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All Journal Mutiara Medika: Jurnal Kedokteran dan Kesehatan Public Health of Indonesia Jurnal Respirasi (JR) Jurnal Impresi Indonesia Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Jurnal Kedokteran Meditek
Sinaga, Bintang Yinke Magdalena
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Religion Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Profil Hemoglobin, Trombosit, dan Rasio Neutrofil Limfosit pada Pasien Kanker Kolorektal: Studi Deskriptif di RSUP Haji Adam Malik Medan Simatupang, Ruth Vanessa; Katharine; Sinaga, Bintang Yinke Magdalena; Abdillah, Hafaz Zakky
Jurnal Kedokteran Meditek Vol 31 No 5 (2025): SEPTEMBER
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v31i5.3488

Abstract

Introduction: Colorectal cancer is a global health problem with an increasing incidence. Monitoring cancer stage is crucial as it is closely related to therapeutic decisions, prognosis, and patient survival. Simple hematological parameters, such as hemoglobin, platelet count, and neutrophil-to-lymphocyte ratio, may aid in clinical evaluation. Objective: This study aimed to describe the profiles of hemoglobin, platelet count, and neutrophil-to-lymphocyte ratio in patients with colorectal cancer. Methods: The study employed a descriptive observational method with a cross-sectional approach. Secondary data were obtained from the medical records of 141 patients using the total sampling method. Data analysis was performed using descriptive statistics.  Results: Anemia was found in 83% of patients, with a higher incidence at higher stages. Normal platelet counts were observed in 80% of patients, with decreasing proportions in higher stages. Elevated NLR was found in 78% of patients and was more frequent at higher stages of disease.  Conclusion: These findings indicate the presence of anemia and a systemic inflammatory response, but not thrombocytosis. This research highlights the potential of these simple biomarkers in monitoring cancer stages and treatment strategies.  
Factors Associated with Treatment Outcome of Shorter Treatment Regimen (STR) for MultiDrug-Resistant Tuberculosis (MDR-TB) Perangin-angin, Gwanita Nawariantina; Sinaga, Bintang Yinke Magdalena; Siagian, Parluhutan; Eyanoer, Putri Chairani
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 6 No. 4 (2024): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v6i4.16123

Abstract

ABSTRACT Background: Indonesia ranked 2nd around the world for TB cases with case population continue increasing. In 2018, Shorter Treatment Regimen (STR) was introduced as a new regimen for treating MDR-TB patient. The aim of this study is to determine factors associated with treatment outcome of MDR-TB patients treated with Shorter Treatment Regimen Methods: This is a descriptive-analytic study using cross sectional design which was conducted at Adam Malik Hospital Medan. Subject was 150 patients with drug-resistant Pulmonary TB at MDR-TB polyclinics according to inclusion and exclusion criteria Results: MDR-TB patients that treated with STR was mostly < 50 years old (65.2%) and 107 subjects (70.4%) were male. The majority of subjects with comorbidity were 94 subjects (61.8%); 43 subjects (28.3%) with DM, 5 subjects (3.3%) with CHF, 3 subjects (2.0%) with HIV, 1 subject (0.7%) with DM & CHF, and 1 subject (0.7%) with DM & HIV. When evaluated the patients treatment outcome, 47.4% were cured, 6.6% were failed, 34.8% were default and 11.2% were death. A chi square test was conducted to assess association between age with treatment outcome. Age was significantly associated with treatment outcome (p=0.038) but gender and comorbidity were not associated with treatment outcome with p-value 0.152 and 0.497 (p>0,05) respectively. Conclusions: There is a significant association between age and treatment outcome but no significant association between gender and comorbidity with treatment outcome. ABSTRAK Latar Belakang: Indonesia menduduki peringkat ke-2 dunia untuk kasus TBC dengan populasi kasus yang terus meningkat. Pada tahun 2018, Shorter Treatment Regimen (STR) diperkenalkan sebagai rejimen baru untuk mengobati pasien TB-MDR. Tujuan dari penelitian ini adalah untuk mengetahui faktor-faktor yang berkorelasi dengan hasil pengobatan pasien TB-MDR yang diobati dengan Regimen STR. Metode: Penelitian ini merupakan penelitian deskriptif-analitik dengan desain cross-sectional yang dilakukan di Rumah Sakit Adam Malik Medan. Subyek penelitian adalah 150 pasien TB Paru Resisten Obat di poliklinik TB MDR sesuai kriteria inklusi dan eksklusi. Hasil: Pasien TB-MDR yang diobati dengan STR sebagian besar berusia <50 tahun (65,2%) dan berjenis kelamin laki-laki sebanyak 107 subjek (70,4%). Mayoritas subjek dengan penyakit penyerta sebanyak 94 orang (61,8%); 43 orang (28,3%) DM, 5 orang (3,3%) CHF, 3 orang (2,0%) HIV, 1 orang (0,7%) DM & CHF, dan 1 orang (0,7%) DM & HIV. Hasil pengobatan adalah 47,4% sembuh, 6,6% gagal, 34,8% putus berobat dan 11,2% meninggal. Uji chi square dilakukan untuk menilai hubungan antara usia dengan hasil pengobatan dan didapatkan nilai p = 0,038 yang menunjukkan adanya hubungan yang signifikan namun berdasarkan jenis kelamin dan penyakit penyerta ditemukan nilai p masing-masing 0,152 dan 0,497 (p>0,05) yang menunjukkan tidak ada hubungan antara jenis kelamin dan penyakit penyerta terhadap hasil pengobatan. Kesimpulan: Terdapat hubungan yang signifikan antara usia dan hasil pengobatan namun tidak ada hubungan yang signifikan antara jenis kelamin dan penyakit penyerta dengan hasil pengobatan.
FACTORS AFFECTING SUCCESSFUL PULMONARY TUBERCULOSIS TREATMENT AT STABAT HEALTH CENTER IN LANGKAT DISTRICT Nahdhia; Sinaga, Bintang Yinke Magdalena; Adriztina, Indri; Saragih, Rina Amalia Caromina; Nasution, Tetty Aman
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 7 No. 4 (2025): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v7i4.21244

Abstract

Background: Pulmonary Tuberculosis (TB) is a significant global public health problem, mainly affecting the lungs. Many factors are associated with the successful treatment of pulmonary TB patients. This study aims to analyze factors affecting the successful treatment of pulmonary TB at Stabat Health Center, Langkat District. Method: This observational analytic study used a cross-sectional design and was conducted from October 2024 to January 2025 at Stabat Health Center. All pulmonary TB patients diagnosed between 2022 and 2023 who met the inclusion and exclusion criteria were included using a total sampling approach. Data were collected from the Tuberculosis Information System and analyzed using univariate, bivariate, and multivariate analyses. Results: Comorbid diabetes mellitus (DM) (p=0.003; OR=7.01) and distance to health facility (p=0.022; OR=4.44) were significantly associated with treatment success. In contrast, age, sex, occupation, comorbid HIV infection, and treatment status did not show a statistically significant association with treatment outcomes. Conclusion: Comorbid DM had the greatest effect on successful of pulmonary TB treatment at Stabat Health Center. TB patients with Diabetes Mellitus comorbid need special attention. Further research is needed to analyze other potential factors.
Co-Authors Abdillah, Hafaz Zakky Elmeida Effendy Fotarisman Zaluchu, Fotarisman Harahap, Juliandi Hendri Wijaya, Hendri Indri Adriztina Kartini harahap Katharine Muhar, Adi Muradi Nahdhia Nasution, Tetty Aman Parluhutan Siagian Pasaribu, Ira Nurhasanah Perangin-angin, Gwanita Nawariantina Putri Chairani Eyanoer, Putri Chairani Restuti Hidayani Saragih Rina Yunita Rini Savitri Daulay, Rini Savitri Rizky, Handan Rohmawati, Lili Samodra, Yoseph Leonardo Saragih, Rina Amalia Caromina Siagian, Novi Andriani Sidabutar, Wita Lestari Simanjuntak, Christine Raphaela Tiarmauli Simatupang, Ruth Vanessa Sinaga, Joshua Princeman Siregar, Jelita Sormin, Delores Elisabeth Sundari, Rina Syarani, Fajrinur Tako, Frida Welhelmina Taufik Ashar Wahyuni, Arlinda Sari Zahra, Diandra Angelia Az