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All Journal World Chemical Engineering Journal JURNAL INTEGRASI PROSES Teknika: Jurnal Sains dan Teknologi Biology, Medicine, & Natural Product Chemistry Aplikasia: Jurnal Aplikasi Ilmu-Ilmu Agama JURNAL FARMASIMED (JFM) Indonesian Journal of Cosmetics Journal of Chemistry Sciences and Education
Herayati, Herayati
Center Of Excellence For Local Food Innovation University Of Sultan Ageng Tirtayasa Department Of Chemical Enginering, Universitas Sultan Ageng Tirtayasa Banten
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Natural-Based Cosmetics: Trends, Challenges, and Scientific Innovations Herayati, Herayati; Elianasari, Elianasari
Indonesian Journal of Cosmetics Vol. 2 No. 2 (2024): Indonesian Journal of Cosmetics
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM), Institut Teknologi Sumatera, Lampung Selatan, Lampung, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35472/ijcos.v2i2.1992

Abstract

The increasing demand for natural-based cosmetics has reshaped the beauty industry, driven by consumers seeking sustainable, eco-friendly, and ethically sourced products. This review explores the current trends, formulation challenges, and scientific innovations in the development of natural-based cosmetics. Key natural ingredients, such as plant extracts, oils, and waxes, are discussed in terms of their benefits, limitations, and formulation complexities. The article also addresses significant hurdles, including stability issues, the need for natural preservation systems, and consumer expectations for product efficacy and sensory experience. Advances in green chemistry, biotechnology, and encapsulation technologies are highlighted as critical drivers for overcoming these challenges. Innovations such as plant stem cells, microbial fermentation, and nanoemulsions have enhanced the performance and stability of natural actives. Looking ahead, the future of natural-based cosmetics lies in further integration of green biotechnologies to create more effective and sustainable bioactive ingredients. By embracing these innovations, the beauty industry is poised to meet consumer demands for high-performance products that are not only natural but also sustainable and ethically transparent.
THE IDENTIFICATION OF BIOACTIVE COMPOUNDS IN BUTTERFLY PEA (Clitoria ternatea L.) FLOWER SIMPLICIA: A MACROSCOPIC, MICROSCOPIC, AND PHYTOCHEMICAL STUDY Elianasari, Elianasari; Herayati, Herayati; Handayani, Kiki Yuli; Astuti, Puput Puji
Indonesian Journal of Cosmetics Vol. 2 No. 2 (2024): Indonesian Journal of Cosmetics
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM), Institut Teknologi Sumatera, Lampung Selatan, Lampung, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35472/ijcos.v2i2.2059

Abstract

The butterfly pea flower (Clitoria ternatea L.) is known for its distinctive purple petals. This plant typically grows as an ornamental and can be used as a natural eye remedy and food coloring, safe for human consumption. This study aims to investigate the characteristics and perform a phytochemical screening of the butterfly pea flower (Clitoria ternatea L.). The characteristics of the flower simplicia were examined through macroscopic and microscopic observations, followed by a phytochemical screening process, which included testing for alkaloids, flavonoids, saponins, tannins, and terpenoids/steroids using specific reagents. Additionally, non-specific characteristics, such as moisture content, were analyzed. The results indicate that the flower simplicia has a distinct odor, is tasteless, blue in color, and appears in a dry form. Microscopically, the flower simplicia revealed single grains and thin slices, showing epidermal cell fragments with stomata and crystal fibers with vascular bundles. The phytochemical screening confirmed the presence of alkaloids, saponins, and flavonoids, while tannins and terpenoids/steroids were absent.
THE POTENTIAL OF FRAGRANT PANDAN LEAVES AS ACTIVE INGREDIENTS IN COSMETIC PRODUCTS: PHYTOCHEMICAL ANALYSIS Nurbaiti, Siwi; Bella Triyanti, Sinta; Herayati, Herayati
Indonesian Journal of Cosmetics Vol. 3 No. 1 (2025): Indonesian Journal of Cosmetics
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM), Institut Teknologi Sumatera, Lampung Selatan, Lampung, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35472/ijcos.v3i1.2277

Abstract

This study aimed to evaluate the phytochemical composition of Pandanus amaryllifolius (fragrant pandan) leaf extract as a preliminary assessment of its potential application in herbal cosmetic formulations. The extraction was performed using the maceration method with 95% ethanol as the solvent. Qualitative phytochemical screening was conducted to identify major classes of secondary metabolites. The results confirmed the presence of alkaloids, flavonoids, tannins, polyphenols, and saponins, while steroids and triterpenoids were not detected. Each identified compound group is known to contribute important biological activities, including antioxidant, anti-inflammatory, and antimicrobial effects, which are desirable in topical skincare products. These findings provide foundational evidence that P. amaryllifolius leaves are a promising natural source of multifunctional bioactive compounds for future cosmeceutical development.
Perbandingan Metode Ekstraksi Maserasi, Sokletasi, Dan Sonikasi Terhadap Nilai Rendemen Ekstrak Rimpang Kunyit (Curcuma Longa L.) Annisa Rahma Aryanti; Made Helen Susanti; Anjar Hermadi Saputro; Herayati; Indah Puspita Sari; Syahjoko Saputra, Iwan
Journal of Chemistry Sciences and Education Vol 2 No 01 (2025): Journal of Chemistry Sciences and Education
Publisher : PT. Pubsains Nur Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69606/jcse.v2i01.237

Abstract

This study aims to determine the comparison of maceration, soxhletation, and sonication extraction methods on the yield value of turmeric rhizome (Curcuma longa L.). Extraction was carried out using methanol and n-hexane solvents. The extraction process produces turmeric extract with different colors, textures, and aromas depending on the method used. The maceration, soxhletation, and sonication methods have different impacts on the yield of the extract, but the basic principle is the same in filtering active substances from the sample. The yield value obtained from the maceration method is 0.4996% soxhletation 0.0013% and sonication 0.0071%. The maceration method is proven to provide the highest extract yield compared to the soxhletation and sonication methods, which is 0.4996%.
Synthesis, Characterization, and Micellar Behavior of Amphiphilic Chitosan Bearing Sulfate and Anisaldehyde Imine Groups Herayati, Herayati; Wahyuningrum, Deana; Bima, Damar Nurwahyu; Sari, Indah Puspita
Biology, Medicine, & Natural Product Chemistry Vol 14, No 2 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.142.905-909

Abstract

Amphiphilic chitosan derivatives bearing sulfate and anisaldehyde imine (anisimine) groups were successfully synthesized and characterized for potential applications as functional biomaterials. The synthesis involved two key steps: (1) sulfation of chitosan using chlorosulfonic acid to introduce O-sulfate groups, and (2) Schiff base formation via reaction with p-anisaldehyde to generate N-anisimine functionalities. Structural modifications were confirmed by Fourier-transform infrared (FTIR) spectroscopy, which showed characteristic absorption bands at ~1250 cm-¹ and ~820 cm-¹ corresponding to O=S=O stretching of sulfate, and a C=N stretch at ~1640 cm-¹ indicating imine formation. Proton nuclear magnetic resonance (1H-NMR) spectra further verified the successful attachment of aromatic protons from p-anisaldehyde and the disappearance of primary amine peaks, confirming imination. The amphiphilic behavior and micelle-forming ability of the N-anisimine-O-sulfated (NAOS) chitosan were evaluated using pyrene as a hydrophobic fluorescent probe for determining the critical micelle concentration (CMC), which was found to be 0.012 mg/mL. The observed low CMC value indicates strong self-assembly capability in aqueous media. These results suggest that NAOS chitosan possesses promising structural and surface-active properties suitable for advanced applications in drug delivery and cosmetic formulations.
Perbandingan Efektivitas Metode Maserasi, Digesti, dan Sokletasi terhadap Nilai Konsentrasi Larutan Stok Ekstrak Daun Singkong (Manihot esculenta Crantz) Nieyan, Putri Ananda; Hakiki, Salsabila Sofia; Rahim, Audy Nasyiah; Azizah, Anis; Nurrahmah, Salsabila; Herayati; Saputra, Iwan Syahjok
Journal of Chemistry Sciences and Education Vol 2 No 02 (2025): Journal of Chemistry Sciences and Education
Publisher : PT. Pubsains Nur Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69606/jcse.v2i02.263

Abstract

Cassava leaves (Manihot esculenta Crantz) are known to contain various bioactive compounds such as flavonoids, tannins, saponins, and alkaloids. This study aimed to compare the effectiveness of three extraction methods maceration, digestion, and Soxhlet extraction in producing stock solutions of cassava leaf extract. A total of 5 grams of cassava leaf simplicia was extracted using methanol 96% (maceration), distilled water (digestion), and methanol 99.9% (Soxhlet). The extract yield was measured by evaporating 1 mL of filtrate and weighing the residue. The results showed that the Soxhlet method produced the highest concentration of 0.085%, followed by digestion (0.0132%) and maceration (0.0106%). Soxhlet extraction was more effective due to its continuous solvent circulation at elevated temperatures and higher solvent volume, resulting in a more efficient extraction of active compounds from the cassava leaves.
Optimasi Ekstraksi Daun Pandan (Pandanus amaryllifolius) dengan Metode Maserasi, Ultrasonik, dan Sokletasi: Perbandingan Hasil dan Efisiensi Pebriyanti, Ine; Mentari, Corona; Saputra, Iwan Syahjoko; Sari, Indah Puspita; Herayati; Saputro, Anjar Hermadi
Journal of Chemistry Sciences and Education Vol 2 No 02 (2025): Journal of Chemistry Sciences and Education
Publisher : PT. Pubsains Nur Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69606/jcse.v2i02.315

Abstract

Pandan (Pandanus amaryllifolius) merupakan tanaman yang memiliki kandungan bioaktif yang dapat memberikan efek antibakteri terhadap Staphylococcus aureus dan Staphylococcus epidermis. Tujuan penelitian ini yaitu membandingkan efektivitas metode maserasi, ultrasonik, dan sokletasi dalam mengekstrak senyawa bioaktif. Penelitian dilakukan secara eksperimen, sampel diekstraksi dengan cara maserasi, sokletasi, dan ultrasonik selama 1 jam dengan menggunakan pelarut metanol. Hasil konsentrasi larutan stok ekstrak daun pandan wangi yang diperoleh dari metode maserasi sebesar 0.49%; metode sokletasi sebesar 3%, dan metode ultrasonik sebesar 3,90%. Daun pandan segar menghasilkan serbuk simplisia dengan rendemen 24,89%. Penelitian ini membandingkan efektivitas ekstraksi senyawa metabolit sekunder menggunakan metode maserasi, sokletasi, dan ultarsonik. Maserasi menghasilkan fraksi polar dominan dengan konsentrasi 0,49% (m/v), ultrasonik menghasilkan ekstrak 3,90% (m/v), dan sokletasi 3% (m/v). Warna hijau tua pekat pada ekstrak mengindikasikan keberadaan senyawa bioaktif seperti flavonoid dan klorofil. Semua metode terbukti efektif dalam mengekstraksi senyawa aktif dari daun pandan.
Ekstraksi Daun Kelor (Moringa Oliefera) dengan Metode Maserasi, Ultrasonik, dan Sokletasi: Perbandingan Hasil dan Efisiensi Izzati, Aluna Monalaika; Margareth, Angelica; Mahardika, Aurellia Azzahra; Dewi, Dea Puspa; Salsabila, Keisya Yumna; Ayudya, Malika Aziza; Karima, Naura Putri; Rahmadani, Sinta; Mufaza, Wahya; Herayati; Syaputra, Iwan Syahjoko
Journal of Chemistry Sciences and Education Vol 2 No 02 (2025): Journal of Chemistry Sciences and Education
Publisher : PT. Pubsains Nur Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69606/jcse.v2i02.326

Abstract

This research aims to optimize the extraction method for natural compounds from the Moringa oleifera plant in order to obtain the most effective method for isolating bioactive compounds that have the potential to be applied in natural cosmetic products. Four extraction techniques were compared in this study, namely ultrasonic extraction, maceration, digestion, and soxhletation, using methanol, n-hexane, and water as solvents. The highest yield was obtained from the ultrasonic assisted extraction (UAE) method with a concentration of 2.4% (w/v) this method is carried out for 60 minutes using a frequency of 60 kHz, followed by soxhletation at 0.8% (w/v). Phytochemical tests showed the presence of flavonoids, tannins, alkaloids and terpenoids, while saponins were not detected in several solvent systems due to differences in polarity. These results show that the UAE method is the most efficient technique for isolating active compounds from Moringa leaves, so it has the potential to be used in the formulation of natural cosmetic preparations, especially as an antioxidant in skin care.
THE OPTIMALIZATION OF EXTRACTION METHOD OF AVOCADO LEAVES Herayati, Herayati; Fitri Nadiyah, Syakirah
Indonesian Journal of Cosmetics Vol. 3 No. 2 (2025): Indonesian Journal of Cosmetics
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM), Institut Teknologi Sumatera, Lampung Selatan, Lampung, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35472/ijcos.v3i2.2489

Abstract

This study aims to determine the most effective extraction method to obtain bioactive compounds from avocado (Persea americana Mill.) leaves, which are known for their antioxidant and antibacterial activities. Four extraction methods were evaluated—maceration, digestion, Soxhlet extraction, and ultrasonic extraction—using methanol and water as solvents. Evaluation was based on yield and stock solution concentration. Results showed that ultrasonic extraction produced the highest yield with a stock concentration of 2.5% m/v, indicating superior extraction efficiency compared to the other methods. Maceration and Soxhlet extraction produced moderate values, while digestion produced the lowest stock solution concentration (0.9%). These findings indicate that ultrasonic extraction is a rapid and efficient technique for extracting bioactive compounds from natural materials, making it highly relevant for application in cosmetic and pharmaceutical product development.
Co-Authors Agus Rochmat Agus Rochmat Agus Rochmat Agus Rochmat Agus Rochmat Ahmad Buhari Ahmad Bukhari Ahmad Hariri Ambarita, Petrus Alvin Peter Anis Azizah Anjar Hermadi Saputro Annisa Rahma Aryanti Astuti, Puput Puji Ayudya, Malika Aziza Bella Triyanti, Sinta Damar Nurwahyu Bima Deana Wahyuningrum Dela Ayu Fitria Dewi, Dea Puspa Elianasari Elianasari, Elianasari Fajri Ikhsan Fitri Nadiyah, Syakirah Hakiki, Salsabila Sofia Handayani, Kiki Yuli Hani Nurul Fadhilah Ika Rifqiawati Ina Indriana Ina Indriana Indah Puspita Sari Indah Puspita Sari, Indah Puspita Izzati, Aluna Monalaika Karen Erlangga Karima, Naura Putri Lia Nurliana M. Ganiadi Made Helen Susanti Mahardika, Aurellia Azzahra Margareth, Angelica Maryani, Yeyen Mentari, Corona Meri Yulvianti Meri Yulvianti Mufaza, Wahya Muhammad Farhan Muhammad Triyogo Adiwibowo Nieyan, Putri Ananda Nurbaiti, Siwi Nurrahmah, Salsabila Pebriyanti, Ine Petrus, Dhannydon Rahim, Audy Nasyiah Rahmadani, Sinta Salsabila, Keisya Yumna Saputra, Iwan Syahjok Shefia Dhiya Khansa Simatupang, Petrus Edison Siti Fadilla Suaedah Suaedah Syahjoko Saputra, Iwan Syaputra, Iwan Syahjoko Syarif Abdullah Tia Azzahra Putri Tifani Pardede Ullaya Syarifah Veni Putri Nurhayati Widya Ernayati Kosimaningrum Yayan Maryani Yazid Rukmayadi Yeyen Maryani Yeyen Maryani Yeyen Maryani Yeyen Maryani