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Buih, Putri Helena Junjung
Universitas Lambung Mangkurat
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Studi Perbandingan Antara Maserasi dan Accelerated Solvent Extraction (ASE) terhadap Hasil Ekstrak Daun Kalangkala (Litsea angulata) Nabila Hadiah Akbar; Putri Helena Junjung Buih; Khoirunnisa Muslimawati; Aditya Maulana Perdana Putra; Adhindha Amalia; Dhea Juliana Putri
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1305

Abstract

Kalangkala (Litsea angulata) is an endemic plant of Kalimantan that has long been used in local traditional medicine to manage various health conditions. Phytochemical reports indicate that Kalangkala contains diverse secondary metabolites, including phenolics, flavonoids, alkaloids, tannins, saponins, terpenoids, steroids, and carotenoids. Therefore, selecting an appropriate extraction method is essential to maximize metabolite recovery while minimizing degradation. This experimental study compared the extraction yield of Kalangkala leaf extract obtained using maceration and ASE (Accelerated Solvent Extraction) methods. Each method was performed in three replicates and the percentage yield was calculated. Maceration produced yields of 2.10-2.18%, whereas ASE produced higher yields of 13.25-14.01%. the mean yield of maceration was 2.14 ± 0.04% (95% Cl: 2.04-2.24), while ASE achieved 13.64 ± 0.38% (95%Cl: 12.69-14.58). A two-tailed Welch’s t-test confirmed a statistically significant difference between methods (p = 0.00032), with a mean difference of 11.49% (95% Cl: 10.56-12.42). In conclusion, ASE provided a higher extraction yield than maceration under the conditions evaluated in this study.
Co-Authors Achmad Ramadhanna’il Rasjava Adhindha Amalia Agustina, Ni Kadek Ayu Akbar, Nabila Hadiah Anna Khumaira Sari Ariranur Haniffadli Arnida Arnida Aulia Rhamdani Arfan Ayulia Dwi Sandi, Dita Catherina Adeline Kurniawan Deni Setiawan Dhea Juliana Putri Dyah Ayu Pramoda Wardani Fadlilaturrahmah Fadlilaturrahmah, Fadlilaturrahmah Firdarima Salsabila Hayatun Izma Indah Maharati Zoan Izma, Hayatun Khoirunnisa Muslimawati Liling Triyasmono Luthfia Azzahra Mahfuzatul Ajmi Malahayati, Siti Muhammad Ikhwan Rizki Muhammad Itqan Mazdadi Nadya Putri Auliya Serawaidi Naila Azizah Nanda Hesti Rahmawati Nazhipah Isnani Normaidah, Normaidah Nur Mahdi Okta Muthia Sari Putra, Aditya Maulana Perdana Rahmatullah, Satrio Wibowo Ratnapuri, Prima Happy Samsul Hadi Sari, Fitri Novita Siti Najwa Sutomo Sutomo Syahrul Yaiis Abdul Rahman Taufik Muhammad Fakih Yuniarti Suryatinah