Article Per Year (5 Year)
p-Index From 2021 - 2026
2.863
P-Index
This Author published in this journals
All Journal Jurnal Farmasi Klinik Indonesia Majalah Obat Tradisional Jurnal Biologi Tropis Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) Journal of Pharmaceutical and Medicinal Sciences Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Kesehatan Tambusai Archives Pharmacia Jurnal Abdi Masyarakat Indonesia Majalah Cendekia Mengabdi Jurnal Pengabdian Masyarakat dan Riset Pendidikan Journal of Innovative and Creativity Jurnal Abdimas Multidisiplin JURNAL FLOBAMORATA MENGABDI
Cahyani Purnasari
Universitas Nusa Cendana
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

Published : 21 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 21 Documents
Search

 1   2   3 
Analysis of the GC-MS Volatile Compound Profile and Antibacterial Activity of 95% Ethanolic Extract of Siam Weed (Chromolaena odorata L.) Leaves from Kupang Regency Against Staphylococcus aureus Saingo, Mathias Endrico; Regaletha, Tadeus A. L.; Purnasari, Cahyani; Kolobani, Matias Nataniel
Jurnal Biologi Tropis Vol. 26 No. 3 (2026): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i3.12895

Abstract

The need for new antibacterial medicines derived from natural sources is highlighted by the dangerous bacterium Staphylococcus aureus, which causes a variety of diseases and is increasingly linked to antibiotic resistance. The leaves of Chromolaena odorata (L.) contain a variety of bioactive compounds that may have antibacterial qualities. This study aimed to characterize the metabolite profile of the 95% ethanol extract of C. odorata leaves using gas chromatography–mass spectrometry (GC-MS) and evaluate its antibacterial activity against S. aureus. This true experimental post-test-only control group study was conducted from January to May 2026 using leaves collected from Mata Air Village, Kupang Tengah District, Kupang Regency, East Nusa Tenggara, Indonesia. Antibacterial assays were performed in four replicates using the disk diffusion method at extract concentrations of 5–25%. GC-MS identified 118 compounds, with ethyl palmitate, α-linolenic acid, phytol, stigmasterol, squalene, caryophyllene oxide, and α-muurolol as dominant metabolites that may contribute to the observed antibacterial activity based on previous studies. S. aureus was inhibited by the extract in a concentration-dependent manner; inhibition zones increased from 8.03 ± 0.04 mm (5%) to 11.41 ± 0.13 mm (25%), and there were significant differences between treatments (one-way ANOVA, p < 0.001). This study shows how GC-MS metabolite profiling and antibacterial assessment of the 95% ethanol extract of C. odorata can be combined in a unique way. These results suggest that the extract has antibacterial action against S. aureus and could be a source of natural antibacterial chemicals.
Co-Authors Alim, Anggriani Angela Aloisius Masan Kopon Audrey Gracelia Riwu Burhanuddin Taebe Christiana Lethe Damang, Yulien Brigita Deif Tunggal Herlina Rante Insani Fitrahulil Jannah Jannah, Insani Fitrahulil Kale, Maria Laurenci Fanny Permata Kasim, Hasyim Kolobani, Matias Nataniel Mabu, Concitha Katarina Neno Magi Melia Tanggu Rame Magi Melia Tanggu Rame Maria Laurenci Fany Permata Kale Marianti A Manggau Mathias Nathaniel Kolobani Mawo, Yoseph Putra Albertino Mellania Belastrada Lau, Maria Muntasir, Muntasir Neolaka, Yantus A B Nimas Prita Rahajeningtyas Kusuma Wardani Nur Oktavia Nurina, Rr. Listyawati Nurul Fatmawati Pua Upa Oktavia, Nur Permatasari, Rr. Lilis Intan Pua Upa, Nurul Fatmawati Putri, Aeni Regaletha, Tadeus A. L. Regaletha, Tadeus AL. Riwu, Magdarita Sabaat, Jeanet Anggiany Saingo, Mathias Endrico Sarifudin, Barbara Azalya Syahrir Syahrir Syahrir Syahrir Tadeus Andrea Lada Regaletha Tadeus Andreas Lada Regaletha Tanggung, Agatha Febryani Charmy Un Lala, Willybrordus Dewanto Upa, Fatmawati Pua Upa, Nurul Fatmawati Pua Wardani, Nimas Prita Rahajengningtyas Kusuma Yohana Krisostoma Anduk Mbulang