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All Journal Jurnal Farmasi Klinik Indonesia Majalah Obat Tradisional Jurnal Biologi Tropis Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) Journal of Pharmaceutical and Medicinal Sciences Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Kesehatan Tambusai Archives Pharmacia Jurnal Abdi Masyarakat Indonesia Majalah Cendekia Mengabdi Jurnal Pengabdian Masyarakat dan Riset Pendidikan Journal of Innovative and Creativity Jurnal Abdimas Multidisiplin JURNAL FLOBAMORATA MENGABDI
Cahyani Purnasari
Universitas Nusa Cendana
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Phytochemical Study and Antioxidant Activity of Anti-Aging Cream from Three Rote Plants Muntasir Muntasir; Cahyani Purnasari; Nurul Fatmawati Pua Upa
Journal of Innovative and Creativity Vol. 5 No. 3 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v5i3.3450

Abstract

This study examines the antioxidant potential of three plants used by the people of Rote Ndao in skin care, namely Puteh Wood (Alstonia scholaris), Kesambi (Schleichera oleosa), and Moringa (Moringa oleifera). The background of the study was based on skin aging triggered by oxidative stress due to free radicals. The research objectives were to identify active phytochemical compounds, formulate the three extracts into creams, and analyze their potential synergism and antioxidant activity in a descriptive-exploratory manner. Extraction using 70% ethanol was carried out by maceration method, while phytochemical identification was applied by color reaction and precipitation tests for alkaloids, flavonoids, tannins, saponins, terpenoids, and steroids. Vanishing cream-based cream formulation was successfully made with good physical characteristics, namely homogeneous, pH 6.8, and spreadability of 5.7 cm. Qualitative antioxidant activity test using DPPH method showed a rapid change of DPPH purple color to pale yellow in mixed extracts and creams, indicating stronger antioxidant activity than single extracts. The results indicate the presence of potential antioxidant compounds in all three plants and an indication of synergistic effects between extracts that may come from the interaction of different classes of phytochemical compounds. These findings provide an important basis for more in-depth quantitative studies in the development of natural ingredient-based antioxidant products. Keywords: Anti-aging, Phytochemical, Cream, Polyherbal, Synergism, Qualitative, Rote Ndao, DPHH
Peningkatan Pengetahuan dan Keterampilan Tenaga Kependidikan Melalui Pelatihan Bantuan Hidup Dasar di Program Studi Pendidikan Dokter FKKH Universitas Nusa Cendana Nimas Prita Rahajeningtyas Kusuma Wardani; Deif Tunggal; Syahrir Syahrir; Insani Fitrahulil Jannah; Audrey Gracelia Riwu; Maria Laurenci Fany Permata Kale; Nurul Fatmawati Pua Upa; Cahyani Purnasari; Mathias Nathaniel Kolobani
Jurnal Flobamorata Mengabdi Vol. 3 No. 1 (2025): JURNAL FLOBAMORATA MENGABDI
Publisher : Program Studi Pendidikan Guru Sekolah Dasar, Fakultas Keguruan dan Ilmu Pendidikan, Universitas Muhammadiyah Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51494/jfm.v3i1.2433

Abstract

Abstrak: Henti jantung merupakan kasus kegawatdaruratan medis dimana jantung berhenti berfungsi secara medadak sehingga menimbulkan gangguan hemodinamik tubuh hingga dapat menimbulkan kematian jika tidak ditangani segera. Tindakan bantuan hidup dasar (BHD) merupakan serangkaian tindakan pertolongan pertama yang dapat dilakukan untuk memulihkan fungsi pernapasan dan sirkulasi pada seseorang yang mengalami henti jantung. Pelatihan BHD pada tenaga kependidikan yang merupakan kelompok non-medis di lingkungan program studi Pendidikan dokter FKKH Universitas Nusa Cendana bertujuan untuk meningkatkan kapabilitas pegawai dalam melakukan pertolongan pertama serta meningkatkan kesiapsiagaan pegawai dalam kondisi kegawatdaruratan kejadian henti jantung terutama di lingkungan kerja. Metode yang digunakan adalah pelatihan kepada 20 tenaga kependidikan dengan menggabungkan teori, diskusi interaktif, serta praktik simulasi. Hasil dari pelatihan didapatkan peningkatan pengetahuan diukur dari nilai post-test yang jauh lebih baik dibandingkan nilai pre-test. Selain itu, didapatkan peningkatan keterampilan dan kepercayaan diri dari peserta dalam melakukan tindakan BHD pada kasus henti jantung. Kesimpulannya, kegiatan pelatihan BHD bagi tenaga kependidikan di lingkungan program studi Pendidikan Dokter, FKKH Universitas Nusa Cendana terbukti efektif dalam meningkatkan pengetahuan dan keterampilan peserta pelatihan.
EDUKASI HERBAL: SOLUSI MINUMAN SEHAT UNTUK MENCEGAH BATUK DAN PILEK PADA ANAK DI DESA NUSAEN, FATULEU TENGAH, KABUPATEN KUPANG Muntasir Muntasir; Muhajirin Dean; Mathias Nathaniel Kolobani; Cahyani Purnasari; RR. Listyawati Nurina; Nurul Fatmawati Pua Upa; Tadeus Andrea Lada Regaletha
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 6 No. 2 (2025): Volume 6 No. 2 Tahun 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v6i2.42692

Abstract

Kesehatan adalah aspek penting dalam kehidupan, terutama di daerah pedesaan yang memiliki akses terbatas terhadap layanan kesehatan. Batuk dan pilek merupakan penyakit umum yang sering menyerang anak-anak, khususnya balita. Penelitian ini bertujuan untuk meningkatkan pengetahuan masyarakat Desa Nunsaen mengenai penggunaan tanaman obat sebagai pencegahan batuk dan pilek melalui edukasi praktis. Metode yang digunakan meliputi ceramah, demonstrasi pembuatan minuman herbal, uji organoleptik produk, dan diskusi interaktif dengan 30 peserta dari berbagai latar belakang. Hasil evaluasi menunjukkan peningkatan pengetahuan yang signifikan; sebelum pelatihan, hanya 25% peserta yang mengetahui manfaat tanaman herbal, sedangkan setelah pelatihan, angka tersebut meningkat menjadi 100%. Selain itu, semua peserta menyatakan akan merekomendasikan penggunaan minuman herbal untuk pencegahan batuk dan pilek pada anak. Kesimpulan dari kegiatan ini adalah bahwa edukasi mengenai tanaman obat efektif dalam meningkatkan kesadaran masyarakat tentang alternatif pengobatan alami dan mendorong pemanfaatan sumber daya lokal untuk kesehatan yang lebih baik.
Ethnomedicine and Medicinal Plant Conservation Study in the Oben Village Community, Nekamese District, Kupang Regency Sabaat, Jeanet Anggiany; Muntasir, Muntasir; Purnasari, Cahyani
Jurnal Biologi Tropis Vol. 26 No. 3 (2026): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i3.12732

Abstract

Ethnomedicine represents indigenous knowledge regarding the use of medicinal plants for healthcare and plays an important role in supporting biodiversity conservation. However, documentation of ethnomedicinal knowledge in Oben Village, Nekamese District, Kupang Regency, remains limited, creating a risk of knowledge erosion across generations. This study aimed to document medicinal plant diversity, traditional utilization patterns, and community-based conservation practices in Oben Village. A descriptive qualitative approach was employed involving 30 purposively selected respondents. Data were collected through interviews, field observations, and documentation, and analyzed descriptively. A total of 44 medicinal plant species belonging to various families were identified and used to treat 20 categories of diseases. Leaves were the most frequently utilized plant part (55%), while boiling was the predominant preparation method (66%), followed by oral administration as the primary mode of use. The community also applies multi-species herbal formulations for certain ailments, reflecting a rich body of local therapeutic knowledge. Conservation is primarily conducted through home gardens, mixed cropping systems, and the sustainable use of naturally growing plant resources. These findings highlight the richness of local ethnomedicinal knowledge and demonstrate its contribution to both primary healthcare and in situ plant conservation. The documented information provides a scientific basis for biodiversity conservation, preservation of indigenous knowledge, and future pharmacological investigations of medicinal plant resources.
Phytochemical Analysis of Forest Betel Leaves (Piper aduncum L.) Using GC-MS and Antibacterial Activity Against Staphylococcus aureus Mawo, Yoseph Putra Albertino; Muntasir, Muntasir; Purnasari, Cahyani; Dean, Muhajirin
Jurnal Biologi Tropis Vol. 26 No. 3 (2026): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i3.12834

Abstract

Skin infections due to Staphylococcus aureus continue to be a major health issue, particularly with the increase in antibiotic resistance. Traditionally, forest betel leaves (Piper aduncum L.) have been utilized for treating wounds and skin ailments. The goal of this research is to explore the chemical components of a 95% ethanol extract of Piper aduncum L. leaves through GC-MS and to evaluate its effectiveness against Staphylococcus aureus ATCC 25923. This research was carried out experimentally using a design featuring a control group. The extract was prepared via maceration with 95% ethanol. Chemical analysis was conducted using GC-MS, while the antibacterial properties were examined through the disk diffusion technique at concentrations of 0.5% w/v, 1% w/v, 2% w/v, 5% w/v, and 10% w/v. Data analysis was performed using one-way ANOVA along with Tukey’s post hoc test. The yield from the extract was 6.42%. The GC-MS analysis identified compounds including hexadecanoic acid, phytol, and piperlonguminine. The extract demonstrated inhibition of Staphylococcus aureus growth at all concentrations tested, with inhibition zones measuring from 6.65 to 12.72 mm. The statistical analysis indicated significant differences between the treatment groups (p < 0.001). In conclusion, the 95% ethanol extract of wild betel leaf (Piper aduncum L.) contains bioactive compounds and shows antibacterial effects against Staphylococcus aureus.
Antibacterial Activity Test of 70% Ethanol Extract of Kersen Leaves (Muntingia calabura L.) against Cutibacterium acnes Un Lala, Willybrordus Dewanto; Regaletha, Tadeus A. L.; Purnasari, Cahyani; Jannah, Insani Fitrahulil
Jurnal Biologi Tropis Vol. 26 No. 3 (2026): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i3.12838

Abstract

Acne ranks among the most prevalent skin issues and is linked to infection by Cutibacterium acnes. The rising rates of antibiotic resistance seen in Cutibacterium acnes necessitate the exploration of alternative plant-based treatments with antibacterial properties. One such plant that has demonstrated these antibacterial effects is the kersen leaf (Muntingia calabura L.). This research aimed to evaluate the antibacterial effects of a 70% ethanol extract of kersen leaves (Muntingia calabura L.) on the proliferation of Cutibacterium acnes. The research employed a true experimental design featuring a posttest only control group. The treatment categories included a positive control using Clindamycin, a negative control with sterile aquadest, and varying concentrations of kersen leaf extract at 1%, 2%, 4%, 8%, and 12%, with each group replicated four times. Data were assessed using the One-Way ANOVA method. The findings of the antibacterial test indicated that the 70% ethanol extract of kersen leaves effectively inhibited the growth of Cutibacterium acnes. The One-Way ANOVA analysis produced a p-value of less than 0.0001, which is lower than α = 0.05, signifying a notable discrepancy in the average inhibition zone diameters across the treatment groups. Ethanol extract from kersen leaves (Muntingia calabura L.) exhibits antibacterial properties against Cutibacterium acnes growth.
Exploration of Ethnomedicine for Open Wound Treatment in The Community of Fatumuti Village, Noemuti Subdistrict, North Central Timor Alim, Anggriani Angela; Muntasir, Muntasir; Purnasari, Cahyani; Regaletha, Tadeus AL.
Jurnal Biologi Tropis Vol. 26 No. 3 (2026): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i3.12871

Abstract

Fatumuti Village, Noemuti Subdistrict, North Central Timor Regency, is served by one primary health center covering 12 villages. Most residents work in agriculture, increasing the risk of open wounds and encouraging the continued use of medicinal plants. Although ethnomedicinal studies on wound treatment have been conducted in other regions of Indonesia, this practice has never been scientifically documented in Fatumuti Village.  This study aimed to document the ethnomedicinal practices used by the Fatumuti Village community for treating open wounds, including medicinal plant diversity, plant parts used, and methods of preparation and application. Methods. A qualitative descriptive design with purposive sampling was employed. Data were collected through in-depth interviews, observation, and documentation involving 3 key informants and 27 triangulation informants from March to May 2026. Data were analyzed using the Miles and Huberman interactive model. Nineteen medicinal plant species from 13 families were identified. Leaves were the most frequently used plant part (13 species). Preparation methods included squeezing, pounding, chewing with rice, extracting sap, grating, and oil preparation, while remedies were applied topically one to three times daily, either singly or in combination. This study provides the first scientific documentation of medicinal plants used for open wound treatment in Fatumuti Village and offers baseline data for future pharmacological research and preservation of local ethnomedicinal knowledge.
Determination of Quercetin Content in Aqueous and Ethanol Extracts of Ndusuk Leaves (Melastoma malabathricum L.) Based on UV-Vis Spectrophotometric Analysis Damang, Yulien Brigita; Dean, Muhajirin; Purnasari, Cahyani; Neolaka, Yantus A. B.
Jurnal Biologi Tropis Vol. 26 No. 3 (2026): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i3.12875

Abstract

Ndusuk leaf (Melastoma malabathricum L.) is a plant containing flavonoid compounds, including quercetin, which has potential as an antioxidant, antibacterial, and antidiarrheal agent. Different types of solvents and extraction methods may affect the quercetin content obtained. This study aimed to determine and compare the quercetin content in aqueous and 95% ethanol extracts of Ndusuk leaves using UV-Vis spectrophotometry. This was a laboratory experimental study. Ndusuk leaf simplicia was extracted using the infusion method with water as the solvent and the maceration method with 95% ethanol. Quercetin content was determined using a UV-Vis spectrophotometer at a maximum wavelength of 361 nm. A quercetin standard curve was prepared at concentrations ranging from 4–12 ppm, yielding a linear regression equation of y = 0.0453x + 0.2356 with R² = 0.9942. The yields of aqueous and 95% ethanol extracts were 6.12% and 10.17%, respectively. The quercetin content in the aqueous extract was 0.84 ± 0.04 mg/g, while in the 95% ethanol extract it was 16.27 ± 0.15 mg/g. The 95% ethanol extract demonstrated significantly higher quercetin content compared to the aqueous extract. The use of 95% ethanol with the maceration method was more effective in extracting quercetin from Ndusuk leaves compared to aqueous extraction using the infusion method.
Association of Patient Characteristics and Polypharmacy with the Potential for Drug Interactions among Hypertensive Patients at Bakunase Community Health Center Tanggung, Agatha Febryani Charmy; Riwu, Magdarita; Purnasari, Cahyani; Syahrir, Syahrir
Jurnal Biologi Tropis Vol. 26 No. 3 (2026): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i3.12884

Abstract

Chronic hypertension frequently has comorbidities, necessitating the use of several drugs (polypharmacy), which raises the possibility of drug interactions. This study aimed to determine the prevalence of polypharmacy, potential drug interactions, and the association between patient characteristics, polypharmacy, and potential drug interactions among hypertensive patients at Bakunase Primary Health Center. 572 hypertensive patients' medical data from January to December 2025 were used in this analytical observational study, which used a retrospective cross-sectional approach. Drugs.com® and Medscape® were used to identify potential drug interactions, and the Chi-square test was used to evaluate the results. According to the findings, 32.3% of patients had polypharmacy and 63.7% of patients had possible drug interactions. While polypharmacy was substantially linked to possible drug interactions (p = 0.001), age was significantly linked to both polypharmacy and potential drug interactions (p = 0.003). We conclude that among hypertension patients, age and polypharmacy are strongly linked to a higher likelihood of possible medication interactions.  
A Study of Community Knowledge Level Regarding the Dagusibu Program for Antibiotic Medicines in Penfui Timur Village Mabu, Concitha Katarina Neno; Regaletha, Tadeus Andreas Lada; Upa, Nurul Fatmawati Pua; Purnasari, Cahyani
Jurnal Biologi Tropis Vol. 26 No. 3 (2026): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i3.12885

Abstract

Antimicrobial resistance, treatment failure, and higher healthcare expenditures are all consequences of inappropriate antibiotic usage, which continues to be a significant public health concern. The goal of the DAGUSIBU (Get, Use, Store, and Dispose of Medicines Properly) campaign is to increase public awareness and encourage sensible medication management. This study described community knowledge regarding the DAGUSIBU program for antibiotic medicines among residents of Penfui Timur Village, Kupang Tengah District, Kupang Regency. A descriptive quantitative study was conducted from March to April 2026 involving 99 respondents selected using cluster sampling. Data were collected using a validated structured questionnaire and analyzed descriptively. Knowledge was classified into good, moderate, and poor categories based on predetermined scoring criteria. Overall knowledge of the DAGUSIBU program and antibiotic use was categorized as moderate, with scores of 66.67% and 69.56%, respectively. The highest score was found in obtaining medicines (74.75%), whereas the lowest was in disposing of medicines (57.37%). Most respondents had a moderate level of knowledge. Community knowledge regarding the DAGUSIBU program was generally moderate. The low score for medicine disposal highlights the need for targeted educational interventions to improve appropriate disposal practices and support rational antibiotic use.
Co-Authors Alim, Anggriani Angela Aloisius Masan Kopon Audrey Gracelia Riwu Burhanuddin Taebe Christiana Lethe Damang, Yulien Brigita Deif Tunggal Herlina Rante Insani Fitrahulil Jannah Jannah, Insani Fitrahulil Kale, Maria Laurenci Fanny Permata Kasim, Hasyim Kolobani, Matias Nataniel Mabu, Concitha Katarina Neno Magi Melia Tanggu Rame Magi Melia Tanggu Rame Maria Laurenci Fany Permata Kale Marianti A Manggau Mathias Nathaniel Kolobani Mawo, Yoseph Putra Albertino Mellania Belastrada Lau, Maria Muntasir, Muntasir Neolaka, Yantus A B Nimas Prita Rahajeningtyas Kusuma Wardani Nur Oktavia Nurina, Rr. Listyawati Nurul Fatmawati Pua Upa Oktavia, Nur Permatasari, Rr. Lilis Intan Pua Upa, Nurul Fatmawati Putri, Aeni Regaletha, Tadeus A. L. Regaletha, Tadeus AL. Riwu, Magdarita Sabaat, Jeanet Anggiany Saingo, Mathias Endrico Sarifudin, Barbara Azalya Syahrir Syahrir Syahrir Syahrir Tadeus Andrea Lada Regaletha Tadeus Andreas Lada Regaletha Tanggung, Agatha Febryani Charmy Un Lala, Willybrordus Dewanto Upa, Fatmawati Pua Upa, Nurul Fatmawati Pua Wardani, Nimas Prita Rahajengningtyas Kusuma Yohana Krisostoma Anduk Mbulang