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All Journal Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Jurnal Kebidanan Indonesia Avicenna : Journal of Health Research SENTRI: Jurnal Riset Ilmiah Jurnal Farmasetis Journal for Quality in Public Health Jurnal Farmasi Sains dan Teknologi
Yesi Ihdina Fityatal Hasanah
Sekolah Tinggi Ilmu Kesehatan Mamba’ul ‘Ulum Surakarta
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METAANALISIS COST-EFFECTIVE TELEMEDICINE DALAM MENANGANI MASALAH KESEHATAN JIWA: MEMENUHI TEKNOLOGI YANG BELUM TERCAPAI SETELAH PANDEMI COVID-19 Tri Atmojo, Joko; Pradana, Anggie; Kuntari, Saras; Noerlita Ningrum, Andriani; Tri Handayani, Rina; Widiyanto, Aris; Rejo, Rejo; Setyorini, Catur; Rahma Widyaningrum, Nova; Zamani, Ahmad; Nurhayati, Isnani; Dewi Lieskusumastuti, Anita; Puspitasary, Kiki; Nur Fauziah, Ani; Yuniarti, Tri; Sayekti Heni Sunaryanti, Sri; Iswahyuni, Sri; Ihdina Fityatal Hasanah, Yesi; Sabngatun, Sabngatun; Nurrochim, Nurrochim; Daryanto, Daryanto; Hanifah, Lilik; Maesaroh, Siti; Novitasari, Meliana; Indarto, Indarto; Karmadi, Karmadi; Nur Rokhmatun, Puji; Syauqi Mubarok, Ahmad; Anasulfalah, Hakim; Suparti, Sri; Rohmi, Rohmi; Febri Susanti, Rinandita; Hidayati, Anisa; Joko Yulianto, Dwi; Verasita, Prissy; Azmiardi, Akhmad; Rasyid Ridha, Achmad; Irawati, Dina; Triwibowo, Joko; Sindi Wardani, Galuh; Aditya, Mifta; Reza Kurnia, Febria; Eri Pramuja, Wanda; Ardia Pramesti, Risa; Setiawan Manurung, Budi; Puji Lestari, Apriliani; Auraldi Nansurya, Alga; Ernawati, Heni; Tri Darmayanti, Aquartuti; Ismail, Aem; Hanif, Ihsan; Maratul Munawar, Siti; Aqsyari, Rizki; Yuli Ayuningrum, Ika; Mirsanti, Faradilla
Avicenna : Journal of Health Research Vol 6, No 2 (2023): OKTOBER
Publisher : STIKES Mamba'ul 'Ulum Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36419/avicenna.v6i2.949

Abstract

Analisis Profil Metabolit Ekstrak Etanol Gracilaria verrucosa Menggunakan Liquid Chromatography–High Resolution Mass Spectrometry Ningrum, Andriani Noerlita; Hasanah, Yesi Ihdina Fityatal
SENTRI: Jurnal Riset Ilmiah Vol. 4 No. 11 (2025): SENTRI : Jurnal Riset Ilmiah, November 2025
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/sentri.v4i11.4771

Abstract

Gracilaria verrucosa is a red alga with promising potential as a source of bioactive metabolites. Previous studies have mainly reported antioxidant or antibacterial activity and total phenolic content without resolving specific molecular entities. This study aimed to generate a non-targeted LC–HRMS profile of semi-polar secondary metabolites from the ethanol extract of G. verrucosa and to annotate dominant ion features into defined chemical classes. Dried biomass was macerated with 96% ethanol and analysed using UHPLC–Orbitrap HRMS in Full MS/dd-MS² mode. After QC filtering, 325 ion features were detected; 51 could be annotated with Schymanski level 2–3 confidence into five classes: oxylipins/jasmonate derivatives, phytosterols, ionone-type apocarotenoids, phenolic–flavonoids, and carnitine-conjugated lipids. Representative candidates included jasmonic acid, 6-hydroxy-3-oxo-α-ionone, cholesteryl triol, flavonoid derivatives, and eicosadienoylcarnitine. These results indicate that the semi-polar metabolome of G. verrucosa is enriched in signalling-related oxylipins and sterols, antioxidant phenolic scaffolds, and acylcarnitines linked to energy metabolism, thereby providing a more mechanistic basis for its reported bioactivities. To our knowledge, this is the first comprehensive LC–HRMS-based metabolite map of Indonesian G. verrucosa, and it offers a chemically resolved framework to support subsequent fractionation, isolation, structural elucidation, and targeted pharmacological studies.
Co-Authors Adi Saputro, Endri Aditya, Mifta Ady Irawan Ahmad Rois Syujak Ahmad Syauqi Mubarok Ahmad Syauqi Mubarok Ahmad Zamani Ahmad Zamani Ahmad Zamani, Ahmad Akhmad Azmiardi Alga Auraldi Anasulfalah, Hakim Andriani Noerlita Ningrum Andriani Noerlita Ningrum Anggie Pradana Putri Anggie Pradana Putri Ani Nur Fauziah Anisa Hidayati Anita Dewi Lieskusumastuti Aqsyari, Rizki Aquartuti Tri Darmayanti Aquartuti Tri Darmayanti Aquartuti tri Darmayanti Aquartuti Tri Darmayanti Ardia Pramesti, Risa Auraldi Nansurya, Alga Baehaqi Budi Setiawan Manurung Catur Setyorini Catur Setyorini Daryanto Daryanto Daryanto Daryanto Dewi Arradini Dewi Lieskusumastuti, Anita Dina Irawati Dwi Joko Yulianto Dwi Joko Yuliyanto Dwi Lestari Endri Adi Saputra Eri Pramuja, Wanda Ernawati, Heni Etik Sulistyorini Eva Leny Alviani Febri Susanti, Rinandita Febria Reza Kurnia Galuh Sindi Wardani Galuh Sindi Wardhani Handayani, Rina Tri Hanif, Ihsan Hanifah, Lilik Heni Ernawati Heni Heni Ernawati Hidayati, Anisa Ika Yuli Ayuningrum Indah Wulandari, Dwi Indarto Indarto - Indarto Indarto Indarto Indarto Irfan Armanto Ismail, Aem Isnani Nurhayati Isnani Nurhayati Iswahyuni, Sri Joko Prayitno Joko Tri Atmojo Joko Triwibowo, Joko Joko Yulianto, Dwi Karmadi Karmadi Karmadi, Karmadi Khansa Azizah, Fara Kiki Puspitasary Kiki Puspitasary Kuntari, Saras Lilik Hanifah Lilik Hanifah Maratul Munawar, Siti Meliana Novitasari Mifta Aditya Miranda Juandrina, Shella Mirsanti, Faradilla Mubarok, Ahmad Syauqi Muhamad Yuli Kartiko Nabhani Nabhani Nabilla Perdinant Nasrul Sani Ndaru Syukma Putra Ningrum, Andriani Noerlita Noerlita Ningrum, Andriani Nova Rahma Widyaningrum Novitasari, Meliana Nur Fauziah, Ani Nur Rokhmatun, Puji Nurhayati, Isnani Nurrochim Nurrochim Nurrochim, Nurrochim Pradana Putri, Anggie Pradana, Anggie Puji Lestari, Apriliani Puji Nur Rokhmatun Puspitasary, Kiki Rahma Widyaningrum, Nova Rasyid Ridha, Achmad Ratna Wirawati Rejo Rejo Rejo Rejo Rejo, Rejo Reza Kurnia, Febria Rinandita Febri Susanti Rinandita Febri Susanti Rohmi Rohmi Rohmi, Rohmi Sabatun Sabatun Sabngatun, Sabngatun Sab’ngatun, Sab’ngatun Saras Kuntari Saras Kuntari SATRIYAS ILYAS Sayekti Heni Sunaryanti, Sri Selvia Anggitasari Setiawan Manurung, Budi Setyorini, Catur Sindi Wardani, Galuh Siti Maesaroh Siti Maesaroh Solly Aryza Sri Hartutik Sri Iswahyuni Sri Iswahyuni SRI LESTARI Sri Sayekti Heni Sunaryanti Sri Sayekti Heni Sunaryanti Sri Suparti Suciyati Suciyati, Suciyati Suminanto Suminanto Syauqi Mubarok, Ahmad Taniar, Bella Sinta Sheila Tatik Trisnowati Tio Guntur Prabowo Tri Atmojo, Joko Tri Darmayanti, Aquartuti Tri Handayani, Rina Tri Yuniarti Tri Yuniarti, Tri Ulin Nuha Verasita, Prissy Widiyanto, Aris