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All Journal Folia Medica Indonesiana Jurnal Media Gizi Indonesia (MGI) Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Education The Indonesian Journal of Public Health Sari Pediatri Health Notions Amerta Nutrition Journal of Telenursing (JOTING) Indian Journal of Forensic Medicine & Toxicology Archives of Pediatric Gastroenterology, Hepatology, and Nutrition Berita Kedokteran Masyarakat Asian Journal of Social and Humanities Jurnal Kesehatan Masyarakat
Nur Aisiyah Widjaja, Nur Aisiyah
Child Health Department, Faculty Of Medicine, Dr Soetomo General Hospital, Surabaya, Indonesia
Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Education Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Other

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`Socio-Demographic Association with Nutritional Status in Children Aged 8-9 Years Old in Surabaya: Focusing on HAZ Status in Path Analysis Ardianah, Eva; Indriani, Diah; Soenarnatalina, Melaniani; Widjaja, Nur Aisiyah; Santoso, Febrina Mustika
Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Education Vol. 13 No. SI1 (2025): Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Educat
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jpk.V13.ISI1.2025.1-15

Abstract

Background: Child health, growth, and nutrition are influenced by socioeconomic, cultural, demographic, climatic, nutrition, physical, hygiene, sanitation, medical, and environmental factors. LAZ/HAZ was used to assess the presence of 'stunting' in the population, which indicates chronic malnutrition. Objectives: to investigate the socio-demographics, lifestyle (sleep duration, screen time) and HAZ status of children in 2nd and 3rd grade of elementary school, and the correlation of socio-demographics with the anthropometric parameters. Methods: An observational study with a cross-sectional design was conducted during October – December 2022 in Surabaya, involving healthy children aged 9-10 years old who were in 2nd and 3rd grade of elementary school. Results: BMI-for-age z-score was higher in males than females. Overweight/obesity were prevalent in males (15.16% vs. 10.67%), and underweight and severely underweight were prevalent in females (12.27% vs. 14.23%). The prevalence of stunted/severely stunted was 12.39%. HAZ and WAZ were correlated positively with parental height. The number of children in the household had a negative, weak correlation with HAZ. The maternal education showed that the prevalence of maximal elementary school graduation was higher in stunted children than in normal children (29.27% vs. 18.14%, p=0.043). Fathers' salaries below minimum regional wage were more prevalent among stunted and severely stunted (81.71% and 75%, respectively) than normal subjects (60%), p=0.007. Conclusion: Socio-demographic factors affecting the prevalence of stunting in children were the father's salary and maternal education. Meanwhile, factors associated with HAZ were parental height and number of children in the household. The effect of socio-demography on HAZ was mediated by parental education, which stimulates household economics and has a further effect on food intake and child anthropometrics.
PHYSICAL BEHAVIOURS IN ADOLESCENTS THAT CONTRIBUTE TO OVERWEIGHT/OBESITY Keya , Rino Tryanto; Widjaja, Nur Aisiyah; Noviyanti, Tausiyah Rohmah; Alexander, Yoppi Yeremia; Iitdrie, Iitdrie; Hermanto, Edi; Ardianah, Eva; Bahmid, Moh; Hanindita, Meta Herdiana; Irawan, Roedi
Media Gizi Indonesia Vol. 20 No. 1 (2025): MEDIA GIZI INDONESIA (NATIONAL NUTRITION JOURNAL)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v20i1.12-20

Abstract

Physical behaviours research in adolescents is still limiting in regard of overweight/obesity. Physical behaviour according to World Health Organization Global School Student Health Survey (WHO-GSHS) had four components namely physical activity, active transportation, physical education and sedentary behaviour showed inconsistent results investigating the obesity/overweight epidemic. The objective of this study is to examine the physical behaviour and metabolic components in overweight/obese adolescents. A cross-sectional study was conducted from September to October 2019 involving healthy obese adolescents with overweight/obesity in Sidoarjo and Surabaya. The statistical analysis was test of normality for interval/ratio variables, descriptive, bivariate correlation and binary logistic regression. All the analysis were conducted using SPSS ver. 21 (IBM, US). A total of 109 subjects were recruited in this study, consisting of male (50.46%) and female (49.54%) adolescents. The mean age of the subjects were 15.13 + 1.46 years old. Adolescents with sufficient physical activity, physical transport, physical class and recommended screen time was 93.58%, 23.85%, 14.68% and 36.70% respectively. The overweight subjects were 63 (57.80%) and obesity was 46 (42.20%), and prevalent in male than female (65.22% vs. 34.78%, p=0.012). The prevalent of MetS was 53.21%, no significant difference of MetS distribution among male and female (p=0.506). Subjects with physically transport behaviour had lower risk of abdominal obesity by 0.266-times than subjects with physically immobile. Thus, physical behaviour score did not correlate with anthropometric parameters indicating to overweight/obesity and metabolic factors, but the component of physical behaviour, especially sedentary lifestyle correlated with anthropometric parameters and systolic blood pressure.
Effect of Different Complementary Feeding on Iron Deficiency Anemia and Growth in Breastfed Infants: Home-Made VS Commercial Irawan, Roedi; Widjaja, Nur Aisiyah; Hanindita, Meta Herdiana
Folia Medica Indonesiana Vol. 55 No. 2 (2019): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (148.459 KB) | DOI: 10.20473/fmi.v55i2.24594

Abstract

After approximately 6 months of age, term breastfed infants are increasingly depend on other sources of iron to avoid iron deficiency anemia, due to the depletion of the low concentration of iron in human milk. The appropriate complementary feeding must include a balance composition of foods containing an adequate amount of macro- and micronutrients to avoid iron deficiency anemia. This study aimed to compare the risk of iron deficiency and growth in breastfeed infants receiving commercial fortified complementary foods or home-made. A cross-sectional study was held on April-June 2016 to evaluate infants aged 6-24 months with breast feeding intake for 6 month of life. Complementary feeding practices were determined by questionnaire; an unquantified food frequency and feeding practices questionnaire was used to determine usual food intake. Biochemical assessment of haemoglobin (Hb), serum ferritin (SF) and serum iron (SI) level were measured. Anthropometric were assessed using WHO Child Growth Standard 2005. Statistical analysis used were Chi-square Test. Thirty eight infants were enrolled, mean age of 16.2 (SD 10.5) months. 17 infants consumed commercial complementary foods and 21 infants use home-made. Infants with home-made had lower Hb level, SF and SI  than those receiving commercial complementary food, and had higher risk of underweight, stunted and wasted. Infants with home-made complementary food had lower haemoglobin, serum feritin and serum iron levels than those in fortified complementary food CF; and a higher risk of stunted and wasted than children with commercial fortified CF.
The Effects of Cigarette Smoke Exposure on Anthropometric Measurements, Lipid Profile, Fasting Blood Glucose, Fasting Insulin, and Blood Pressure in Overweight/Obese Adolescents Widjaja, Nur Aisiyah; Claudia Felisia Magdalena Kurube; Febrina Mustika Santoso; Noviyanti, Tausyiah Rohmah; Alexander, Yoppi Yeremia; Keya, Rino Tryanto; Hermanto, Edi; Iitdrie; Ardianah, Eva; Amer Siddiq Amer Nordin
Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Education Vol. 13 No. 1 (2025): Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Educatio
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jpk.V13.I1.2025.47-55

Abstract

Background: Cigarette smoke exposure increases the risk of obesity, metabolic syndrome, hypertension, hyperglycemia, and dyslipidemia. The nicotine content in cigarettes can acutely increase energy expenditure, decrease appetite, and several other chronic diseases such as cardiovascular disease, lung disease, cancer, and so on. Objectives: This study aims to determine the effect of cigarette smoke exposure on anthropometric measurements, lipid profiles, fasting blood glucose, fasting insulin, and blood pressure in overweight/obese adolescents. Methods: This was a cross-sectional study involving overweight/obese adolescents conducted from September to October 2019 to evaluate the effects of tobacco exposure on anthropometric measurements, lipid profile, fasting blood glucose (FBG), fasting insulin, and blood pressure. Results: This study showed no significant differences in the age distribution, body weight, body height, height-for-age z-score (HAZ), hip circumference, body mass index (BMI), BMI-for-age z-score, fasting insulin, FBG, lipid profile, and blood pressure between low, moderate, and high cigarette smoke exposure in overweight/obese adolescents, but the high exposure group had a bigger waist circumference than the moderate exposure group (107,45 + 11,25 vs 99,35 + 11,36 cm, p = 0,019) and low exposure (107,45 + 11,25 vs 99,04 + 12,08 cm, p = 0,015). Conclusion: The degree of exposure to heavy cigarette smoke has a greater waist circumference than exposure to light and moderate cigarette smoke. Cigarette smoke exposure is significantly associated with body weight and hip circumference, and heavy cigarette smoke exposure is prevalent in adolescent boys.
NUTRITIONAL INTERVENTION IN STUNTING CHILDREN AGED 1-5 YEARS-OLD USING ORAL NUTRITIONAL SUPPLEMENTS (ONS) IN SURABAYA CITY Alexander, Yoppi Yeremia; Widjaja, Nur Aisiyah; Irawan, Roedi; Hanindita, Meta Herdiana; Noviyanti, Tausyiah Rohmah; Keya, Rino Tryanto; Hermanto, Edi; Bahmid, Moh.; Iitdrie, Iitdrie
Media Gizi Indonesia Vol. 20 No. 2 (2025): MEDIA GIZI INDONESIA (NATIONAL NUTRITION JOURNAL)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v20i2.168-177

Abstract

Growth faltering, also known as failure to thrive, in pediatric populations may arise from a combination of insufficient nutritional intake and the presence of chronic infections. When this condition persists over an extended duration, it can culminate in stunting—a form of chronic malnutrition characterized by impaired linear growth—which continues to exhibit a high prevalence rate across various regions of Indonesia. As part of the national effort to mitigate and prevent stunting, oral nutritional supplements (ONS), which are specifically formulated for both therapeutic and dietary management in pediatric patients with specific health conditions, including growth failure, play a critical role. This study aims to examine the impact of ONS intervention, with a caloric density of approximately 1 kilocalorie per milliliter, on stunted children between the ages of one and five years at a private healthcare facility, namely Husada Utama Hospital in Surabaya. This study is an observational analytical study of a quasi- randomized control trial with a pre- and post-test design. The sample of this study was stunting children aged 1-5 years as many as 20 subjects who were willing to follow the ONS intervention research in achieving optimal growth. After being given intervention for 90 days, the number of normal HAZ/LAZ children became 5 (25% increase). There was a decrease from severely stunting by 7 subjects to stunting and a decrease in stunting to normal by 5 subjects
Immune response in IGF-1 and growth parameters among infected children Ardianah, Eva; Widjaja, Nur Aisiyah; Indriani, Diah; Melaniani, Soenarnatalina; Kuntoro; Wibowo, Arief; Notobroto, Hari Basuki; Purnomo, Windhu; Indawati, Rachmah; Saputro, Sigit Ari; Santoso, Febrina Mustika; Puspitasari, Ria; Pebriaini, Prisma Andita; Nurfidaus, Yasmine; Irawan, Roedi; Hidayat, Boerhan; Hidayati, Siti Nurul; Hanindita, Meta Herdiana
BKM Public Health and Community Medicine Vol 41 No 08 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/bkm.v41i08.18379

Abstract

Purpose: Infections in children can affect weight gain and linear growth by influencing metabolism and nutrition. Chronic inflammation results in growth failure mediated by pro-inflammatory cytokines and poor nutritional intake, which affects the GH/IGF-1 axis. This study aimed to investigate the impact of the inflammatory response on children's anthropometry, particularly HAZ, and the role of IGF-1. Methods: An observational study with a cross-sectional design was conducted from September 2021 to July 2022. The study involved children diagnosed with infections. The subjects had undergone a physical and laboratory investigation, which included a thorax photo, urine culture, Mantoux test, and complete blood test in a hospital setting. A complete medical history was obtained from the pediatrician. Results: The prevalence of undernutrition was 37.33%; the prevalence of underweight/severely underweight, stunted/severely stunted, and wasted/severely wasted was 25.33%, 30.66%, and 14.67% respectively. Stunted/severely stunted was more prevalent in subjects under 2 years old, compared to subjects more than 2 years old (22/41 vs. 7/34, p=0.014). SEM analysis revealed that the inflammatory response affected IGF-1 levels (r=0.850, p=0.000), while IGF-1 affected body composition (r=0.245, p=0.025), and then affected HAZ (r=1.000, p=0.000). The effect of IGF-1 on HAZ appears to be indirect, acting through body composition. Parental height has a weak, albeit significant, effect on body composition (r=0.101, p=0.025) and HAZ (r=0.192, p=0.040). Univariate analysis revealed strong correlations between IL-6 and IL-10 and IGF-1 (r=0.870, p=0.000 and 0.876, p=0.000, respectively). In contrast, parental height showed a correlation with HAZ/LAZ (r=0.319, p=0.000). Maternal height was correlated positively with WAZ (r=0.320, p=0.044). Conclusion: The prevalence of stunting among children under two years of age indicates that early childhood constitutes a critical period for intervention in growth and development. Inflammatory response has been demonstrated to influence IGF-1 levels in children. The role of IGF-1 on HAZ was mediated by body composition.
Unlocking The Efficacy of Tetrahydrobiopterin (BH4) Towards Metabolic Profile and Growth Status in Children with Phenylketonuria: A Meta Analysis Rafi Alfian Razan; Nur Aisiyah Widjaja; Anggie Lorenza; Vianca Samara Andhary; Naoval Diza Ananda
Archives of Pediatric Gastroenterology, Hepatology, and Nutrition Vol. 4 No. 3 (2025): APGHN Vol. 4 No. 3 August 2025
Publisher : The Indonesian Society of Pediatric Gastroenterology, Hepatology, and Nutrition

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58427/apghn.4.3.2025.111-128

Abstract

Background: Phenylketonuria (PKU) is one of the most common types of inborn error of metabolism. Low-phenylalanine diet has been the main treatment for children with PKU. However, recent therapeutic alternatives have emerged as a solution in children with PKU in the form of tetrahydrobiopterin (BH4). This meta analysis aims to assess the effectiveness of BH4 in terms of response rate, metabolic profile and growth status. Methods: Meta analysis was conducted by searching databases such as PubMed, ScienceDirect, Cochrane Library, medRxiv, and Scopus based on the Preferred Reporting Items for Systematic Reviews and Meta Analysis (PRISMA) guidelines. Data synthesis and analyses were conducted using R version 4.5.1 (R Foundation for Statistical Computing). Result: Fifteen studies were involved in this research, consisting of 1280 children (1063 given BH4). Eight studies reported BH4 reduced plasma phenylalanine concentration by around (686.83 mg/day [95% CI 394.85 to 978.82], p <0.001). Additionally, two studies reported a reduction in plasma phenylalanine concentration, measured in mg/kg/day, following BH4 administration. Children given BH4 and low phenylalanine diet combination showed a higher response rate compared to BH4 only (100% vs 76%). Two studies showed no difference in growth outcomes, which remained within the normal range. Conclusion: BH4 shows promise as an adjunct therapy for children with PKU, but confirmation through larger, standardized, long-term studies assessing outcomes such as growth status and long-term neurocognitive outcome is needed.
SLEEP DURATION, ANTHROPOMETRIC MEASUREMENTS AND METABOLIC SYNDROME IN OVERWEIGHT/OBESE ADOLESCENTS Iitdrie; Widjaja, Nur Aisiyah; Hanindita, Meta Herdiana; Irawan, Roedi; Qomaruddin, Mochammad Bagus; Muthmainnah, Muthmainnah; Ardianah, Eva; Noviyanti, Tausyiah Rohmah; Alexander, Yoppi Yeremia; Keya, Rino Tryanto; Hermanto, Edi
Media Gizi Indonesia Vol. 20 No. 3 (2025): MEDIA GIZI INDONESIA (NATIONAL NUTRITION JOURNAL)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v20i3.356-362

Abstract

Introduction: Adolescents have sleep problems, as their sleep duration does not meet the recommended sleep duration of 8-10 hours, leading to various sleep-related problems. Sleep duration is suspected to have detrimental effects on health, such as non-communicable diseases including obesity, cardiovascular disease (CVD), and type 2 diabetes mellitus (T2DM). However, the correlation between sleep duration and the prevalence of obesity and metabolic syndrome (MetS) is still conflicting, especially in the adolescent population. This study aimed to examine and analyze the effect of sleep duration on anthropometric measurements and MetS in overweight/obese adolescents. Methods: A cross-sectional study involving healthy overweight/obese adolescents was conducted from September to October 2019 to evaluate the effect of sleep duration on anthropometric measurements, lipid profiles, fasting blood glucose levels, and blood pressure in overweight/obese adolescents. Results and discussion: A total of 197 subjects showed no significant differences in body height, BMI, waist circumference, blood pressure, and lipid profile based on sleep duration categories. Subjects with short sleepers were older than those with sufficient sleep (p<0.05). However, long sleepers were heavier, had larger BMI-for-age z-scores, and larger waist circumferences than sufficient and short sleepers (p<0.05). However, the differences between the short, sufficient, and long sleepers were U-shaped. Sleep duration was not correlated with MetS or MetS components (abdominal obesity, hyperglycemia, hypertriglyceridemia, hypertension, and low HDL-c). Conclusion: Long sleepers (>11 h/night) were heavier, had greater BMI-for-age z-scores, and larger waist circumference than (<sufficient sleeper (6-10 h/night), or short sleepers 6 h/night).
Screen Time, Anthropometric Parameter, Insulin and HOMA IR in Adolescents Widjaja, Nur Aisiyah; Arifani, Rizka; Noviyanti, Tausiyah Rohmah; Alexander, Yoppi Yeremia; Hermanto, Edi; Iitdrie, Iitdrie; Ardianah, Eva; Keya, Rino Tryanto
Jurnal Kesehatan Masyarakat Vol. 21 No. 2 (2025)
Publisher : Universitas Negeri Semarang in collaboration with Ikatan Ahli Kesehatan Masyarakat Indonesia (IAKMI Tingkat Pusat) and Jejaring Nasional Pendidikan Kesehatan (JNPK)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v21i2.6265

Abstract

The rapid integration of digital technology into daily life, particularly among adolescents, has generated increased screen time exposure. This study investigates the effect of screen time on anthropometric parameters, insulin levels, and HOMA IR in adolescents, regarding the increasing concerns about its potential health implications. Methods: A cross-sectional study involving 131 healthy adolescents (aged 12-18) was conducted to assess an anthropometric measurements, blood investigations (lipid profile, fasting blood glucose, fasting insulin), blood pressure, and screen time assessments. Screen time was categorized as recommended, moderate, and heavy. Results and Discussion: The moderate screen time was associated with a higher risk of overweight (OR=5.643), obesity (OR=3.737), insulin resistance (OR=4.116), and metabolic syndrome (OR=2.185). Heavy screen time showed higher risks for being overweight and metabolic syndrome (OR=32.421), but did not correlate significantly with overweight or obesity. The findings suggest a significant association between screen time and adverse health outcomes in adolescents, particularly for moderate and heavy screen time. Heavy screen time demonstrated substantial risks, emphasizing the need for interventions to mitigate potential health consequences. Conclusion: Screen time has noteworthy implications on the health of adolescents, with significant associations observed on anthropometric parameters, insulin resistance, and metabolic syndrome.
Co-Authors Adha, Aziza Zahrotul Alexander Leonard Caesar Josediputra Alexander, Yoppi Yeremia Amer Siddiq Amer Nordin Anggie Lorenza Ardianah, Eva Ariandi Setiawan Arief Wibowo Arifani, Rizka Azzahra', Lama'ah Bahmid, Moh Bahmid, Moh. Boerhan Hidayat Boerhan Hidayat, Boerhan Christine Florens Christine Florens Claudia Felisia Magdalena Kurube Diah Indriani Dina Angelika Dwi Lestari Avianti Eddy Bagus Wasito Febrina Mustika Santoso Hafiza Amadhin Rusti Hanindita, Meta Herdiana Hanindita, Meta Herdiana Hardiani, Kartika Hari Basuki Notobroto Harits, Muhammad Hendrayani, Ayu Ekanita HERMANTO, EDI Iitdrie Iitdrie, Iitdrie Keya , Rino Tryanto Keya, Rino Tryanto Khadijah Rizky Sumitro Khadijah Rizky Sumitro KUNTORO Meity Ardiana Mochammad Bagus Qomaruddin Muthmainnah Muthmainnah Naoval Diza Ananda Noviyanti, Tausiyah Rohmah Noviyanti, Tausyiah Rohmah Nurfidaus, Yasmine Nurfirdaus, Yasmine Pebriaini, Prisma Andita Putri Ardina Maharani Rachmah Indawati Rafi Alfian Razan Rendi Aji Prihaningtyas Rendi Aji Prihaningtyas Rendi Aji Prihaningtyas Rendi Aji Prihaningtyas Rendi Aji Prihaningtyas Ria Puspitasari Roedi Irawan Santoso, Febrina Mustika Sigit Ari Saputro SITI NURUL HIDAYATI Soenarnatalina Melaniani Soenarnatalina, Melaniani Sri Widati Vianca Samara Andhary Windhu Purnomo