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All Journal Ngayah: Majalah Aplikasi IPTEKS Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Pharmaceutical Journal of Indonesia Jurnal Karinov Widyadari : Jurnal Pendidikan Jurnal Ilmiah Medicamento Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Jurnal Insan Farmasi Indonesia Usadha Borneo Journal of Pharmacy Bhamada: Jurnal Ilmu dan Teknologi Kesehatan (E-Journal)
Megawati, Fitria
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Journal : Usadha

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Pengetahuan dan Sikap Pasien terhadap Swamedikasi Pemilihan Obat Tradisional dan Konvensional di Apotek Dharma Medika Badung Susianti, Luh; Megawati, Fitria; Agus Adrianta, Ketut
Usadha Vol 3 No 1 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i1.7220

Abstract

  According to the World Health Organization (WHO), self-medication is choosing and using modern medicine, herbal medicine, or traditional medicine to reduce or overcome a disease or disease symptoms. The implementation of self-medication must be distinct from the use of traditional medicine and conventional medicine, where preferences for drug selection are greatly influenced by knowledge and attitude factors. This research aimed to determine the level of knowledge and attitudes toward choosing traditional and conventional medicines and self-medication in the Dharma Medika Badung Pharmacy patients. The research design used was observational descriptive, and the sampling technique was carried out using the accidental sampling method. A total of 68 respondents met the inclusion and exclusion criteria. The instrument in this research was a closed questionnaire with 14 questions, where the questionnaire's validity and reliability were first tested. The results showed that the level of knowledge of the respondents with "Good" criteria is 63%, "Fair" criteria is 28%, "Not Good" is 6%, and "Not Good" is 3%. Most patients at the Dharma Medika Badung Pharmacy have a good level of knowledge regarding the choice of traditional and conventional medicines, with respondents' attitudes tending to be positive towards conventional medicines compared to traditional medicines in terms of self-medication
Tingkat Pengetahuan Masyarakat tentang Obat Tradisional di Banjar Pejeng Aji Tegalalang Gianyar Wiradana, Dewa Gde Adi; Dewi Agustini, Ni Putu; Tangkas Suwantara, I Putu; Megawati, Fitria
Usadha Vol 2 No 3 (2023): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i3.7287

Abstract

Traditional medicine is more widely used by people in rural areas because it is easy to obtain and easy to obtain at relatively cheap prices. Traditional medicine has the ability to cure various kinds of diseases with ingredients that have been trusted for generations. The purpose of this study was to find out how far the level of public knowledge about traditional medicine in Banjar Pejeng Aji, Tegalalang, Gianyar. This research is a type of observational research that is descriptive in nature where data collection techniques are carried out using questionnaires. This research was conducted in Banjar Pejeng Aji, Tegalalang, Gianyar with a population of 254 heads of families and a sample of 80 respondents with an age range of 17-65 years was obtained. The data obtained from the research is then processed by calculating the percentage value of the respondents' answers. The results of the analysis of the questionnaire data obtained from 80 respondents showed that the level of public knowledge in Banjar Pejeng Aji, Tegalalang, Gianyar was in the Good category, where out of 80 respondents who were the research sample 75 respondents (93.75%) respondents had good knowledge, 5 respondents (6.25%) had sufficient knowledge and 0 (0%) respondents had less knowledge
Kajian Etnofarmasi Kelompok Masyarakat Banjar Saraseda Tampaksiring Gianyar Bali Puspita Wati, Ni Putu; Anita Dewi, Ni Luh Kade Arman; Suradnyana, I Gede Made; Kusuma Yuda, I Putu Era Sandhi; Cahyaningsih, Erna; Megawati, Fitria
Usadha Vol 2 No 3 (2023): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i3.7376

Abstract

  The use of ethnopharmaceutical practices remains widespread in Bali, as this knowledge has been passed down through generations. Although the Balinese people still strongly uphold their traditional healing systems and have long utilized plants as medicinal ingredients, there is still limited research documenting the diversity of plant species recorded in the Usadha manuscripts along with their therapeutic uses. This study aimed to inventory medicinal plants that are still used by the community in Banjar Saraseda, Tampaksiring, Gianyar, Bali. The study employed a descriptive design, with data collected through interviews to obtain information from respondents regarding local plant names, therapeutic uses/indications, parts of the plant utilized, and methods of preparation and application. The data were analyzed descriptively and presented in tables. Based on the ethnopharmacological survey conducted in Banjar Saraseda, Tampaksiring, Gianyar, Bali, a total of 20 medicinal plant species were recorded. The most frequently used plant parts were leaves (75%), followed by rhizomes (15%) and fruits (10%). The primary methods of preparation included boiling (65%), pounding (15%), grating, crushing, brewing, and direct use (each 5%). Based on therapeutic indications, the plants were mainly used to treat fever (20%), muscle pain and gout (20%), hypertension (20%), skin itching (10%), diabetes (10%), and to manage wounds, diarrhoea, haemorrhoids, and gastritis (each 5%). This study demonstrates that the Banjar Saraseda community in Tampaksiring, Gianyar, Bali continues to preserve traditional knowledge in the use of medicinal plants that has been inherited through generations.
Tingkat Pengetahuan Penggunaan Obat Tradisional dalam Pengobatan Swamedikasi pada PKK Banjar Tegal Buah Denpasar Barat Purnama Sari, Ni Kadek Akari; Tangkas Suwantara, I Putu; Udayana Antari, Ni Putu; Megawati, Fitria; Dewi Agustini, Ni Putu
Usadha Vol 3 No 1 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i1.7577

Abstract

  Treatment using traditional medicine has become integrated into Indonesian society and is used to treat health problems through self-medication. Traditional medicine is a nation's cultural heritage that needs to continue to be preserved and developed to support health development. This research aims to find out how self-medication uses traditional medicine in the PKK Banjar Tegal Buah West Denpasar. This type of research is quantitative survey research with data collection techniques using questionnaires and using a Likert scale in conducting surveys with questionnaire measuring instruments. This research was conducted from April to May 2023. The population in this study were all PKK mothers who had carried out self-medication using traditional medicine and the sample in this study was 100 respondents. The instrument used was a questionnaire sheet with 20 questions. Based on the results of research on the level of knowledge of the use of traditional medicine in 100 PKK respondents with the criteria for a good level of knowledge, 88 people (88%) while 12 people (12%) of respondents were included in the sufficient category.
Perbandingan Mutu Fisikokimia Virgin Coconut Oil (VCO) dengan Metode Enzimatis dan Fermentasi Alami Mutu Fisikokimia Virgin Coconut Oil (VCO) dengan Metode Enzimatis dan Fermentasi Alami Dewi Maharani Indah Sari, Ni Komang; Chandra Wibawa, Agung Ari; Pramitha, Dewa Ayu Ika; Megawati, Fitria
Usadha Vol 3 No 3 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i3.7498

Abstract

VCO is obtained from fresh, old coconut (Cocos nucifera L) flesh through a simple process without heating. Making VCO can be done by several methods, namely enzymatic methods and natural fermentation. The enzyme used in the manufacture of VCO is bromelain enzyme powder. The purpose of this study was to determine differences in the physicochemical quality of Virgin Coconut Oil (VCO) obtained by natural fermentation methods and VCO obtained by enzymatic methods adding 10% bromelain enzyme. The type of research used is experimental research conducted in the laboratory. The results obtained were then evaluated to determine the physicochemical quality of enzymatic VCO and natural fermentation. Physicochemical test parameters include a water content test performed by the gravimetric method and a free fatty acid test carried out by the titrimetric method. Based on the research that has been done, the highest average yield of VCO with the addition of bromelain enzyme powder is (24.45 ± 0.06) %. The results of the pH test on sample 1 (S1) and sample 2 (S2) obtained a pH value of 6. Testing the water content of the two samples S1 and S2 obtained results (4.018 ± 1.93) and (7.949 ± 2.57) %, with statistical testing getting p> 0.05 where there is no significant difference between the two samples. Tests for free fatty acid levels in samples S1 and S2 yielded (0.0086 ± 0.003055) % and (0.0106 ± 0.004619) %, with statistical testing yielding p > 0.05 after being tested by Kruskal Wallis, no there is a significant difference between the two samples. The enzymatic production of VCO has the advantage of obtaining more yield with the same quality as naturally fermented VCO.
Pengaruh Polimorfisme Gen terhadap Risiko Penyakit Gagal Ginjal Kronis: Narrative Review Handani, Dewa Ayu Sri; Megawati, Fitria
Usadha Vol 3 No 3 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i3.10956

Abstract

Chronic Kidney Disease (CKD) is an escalating global health issue, particularly in Indonesia. CKD is characterized by a progressive and irreversible decline in renal function, with diabetes mellitus and hypertension as primary risk factors. Genetic polymorphisms, variations in DNA sequences that affect gene function and protein expression, play a critical role in CKD risk and progression. This narrative review examines the role of genetic polymorphisms in CKD risk based on available literature. Scientific articles were sourced from PubMed, ScienceDirect, Google Scholar, and Scopus using keywords related to genetic polymorphisms and CKD. From the 441 articles identified, selection was based on relevance, sample size, and article completeness. Several genetic polymorphisms were found to have significant associations with increased CKD risk, including Renalase (rs2296545), GSTO1 (rs2164624), GSTO2, MMP3 (rs35068180), and MGP (rs4236), among others such as CYP24A1, GPX1, UMOD, CYP2C8, CYP4A11, EPHX2, SPP1, and BGLAP. These polymorphisms influence mechanisms such as blood pressure regulation, oxidative stress, inflammation, and tissue calcification, all contributing to CKD progression. In conclusion, genetic polymorphisms are crucial in CKD risk, offering insights for more personalized approaches in diagnosing, preventing, and treating this condition. These findings support the development of more effective, genetics-based treatment strategies in the future.
Identifikasi Senyawa Fitokimia dan Uji Aktivitas Antioksidan pada Cascara (Coffea arabica L.) Sasadara, Maria Malida Vernandes; Cahyaningsih, Erna; Yuda, Putu Era Sandhi Kusuma; Handani, Dewa Ayu Sri; Dewi, Ni Luh Kade Arman Anita; Megawati, Fitria; Tirtayasa, Gede Agus Ari
Usadha Vol 4 No 1 (2025): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v4i1.12181

Abstract

Cascara refers to the dried husk of coffee cherries. It has garnered significant attention in recent research due to its phytochemical composition and potential health benefits. Several studies have highlighted the presence of bioactive compounds and the antioxidant activity exhibited by cascara. This study aims to investigate the phytochemical content and antioxidant potential of cascara. The cascara was extracted using the maceration method with 96% ethanol, followed by phytochemical screening for alkaloids, flavonoids, tannins, saponins, terpenoids, steroids, and quinones using standard color reactions in test tubes. Antioxidant activity was assessed via the DPPH (2,2-diphenyl-1-picrylhydrazyl) assay, with ascorbic acid as a reference compound. The phytochemical profile of the extract was identified using gas chromatography-mass spectrometry (GC-MS). The findings indicated that cascara contains alkaloids, flavonoids, tannins, saponins, and triterpenoids. GC-MS analysis identified caffeine, hexadecanoic acid (methyl ester), and hexadecanoic acid (ethyl ester) as the predominant compounds in cascara. The antioxidant activity test using the DPPH method demonstrated that the ethanol extract of cascara possesses moderate antioxidant potential, with an average IC50 value of 108.49 ± 1.28 ppm. Ascorbic acid, the reference compound used in this study, yielded an IC50 of 2.53 ppm, categorized as very strong. This research underscores cascara’s potential as a valuable source of antioxidants with significant health benefits, influenced by geographic factors affecting its bioactive compound profile. Consequently, cascara holds promise for further development as a raw material for functional health-promoting products.
Identifikasi Senyawa Flavonoid dan Aktivitas Antioksidan Ekstrak Etanol Buah Dewandaru (Eugenia uniflora L.) Santoso, Puguh; Megawati, Fitria; Cintya Purnama Sari, Ni Wayan; Linda Paramita, Ni Kadek
Usadha Vol 1 No 3 (2022): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v1i3.4588

Abstract

Indonesia is a country with abundant natural wealth. Almost all kinds of plants can grow in this country. Most have been used since ancient times to treat various diseases. One of the efficacious plants used as medicine is the Dewandaru fruit (Eugenia uniflora L.). This study aims to identify the presence of flavonoid compounds in the Dewandaru fruit (Eugenia uniflora L.) and test the in vitro activity of the ethanol extract of the Dewandaru fruit. Dewandaru fruit extract (Eugenia uniflora L.) was prepared using the maceration extraction method with 96% ethanol solvent. The extraction process was carried out three times. The extract obtained was concentrated in a rotary evaporator at 40-45 °C and then dried in an oven at 40°C. The extracts obtained were identified by means of ultraviolet visible spectrophotometry thin-layer chromatography. obtained showed a positive reaction in the pre-test of flavonoids seen from the separation of red and from the separation of orange stains on thin-layer chromatography. The results of the in vitro test for the antioxidant activity of the ethanol extract of Dewandaru fruit showed an IC50 activity of 53.44 ppm.
Review: Pemanfaatan Tanaman sebagai Fitoterapi pada Diabetes Mellitus Dewi, Ni Luh Kade Arman Anita; Prameswari, Putu Nimas Diyah; Cahyaningsih, Erna; Megawati, Fitria; Agustini, Ni Putu Dewi; Juliadi, Debby
Usadha Vol 1 No 3 (2022): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v1i3.5562

Abstract

Diabetes is a chronic disease that occurs due to high levels of sugar in the blood, this can occur when the pancreas does not produce enough insulin (a hormone that regulates blood sugar or glucose), or when the body cannot effectively use the insulin it produces. Management of DM patients can be carried out with non-pharmacological and pharmacological therapies. The method used in the journal review was to search for the keyword "diabetes mellitus herbal medicine" for clinical studies on plant-derived products for the treatment of diabetes mellitus. Search terms included “phytotherapy”, “phytochemicals”, “medicinal plant products”, “herbal medicine”, and “diabetes mellitus”. Involving plant-derived compounds and pigmentation as outcome measures were included. In this review article, 30 journals were collected from which the objectives and results of the research in the journal were obtained. The goal is as an alternative management treatment to control blood sugar levels. For some of the compounds we discuss, among others: Flavonoids, Allicin, Lectins, Alkaloids, Andrographolid, Curcumin, Cinnamaldehyde, peptides, Phenolics, Tannins.
Efektivitas Pengobatan Tanaman Herbal dan Terapi Tradisional untuk Penyakit Tulang dan Persendian Cahyaningsih, Erna; Anita Dewi, Ni Luh Kade Arman; Udayani, Ni Nyoman Wahyu; Dwipayanti, Ni Kadek Sari; Megawati, Fitria
Usadha Vol 1 No 3 (2022): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v1i3.5596

Abstract

Bones are the body's framework that causes the body to stand upright, where the muscles are attached to allow the passage of blood vessels, where the bone marrow and nerves protect soft tissues. Traditional medicine is an effort to treat or treat other ways outside of medical science or nursing science. Indonesia is one of the countries that have the potential to develop medicinal plant cultivation and use it as an alternative treatment. This study aims to determine the effectiveness of herbal medicine and traditional therapy for bone and joint diseases. This study uses the method of literature study. The results showed that traditional herbal therapy for ball compresses, lemongrass warm compresses, cinnamon warm compresses, lavender aromatherapy warm water flower compresses, bangle rhizome compresses, and ginger warm compresses can be used for bone and joint diseases. Where there are compounds in herbal plants that have effectiveness as traditional medicine and therapy for bone and joint diseases, namely flavonoids, quercetin, curcumin, 6-gingerol and shogaol, alkaloids, steroids, and saponins.
Co-Authors Agung Ari Chandra Wibawa Agus Adrianta, Ketut Agustini, Ni Putu Dewi Amesti Dewi , Ni Made Wahyuni Anita Dewi, Ni Luh Kade Arman Antara, I Putu Satria Artini, Ni Putu Eka Chandra Wibawa, Agung Ari Cintya Purnama Sari, Ni Wayan Darmayanti, Ni Wayan Debby Juliadi Dewa Ayu Ika Pramitha Dewi Agustini, Ni Putu Dewi Maharani Indah Sari, Ni Komang Dewi, Ni Made Sintia Dwipayanti, Ni Kadek Sari Ekayanti, Ni Luh Firda Erna Cahyaningsih Firda Ekayanti, Ni Luh Fredinan Yulianda Gusti Ayu Putu Laksmi Puspa Sari Handani, Dewa Ayu Sri I Made Dedy Ariawan I Putu Tangkas Suwantara Krismayanti, Ni Luh Putu Dian Kusuma Yuda, I Putu Era Sandhi Linda Paramita, Ni Kadek Mendra, Ni Nyoman Yudianti Meriyani, Herleeyana Ni Luh Kade Arman Anita Dewi Ni Made Dharma Shantini Suena Ni Made Dwi Mara Widyani Nayaka Ni Made Sukma Sanjiwani Ni Nyoman Wahyu Udayani NI PUTU AYU MIRAH MARIATI Ni Putu Udayana Antari Ni Wayan Trisna Dewi P Purwanto Paramitha, Dewa Ayu Ika Prameswari, Putu Nimas Diyah puguh santoso, puguh Purnama Sari, Ni Kadek Akari Puspita Wati, Ni Putu Putra Hilmi Prayitno Putra, I Made Agus Sunadi Putu Era Sandhi Kusuma Yuda Ratna Wulandari Sasadara, Maria Malida Vernandes Suardika, I Wayan Gede Suradnyana, I Gede Made Susianti, Luh Tirtayasa, Gede Agus Ari Udayana Antari, Ni Putu Wardani, I Gusti Agung Ayu Kusuma Wibowo, Yosi Irawati Widiari, Ni Nyoman Sri Wintariani, Ni Putu Wiradana, Dewa Gde Adi Yana, I Gusti Agung Ari Kusuma