21i1.34371

Abstract

The influence of Adversity Quotient (AQ) on students' mathematical problem-solving in answering Higher Order Thinking Skills (HOTS) type questions based on Polya’s steps is highly essential. This research employed an ex-post facto method involving 60 eleventh-grade students of SMA Bawari Pontianak. Data were collected through the measurement of students’ Adversity Quotient levels and a mathematical problem-solving test designed in accordance with Polya’s four-step process: understanding the problem, devising a plan, carrying out the plan, and reviewing the solution. The analysis results indicated a highly significant effect of Adversity Quotient on students' mathematical problem-solving abilities. A significance value of 0.00 (< 0.05) and a Pearson correlation coefficient of 0.421 suggest a moderately strong positive relationship. Students with high to very high Adversity Quotient tended to solve HOTS-type problems more systematically and effectively compared to those with moderate or low AQ. They were also more capable of completing all four of Polya’s steps comprehensively. These findings highlight that mental resilience, perseverance, and the ability to manage pressure are critical factors in successfully solving high-level mathematical problems. Therefore, strengthening students’ Adversity Quotient through instructional strategies and non-cognitive support is strongly recommended to enhance their problem-solving quality.
Integrasi Media Digital dalam Pembelajaran PAI: Analisis Tantangan dan Peluang Dini, Dini; Nugraha, Mulyawan Safwandy
JIPENDIKA : Jurnal Inovasi Pembelajaran dan Pendidikan Vol. 2 No. 1 (2026): JIPENDIKA: Jurnal Inovasi Pembelajaran dan Pendidikan
Publisher : CV. Berkah Cakrawala Inspirasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66959/1mc7e533

Abstract

This study aims to analyze the role of Islamic Religious Education (PAI) teachers in instilling national values through the paradigm of religious moderation at SMA Azzainiyyah Nagrog, Sukabumi. Employing a qualitative case study approach, data were collected through in-depth interviews, observations, and document analysis. The findings reveal that PAI teachers act as agents of change through three primary dimensions: as designers of contextual learning integrating national values into religious materials, as facilitators of critical dialogue to cultivate moderate reasoning, and as living models demonstrating the alignment between faith and patriotism. The success of this role is supported by a school culture that harmonizes religious and national symbols, along with the collective commitment of the school community. However, challenges such as student background diversity, social media influence, an requires a systematic ecosystem of support, encompassing teacher competency enhancement, visionary school leadership, and parental partnership.