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Prabowo, Nurhasan Agung
Fakultas Kedokteran, Universitas Sebelas Maret, Surakarta Dan RS Universitas Sebelas Maret
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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TINGKAT EFEKTIVITAS DETEKSI MANDIRI HIPERTENSI OLEH KOMUNITAS DI PUSKESMAS GAJAHAN Myrtha, Risalina; Ardyanto, Tonang Dwi; Prabowo, Nurhasan Agung; Apriningsih , Hendrastutik; Dyanneza, Frieska; Kuncorowati, Niken Dyah Aryani; Nugroho, Novianto Adi; Suwandono, Adji; Sari, Maria Galuh Kamenyangan; Shofiyah, Laily
Sebatik Vol. 28 No. 1 (2024): June 2024
Publisher : STMIK Widya Cipta Dharma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46984/sebatik.v28i1.2323

Abstract

Pengabdian ini bertujuan untuk menguatkan peran komunitas dalam kemandirian kesehatan melalui deteksi mandiri hipertensi dan kelainan irama jantung di Puskesmas Gajahan. Peningkatan prevalensi penyakit tidak menular, khususnya hipertensi dan fibrilasi atrium, memerlukan intervensi berbasis komunitas yang efektif untuk mengurangi beban penyakit ini. Metode pengabdian ini melibatkan pada kader kesehatan di wilayah kerja Puskesmas Gajahan dengan melakukan edukasi dan pelatihan kepada kader puskesmas Gajahan mengenai cara deteksi mandiri hipertensi dan kelainan irama jantung. Pelatihan ini mencakup cara pengukuran tekanan darah mandiri dan cara deteksi mandiri kelainan irama jantung dengan cara meraba nadi sendiri (MENARI), serta edukasi mengenai faktor risiko dan tanda-tanda kedua penyakit ini. Hasil dari implementasi pelatihan ini menunjukkan peningkatan pengetahuan dan keterampilan masyarakat dalam mendeteksi dini hipertensi dan kelainan irama jantung. Partisipan yang mengikuti pelatihan mampu melakukan pemeriksaan tekanan darah dan deteksi kelainan irama jantung secara mandiri dengan benar. Selain itu, terdapat peningkatan kesadaran masyarakat tentang pentingnya pemeriksaan kesehatan rutin dan perubahan gaya hidup untuk mengurangi risiko penyakit tidak menular. Kesimpulannya, penguatan peran komunitas melalui edukasi dan pelatihan deteksi mandiri terbukti efektif dalam meningkatkan kemandirian kesehatan masyarakat di wilayah kerja Puskesmas Gajahan.
Correlation of Interleukin-6 Level with Neutrophil to Lymphocyte Ratio and Disease Severity in COVID-19 Patients Apriningsih, Hendrastutik; Prabowo, Nurhasan Agung; Reviono, Reviono; Anindita, Brigitta Devi; Myrtha, Risalina; Putri, Desy Puspa; Hermawati, Berty Denny
Global Medical & Health Communication (GMHC) Vol 11, No 1 (2023)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v11i1.9643

Abstract

Coronavirus disease 2019 (COVID-19) causes severe acute respiratory disease in humans and has spread rapidly worldwide since its first identification in December 2019. The neutrophil-to-lymphocyte ratio (NLR) describes the balance between the severity of inflammation and the immune system to be used as an important systemic inflammatory marker. Rapid progression of clinical deterioration is characterized by severe respiratory symptoms related to high levels of pro-inflammatory cytokines, like interleukin-6 (IL-6), indicating that the occurrence of cytokine storms leads to increased mortality. This study aims to assess the correlation between IL-6 and NLR in predicting the severity of COVID-19. This prospective cohort study was conducted at the COVID-19 ward of Universitas Sebelas Maret Hospital in August–September 2021. This study involved 66 COVID-19 patients >18 years old with asymptomatic to critical degree and Charlson Comorbidity Index (CCI) value ≤3. Examination of laboratory parameters and serum IL-6 was carried out when the patient entered the Emergency Room. Statistical test with Pearson’s correlation test, significant if p<0.05. There is no significant correlation between IL-6 and NLR with p=0.56 and r=0.08, and a strong correlation between IL-6 and disease severity with p=0.000 and r=0.454. The conclusion is that IL-6 does not correlate with NLR and strongly correlates with disease severity in COVID-19 patients.
Thrombosis of the inferior vena cava and acute kidney injury in dengue shock syndrome: A rare case with unique nursing challenges Prabowo, Nurhasan Agung; Sari, Yulia; Putri, Desy Puspa; Habibah, Sopia Nur; Rachmah, Azkia; Hartono, Hartono
Jurnal Keperawatan Padjadjaran Vol. 12 No. 3 (2024): Jurnal Keperawatan Padjadjaran
Publisher : Faculty of Nursing Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkp.v12i3.2641

Abstract

Background: Dengue Shock Syndrome (DSS) is a severe complication of dengue fever that can lead to life-threatening conditions such as thrombosis and acute kidney injury (AKI). These rare complications highlight the importance of early recognition and multidisciplinary management to improve clinical outcomes. Purpose: This case study aims to report and discuss the clinical management and outcomes of a patient with DSS complicated by inferior vena cava thrombosis and AKI, focusing on nursing interventions and therapeutic strategies. Methods: This manuscript reports a case by utilizing the patient’s baseline data, clinical progression, and treatment outcomes. A middle-aged male patient presented to the emergency department with high fever, shock, and signs of plasma leakage. Laboratory and imaging findings confirmed DSS with AKI and inferior vena cava thrombosis. The patient received fluid resuscitation, inotropic support, anticoagulation therapy, and multidisciplinary care, including close nursing monitoring. Results: After seven days of hospitalization, the patient showed significant improvement, with resolution of shock, normalization of platelet count, and recovery of renal function. Comprehensive nursing care, including vital sign monitoring, medication management, and patient education, played a pivotal role in the recovery process. At a follow-up visit on day 12, the patient demonstrated full recovery with no complications. Conclusions: This case highlights the importance of early diagnosis and a multidisciplinary approach, including cautious anticoagulation therapy, to effectively manage DSS with thrombosis and AKI. Integrating nursing interventions and strict monitoring were crucial to achieving positive clinical outcomes. This report provides valuable insights into managing similar cases in endemic areas.
Association of Family History, Body Mass Index, and Exercise Regularity with HbA1c Status in Type 2 Diabetes Melitus Patients Aisyah, Riandini; Prabowo, Nurhasan Agung
MAGNA MEDIKA Berkala Ilmiah Kedokteran dan Kesehatan Vol 12, No 1 (2025): FEBRUARY
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.12.1.2025.1-8

Abstract

Background:  Urban life, especially in Surakarta, is easy to access and full of high-carbohydrate food and drink. This has increased unhealthy behavior and diets. The prevalence of diabetes Mellitus (DM) in Surakarta is growing, reaching 24% in 2021. Physical exercise and poor diet are important risk factors for DM, coupled with genetics, causing obesity. HbA1c levels periodically assess DM patients' glycemic management.Objective: This study aims to determine the association between family history, body mass index, and regular exercise with HbA1c status in type 2 DM patients at UNS Surakarta Hospital.Methods: The research was an observational study; 24 patients diagnosed with type 2 DM were recruited from the outpatient clinic of Universitas Sebelas Maret Hospital, Surakarta, Indonesia, in October 2021. Measurements were conducted to determine their HbA1c level by enzymatic methods and body mass index by measuring body weight and height, and they were questioned regarding their physical exercise and family history of diabetes. The data collected were analyzed using multiple logistic regression to ascertain the association between family history, body mass index, and exercise regularity with HbA1c status.Results: The findings indicated no statistically significant association between genetic background, body mass index, and exercise frequency with HbA1c status (p>0.05).Conclusion: This research shows that genetic history, body mass index, and exercise regularity are not associated with HbA1c status in type 2 DM in included subjects.
PELATIHAN ELEKTROKARDIOGRAFI BAGI PERAWAT Prabowo, Nurhasan Agung; Ardyanto, Tonang Dwi; Apriningsih, Hendrastutik; Myrtha, Risalina
Jurnal Dharma Bhakti Ekuitas Vol. 6 No. 2 (2022): Jurnal Dharma Bhakti Ekuitas
Publisher : Universitas Ekuitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52250/p3m.v6i2.419

Abstract

Kejadian gawat daruat bisa terjadi pada siapa saja, kapan saja dan dimana saja. Keadaan ini menuntut kesiapan para tenaga kesehatan untuk melakukan tindakan sesuai dengan kompetensinya. Salah satu profesi kesehatan yang bertanggung jawab dalam penatalaksaan pasien gawat darurat adalah perawat. Penelitian di medan tahun 2019 menyebutkan mayoritas perawat tidak memahami cara membaca rekam jantung yang baik. Setelah berkoordinasi dengan ketua PPNI Rumah Sakit Universitas Sebelas Maret, permasalahan utama yang dialami PPNI adalah Pengetahuan mengenai cara membaca EKG pada perawat masih terbatas. Perawat tidak mengetahui gambaran rekam jantung yang berbahaya. Pelatihan membaca rekam jantung jarang ditemui di era pandemic COVID-19, dan tidak ada buku panduan khusus untuk membaca rekam jantung bagi perawat. Tahap-tahap pengabdian dilakukan dengan mengadakan workshop pelatihan membaca EKG secara daring pada minggu ketiga bulan April 2021.Tahap pengabdian selanjutnya adalah buku petunjuk EKG dan brosur EKG. Terjadi peningkatan pengetahuan perawat terhadap EKG dengan peningkatan nilai pretes 55,5 menjadi 72,5. Pelatihan EKG bagi perawat meningkatkan pengetahuan perawat sehingga meningkatkan kualitas pelayanan Kesehatan.
Role of Gamma-Glutamyl Transferase, High Sensitivity C Reactive Protein and Apolipoprotein B as A Marker of Disease Severity in Psoriasis Shofiyah, Laily; Ardyanto, Tonang Dwi; Prabowo, Nurhasan Agung; Aprilningsih, Hendrastutik; Myrtha, Risalina; Kuncorowati, Niken Dyah Aryani; Suwandono, Adji; Nugroho, Novianto Adi; Sari, Maria Galuh Kamenyangan; Dyanneza, Frieska
Gema Lingkungan Kesehatan Vol. 23 No. 3 (2025): Gema Lingkungan Kesehatan
Publisher : Poltekkes Kemenkes Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36568/gelinkes.v23i3.285

Abstract

Psoriasis can develop into systemic psoriasis, which primarily affects the liver, bile ducts, and cardiovascular system. Assessing the severity of psoriasis was crucial for determining treatment and cardiovascular disease risk. The aim of this study was to determine the role of Gamma-Glutamyl Transferase (GGT), High Sensitivity C-Reactive Protein (HS-CRP), and apolipoprotein B (APO B) in assessing the severity of psoriasis. Methods: This study was a cross-sectional, observational analytic study. A total of 33 psoriasis patients were tested for GGT, HS-CRP, APO B levels, and the Psoriasis Area and Severity Index (PASI) score. Results: The average GGT level was 70.75±56.47 u/L, the average HS-CRP level was 0.91±1.03 mg/L, the average APO B level was 110.09±26.47 mg/dL, and the average PASI score was 11.70±4.54. 12.1% of patients had mild psoriasis, 51.5% had moderate psoriasis, and 36.4% had severe psoriasis. There was a positive and strong correlation between GGT and PASI score, HS-CRP and PASI score, and APO B and PASI score. The multivariate correlation between GGT, HS-CRP, and APO B with PASI score had a value of R = 0.874, F = 31.145, p = <0.001. Conclusion: The multivariate correlation between GGT, HS-CRP, and APO B with PASI scores shows a positive and strong correlation, thus it useful for assessing the severity of psoriasis and evaluating the likelihood of cardiovascular disease.
Implementation of an Education and Early Detection Program to Reduce the Risk of Occupational Lung Disease in Furniture Craftsmen in Sambirembe Village Ardyanto, Tonang Dwi; Myrtha, Risalina; Prabowo, Nurhasan Agung; Apriningsih , Hendrastutik; Dyanneza, Frieska; Kuncorowati, Niken Dyah Aryani; Nugroho, Novianto Adi; Suwandono, Adji; Sari, Maria Galuh Kamenyangan; Shofiyah, Laily
Sebatik Vol. 29 No. 2 (2025): December 2025
Publisher : STMIK Widya Cipta Dharma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46984/sebatik.v29i2.2640

Abstract

Furniture industry workers in Sambirembe Village, Sragen, face significant health risks from exposure to wood dust, particularly an increased risk of Chronic Obstructive Pulmonary Disease (COPD). This research is prompted by the low awareness among workers regarding these risks and the minimal use of personal protective equipment (PPE). The objective of this program was to increase workers' and business owners' knowledge of lung health, promote early detection of COPD, and encourage the adoption of safer work practices. The method employed was an intervention that included health education and lung function screening via questionnaires and spirometry. The results revealed a critical knowledge gap, where over 85% of workers had never heard of COPD, even though 70% of them reported experiencing respiratory symptoms. Furthermore, over 90% of workers admitted to rarely using masks. The intervention, which combined education with personalized spirometry data feedback, proved effective in increasing worker awareness of tangible health risks. In conclusion, the education-based and health-screening intervention program successfully raised furniture workers' understanding of COPD risks. An approach that integrates information with personal medical evidence is crucial for promoting behavioural change in high-risk work environments.
The Importance of Hyperthyroid Screening in Acute Decompensated Heart Failure with Persistent Tachycardia Despite Optimal Decongestion: A Case Report Myrtha, Risalina; Wijayanto, Matthew Aldo; Prabowo, Nurhasan Agung
Jurnal Kardiologi Indonesia Vol 46 No 4 (2025): October - December, 2025
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.2006

Abstract

In “The Importance of Hyperthyroid Screening in Acute Decompensated Heart Failure with Persistent Tachycardia Despite Optimal Decongestion: A Case Report” (Indonesian Journal of Cardiology, 43(3), 123-9. https://doi.org/10.30701/ijc.1328), there is an error noted. An error has been found in the PDF version of this article. The DOI printed in the PDF is incorrect. The correct DOI is https://doi.org/10.30701/ijc.1328. The error occurs only in the PDF; the DOI listed in the article metadata is already correct.The publisher apologizes for any inconvenience caused by this error.DOI of original article: https://doi.org/10.30701/ijc.1328
Umbilical Cord Mesenchymal Stem Cells Secretome in Osteoarthritis Patients: A Case Report Nurudhin, Arief; Prabowo, Nurhasan Agung; Wedhiningsih, Yulyani; Sunarso, Indrayana
Gema Lingkungan Kesehatan Vol. 23 No. 4 (2025): Gema Lingkungan Kesehatan
Publisher : Poltekkes Kemenkes Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36568/

Abstract

We report a case study of a 58-year-old lady diagnosed with symptomatic knee osteoarthritis (OA) who received umbilical cord-derived mesenchymal stem cell (UC-MSC) secretome via intra-articular injections once weekly for a total of five weeks. This treatment significantly reduced pain compared to the control, using a Visual Analog Scale, with pain scores reducing from 7/10 to 3/10. Moreover, the patient showed marked functional capacity improvement, as indicated by a Western Ontario and McMaster Universities Osteoarthritis Index score from 65 to 30. Her Kellgren-Lawrence grade also improved radiographically from 4 to 2 indicating either an initiation of cartilage regeneration or a reduction in degenerative change. These favorable results position the UC-MSC secretome as a novel and safe treatment for knee osteoarthritis, making it a potent non-invasive replacement therapy to classical treatments. The researchers advise that these findings must be confirmed in bigger, controlled trials before the therapeutic effects of UC-MSC secretome can be established in broader patient populations.
Association Between Glycated Hemoglobin (HbA1c) Levels and Mean Platelet Volume (MPV) in Patients with Type 2 Diabetes Mellitus Utami, Aloysia Flower Lula; Prabowo, Nurhasan Agung; Hermawati, Berty Denny; Putri, Desy Puspa; Argaheni, Niken Bayu
JURNAL INFO KESEHATAN Vol 24 No 1 (2026): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol24.Iss1.2334

Abstract

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia, which can trigger inflammatory responses contributing to various vascular complications. Inflammation plays a key role in the pathogenesis of DM-related complications through mechanisms involving oxidative stress and activation of NF-κB signaling, which influence platelet production and activity. Given inconsistent findings regarding the association between HbA1c and mean platelet volume (MPV) in previous studies, this study aims to investigate the relationship between HbA1c and MPV, a pro-thrombotic and inflammatory marker, in patients with type 2 diabetes mellitus. This study is an analytical observational study with a cross-sectional approach. Data were collected from the medical records of Universitas Sebelas Maret (UNS) Hospital, Indonesia, using purposive sampling. HbA1c and MPV data were obtained from patients’ medical records over the past year. Statistical analysis was performed using the Shapiro–Wilk normality test and Pearson correlation test. A total of 38 samples were included in the study. The mean HbA1c level was 10.37% (range: 6.50–16.10), while the mean MPV was 9.38 fL (range: 7.30–12.50). Pearson correlation test showed a significant relationship between HbA1c and MPV (r = 0.467; p = 0.003). There is a significant positive correlation between HbA1c and MPV in patients with type 2 diabetes mellitus.      
Co-Authors Adji Suwandono Adji Suwandono Andri Haryanto Anindita, Brigitta Devi Aprilningsih, Hendrastutik Apriningsih, Apriningsih Apriningsih Apriningsih, Hendrastutik Argaheni, Niken Bayu Arief Nurudhin Arief Nurudhin Arief Nurudhin Arief Nurudhin Arief Nurudhin Arief Nurudhin Arifin Arifin Aryani, Niken Dyah Asih Anggraeni Astri Tantri Indriani Astri Tantri Indriani Astri Tantri Indriani Berty Denny Hermawati Bryan Arief Aji Rudita Coana Sukma Gautama Desy Puspa Putri Dyanneza, Frieaska Dyanneza, Frieska Evi Nurhayatun Evi Nurhayatun Fahmiati, Cahyani Fatichati Budiningsih Frieska Dyanneza Frieska Dyanneza Frieska Dyanneza Habibah, Sopia Nur Hafi Nurinasari Hapsari, Brigitta Devi Anindita Hartono Hartono Hendrastutik Apriningsih Hendrastutik Apriningsih Hendrastutik Apriningsih Hendrastutik Apriningsih Hermawati, Berty Denny Indriani, Astri Tantri Kuncorowati, Niken Dwi Aryani Kuncorowati, Niken Dyah Aryani Laily Shofiyah Laily Shofiyah Landiasari, Debby Andina Maria Galuh Kamenyangan Maria Galuh Kamenyangan Sari, Maria Galuh Kamenyangan Meirina Mulia Wardani Mirshanti, Farahdila Muchtar Hanafi Myrtha, Risalina Niken Dwi Aryani Kuncorowati Niken Dyah Aryani Kuncorowati Niken Dyah Aryani Kuncorowati Novianto Adi Nugroho Nugroho, Novianto Adi Putri, Desy Puspa Rachmah, Azkia Ratih Puspita Febrinasari Reviono Reviono Riandini Aisyah Risalina Myrtha Risalina Myrtha Risalina Myrtha Risalina Myrtha Shofiyah, Laily Siregar, Sihsusetyaningtyas Tiominar Sri Sulistyowati Sunarso, Indrayana Syahrini Wisdayanti Tamaulina Br Sembiring Tonang Dwi Ardyanto Utami, Aloysia Flower Lula Wedhiningsih, Yulyani Werdiningsih, Yulyani Wijayanto, Matthew Aldo Yeni Farida Yulyani Werdiningsih Yulyani Werdiningsih Yulyani Werdiningsih Yunita . Zainal Arifin Adnan Zainal Arifin Adnan