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All Journal Acta Biochimica Indonesiana Cendana Medical Journal Journal of Comprehensive Science JUKEJ: Jurnal Kesehatan Jompa
PAKAN, PRISCA DEVIANI
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Activity Test of Anti-Dandruff Shampoo Preparation of Fragrant Pandan Leaf Extract (Pandanus Amaryllifolius Roxb.) Against the fungus Malassezia Furfur Pallo, Arini Aprili; Pakan, Prisca Deviani; Indriarini, Desi; Riwu, Magdarita
Journal of Comprehensive Science Vol. 5 No. 2 (2026): Journal of Comprehensive Science
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jcs.v5i2.4022

Abstract

Dandruff is a scalp disorder caused by Malassezia furfur fungus, often treated with anti-dandruff shampoos. However, synthetic active ingredients in such shampoos may cause side effects like scalp irritation, dryness, or allergies. As an alternative, herbal formulations using fragrant pandan leaves (Pandanus amaryllifolius Roxb.), known for their antifungal properties, can be developed. The objective of this study was to determine and analyze the best Fragrant pandan (Pandanus amaryllifolius Roxb.) leaf extract shampoo formulation and its antifungal activity against Malassezia furfur. The type of research conducted was a true experimental study with a Post-Test Only Control Group Design. In this study, there were treatment groups given a shampoo preparation of fragrant pandanus leaf extract at concentrations of 30%, 50%, and 70%, a negative control group of a shampoo base, and a positive control group of a shampoo containing 1% selenium sulfide under the brand name Selsun. The analysis used was the One-Way ANOVA test. The shampoo preparation of fragrant pandanus leaf extract demonstrated antifungal activity against Malassezia furfur, with inhibition zones obtained at a 30% concentration (15.83 mm), 50% concentration (18.68 mm), 70% concentration (21.89 mm), positive control (21.36 mm), and negative control (0 mm). The 70% Fragrant pandan (Pandanus amaryllifolius Roxb.) leaf extract shampoo preparation is the best formulation because it exhibits optimal physical characteristics and produces the greatest inhibition against Malassezia furfur.
Potensi Antibakteri Fermentat Nira Siwalan oleh Bacillus subtilis terhadap Staphylococcus aureus Abdullah, Fatih; Pakan, Prisca Deviani; Hutasoit, Regina Marvina; Amat, Anita Lidesna Shinta
JUKEJ : Jurnal Kesehatan Jompa Vol 5 No 1 (2026): JUKEJ: Jurnal Kesehatan Jompa
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jkj.Vol5.Iss1.2501

Abstract

Fermentasi Bacillus subtilis menggunakan nira siwalan (Borassus flabellifer L.) sebagai sumber karbon telah dilakukan untuk mengevaluasi aktivitas antibakterinya terhadap Staphylococcus aureus. Penelitian ini merupakan true experimental dengan rancangan post-test only control group design. Kelompok perlakuan diberi nira siwalan pada konsentrasi 10%, 20%, dan 30%, sedangkan kelompok kontrol negatif menggunakan aquadest steril. Aktivitas antibakteri diuji dengan metode difusi cakram, dan data dianalisis menggunakan uji One Way ANOVA diikuti uji Dunnett T3. Hasil penelitian menunjukkan bahwa produk fermentasi menghasilkan zona hambat dengan diameter berkisar 18,87–22,29 mm pada seluruh konsentrasi perlakuan, yang secara signifikan berbeda dari kontrol negatif (p = 0,000). Disimpulkan bahwa nira siwalan dapat dimanfaatkan sebagai media fermentasi Bacillus subtilis untuk menghasilkan senyawa antibakteri.
Co-Authors Abdullah, Fatih Anita Lidesna Shinta Amat Artawan, I Made Christina Olly Lada Damanik, Efrisca M. Br Damanik, Efrisca M. Br. Deri Riskiyanti Tallo Manafe Dhenge, Neumensia Febrianti Djahi, Sri Nur Nur Saidah Dupe, Shita Anggenella E D, Maria Agnes Edon, Cindy Marie Agnes Lorenza Aurelia Flugentius, Bartolomeus Umbu Foni, Maria Laranita Meak Go, Dinsella Go, Stephannie Felicia Hutasoit, Regina M Hutasoit, Regina Marvina Ina Tuto, Yolanda Yasinta Indriarini, Desi Jumba, Cynthia Benedikta Kartikahadi, Anselma Dyah Koamesah, Sangguana Marthen Jacobus Konay, Soeharty Megawaty Kresnawati Wahyu Setiono Lidia, Kartini Maromon, Yeyen Nurina, Rr. Listyawati Pallo, Arini Aprili Pandie, Sinyo Demitrio Kurniawan Qurrota’ayun, Aisyah Rahmaningtyas, Dewinda Rambu Kareri, Dyah Gita Rante, Su Djie To Ratu Edo, Megaputri Yoriska Ratu, Kristian Riantoby, Raphaeline Murtiastari Rini, Desi Indria Riwu, Magdarita Sagita, Sidarta Septyowati, Mega Ayu Sequera, Maria Trisya Goncalves Seran, Dania Ekasanti M. Setianingrum, Elisabeth Levina Sari Setiawan, I Made Buddy Suki, Alce Apri Feranita Sumbayak, Anastasia Emma Reinaita Supardi, Fretrien Jiliamarch Syafira, Nadhifa Ainun Tandang, Fransiskus Tarigan, Gloria Josephin Thaal, Mario Bernardo Woda, Rahel Rara Wungouw, Herman Pieter L Zefania, Zefania