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All Journal Althea Medical Journal Universa Medicina Jurnal Medika Malahayati Jurnal Biomedika dan Kesehatan Veterinary Biomedical and Clinical Journal JUARA: JURNAL WAHANA ABDIMAS SEJAHTERA JURNAL ABDI MASYARAKAT INDONESIA (JAMIN) Jurnal Pengabdian Masyarakat Trimedika Poltekita: Jurnal Ilmu Kesehatan
Hairunisa, Nany
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Humanities Biochemistry, Genetics & Molecular Biology Dentistry Earth & Planetary Sciences Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Veterinary Other

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STUDI LITERATUR: NYERI KEPALA PADA EPILEPSI Aswar, Andini; Hairunisa, Nany; Primandari, Rima Anindita; Larasari, Andira
Jurnal Medika Malahayati Vol 8, No 1 (2024): Volume 8 Nomor 1
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jmm.v8i1.12231

Abstract

Abstrak: Studi Literatur: Nyeri Kepala Pada Epilepsi. Epilepsi merupakan salah satu gangguan neurologi dengan rata-rata prevalensi 8% di seluruh dunia. Kelainan ini dapat disertai dengan berbagai komorbid salah satunya adalah nyeri kepala. Nyeri kepala dapat ditemukan pada 8-15% populasi epilepsi, dimana kelainan ini bisa terjadi sebelum, saat, atau setelah suatu episode bangkitan, dan bisa juga tidak berkaitan dengan bangkitan. Nyeri kepala pada epilepsi merupakan gejala yang sering sekali tidak terdiagnosis dan tidak diobati karena baik dokter dan pasien akan lebih fokus pada penyakit epilepsi sendiri dibanding nyeri kepalanya. Epilepsi adalah kelainan otak yang ditandai oleh kecenderungan terjadinya bangkitan epileptik dengan konsekuensi neurobiologi, kognitif, psikologi dan sosial. Nyeri kepala preiktal adalah nyeri kepala yang terjadi < 24 jam sebelum terjadinya bangkitan dan berlangsung sampai terjadinya bangkitan. Nyeri kepala iktal adalah nyeri kepala yang terjadi disertai dengan gambaran abnormal pada perekaman EEG. Nyeri kepala pasca iktal adalah nyeri kepala yang terjadi dalam waktu 3 jam setelah terjadinya bangkitan dan hilang spontan 72 jam setelah onset bangkitan. Nyeri kepala interiktal yaitu nyeri kepala yang tidak berkaitan dengan terjadinya bangkitan biasanya terjadi > 24 jam sebelum  dan > 72 jam setelah bangkitan epilepsi. Migrain merupakan nyeri kepala yang banyak ditemukan pada pasien epilepsi. Baik migrain dan epilepsi memiliki patofisiologi yang hampir sama sehingga apabila kelainan ini ditemukan pada epilepsi maka perlu dipertimbangkan pemberian OAE yang juga efektif untuk migrain.
Effects of Euthanasia on Animal Research Maharani, Ni Putu Radela; Fadlyah, Nur Ashfiya; Setyaningrum, Dyah Ayu Woro; Hairunisa, Nany
Veterinary Biomedical and Clinical Journal Vol. 6 No. 1 (2024)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2024.006.01.6

Abstract

The use of experimental animals is widely conducted in the medical field, both for research on the processes of disease occurrence (pathogenesis), the causes of disease (etiology), and research on therapy. Therefore, it is important to understand how euthanasia in experimental animals affects the integrity of the sample and its influence on research results. This article was compiled from several literature sources searched from Google Schoolar and PubMed published within the last 10 years, with keywords such as "code of ethics in experimental animals", "methods of euthanasia in experimental animals", "overdose anesthesia methods in animal euthanasia", "barbiturate injection methods in rats", "inhalation methods in animal euthanasia", "biochemical effects of euthanasia", and "histological effects of euthanasia". This paper discusses euthanasia methods, namely overdose anesthesia, inhalation, and injection. This paper aims to discuss how the method of euthanasia and the choice of drugs can impact the biochemical and histological changes in animals after the euthanasia process. Choosing the right euthanasia method is essential, as the species of animals involved and the research goals are considered. Using methods that align with the biological characteristics and behavior of the animals can help ensure the success of the research while also considering ethical aspects and animal welfare.
Relationship between Emotional Distress and Workplace Influence on Depressive Symptoms among Online Motorcycle Taxi Drivers Merijanti, Lie Tanu; Hairunisa, Nany; Ridwan, Alvin Muhamad; Pusparini, Pusparini; Meiyanti, Meiyanti; Tjahjadi, Muljadi; Isahak, Marzuki bin
Althea Medical Journal Vol 11, No 4 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v11n4.3417

Abstract

Background: The rise of online motorcycle taxi services, driven by the demand for transportation and new technologies, has created a new landscape for drivers. However, despite the benefits, these drivers are not considered employees and are therefore vulnerable to psychosocial risks. This study aimed to investigate the relationship between psychosocial hazards and depressive symptoms among online motorcycle taxi drivers. Methods: A cross-sectional study was conducted, involving 218 online motorcycle taxi drivers in Jakarta, Bogor, Depok, and Tangerang from September to December 2022. The Copenhagen Psychosocial Questionnaire version III was used to assess psychosocial hazards in the workplace and the likelihood of developing depressive symptoms. A multiple linear regression test was used, with a significance level set of p < 0.05.Results: Most respondents were male, and many had worked for over five years, with the majority working more than 8 hours a day. Emotional burden and workplace influences were positively correlated with depressive symptoms (p = 0.017; β = 0.154; and p = 0.002; β = 0.166, respectively). In contrast, the meaning of work and clarity of roles were negatively correlated with depressive symptoms (p = 0.009; β = -0.161; and p = 0.024; β = -0.195, respectively).Conclusion: This study highlights that emotional stress and workplace influence can exacerbate depressive symptoms, while a clear and meaningful work environment have a positive impact. Healthy lifestyle habits are one of the stress management solutions to improve emotional wellness.
DETECTION AND COUNSELING OF OCCUPATIONAL DISEASES IN GREEN MUSSEL PEELERS IN CILINCING, NORTH JAKARTA Amalia, Husnun; Hairunisa, Nany; Mashabi, Yasmine; Zaina, Nashita Amira
Jurnal Pengabdian Masyarakat Trimedika Vol. 2 No. 1 (2025)
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/abdimastrimedika.v2i1.22151

Abstract

Latar Belakang Indonesia adalah negara kepulauan terbesar di dunia dan masalah kesehatan mata masih menjadi sesuatu yang belum dapat diselesaikan arena sirtuasi geografis dan demografis. Terdapat 0,4% angka kebutaan pada penduduknya, dan 80% adalah kebutaan yang dapat dicegah atau diobati dan refraksi adalah menjadi penyebab utama (42%). Kelainan refraksi sampai saat ini masih menjadi tantangan kesehatan masyarakat karena menjadi penyebab gangguan penglihatan yang paling besar dan mengenai seluruh kelompok usia dan percepatan terjadinya gangguan penglihatan pada berusia produktif akan merugikan perekonomian negara karena terganggunya sumber daya manusia. Fakultas Kedokteran Universitas Trisakti dan masyarakat dapat membantu berpartisipasi pada program ini dengan melaksanakan pengabdian skrining Kesehatan mata dan memberikan tatalaksananya agar mencegah kebutaan akibat kelainan refraksi khususnya. Metode Kegiatan pengabdian diikuti oleh 136 peserta, dilakukan anamnesis, pemeriksaan Kesehatan mata termasuk pemeriksaan refraksi. Bagi peserta yang memerlukan kacamata dilakukan edukasi dan diberikan kacamata. Hasil Peserta berusia anatara 3 tahun sampai 71 tahun, dengan 83,1% adalah laki-laki dan 16,9% adalah perempuan dan Sebagian besar peserta tidak memiliki pekerjaan (41,9%). Sekitar 42,6% memiliki Riwayat pengguna kacamata namun yang membutuhkan kacamata adalah 52,2% peserta. Kesimpulan Pada 136 penduduk kurang mampu di Pondok Aren, 57,4% memerlukan kacamata untuk memperbaiki penglihatannya.
DETEKSI DAN PENYULUHAN PENYAKIT AKIBAT KERJA PADA PENGUPAS KERANG HIJAU DI CILINCING, JAKARTA UTARA Amalia, Husnun; Hairunisa, Nany; Mashabi, Yasmine; Zaina, Nashita Amira
Jurnal Abdi Masyarakat Indonesia (JAMIN) Vol 6 No 2 (2024): JURNAL ABDI MASYARAKAT INDONESIA (JAMIN)
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jamin.v6i2.17861

Abstract

DKI Jakarta is the most populous city in Indonesia and 59.29% of North Jakarta's population are fishermen, and Cilincing is the largest producer of green mussels in DKI Jakarta with 286 green mussel fishermen (2010), which is 70% of the total number of green mussel fishermen of DKI Jakarta and involves around 1,200 workers. The professions of the community are fishermen and clam collectors (25%), shellfish peel workers (8%), and shellfish traders (6%). The profession of shelling shells is carried out less ergonomically for 6-8 hours a day. This can lead to occupational diseases including Low Back Pain, Frozen shoulder, trigger finger, and the threat of chemical hazards. This service activity aims to detect occupational diseases in green mussel peeling workers and provide preventive information so that the disease does not occur. The consultation and examination activities were attended by 87 residents, aged from 5-84 years. Occupational diseases are mainly found in residents who are still actively working in the Green mussel peeling industry. Occupational diseases are found to be fit for duty in this industry. The lifting officer seemed to lift less ergonomic activities so that abnormalities of Hernia Nucleus Purposus (HNP), myalgia Shoulder pain, and Low Back Pain (LBP) were detected. Scallop peelers complain of low back pain (LBP), neck pain, and Carpal Tunnel Syndrome (CTS). Counseling participants are women working as green mussel peelers aged 20-73. The duration of working hours per day > 5 hours (92.3%). Education level is low (76.9%) and length of work experience varies between 1->30 years. Counseling showed good results, judging from the post-test scores 100% of participants showed good results. Workers need follow-up from various parties to prevent occupational diseases in green mussel peeling workers.
EDUKASI PERSONAL HYGIENE PADA PEKERJA PENANGANAN PRASARANA DAN SARANA UMUM (PPSU) Lestari, Ade Dwi; Ridwan, Alvin Mohamad; Hairunisa, Nany; Khairani, Rita; Khairunisa, Adinda; Kencana, Gita; Iskandar, Dian
Jurnal Pengabdian Masyarakat Trimedika Vol. 2 No. 2 (2025)
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/abdimastrimedika.v2i2.22920

Abstract

Personal hygiene is a crucial component of occupational health, particularly for sanitation workers, including Public Infrastructure and Facility Handling (PPSU) workers in Rawa Buaya Village. This community service project aimed to provide education and assess the knowledge and awareness of PPSU workers regarding personal hygiene, with a focus on handwashing. The activity included counseling sessions, pre- and post-tests, and the distribution of educational materials such as posters and presentations. The results showed a significant improvement in workers' knowledge, with an average post-test score increase of 37.68%. These findings highlight the importance of continuous occupational health education to enhance hygiene practices and reduce health risks among PPSU workers
Survei Pola Kuantitas Peresepan Antibiotik di Tiga Rumah Sakit di Indonesia dengan Penatagunaan Antimikroba Digital Natadidjaja, Ronald Irwanto; Lekok, Widyawati; Ariyani, Aziza; Adlani, Hadianti; Adianto, Raymond; Maharani, Ronaningtyas; Sumarsono, Hadi; Yenny, Yenny; Samira, Jihan; Hairunisa, Nany; Amalia, Husnun; Faradila, Meutia Atika; Fadilah, Tubagus Ferdi; Kalumpiu, Joice Viladelvia; Yuliana, Yuliana; Mulyani, Sri; Anggiat, Desi; Marja, Triyoko Septio; Pertiwi, Iin Indra; Dianawati, Dianawati; Legoh, Grace Nerry; Rantung, Alvin Lekonardo
Jurnal Biomedika dan Kesehatan Vol 8 No 2 (2025)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background Antimicrobial Stewardship Program (ASP) is very essential. There are three categories of antimicrobial agents as recommended by WHO: Access, Watch and Reserve. e-RASPRO, a digital ASP model, may alter antibiotic prescribing patterns by prioritizing Access category antibiotic prescribing. Methods Our manuscript presented a quantitative survey on antibiotic prescribing patterns within 3 months and 9 months before and after implementing digital electronic-RASPRO (e-RASPRO) in three Indonesian hospitals, utilizing retrospective inpatient data. This analysis included the appropriateness of empirical antibiotic prescribing and the quantity of antibiotic prescribing based on each category. Results In the first 3 months, we found that 90.16%, 83.98%, and 81.15% of patients were included in Type 1 Risk Stratification. The appropriateness of initial empirical antibiotic prescribing with the digital guideline on antimicrobial use of e-RASPRO in three hospitals was 81.59%, 76.09% and 24.48%, respectively. Within 9 months after implementing e-RASPRO in Hospital A and B and within 3 months in Hospital C, there was a trend of reduced quantity of Watch category antibiotic prescribing of 54.93% (-58.86% per inpatient), 21.11% (-9.97% per inpatient), and 8.59% (-4.15% per inpatient), respectively. There was a 12.42% (+2.61 % per inpatient) and 223.17% (+268.83% per inpatient) increase in the quantity of Access category antibiotic prescribing in Hospitals A and B, while in Hospital C, the quantity decreased by 6.81% (-2.29% per inpatient).   Conclusions There are changes in antibiotic prescribing patterns, particularly in the antibiotics included in the Watch and Access categories following the implementation of e-RASPRO. The relationship between digital antimicrobial stewardship use and the results still needs further research.
Deteksi gen secara Epidemiologi Molekuler pada Isolat Klinik Klebsiella pneumoniae dari Pasien Dewasa dengan komorbid di Rumah Sakit Baghdad Kudaer, Nuha B; Risan, Mohsen Hashim; Raheem, Rasha; Zainulabdeen, Khalid; Salman, Israa; Hairunisa, Nany; Amalia, Husnun; Hameed, Seenar; Yousif, Emad
Jurnal Biomedika dan Kesehatan Vol 6 No 2 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.196-215

Abstract

Background Klebsiella species is one of the most worldwide opportunistic pathogens in the world that cause infections at multiple sites like lung, urinary tract, bloodstream, wound or surgical site, and brain. Klebsiella pneumoniae has many types of virulence factors that give the bacteria the ability to invade the host and cause infections. Methods A total of (105) human clinical samples were collected from different patients with different cases. Klebsiella pneumonia were isolated from 30 samples. The bacteria were identified by biochemical tests and certified by using VITEK 2 system and genetically by amplify using PCR for 16 rRNA gene. One of the Klebsiella pneumoniae virulence factors is the capsule that is responsible for the macrophage resistance and its also responsible for serotype. So to confirm the strains isolated, PCR Gene detection of, MagA, K2A, RmpA, and Kfu, where (magA, k2A, rmpA, kfu) gens are responsible for capsule synthesis of Klebsiella pneumonia have been done. Results There were 30 strains of Klebsiella pneumoniae were identified. Epidemiological studies show that infections are preceded by gastrointestinal colonization, with the gastrointestinal tract being the most important reservoir for transmission. The primary bacterial isolates were identified based on their cultural, microscopic, and biochemical traits. The API system (API 20E) and VITEK 2 systems were used to confirm the identity of the bacterial isolates. Colony morphology revealed that Klebsiella pneumonia was Gram-negative, non-motile, microscopic straight rods grouped singly or in pairs. Biochemical tests showed that neutral end products prevailed over acidic end products, with Klebsiella producing negative results for indole. The Kligler Iron Agar (KIA) test showed that Klebsiella isolates changed the color of the slant and butt, producing an acidic slant and acid butt, along with gas production. The urease test for Klebsiella distinguishes between Enterobacter and Klebsiella isolates, as Klebsiella can manufacture the urease enzyme. The indole test distinguishes K. pneumonia from K. pneumonia from K. mobiliz. The API 20E system was used for biochemical testing, and the VITEK 2 system was used for identification. The VITEK 2 system was used to test for biochemical and antibiotic susceptibility, and the results supported the findings from morphological and biochemical analyses. PCR amplification was used for molecular detection, and all nine isolates tested positive for the magA and k2A genes. The ferric iron uptake system gene (kfu) and the extracapsular polysaccharide synthesis regulator gene (rmpA) were amplified using specific primer pairs. The VITEK 2 system demonstrated promising outcomes for K. pneumoniae identification. However, standard diagnostic methods are costly and time-consuming. Conclusions Navigating the complex landscape of infectious diseases, collaborative research projects have become indispensable in unraveling the mysteries surrounding pathogens. The project in Baghdad, having stood as a shining example of such collaboration, provided valuable insights into the identification, characterization, and molecular aspects of Klebsiella pneumoniae strains. The findings, have not only contributed to the scientific community's understanding of bacterial infections but also paved the way for enhanced strategies in diagnosis and treatment.
Studi Faktor-Faktor yang Berhubungan dengan HIV pada Perempuan di Kalimantan Barat, Indonesia Hairunisa, Nany; Sabrina, Isra; Amalia, Husnun; Mashabi, Yasmine; Zaina, Nashita Amira; Yousif, Emad
Jurnal Biomedika dan Kesehatan Vol 6 No 1 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.89-107

Abstract

Background According to national data, West Kalimantan is one of the ten top provinces that reported AIDS cases, ranked eighth. Until December 2019, based on data recorded in the Provincial Health Office that reported to the Indonesia Ministry of Health, the AIDS case rate in West Kalimantan was 49.35, showing over the national AIDS case rate (38.93). In this study, an unmatched case-control determines the factors associated with HIV/AIDS among women in West Kalimantan, Indonesia. Methods The study was conducted among 90 women who tested positive for HIV/AIDS (cases) and 90 who tested negative for HIV/AIDS (controls). Data were collected using questionnaires from June 2019 to August 2019 at three community health centres in West Kalimantan. Data were analyzed using IBM Statistical Package Social Science (SPSS) 19. Descriptive analyses and Multivariate logistic regression analysis were used to examine the factors associated with HIV/AIDS. Results: This study has found a significant association between crucial aspects such as marital status, occupation, knowledge about HIV/AIDS, HIV treatment, and VCT (Voluntary Counseling and Testing) service program with cases of HIV/AIDS. A significant association between marital statuses with HIV/AIDS suggests that divorced/widowed have a higher risk of having HIV/AIDS, followed by the married group. Women with good educational backgrounds will likely know how to prevent HIV infection and take preventive measures to protect themselves. Results This study found a significant relationship between several important aspects such as marital status, occupation, knowledge of HIV/AIDS, HIV treatment, and the VCT (Voluntary Counseling and Testing) service program with HIV/AIDS cases. The significant relationship between marital status and HIV/AIDS shows that divorced/widows have a higher risk of contracting HIV/AIDS, followed by the married group. Women with a good educational background tend to know about HIV infection prevention measures and take precautions to protect themselves. Conclusions Some factors are significantly related to HIV/AIDS. Thus, educating women about sex could potentially decrease the number of HIV/AIDS cases.
Studi Banding tentang pengembangan vaksin untuk COVID-19 Alsayed, Raghda; Zainulabdeen, Khalid; Salman, Israa; Hairunisa, Nany; Amalia, Husnun; Yusop, Rahimi M; Redwan, Amamer M; Yousif, Emad
Jurnal Biomedika dan Kesehatan Vol 6 No 1 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.127-132

Abstract

The human respiratory system can be infected with coronaviruses (CoVs), one of the families of viruses that can lead to symptoms ranging from mild to fatal. Seven genera of CVS have been identified as having human infection to date. The virus can spread as fine, liquid particles from the mouth or nose of an infected person when coughing, sneezing, speaking, or breathing. The diameter of droplet particles ranges from large to small. In this review, we summarize vaccine development for COVID-19. We anticipate this study will be a valuable resource for any researcher interested in creating a COVID-19 vaccine.
Co-Authors Abikusno, Revalita Adhiwardan, Anggraeni Adianto, Raymond Adlani, Hadianti Agil, Nadifa Ahmed, Dina Alsayed, Raghda Anastasya, Karina Shari Anggiat, Desi Ariyani, Aziza Astien, Astien Aswar, Andini Briliant, Permaisonya David Tjahyadi dianawati, dianawati Djebli, Noureddine Dwi Lestari, Ade Erlani Kartadinata, Erlani Fadlyah, Nur Ashfiya Faradila, Meutia Atika Gerie Amarendra Grace Nerry Legoh Hadi Sumarsono Hameed, Seenar Hari Krismanuel Hosea Jaya Edy Husain, Amani Husnun Amalia Isahak, Marzuki bin Iskandar, Dian Joice Viladelvia Kalumpiu, Joice Viladelvia Kadhom, Mohammed Kencana, Gita Khairunisa, Adinda Kudaer, Nuha B Larasari, Andira LEKOK, WIDYAWATI Lestari, Ade Dwi Lie Tanu Merijanti, Lie Tanu Liman, Patricia Budihartanti Magdalena Wartono Maharani, Ni Putu Radela Maharani, Ronaningtyas Mahdi, Sarah Marja, Triyoko Septio Mashabi, Yasmine Meiyanti Meiyanti, Meiyanti Mohamad Ridwan, Alvin Natadidjaja, Ronald Irwanto Nugroho Abikusno Oladimeji, Ashaolu Victoria Parwanto, Edy Pertiwi, Iin Indra Prasetyaningsih, Noviani Primandari, Rima Anindita Purnamawati Tjhin, Purnamawati Pusparini Pusparini Raheem, Rasha Rantung, Alvin Lekonardo Redwan, Amamer M Ridwan, Alvin Mohamad Ridwan, Alvin Muhamad Risan, Mohsen Hashim Rita Khairani, Rita Sabrina, Isra Salman, Israa Samira, Jihan Setyaningrum, Dyah Ayu Woro Sri Mulyani Sudarma, Verawati T, Febrina Thamer, Hamsa Tjahjadi, Muljadi Tjam Diana Samara Tubagus Ferdi Fadilah, Tubagus Ferdi Wawan Kurniawan Witjaksana, Riani YENNY YENNY Yousif, Emad Yuliana Yuliana Yusop, Rahimi M Zaina, Nashita Amira Zainulabdeen, Khalid