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All Journal Global Medical and Health Communication WARTA Jurnal Keperawatan Padjadjaran Smart Medical Journal Syntax Literate: Jurnal Ilmiah Indonesia Indonesian Journal of Rheumatology Indonesian Journal of Cardiology Sebatik MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan Logista: Jurnal Ilmiah Pengabdian Kepada Masyarakat Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Dharma Bhakti Ekuitas Smart Society Empowerment Journal Gema Lingkungan Kesehatan
Prabowo, Nurhasan Agung
Fakultas Kedokteran, Universitas Sebelas Maret, Surakarta Dan RS Universitas Sebelas Maret
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Role of Gamma-Glutamyl Transferase, High Sensitivity C Reactive Protein and Apolipoprotein B as A Marker of Disease Severity in Psoriasis Shofiyah, Laily; Ardyanto, Tonang Dwi; Prabowo, Nurhasan Agung; Aprilningsih, Hendrastutik; Myrtha, Risalina; Kuncorowati, Niken Dyah Aryani; Suwandono, Adji; Nugroho, Novianto Adi; Sari, Maria Galuh Kamenyangan; Dyanneza, Frieska
Gema Lingkungan Kesehatan Vol. 23 No. 3 (2025): Gema Lingkungan Kesehatan
Publisher : Poltekkes Kemenkes Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36568/gelinkes.v23i3.285

Abstract

Psoriasis can develop into systemic psoriasis, which primarily affects the liver, bile ducts, and cardiovascular system. Assessing the severity of psoriasis was crucial for determining treatment and cardiovascular disease risk. The aim of this study was to determine the role of Gamma-Glutamyl Transferase (GGT), High Sensitivity C-Reactive Protein (HS-CRP), and apolipoprotein B (APO B) in assessing the severity of psoriasis. Methods: This study was a cross-sectional, observational analytic study. A total of 33 psoriasis patients were tested for GGT, HS-CRP, APO B levels, and the Psoriasis Area and Severity Index (PASI) score. Results: The average GGT level was 70.75±56.47 u/L, the average HS-CRP level was 0.91±1.03 mg/L, the average APO B level was 110.09±26.47 mg/dL, and the average PASI score was 11.70±4.54. 12.1% of patients had mild psoriasis, 51.5% had moderate psoriasis, and 36.4% had severe psoriasis. There was a positive and strong correlation between GGT and PASI score, HS-CRP and PASI score, and APO B and PASI score. The multivariate correlation between GGT, HS-CRP, and APO B with PASI score had a value of R = 0.874, F = 31.145, p = <0.001. Conclusion: The multivariate correlation between GGT, HS-CRP, and APO B with PASI scores shows a positive and strong correlation, thus it useful for assessing the severity of psoriasis and evaluating the likelihood of cardiovascular disease.
Implementation of an Education and Early Detection Program to Reduce the Risk of Occupational Lung Disease in Furniture Craftsmen in Sambirembe Village Ardyanto, Tonang Dwi; Myrtha, Risalina; Prabowo, Nurhasan Agung; Apriningsih , Hendrastutik; Dyanneza, Frieska; Kuncorowati, Niken Dyah Aryani; Nugroho, Novianto Adi; Suwandono, Adji; Sari, Maria Galuh Kamenyangan; Shofiyah, Laily
Sebatik Vol. 29 No. 2 (2025): December 2025
Publisher : STMIK Widya Cipta Dharma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46984/sebatik.v29i2.2640

Abstract

Furniture industry workers in Sambirembe Village, Sragen, face significant health risks from exposure to wood dust, particularly an increased risk of Chronic Obstructive Pulmonary Disease (COPD). This research is prompted by the low awareness among workers regarding these risks and the minimal use of personal protective equipment (PPE). The objective of this program was to increase workers' and business owners' knowledge of lung health, promote early detection of COPD, and encourage the adoption of safer work practices. The method employed was an intervention that included health education and lung function screening via questionnaires and spirometry. The results revealed a critical knowledge gap, where over 85% of workers had never heard of COPD, even though 70% of them reported experiencing respiratory symptoms. Furthermore, over 90% of workers admitted to rarely using masks. The intervention, which combined education with personalized spirometry data feedback, proved effective in increasing worker awareness of tangible health risks. In conclusion, the education-based and health-screening intervention program successfully raised furniture workers' understanding of COPD risks. An approach that integrates information with personal medical evidence is crucial for promoting behavioural change in high-risk work environments.
The Importance of Hyperthyroid Screening in Acute Decompensated Heart Failure with Persistent Tachycardia Despite Optimal Decongestion: A Case Report Myrtha, Risalina; Wijayanto, Matthew Aldo; Prabowo, Nurhasan Agung
Jurnal Kardiologi Indonesia Vol 46 No 4 (2025): October - December, 2025
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.2006

Abstract

In “The Importance of Hyperthyroid Screening in Acute Decompensated Heart Failure with Persistent Tachycardia Despite Optimal Decongestion: A Case Report” (Indonesian Journal of Cardiology, 43(3), 123-9. https://doi.org/10.30701/ijc.1328), there is an error noted. An error has been found in the PDF version of this article. The DOI printed in the PDF is incorrect. The correct DOI is https://doi.org/10.30701/ijc.1328. The error occurs only in the PDF; the DOI listed in the article metadata is already correct.The publisher apologizes for any inconvenience caused by this error.DOI of original article: https://doi.org/10.30701/ijc.1328
Umbilical Cord Mesenchymal Stem Cells Secretome in Osteoarthritis Patients: A Case Report Nurudhin, Arief; Prabowo, Nurhasan Agung; Wedhiningsih, Yulyani; Sunarso, Indrayana
Gema Lingkungan Kesehatan Vol. 23 No. 4 (2025): Gema Lingkungan Kesehatan
Publisher : Poltekkes Kemenkes Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36568/

Abstract

We report a case study of a 58-year-old lady diagnosed with symptomatic knee osteoarthritis (OA) who received umbilical cord-derived mesenchymal stem cell (UC-MSC) secretome via intra-articular injections once weekly for a total of five weeks. This treatment significantly reduced pain compared to the control, using a Visual Analog Scale, with pain scores reducing from 7/10 to 3/10. Moreover, the patient showed marked functional capacity improvement, as indicated by a Western Ontario and McMaster Universities Osteoarthritis Index score from 65 to 30. Her Kellgren-Lawrence grade also improved radiographically from 4 to 2 indicating either an initiation of cartilage regeneration or a reduction in degenerative change. These favorable results position the UC-MSC secretome as a novel and safe treatment for knee osteoarthritis, making it a potent non-invasive replacement therapy to classical treatments. The researchers advise that these findings must be confirmed in bigger, controlled trials before the therapeutic effects of UC-MSC secretome can be established in broader patient populations.
Co-Authors Adji Suwandono Adji Suwandono Andri Haryanto Anindita, Brigitta Devi Aprilningsih, Hendrastutik Apriningsih, Apriningsih Apriningsih Apriningsih, Hendrastutik Arief Nurudhin Arief Nurudhin Arief Nurudhin Arief Nurudhin Arief Nurudhin Arief Nurudhin Arifin Arifin Asih Anggraeni Astri Tantri Indriani Astri Tantri Indriani Astri Tantri Indriani Berty Denny Hermawati Bryan Arief Aji Rudita Coana Sukma Gautama Desy Puspa Putri Dyanneza, Frieska Evi Nurhayatun Evi Nurhayatun Fatichati Budiningsih Frieska Dyanneza Frieska Dyanneza Frieska Dyanneza Habibah, Sopia Nur Hafi Nurinasari Hartono Hartono Hendrastutik Apriningsih Hendrastutik Apriningsih Hendrastutik Apriningsih Hendrastutik Apriningsih Hermawati, Berty Denny Indriani, Astri Tantri Kuncorowati, Niken Dwi Aryani Kuncorowati, Niken Dyah Aryani Laily Shofiyah Laily Shofiyah Maria Galuh Kamenyangan Maria Galuh Kamenyangan Sari, Maria Galuh Kamenyangan Meirina Mulia Wardani Muchtar Hanafi Myrtha, Risalina Niken Dwi Aryani Kuncorowati Niken Dyah Aryani Kuncorowati Niken Dyah Aryani Kuncorowati Novianto Adi Nugroho Nugroho, Novianto Adi Putri, Desy Puspa Rachmah, Azkia Reviono Reviono Riandini Aisyah Risalina Myrtha Risalina Myrtha Risalina Myrtha Risalina Myrtha Shofiyah, Laily Sri Sulistyowati Sunarso, Indrayana Syahrini Wisdayanti Tamaulina Br Sembiring Tonang Dwi Ardyanto Wedhiningsih, Yulyani Werdiningsih, Yulyani Wijayanto, Matthew Aldo Yeni Farida Yulyani Werdiningsih Yulyani Werdiningsih Yulyani Werdiningsih Zainal Arifin Adnan Zainal Arifin Adnan