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All Journal Indonesian Journal of Pharmaceutical Science and Technology SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Pharmaceutical Journal of Indonesia Jurnal Pengabdian Farmasi Malahayati (JPFM) Jurnal Pengabdian Kepada Masyarakat (Mediteg) Stannum : Jurnal Sains dan Terapan Kimia Jurnal Ilmiah Farmako Bahari Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang JPI (Jurnal Pendidikan Inklusi) INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) TRANSFORMASI : JURNAL PENGABDIAN PADA MASYARAKAT Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Klinik dan Sains Journal of Pharmaceutical and Sciences. Medical Sains : Jurnal Ilmiah Kefarmasian Masyarakat: Jurnal Pengabdian
Fatmawati, Annisa
Universitas Alma Ata
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Inhibition Activity Of Ethanolic Extract Of Ulva lactuca Against Staphylococcus aureus emelda, emelda; Safitri, Eka Asriani; Fatmawati, Annisa
Pharmaceutical Journal of Indonesia Vol. 7 No. 1 (2021)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2021.007.01.7

Abstract

Staphylococcus aureus (S. aureus) is a normal flora that can cause mild skin infections, one of which is acne. Commonly used chemical treatments are antibiotics such as Clindamycin. Continuous use of antibiotics can lead to resistance. Natural ingredients that are possible can inhibit the growth of bacteria. Treatment caused by S.aureus is Ulva lactuca Linn. (Green algae). This marine biota contains compounds that have the potential to be antibacterial, including triterpenoids, flavonoids, and saponins. This study aims to compare antibacterial activity of  ethanolic extract of Ulva lactuca and Clindamycin against S. aureus bacteria. This type of research is an experimental laboratory. Ulva lactuca was extracted by maceration method using ethanol 96% solvent. Then carried out testing for antibacterial activity using the agar diffusion method by sump technique. The study was divided into 6 groups. One Clindamycin group and 5 treatment groups respectively with extract concentrations of 20%, 40%, 60%, 80%, and 100%. The test was carried out in 3 repetitions. Data analysis was processed by SPSS using the Kruskal-Wallis test to determine which groups had difference. The results showed that the ethanolic extract of Ulva lactuca was able to inhibit the growth of S. aureus bacteria with strong categories at concentrations of 20%, 40%, and 60%. Very strong category at 80% and 100% concentrations. The 100% concentration had the largest average inhibition zone diameter of 22 ± 0.577 mm which was not significantly different from Clindamycin with a significance value of 0.043 (p <0.05). This study concludes that the ethanolic extract of Ulva lactuca has activity in inhibiting the growth of S.aureus bacteria with strong to very strong categories, but statistically not as strong as Clindamycin
Co-Authors Adelia, Melina Freda Adhi Gunawan Akbar, Jasmine Aulia Anisa Tri Hutami Aprilia, Veriani Ariski, Denis Ashari, Ayu - Aslam, M.Muzhil Asrori, Moh Astuti, Eka Dyah Ayu Bachri, Moch. Saiful Bahun, Nur Rohma Inayah Depita Sucianingsih Depita Sucianingsih Elvana, Azza emelda, emelda Emelda, Emelda Estiningsih, Daru Fauzi, Rizal Gerriandi, Aqila Aqhnia Gunawan, Adhi Hanifah, Wening Iswahjuni, Iswahjuni Jannah, Nurul Juliana, Intan Lahardo, Devanus Lestari, Yessi Manusu, Abd Sukri S Mastamah, Mastamah Muhammad Abdurrahman Muhammad Abdurrahman Munir Mulyaningsih, Sundari Munir, Muhammad Abdurrahman Nadia, Melta Ainun Nugroho, Novreza Avistha Nurhidayanti, Nurhidayanti Nurinda, Eva Nurinda, Eva Purbiastuti, Putri Ayu Puspitasari, Ade Putri, Imram Radne Rimba Putri, Nindya Tresiana Rahmadani, Andini Putri Rahmawati, Feti Ramadhani, Firmansyah Ardian Rendani, Ike Peny Riza Kurniawati Riza Kurniawati Rizal Fauzi Rizal Fauzi Safitri, Eka Asriani Sain Abrari Sarwadhamana, Raden Jaka Sati, Eva Laras Septiandi, Baiq Husnul Hotima Solikah, Wahyu Yuliana Sri Suprapti Suci Rahmawati, Suci Sucianingsih, Depita Suciati Suciati Tjandra, Edbert Rafael Veronika, Nabela Wijayanti, Galuh Candra Wiwied Ekasari Wulandari, Ari Susiana Yuliana, Khalifah Zendrato, Mei Albert Zuliyati, Isti Chana