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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Medula Berkala Kedokteran Prosiding Seminar Nasional Pakar Manuju : Malahayati Nursing Journal Jurnal Ilmu Kedokteran dan Kesehatan Acta Biochimica Indonesiana Jurnal Ilmiah Kesehatan JK Unila (Jurnal Kedokteran Universitas Lampung) Jurnal Ilmu Kesehatan Indonesia (JIKSI) Prosiding Konferensi Nasional PKM-CSR Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Evi Kurniawaty
Universitas Lampung
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Antibacterial Screening of Mangrove Extract Library Showed Potential Activity against Escherichia coli and Staphylococcus aureus Kholis Abdurachim Audah; Razethy Batubara; Julkipli Julkipli; Elza Wijaya; Evi Kurniawaty; Irmanida Batubara
Journal of Tropical Life Science Vol. 10 No. 2 (2020)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.10.02.03

Abstract

Humans are at a continuous battle against different types of diseases, so that extraordinary effort to accelerate drug discovery has become a necessity. Indonesian biodiversity is abundant natural resources that can be utilized as potential drug sources. Mangroves are among potential plant medicines that grow nearly at all Indonesian coastlines. The aim of this study was to evaluate the potential of mangrove extracts (extract library) as antibacterial agents. In this study, eight mangroves species with 16 samples from different parts of the plants such as leaf, bark or root were collected. Four types of solvents with different polarity, namely water, ethanol, ethyl acetate and hexane were used in maceration of samples producing 64 extracts. Disk diffusion method was used for antibacterial screening using five bacterial strains. There were 37 extracts showed antibacterial potential with the lowest and the highest inhibition indexes were 0.0283 and 1.8983, respectively. The highest inhibition index was recorded for ethyl acetate extract of Bruguiera gymnorrhiza root (BgR (Ea)) against Escherichia coli. The second highest inhibition index was 0.7867 recorded water extract of Avicennia marina leaf (AmL (A)) against Staphylococcus aureus. Almost all of extract showed saponin and tannin in considerable amount. This supported the data that mangrove extracts were potential as antibacterial agents.
Co-Authors Ade Yonata Ari Wahyuni Arifaa Thalitha Z. Arifaa Thalitha Zuleikha Asep Sukohar Atikah Landani Bayu Anggileo Pramesona Charla Gutri Farmitali Della inike Putri Dyah Wulan SRW Elza Wijaya Erlita Kusuma Wardani Farida Hakim Lamuhammad Firza Syailindra Hendri Busman Herina Azzahra Huzaimah Huzaimah Iffa Afiqa Khairani Irmanida Batubara Julkipli Julkipli Kholis Abdurachim Audah Kholis Abdurachim Audah Liana Sidharti Liana Sidharti M. Azzaky Bimandama Mira Kurnia Nadia Gustria Dini Natasya Hayatillah Nisrina Pradya Nuning Nurcahyani Nuriah Nuriah Oktadoni Saputra Putu Karis Ayu Kirana Razethy Batubara Rodiani Rodiani Romanna Julia Duma Simanjuntak S Rahmanisa Shina Megaputri Silvia Andriani Silvia Andriani Silvia Andriani Silvia Andriani Soraya Rahmanisa Soraya Rahmanisa Soraya Rahmanisa Suharyani Suharyani Sultan Mahathir Bastha Susianti Susianti Syazili Mustofa T.A. Larasati TA Larasati Tiwuk Susantiningsih Tri Umiana Soleha Vania Widyadhari Damayanti W Bahagia Waluyo Rudiyanto Wildan Kautsar Irawan Winda Trijayanthi Utama, Winda Trijayanthi