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All Journal JOURNAL OF HEALTHCARE TECHNOLOGY AND MEDICINE JFM (Jurnal Farmasi Malahayati) Jurnal Ilmiah Manusia dan Kesehatan AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Anakes: Jurnal Ilmiah Analis Kesehatan GALENICAL : Jurnal Kedokteran dan Kesehatan Mahasiswa Malikussaleh Ahmad Dahlan Medical Journal Jurnal Sosial dan Sains Nanggroe: Journal Of Scholarly Service Journal of Pharmaceutical and Sciences. Nanggroe: Journal of Scholarly Service Auxilium : Jurnal Pengabdian Kesehatan
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UJI ZONA HAMBAT DAN UJI BEDA EKSTRAK ETANOL DAUN BIDARA (Z. MAURITIANA LAMM) TERHADAP BAKTERI STAPHYLOCOCCUS AUREUS Yuziani, Yuziani; Agtari, Yolanda; Novalia, Vera
JFM (Jurnal Farmasi Malahayati) Vol 8, No 1 (2025)
Publisher : Jurnal Farmasi Malahayati (JFM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jfm.v8i1.14427

Abstract

Penelitian ini bertujuan untuk mengetahui luas zona hambat dan uji beda dari tiap kelompok ekstrak etanol daun bidara (Z. mauritiana Lamm) terhadap pertumbuhan S. aureus. Penelitian ini merupakan penelitian eksperimental dengan 7 kelompok perlakuan. KN (kontrol negatif diberikan aquadest), KP (kontrol positif, diberikan Eritromisin), kelompok perlakuan konsentrasi ekstrak etanol yaitu P1 60%, P2 70%, P3 80%, P4 90%, P5 100%. Rancangan penelitian yang digunakan dengan jumlah 28 sampel yang dihitung menggunakan rumus Federer. Uji daya hambat dilakukan dengan metode difusi cakram. Data dianalisis menggunakan uji Anova menunjukkan nilai 0,000 (< 0,05) berbeda secara nyata dan dilanjutkan uji Post Hoc LSD. Hasil uji zona hambat ekstrak etanol daun bidara pada konsentrasi 60%, 70%, 80%, 90% dan 100% membentuk zona hambat rata-rata sebesar 9,24 mm, 8,79 mm, 9,30 mm, 10,15 mm, dan 10,99 mm, pada kelompok kontrol positif (eritromisin) sebesar 19,34 mm, dan pada kontrol negatif (aquadest) tidak terbentuk zona hambat. Dapat disimpulkan bahwa ekstrak etanol  daun bidara (Z. mauritiana Lamm) memiliki tingkat efektivitas yang lemah.
Pengaruh Ekstrak Rimpang Kunyit (Curcuma longa L.) Terhadap Aktivitas Motorik Tikus Putih Pada Model Parkinson Farisa, Siti; Ikhsan, Maulana; Novalia, Vera
Anakes : Jurnal Ilmiah Analis Kesehatan Vol. 11 No. 2 (2025): ANAKES: Jurnal Ilmiah Analis Kesehatan
Publisher : Universitas Mohammad Husni Thamrin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37012/anakes.v11i2.2917

Abstract

Parkinson's disease is a neurodegenerative disease characterized by movement disorders such as bradykinesia, rigidity, and tremor that can affect body balance, due to decreased dopamine levels that can be triggered by oxidative stress. Turmeric (Curcuma longa) contains curcumin which has antioxidant and neuroprotective properties, making it possible to prevent neurodegenerative disorders due to oxidative stress. Turmeric rhizome has a chemical content that is a yellow color substance called curcuminoids. This study aims to determine the effect of administering turmeric rhizome extract (Curcuma longa L.) on the motor activity of white rats (Rattus norvegicus) in the Parkinson's model. This study uses a laboratory test method using a pretest-posttest only control group design that uses white rat (Rattus novergicus) male wistar strain as the object of research. This study used 6 white rats carried out with 4 sample groups, with a total of 24 white rats (Rattus norvegicus) male wistar strains. This research has obtained ethical approval from the Ethics Committee of Health Research, Faculty of Medicine, Malikussaleh University, with letter number: 09/KEPK/FKUNIMAL-RSUCM/2023. The results showed that turmeric rhizome extract (Curcuma longa L.) at a dose of 600mg / kgBB had an effect on the motor activity of white rats (Rattus norvegicus) in the Parkinson's model, turmeric rhizome extract (Curcuma longa L.) at a dose of 400mg kgBB had an effect on the motor activity of white rats (Rattus norvegicus) in the Parkinson's model. There is no significant difference in the effect of turmeric rhizome extract between the dose groups of 400 mg/KgBB and 600 mg/KgBB on increasing the motor activity of white rats (Rattus norvegicus) in the Parkinson's model Keywords: Antioxidat, Haloperidol, Parkinson's Disease, Turmeric Rhizome, White Rat  
Co-Authors Adduana, Nuva Agtari, Yolanda Agustari, Farah Ahmad Fauzan Ami, Ghisca Chairiyah Andi Saputra Anjani, Raihannisa Ardiansyah, Tgk. Fikri Balqis, Ferisha Aulia Chairina, Nanda Cut Ita Zahara, Cut Ita Farisa, Siti Fauzan, Rivhan Hasibuan, Imam Irawan Saputra Hezelyn Aldelina Humairah, Helma Ikhsan, Maulana Imanda, Fetty Ita Zahara, Cut Julia Fitriany Julistia, Rini Khairunnisa Z Kholilullah, Vina Zaynah Lubis, Aisyah Nita Yasmin Mailyn, Yaiza Aynaya Mardiati Mardiati Maulina Debbyousha Mauliza, Mauliza Meutia Maulina, Meutia Meutia, Zahra Muna, Zurratul MZ, Dila Khairunnisa Nadira, Cut Sidrah Nasution, Muhammad Husni Fansury Nina Herlina Noviana Zara Putri, Baluqia Iskandar Qaristy, Hafiza Rahmi Surayya Rahmia Dewi, Rahmia Rizaldi, Muhammad Bayu Sahputri, Juwita Sarah Rahmayani Siregar Savitri, Dhannisa Ika Sayuti, Muhammad Teuku Ilhami Surya Akbar Ultsany, Mutia Utariningsih, Wheny Yuziani, Yuziani