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All Journal Abdimas Jurnal Penelitian Pendidikan Rekayasa: Jurnal Penerapan Teknologi dan Pembelajaran Sainteknol : Jurnal Sains dan Teknologi Jurnal Kebidanan Dan Kesehatan Tradisional Journal of Biology Education Universa Medicina Unnes Science Education Journal Biosaintifika: Journal of Biology & Biology Education Jurnal Pemberdayaan: Publikasi Hasil Pengabdian Kepada Masyarakat Jurnal Pembelajaran dan Biologi Nukleus Jurnal ABDINUS : Jurnal Pengabdian Nusantara Abdimasku : Jurnal Pengabdian Masyarakat ABDIMAS Jurnal Pengabdian Kepada Masyarakat Life Science Prosiding Seminar Nasional Biologi Unnes Science Education Journal Biosaintifika: Journal of Biology & Biology Education Bioeksperimen Jurnal Ilmu Kesehatan Masyarakat (The Public Health Science Journal) Indonesian Journal of Mathematics and Natural Sciences Life Science
Wulan Christijanti
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Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health Social Sciences Other

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Penerapan Pertanian Berkelanjutan Berbasis Produk Pertanian Lokal di Desa Sendangsari, Kecamatan Bener, Kabupaten Purworejo Susanti, R.; Christijanti, Wulan; Kusuma, Putri Patria; Sasi, Fitri Arum; Suryonegoro, Bayu Murti; Wijaya, Ifan Badra
Prosiding Seminar Nasional Biologi Vol. 13 (2025)
Publisher : Prosiding Seminar Nasional Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Desa Sendangsari terletak di Kecamatan Bener, Kabupaten Purworejo, Provinsi Jawa Tengah memiliki lahan yang cukup luas, digunakan sebagai lahan sawah seluas 125.000 Ha, lahan perkebunan seluas 25.000 Ha, dan lahan ladang seluas 77.000 Ha. Permasalahan utama yang dihadapi mitra adalah keterbatasan pengetahuan dan keterampilan sumber daya petani, sarana dan prasarana yang belum memadai, serta inkusivitas penerapan pertanian yang belum berkelanjutan. Metode pengabdian yang diterapkan adalah sosialisasi/penyuluhan pentingnya pertanian berkelanjutan, praktek penanaman tanaman obat keluarga dan tanaman buah, praktek pemanfaatan limbah organik dengan membuat pupuk kompos, pupuk organik cair dan ecoenzyme, serta pelatihan pengemasan dan pemasaran produk pertanian menggunakan berbagai platform. Hasil pengabdian menunjukkan bahwa peserta mampu membuat pupuk organik (kompos, pupuk organik cair, dan ecoenzyme), 100% mampu memahami jenis-jenis dan manfaat tanaman TOGA dan tanaman buah, 95,4% peserta memahami tentang jenis-jenis, cara pembuatan dan penggunaan pupuk organik, dan 91,5% peserta memahami strategi pemasaran produk pertanian. Disimpulkan, kegiatan pengabdian mampu mempraktekkan pertanian berkelanjutan melalui pembuatan dan penggunaan pupuk organik untuk tanaman buah dan tanaman obat. Konsep strategi pemasaran juga telah dipahami oleh peserta namun belum sepenuhnya dapat diimplementasikan.
The Effect of Tamarind Fruit Nanoparticles (Tamarindus indica) on the Sperm Quality of Hyperglycemic Rats Bagus Hammam Falah; Wulan Christijanti; Nugrahaningsih WH; R. Susanti
Life Science Vol. 14 No. 2 (2025): November 2025
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/unnesjlifesci.v14.i2.24064

Abstract

Hyperglycemia is an increase in glucose levels in the blood. This condition can trigger glucose autooxidation which can produce free radicals. Free radicals can cause damage to male reproductive organs and quality. Tamarind fruit has a high flavonoid which has the potential as an antioxidant. This study aims to analyze the effect of tamarind fruit nanoparticles on spermatozoa quality in hyperglycemic rats. This study is experimental with Post-Test Control Group Design. A sample of 15 male Wistar rats were induced by alloxan and then divided into three groups, namely the control group, tamarind fruit nanoparticles with a dose of 30 mg/KgBB (NP1) and 60 mg/KgBB (NP2) for 28 days. Sperm quality was observed with parameters of concentration, motility and viability. The data were analyzed using One Way ANOVA and LSD. The results of the Anova test showed that tamarind nanoparticle treatment could significantly improve sperm quality (P<0.05). The LSD test showed that the concentration, motility and viability of sperm in group (K) were significantly different from groups NP1 and NP2. The highest to lowest average sperm concentration in sequence was in groups NP2 (49.60x106±6.06x106), NP1 (41.60x106±7.40x106) and K (20.80x106±7.56x106). The highest to lowest average percentage of sperm motility in sequence was in groups NP2 (82.20±9.75), NP1 (74.00±4.74), K (47.20±10.66). The highest to lowest average percentage of sperm viability in sequence was in the NP2 group (76.80±4.49), NP1 (72.20±7.12), K (31.60±7.89). The conclusion of this study is that tamarind nanoparticles have an effect on improving sperm quality in hyperglycemic rats.
Pemberdayaan Ibu-Ibu PKK dalam Pembuatan Pupuk Organik untuk Mendukung Urban Farming di Kelurahan Kalirejo, Kecamatan Gunungpati, Kota Semarang Lina Herlina; Pramesti Dewi; Wulan Christijanti; Talitha Widiatningrum
ABDIMAS Jurnal Pengabdian Kepada Masyarakat Vol. 6 No. 2 (2025): ABDIMAS JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : Research and Community Service INSTITUT TEKNOLOGI DAN BISNIS KALBIS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53008/qe2bsj27

Abstract

Program pengabdian kepada masyarakat ini bertujuan untuk memberdayakan ibu-ibu anggota PKK di RT 03/RW 05, pada pembuatan pupuk organik dari limbah rumah tangga. Pelatihan ini dilakukan guna mendorong peningkatan pemahaman serta keterampilan ibu-ibu PKK dalam pembuatan pupuk organik berkualitas secara mandiri. Selain itu program ini bertujuan  dalam mendorong praktik urban farming di lingkungan perkotaan, yang berkontribusi pada ketahanan pangan lokal, pengelolaan sampah organik yang lebih baik, dan menciptakan lingkungan yang lebih hijau dan sehat. Metode yang dipergunakan pada program ini mencakup sosialisasi, pelatihan pembuatan pupuk organic, serta pendampingan berkelanjutan. Hasil dari program ini mengindikasikan peningkatan pengetahuan serta keterampilan ibu-ibu PKK terkait pembuatan pupuk organik. Selain itu, inisiatif urban farming di lingkungan tempat tinggal peserta juga mengalami peningkatan, ditandai dengan pemanfaatan pupuk organik hasil pelatihan pada tanaman yang mereka budidayakan. Kegiatan ini menunjukkan  bahwa pemberdayaan masyarakat melalui pelatihan keterampilan praktis dapat menjadi solusi efektif dalam mendukung pertanian perkotaan yang berkelanjutan.
Pengaruh Nanopartikel Ekstrak Asam Jawa terhadap Perubahan Morfologi dan Histologi Testis Tikus Hiperglikemia Christijanti, Wulan; R. Susanti; Marianti, Aditya; Widiyaningrum, Kartika
Indonesian Journal of Mathematics and Natural Sciences Vol. 48 No. 2 (2025): Vol. 48 No. 2 (2025): Volume 48 Nomor 2 October 2025
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/jm.v48i2.37045

Abstract

Hiperglikemia dapat menimbulkan kerusakan jaringan serta menimbulkan berbagai komplikasi, seperti neuropati, nefropati, retinopati, dan gangguan pada sistem reproduksi. Asam jawa mampu menurunkan kadar gula darah sekaligus mengurangi radikal bebas menunjukkan potensi efek pencegahan kerusakan testis. Ukuran partikel yang sangat kecil mampu meningkatkan distribusi, penyerapan  dan interaksi lebih efektif dengan target biologis. Tujuan penelitian adalah mengkaji pengaruh nanopartikel ekstrak asam jawa pada testis secara morfologi dan histologis tikus pada kondisi hiperglikemia. Tikus diinduksi aloksan monohidrat 150 mg/kg berat badan intraperitoneal. Kriteria hiperglikmeia dengan kadar glukosa > 120 mg/dl setelah 3 hari induksi. Tikus dibagi menjadi Kontrol hiperglikemia (K), vitamin C 150 mg/kg (PC) ,  glibenklamid 5 mg/kg (PG) dan nanopartikel asam jawa 30 mg (PB 1) serta 60 mg/kg (PB 2) per oral selama 4 minggu. Variabel yang diamati berupa berat, panjang, diameter dan derajat spermatogenesis testis. Data dianalisis dengan Anova dan uji lanjut Beda Nyata Terkecil. Hasil penelitian menunjukkan perlakuan mempengaruhi variabel dan  memberikan perbedaan signifikan pada berat dan derajat sepermatogenesis p<0,05, namun tidak signifikan untuk panjang dan diameter testis. Simpulan penelitian adalah nanopartikel asam jawa berpengaruh terhadap berat dan derajat spermatogenesis tikus hiperglikemia.
Effects of Green Tea Extract (Camellia sinensis L.) on Blood Biochemical Parameters in Paracetamol-Induced Wistar Rats Galih, Damar; Indriyani, Indriyani; Septiningtyas, Sinta Dwi; Christijanti, Wulan; Susanti, R.; Marianti, Aditya
Jurnal Kebidanan dan Kesehatan Tradisional Jurnal Kebidanan dan Kesehatan Tradisional Volume 11 Number 1 Year 2026
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37341/jkkt.v11i1.650

Abstract

Background: Paracetamol is one of the analgesics and antipyretics that are widely traded freely, so it is possible that the use is not according to the recommended dose and consumption time. This can trigger liver damage and changes in blood biochemistry. Green tea has components such as antioxidants, anti-inflammatories, and hepatoprotectors. The study aimed to analyze the effect of green tea extract on the blood biochemistry of rats induced by paracetamol. Methods: Laboratory experimental research with the Post-Test Control Group Design method, using 25 male Wistar rats, applying random sampling. Twenty-five rats were divided into 5 groups: K- (control), K+ (positive control), and treatment groups with green tea extract, respectively 175 mg (T1), 350 mg (T2), and 700 mg/kg bw (T3) for 24 days. The treatment group and K+ received paracetamol 600 mg/kg bw on the 14th day for 10 days, and green tea extract was still given. Data, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), triglycerides (TG), total cholesterol, and leukocyte counts, were analysed using ANOVA and the Least Significant Difference (LSD) test. Results: GTE significantly (p-value <0.05) reduced leukocytes and AST, but inadequate paracetamol induction failed to elevate ALT and lipids, masking GTE’s measurable impact on those specific biochemical parameters. Conclusion: Providing green tea extract was effective in declining the number of leucocytes and AST levels. The study concluded that green tea extract has the potential to influence the biochemical profile of rats induced by paracetamol. Further research is needed regarding the dose and period of administration and exposure.
Ethanolic Extract of Tamarindus indica Leaves Lowers Total Cholesterol, Triglycerides, and HDL but Without Affecting LDL in Hyperlipidemic Rats Susiloningsih, Tri; Christijanti, Wulan; Marianti, Aditya; WH, Nugrahaningsih
Bioeksperimen: Jurnal Penelitian Biologi September 2025
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/bioeksperimen.v11i2.12103

Abstract

Hyperlipidaemia is a condition of increased lipid levels, especially cholesterol, triglycerides, LDL and an abnormal decrease in HDL in the blood. Tamarind leaves contain flavonoid and quercetin compounds that have the ability as antihyperlipidemia agents. The purpose of this study was to examine the effect of tamarind leaf ethanol extract on the lipid profile of hyperlipidaemia rats. Samples of 16 male Wistar rats were divided into 4 groups; Control group and the tamarind leaf ethanol extract treatment group was divided into 3, namely P1 350 mg/kgBB, P2 500 mg/kgBB, and P3 650 mg/kgBB. All rats were given lard 3 mL/head/day for 2 weeks. In weeks 3 and 4, rats were given extract of Tamarindus indica leaves and 2 hours interval was given lard. The data obtained were statistically analysed using one-way ANOVA and the Least Significant Difference (LSD) test at the 95% confidence level. In this study, HDL levels decreased along with reductions in total cholesterol and triglycerides, but had no effect in reducing LDL levels. Reduced cholesterol synthesis limits substrate availability for HDL formation, resulting in proportional decreases in HDL-C. The conclusion of this study is that tamarind leaf ethanol extract has an effect in reducing lipid profile levels.
Potential of butterfly pea (Clitoria ternatea) nanoherbal on spermatozoa quality in hyperglycemic rats Putri, Komala Amelia; Christijanti, Wulan; Marianti, Aditya
Bioeksperimen: Jurnal Penelitian Biologi March 2026
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/bioeksperimen.v12i1.15239

Abstract

Hyperglycemia is a condition characterized by elevated blood glucose levels that induce free radical formation, leading to reduced spermatozoa quality. Butterfly pea (Clitoria ternatea) contains antioxidant compounds and is formulated as a nanoherbal to enhance bioavailability. This study aimed to evaluate the potential of butterfly pea nanoherbal in improving spermatozoa quality in hyperglycemic rats. This experimental study employed a post-test only control group design using 25 male Wistar rats divided into a healthy control group and hyperglycemic groups induced by alloxan (125 mg/kg BW). The hyperglycemic groups consisted of a metformin control (400 mg/kg BW) and butterfly pea nanoherbal treatment groups at doses of 12.5, 25, and 50 mg/kg BW administered for 28 days. Data were analyzed using One-Way ANOVA followed by the Least Significant Difference (LSD) post hoc test. The results showed that spermatozoa concentration in the healthy control group differed significantly from the positive control, P1, and P2 groups (p<0.05), but not from the P3 group. Spermatozoa motility and viability also showed significant differences among groups (p<0.05). It can be concluded that butterfly pea flower nanoherbal significantly improves spermatozoa quality in hyperglycemic rats.
Effectiveness of Clitoria ternatea L. Nanoherbal on Blood Glucose and Malondialdehyde Levels of Hyperglycemic Rats Buana, Cahya; Christijanti, Wulan; Yuniastuti, Ari
JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS Vol 12, No 1: Jurnal Pembelajaran Dan Biologi Nukleus March 2026
Publisher : Universitas Labuhanbatu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36987/jpbn.v12i1.8874

Abstract

Background: Hyperglycemia induces excessive production of reactive oxygen species (ROS), leading to oxidative stress and lipid peroxidation characterized by increased malondialdehyde (MDA) levels. This study evaluated the effectiveness of butterfly pea flower nanoherbal formulated as alginate-based nanoparticles using the ionic gelation method in reducing blood glucose and MDA levels in hyperglycemic rats. Methodology: 25 male Wistar rats (Rattus norvegicus) were divided into five groups: normal control (NC), metformin control (MC), and three nanoherbal treatment groups (NT1, NT2, and NT3) receiving doses of 12.5, 25, and 50 mg/kg body weight (BW), respectively. Hyperglycemia was induced by a single intraperitoneal injection of alloxan monohydrate (125 mg/kg BW). Blood glucose was measured on days 1, 14, and 28, while MDA levels were analyzed on day 28 using the TBARS method. The analysis of blood glucose levels was conducted using a Repeated Measures Two-Way ANOVA followed by a Bonferroni post hoc test, while MDA data were evaluated through a One-Way ANOVA with Duncan’s multiple range test (p < 0.05). Findings: A significant, dose-dependent reduction in blood glucose levels was observed following nanoherbal treatment. The NT3 group (50 mg/kg BW) showed the greatest reduction, with mean glucose decreasing from 471.4 ± 142.00 mg/dL on day 1 to 146.4 ± 68.58 mg/dL on day 28. MDA levels also differed significantly, with NT3 showing 2.84 ± 0.19 nmol/mL, indicating lower oxidative stress. Contributions: These findings indicate that alginate-based butterfly pea nanoherbal can reduce blood glucose and MDA levels in hyperglycemic rats, suggesting its potential role in improving glycemic control and reducing oxidative stress under hyperglycemic conditions
Co-Authors - Suprihatin, - Aditya Marianti Alfiatun N, Alfiatun Amanatul Munawaroh, Amanatul Andreas Priyono Budi Prasetyo Anggoro, Naufal Sebastian Anisa Dewi Sri Puspitasari Ari Yuniastuti Arya Iswara Arya Iswara Aulia, Maliqa Ayu Etna Ningtyas, Ayu Etna Azkiyah, Nimas Catur Badingatus Sholihah Bagus Hammam Falah Cahya Buana Damar Galih Dewi Mustikaningtyas Dimarti, Safira Chaerani Dimarti, Safira Chairani Edward Louis Krey Eling Purwantoyo Ely Rudyatmi, Ely Endah Peniati Falistina, Amna Fifti Istiklaili, Fifti Fitri Arum Sasi, Fitri Arum Fonda, Sarah Shabrina Galih, Damar Hammam, Bagus Ibnul Mubarok Indriyani Indriyani Jabar, Muhammad Abdul Kartika Widyaningrum Kikie Septiyana, Kikie Kusuma, Putri Patria Kusuma, Zeni Herawati Laraswati, Vivi Anggraeni Lina Herlina Lisdiana Lisdiana M.A. Sunny Maridah Nurjanah, Maridah Martien Herna Susanti Maulana, Silvia Faori Mighfar Khamida, Mighfar Mirtaati Na’ima Mohamed, Mohd Salim Bin Mu’afy, Faizal Daffa Na’ima, Mirtaati Nana Kariada Trimartuti Ning Setiati Nisa', Lailatun Nisa' Nissa, Ma’isyatun Noor Aini Habibah Nugrahaningsih WH Nugrahaningsih WH, Nugrahaningsih Nugrahaningsih, WH Nur Rahayu Utami Nur Rahayu Utami Nuryanti, Novi Pauline, Maretha Putri Pramesti Dewi Priyanto, Yudi Purnamaningrum, Sisilia Prita Dewi Putri, Komala Amelia R Susanti R. Susanti R. Susanti R. Susanti Rakainsa, Senda Kartika Ramadhanti, Shifa Ramasamy, Sujatha Rismanika Anggraeni, Rismanika Rizki Raharyu Noviami, Rizki Raharyu Rizki Raharyu, Rizki Sasabila Mumtaz Sekar Dwi Ardianti Senda Kartika Rakainsa Septiningtyas, Sinta Dwi Sholihah, Badingatus Sigit Saptono Siti Harnina Bintari Siti Qomariah, Siti Sriyadi , Sriyadi Sriyadi Sriyadi, Sriyadi Stephani Diah Pamelasari, Stephani Diah Sumad Sumad Sumad Sumad, Sumad Supriyanto - Suryonegoro, Bayu Murti Susiloningsih, Tri Talitha Widiatningrum Tsaniyah, Nurotun Najmatus Udin Ahmad Syahri, Udin Ahmad Wardani, Agata Iswiana Diah Widiyaningrum, Kartika Widyaningrum, Kartika Wijaya, Ifan Badra Wiwi Isnaeni Woro Sumarni Yudi Priyanto Zaenafree, Intan