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All Journal Jurnal Ilmiah Farmasi Indonesian Journal of Pharmaceutical Science and Technology MPI (Media Pharmaceutica Indonesiana) Jurnal Ilmiah Farmasi Farmasyifa Borneo Journal Of Pharmascientech SPIN: Jurnal Kimia & Pendidikan Kimia Lombok Journal of Science Jurnal Kolaboratif Sains Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Journal Borneo Literasi: Jurnal Pengabdian Masyarakat dan Inovasi Jurnal Penelitian dan Kajian Ilmiah Kesehatan Politeknik Medica Farma Husada Mataram Jurnal Farmasi SYIFA Jurnal Farmasi dan Farmakoinformatika Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Borneo Journal of Pharmacy Jurnal Abdimas Multidisiplin Jurnal Pharma Bhakta Jurnal Sains dan Kesehatan Borneo Nursing Journal Journal of Pharmascience
Astuti, Karunita Ika
Universitas Negeri Gorontalo
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Analisis Sistem Penyimpanan Obat Emergensi Di Instalasi Farmasi Dinas Kesehatan Kabupaten Gorontalo: Analysis of the Emergency Medication Storage System at the Pharmacy Unit of the Gorontalo Regency Health Office Nazwa Nurahma T Hanapi; Endah Nurrohwinta Djuwarno; Ariani H. Hutuba; Nur Ain Thomas; Karunita Ika Astuti; Nikma Abaidata
Jurnal Kolaboratif Sains (Special Issue) Jurnal Kolaboratif Sains (JKS) - July 2026
Publisher : Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jks.v9i7.11638

Abstract

Penyimpanan obat emergensi merupakan aspek krusial dalam pelayanan kefarmasian karena berpengaruh langsung terhadap kecepatan penanganan pasien dalam kondisi kegawatdaruratan. Penelitian ini bertujuan untuk menganalisis kesesuaian sistem penyimpanan obat emergensi di Instalasi Farmasi Dinas Kesehatan Kabupaten Gorontalo berdasarkan standar Cara Distribusi Obat yang Baik (CDOB), serta mengidentifikasi faktor-faktor yang mempengaruhinya. Jenis penelitian yang digunakan adalah deskriptif dengan pendekatan observasional. Pengumpulan data dilakukan melalui observasi langsung menggunakan lembar checklist berbasis CDOB, wawancara semi terstruktur dengan Apoteker Penanggung Jawab dan petugas gudang, serta dokumentasi. Hasil penelitian menunjukkan bahwa sebagian besar aspek penyimpanan obat emergensi telah sesuai dengan standar CDOB dengan kategori sangat baik, meliputi kondisi ruangan penyimpanan (100%), suhu dan kelembapan (100%), sistem penyimpanan (100%), segregasi (100%), serta label dan identitas obat (100%). Aspek operasional penyimpanan memperoleh persentase kesesuaian sebesar 86%, sedangkan aspek pengendalian obat hanya mencapai 50% karena masih ditemukannya obat rusak dan kedaluwarsa. Faktor-faktor yang mempengaruhi sistem penyimpanan meliputi keterbatasan jumlah sumber daya manusia, belum meratanya pelatihan CDOB, kapasitas ruang penyimpanan yang terbatas pada kondisi tertentu, serta human error dalam pencatatan stok. Penerapan SOP dan sistem FEFO/FIFO telah berjalan dengan baik. Penelitian ini menyimpulkan bahwa sistem penyimpanan obat emergensi di instalasi tersebut secara umum telah memenuhi standar CDOB, namun aspek pengendalian obat masih memerlukan peningkatan pengawasan terhadap obat rusak dan kedaluwarsa. ABSTRACT Emergency medication storage is a critical aspect of pharmaceutical services, as it directly affects the speed of patient care in emergency situations. This study aims to analyze the suitability of the emergency medication storage system at the Pharmacy Unit of the Gorontalo Regency Health Office based on the Good Drug Distribution Practice (GDDP/CDOB) standards, and to identify the factors influencing it. This study used a descriptive research design with an observational approach. Data were collected through direct observation using a CDOB-based checklist, semi-structured interviews with the responsible pharmacist and warehouse staff, and documentation. The results showed that most aspects of emergency medication storage were in compliance with CDOB standards and classified as very good, including storage room conditions (100%), temperature and humidity control (100%), storage system (100%), segregation (100%), and drug labeling (100%). The operational storage aspect reached 86% compliance, while drug control only achieved 50% due to the presence of damaged and expired medications. Factors influencing the storage system included limited staffing, uneven CDOB training among personnel, limited storage capacity under certain conditions, and human error in stock recording. The implementation of SOPs and the FEFO/FIFO system was found to be well-established. This study concludes that the emergency medication storage system at the pharmacy unit generally meets CDOB standards; however, the drug control aspect still requires improved monitoring of damaged and expired medications.
Evaluasi Kelengkapan Obat pada Emergency Trolley di IGD Rumah Sakit Umum Daerah Sayang Rakyat Makassar: Evaluation of Medication Completeness in the Emergency Trolley at the Emergency Department of Sayang Rakyat Regional General Hospital Makassar Susilawaty Mantulangi; Widy Susanti Abdulkadir; Karunita Ika Astuti; Teti Sutriyati Tuloli; Multiani S. Latif
Jurnal Kolaboratif Sains (Special Issue) - Jurnal Kolaboratif Sains (JKS) - Agustus 2026
Publisher : Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jks.v9i8.11709

Abstract

Emergency trolley merupakan troli berisi obat-obatan dan alat kesehatan yang digunakan untuk penanganan kondisi darurat seperti henti jantung dan syok. Penelitian ini bertujuan untuk mengetahui kesesuaian kelengkapan obat pada emergency trolley di IGD RSUD Sayang Rakyat Makassar berdasarkan standar yang berlaku. Metode penelitian menggunakan kuantitatif deskriptif melalui observasi dan dokumentasi langsung periode Januari–Februari 2026. Sampel ditentukan dengan teknik total sampling terhadap unit emergency trolley dan seluruh stok obat di dalamnya. Hasil evaluasi kuantitas dari 21 jenis obat menunjukkan 17 jenis berkondisi lengkap (100%), namun terdapat defisit kuantitas pada 4 jenis sediaan (Amiodaron injeksi, Isosorbid dinitrat injeksi, Furosemid injeksi, dan Isosorbid dinitrat tablet 5 mg). Dari total 52 unit volume ideal, hanya tersedia 45 unit fisik di lapangan (capaian 86,54% dan defisit 13,46%). Dari aspek kualitas, ditemukan sediaan kedaluwarsa (Methyl prednisolon 125 mg injeksi dan Amiodaron injeksi) serta sediaan kritis dekat kedaluwarsa (Epinefrin injeksi dan Stesolid 5 mg), meskipun kemasan 100% baik. Kesimpulan penelitian menunjukkan bahwa kesesuaian kelengkapan obat belum sepenuhnya memenuhi standar yang telah ditentukan. ABSTRACT Emergency trolley is a cart containing medicines and medical devices used to manage emergency conditions such as cardiac arrest and shock. This study aims to determine the suitability of drug completeness in the emergency trolley at the Emergency Department (ED) of Sayang Rakyat Regional General Hospital Makassar based on applicable standards. The research method used descriptive quantitative through direct observation and documentation during January–February 2026. The sample was determined using a total sampling technique on the emergency trolley unit and all drug stocks within it. The quantity evaluation of 21 drug types showed that 17 types were complete (100%), yet a quantity deficit was found in 4 preparations (Amiodarone injection, Isosorbide dinitrate injection, Furosemide injection, and Isosorbide dinitrate tablet 5 mg). Of the total 52 ideal volume units, only 45 physical units were available in the field (achievement 86.54% and deficit 13.46%). In terms of quality, expired preparations (Methyl prednisolone 125 mg injection and Amiodarone injection) and critical near-expiry preparations (Epinephrine injection and Stesolid 5 mg) were found, although 100% of the packaging was in good condition. The study concludes that the drug completeness has not fully met the predetermined standards.
Uji Aktivitas Antibakteri Kombinasi Ekstrak Etanol Daun Miana (Coleus atropurpureus L.) dan Daun Jambu Biji (Psidium guajava L.) terhadap Pertumbuhan Bakteri Escherichia coli Masayu Syarmila Putri Abas; La Ode Aman; Multiani S. Latif; Ishak Isa; Karunita Ika Astuti
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 5 (2026): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i5.2392

Abstract

This study aimed to determine the antibacterial activity of the combined ethanol extracts of miana leaves (Coleus scutellarioides L.) and guava leaves (Psidium guajava) against Escherichia coli and to evaluate their interaction using the CompuSyn method. This laboratory experimental study employed maceration extraction with 96% ethanol, followed by phytochemical screening, antibacterial testing using the disc diffusion method, One-Way ANOVA, and Combination Index (CI) analysis. The extraction yielded 11.11% for miana leaves and 24.92% for guava leaves. Phytochemical screening confirmed the presence of flavonoids and alkaloids in both extracts. All extract combinations inhibited E. coli growth, producing inhibition zones ranging from 8.10 to 12.75 mm, indicating moderate to strong antibacterial activity. One-Way ANOVA showed no significant differences among treatment groups (p = 0.837). CompuSyn analysis revealed that most combinations exhibited antagonistic interactions (CI > 1), whereas the combination of 10% guava extract and 20% miana extract showed synergistic effects (CI < 1) in two replicates. Overall, the combined extracts demonstrated antibacterial activity against E. coli, although most combinations did not exhibit synergistic interactions.
Co-Authors Agung Biworo Akbar, Depy Oktapian Akhmad Junaidi Alista, Siti Aprilia Rahmadina Ari Surya Pratama Ariani H. Hutuba Aristha N. Putri Ayulia Dwi Sandi, Dita Baiq Nurdiana Ulfa Bella Rosalina Endah Dharmayati, Evy Eka Fitri Susiani Endah Nurrohwinta Djuwarno Faizha Putri Delia fitriyanti fitriyanti Fitriyanti, Fitriyanti Guntur Kurniawan Hadirvika Tjuthiyanda Helmina Wati Hendrya Legenda Herliana Dewi Hidayati, Listya Nor Hidayatullah, Muhammad Hiola, Faramita Ika P. Sari Ishak Isa Khoerul Anwar La Ode Aman Lusiana Dwi Wulandari Madania, Madania Mariani Masayu Syarmila Putri Abas Mohamad Reski Manno Monalissa Indriani Muhammad Nazhir Muhammad Nur Rahman Hendrawan Multiani S Latif Nazwa Nurahma T Hanapi Nikma Abaidata Norhasanah Norhasanah Noviadi, Aditya Nur Ain Thomas Nur Huda Nurul Hikmah Pangestika, Indira Adi Rahmatullah, Satrio Wibowo Rahmi Muthia Rizaldi, Gusti Rusida, Esty Restiana Saputri, Revita Sari Wahyunita Sartika Dewi Sunarti, Lisa Susilawaty Mantulangi Syahrizal Ramadhani Syaid Nofal Assegaf Teti Sutriyati Tuloli Teuku N.S. Sulaiman Uswatun Rahimah Vebruati Vebruati Wahyudin Wahyudin Widy Susanti Abdulkadir