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All Journal Acta Biochimica Indonesiana Cendana Medical Journal Journal of Comprehensive Science JUKEJ: Jurnal Kesehatan Jompa
PAKAN, PRISCA DEVIANI
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Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Electrical & Electronics Engineering Health Professions Languange, Linguistic, Communication & Media Library & Information Science Medicine & Pharmacology Nursing Public Health Veterinary

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Activity Test of Anti-Dandruff Shampoo Preparation of Fragrant Pandan Leaf Extract (Pandanus Amaryllifolius Roxb.) Against the fungus Malassezia Furfur Pallo, Arini Aprili; Pakan, Prisca Deviani; Indriarini, Desi; Riwu, Magdarita
Journal of Comprehensive Science Vol. 5 No. 2 (2026): Journal of Comprehensive Science
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jcs.v5i2.4022

Abstract

Dandruff is a scalp disorder caused by Malassezia furfur fungus, often treated with anti-dandruff shampoos. However, synthetic active ingredients in such shampoos may cause side effects like scalp irritation, dryness, or allergies. As an alternative, herbal formulations using fragrant pandan leaves (Pandanus amaryllifolius Roxb.), known for their antifungal properties, can be developed. The objective of this study was to determine and analyze the best Fragrant pandan (Pandanus amaryllifolius Roxb.) leaf extract shampoo formulation and its antifungal activity against Malassezia furfur. The type of research conducted was a true experimental study with a Post-Test Only Control Group Design. In this study, there were treatment groups given a shampoo preparation of fragrant pandanus leaf extract at concentrations of 30%, 50%, and 70%, a negative control group of a shampoo base, and a positive control group of a shampoo containing 1% selenium sulfide under the brand name Selsun. The analysis used was the One-Way ANOVA test. The shampoo preparation of fragrant pandanus leaf extract demonstrated antifungal activity against Malassezia furfur, with inhibition zones obtained at a 30% concentration (15.83 mm), 50% concentration (18.68 mm), 70% concentration (21.89 mm), positive control (21.36 mm), and negative control (0 mm). The 70% Fragrant pandan (Pandanus amaryllifolius Roxb.) leaf extract shampoo preparation is the best formulation because it exhibits optimal physical characteristics and produces the greatest inhibition against Malassezia furfur.
Potensi Antibakteri Fermentat Nira Siwalan oleh Bacillus subtilis terhadap Staphylococcus aureus Abdullah, Fatih; Pakan, Prisca Deviani; Hutasoit, Regina Marvina; Amat, Anita Lidesna Shinta
JUKEJ : Jurnal Kesehatan Jompa Vol 5 No 1 (2026): JUKEJ: Jurnal Kesehatan Jompa
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jkj.Vol5.Iss1.2501

Abstract

Fermentasi Bacillus subtilis menggunakan nira siwalan (Borassus flabellifer L.) sebagai sumber karbon telah dilakukan untuk mengevaluasi aktivitas antibakterinya terhadap Staphylococcus aureus. Penelitian ini merupakan true experimental dengan rancangan post-test only control group design. Kelompok perlakuan diberi nira siwalan pada konsentrasi 10%, 20%, dan 30%, sedangkan kelompok kontrol negatif menggunakan aquadest steril. Aktivitas antibakteri diuji dengan metode difusi cakram, dan data dianalisis menggunakan uji One Way ANOVA diikuti uji Dunnett T3. Hasil penelitian menunjukkan bahwa produk fermentasi menghasilkan zona hambat dengan diameter berkisar 18,87–22,29 mm pada seluruh konsentrasi perlakuan, yang secara signifikan berbeda dari kontrol negatif (p = 0,000). Disimpulkan bahwa nira siwalan dapat dimanfaatkan sebagai media fermentasi Bacillus subtilis untuk menghasilkan senyawa antibakteri.
Uji Efektivitas Antibakteri Formula Sediaan Gel Facial Wash Ekstrak Daun Sukun (Artocarpus Altilis) terhadap Bakteri Staphylococcus Aureus Kerans, Elisabeth Dona Maria; Pakan, Prisca Deviani; Damanik, Efrisca M. Br.; Riwu, Magdarita
Journal of Comprehensive Science Vol. 5 No. 4 (2026): Journal of Comprehensive Science
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jcs.v5i4.4119

Abstract

Jerawat adalah masalah kulit umum yang disebabkan oleh bakteri seperti Propionibacterium acnes, Staphylococcus epidermidis, dan Staphylococcus aureus. Sabun cuci muka anti jerawat sering digunakan untuk mengatasinya, namun bahan aktif seperti benzoil peroksida bisa menyebabkan dermatitis kontak. Daun sukun (Artocarpus altilis) adalah salah satu tanaman yang berpotensi menjadi bahan alami dalam pembuatan sabun cuci muka anti-jerawat karena memiliki sifat antibakteri. Mengetahui dan menganalisis formula gel facial wash terbaik dari ekstrak daun sukun (Artocarpus altilis) dan efek antibakterinya pada bakteri Staphylococcus aureus. Jenis penelitian yang dilakukan True Experimental dengan rancangan Post- Test Only Control Group Design. Terdapat kelompok perlakuan yang diberi sediaan gel facial wash ekstrak daun sukun dengan konsentrasi 2,5%, 5%, 10%, kelompok kontrol negatif basis basis gel facial wash, dan kelompok kontrol positif facial wash berbahan benzoil peroksida dengan merk Panoxyl. Analisis yang digunakan adalah uji One Way Anova. Sediaan gel facial wash ekstrak daun sukun memiliki efektivitas antibakteri terhadap bakteri Staphylococcus aureus, dengan zona hambat yang didapatkan 2,5% (10,41 mm), konsentrasi 5% (12,78 mm), konsentrasi 10% (14,07 mm), kontrol positif (22,96 mm), dan kontrol negatif (0 mm). Formula konsentrasi 2,5% merupakan konsentrasi terbaik gel facial wash ekstrak daun sukun karena memiliki sifat fisik yang optimal dengan aroma ekstrak daun sukun yang tidak terlalu kuat sehingga lebih nyaman untuk digunakan serta memiliki efek antibakteri kategori kuat.
LITERATURE REVIEW PERBANDINGAN EFEKTIVITAS EKSTRAK TANAMAN KELOR (Moringa oleifera) DENGAN KETOKONAZOL DALAM MENGHAMBAT PERTUMBUHAN Candida sp. PADA Saboraud Dextrose Agar Sonbait, Lidya Lyke; Pakan, Prisca Deviani; Trisno, Idawati; Lada, Christina Olly
Cendana Medical Journal Vol 14 No 1 (2026): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v14i1.18538

Abstract

Background: One of the fungi that often causes infectious diseases is Candida albicans with a worldwide prevalence of 66%. Candidiasis as a disease caused by Candida albicans infection can be found throughout the world and is able to attack all ages, both men and women. Purpose: To compare the effectiveness of Moringa oleifera plant extract with ketoconazole in inhibiting Candida sp. on Saboraud Dextrose Agar. Methods: The method of searching for article data sources is carried out through the Google Scholar and PubMed databases (2015-2020) to retrieve relevant articles published in English and Indonesian. Key terms and phrases related to the comparative effectiveness of Moringa oleifera, ketoconazole, Candida sp. growth, Saboraud Dextrose Agar used in the subject search. Results: Based on the results of a literature review from 23 journals consisting of comparative characteristics of the effectiveness of Moringa oleifera and ketoconazole plant extracts, 11 journals found that ketoconazole Moringa oleifera plant extract was more effective than ketoconazole, while 12 other journals said that ketoconazole was more effective. By doing a comparison between the two methods, it was found that ketoconazole was more effective to be used in inhibiting the growth of Candida sp. than Moringa oleifera plant extract. Conclusion: Based on 23 journals conducted by a literature review, it can be concluded that ketoconazole has better effectiveness in inhibiting the growth of Candida sp. than Moringa oleifera plant extract.
Efektivitas Formula Sediaan Sampo Antijamur Ekstrak Kulit Pisang Kepok (Musa paradisiaca L.) Terhadap Pertumbuhan Malassezia furfur Seda Pia, Maria Vianey Dominika; Pakan, Prisca Deviani; Ningsih, Iswa; Indriarini, Desi
Cendana Medical Journal Vol 14 No 1 (2026): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v14i1.27362

Abstract

Abstract Background: Malassezia furfur is a pathogenic organism that causes dandruff. One way to prevent dandruff is by washing the hair using shampoo that contains anti-dandruff active ingredients. Continuous use of synthetic shampoos can cause the hair to become dry, easily brittle, irritate the eyes and scalp, and damage the hair shaft. Herbal shampoos have become popular due to consumers’ belief that they contain natural ingredients that are safer and have minimal side effects. One natural ingredient that can be used is the peel of kepok banana (Musa paradisiaca L.). Objective: To determine the antifungal activity of a shampoo formulation containing kepok banana peel extract (Musa paradisiaca L.) against the growth of Malassezia furfur. Methods: The type of research conducted was a true experimental study with a post-test only control group design. In this study, there were treatment groups given shampoo containing kepok banana peel extract at concentrations of 1.56%, 3.125%, 6.25%, 12.5%, 25%, 50%, and 100%, a negative control group using the shampoo base, and a positive control group using shampoo containing 1% selenium sulfide. The data were analyzed using One-Way ANOVA. Results: All shampoo formulations showed suboptimal physical characteristics. Concentrations of 6.25%, 12.5%, 25%, 50%, and 100% demonstrated antifungal activity against the growth of Malassezia furfur. Conclusion: There is antifungal activity from the shampoo formulation containing kepok banana peel extract (Musa paradisiaca L.) against the growth of Malassezia furfur.
Co-Authors Abdullah, Fatih Anita Lidesna Shinta Amat Artawan, I Made Christina Olly Lada Damanik, Efrisca M. Br Damanik, Efrisca M. Br. Deri Riskiyanti Tallo Manafe Dhenge, Neumensia Febrianti Djahi, Sri Nur Nur Saidah Dupe, Shita Anggenella E D, Maria Agnes Edon, Cindy Marie Agnes Lorenza Aurelia Flugentius, Bartolomeus Umbu Foni, Maria Laranita Meak Go, Dinsella Go, Stephannie Felicia Hutasoit, Regina M Hutasoit, Regina Marvina Idawati Trisno Ina Tuto, Yolanda Yasinta Indriarini, Desi Jumba, Cynthia Benedikta Kartikahadi, Anselma Dyah Kerans, Elisabeth Dona Maria Koamesah, Sangguana Marthen Jacobus Konay, Soeharty Megawaty Kresnawati Wahyu Setiono Lidia, Kartini Maromon, Yeyen ningsih, Iswa Nurina, Rr. Listyawati Pallo, Arini Aprili Pandie, Sinyo Demitrio Kurniawan Qurrota’ayun, Aisyah Rahmaningtyas, Dewinda Rambu Kareri, Dyah Gita Rante, Su Djie To Ratu Edo, Megaputri Yoriska Ratu, Kristian Riantoby, Raphaeline Murtiastari Rini, Desi Indria Riwu, Magdarita Sagita, Sidarta Seda Pia, Maria Vianey Dominika Septyowati, Mega Ayu Sequera, Maria Trisya Goncalves Seran, Dania Ekasanti M. Setianingrum, Elisabeth Levina Sari Setiawan, I Made Buddy Sonbait, Lidya Lyke Suki, Alce Apri Feranita Sumbayak, Anastasia Emma Reinaita Supardi, Fretrien Jiliamarch Syafira, Nadhifa Ainun Tandang, Fransiskus Tarigan, Gloria Josephin Thaal, Mario Bernardo Woda, Rahel Rara Wungouw, Herman Pieter L Zefania, Zefania