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Journal : THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST

Pengaruh Ekstrak Mengkudu (Morinda citrifolia) Terhadap Penurunan Tekanan Darah Pada Tikus Putih Wistar Jantan Dengan Hipertensi Pipit Festi W
THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Vol 3, No 1 (2020): The Journal of Muhammadiyah Medical Laboratory Technologist
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (401.577 KB) | DOI: 10.30651/jmlt.v3i1.4630

Abstract

Hypertension is one of the most important causes of early death because it is closely related to the risk of cardiovascular disease. The prevalence of hypertension continues to increase with lifestyle changes. Non-pharmacological management is an alternative in the treatment of hypertension, one of which is complementary therapy by consuming herbal ingredients. The purpose of this study was to determine the effect of noni extract on reducing blood pressure in male  Wistar experimental-rats.The research design used was pre experimental design. One group pre-test post test design with purposive sampling technique. Number of samples were 16 male Wistar experimental-rats . The instrument in this study was the observation sheet and blood pressure measurement for taicap blod pressure. Statistical test analysis using Wilcoxon test.The results showed blood pressure before being given noni extract, cystolic pressure 150.93 mmHg, diastole pressure 112.87 mmHg. After administration of noni extract average blood pressure systole: 110,625 mmHg, diastole blood pressure average 85,125 mmHg Wilcoxon statistical test results showed that p = 0,000 <a = 0.05 showed a decrease in blood pressure before and after giving of noni extractThe conclusion from the study showed that there was an effect of noni extract on reducing blood pressure in hypertensive male Wistar experimental-mouse. Development of natural ingredients in the management of non-pharmacological hypertension needs to be done at the dose and effectiveness.                      Keywords: Hypertension, Noni extract, white rat. 
PENGARUH EKSTRAK BAWANG HITAM TERHADAP PENURUNAN KADAR GLUKOSA DARAH PADA MENCIT Pipit Festi W
THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Vol 4, No 1 (2021): The Journal of Muhammadiyah Medical Laboratory Technologist
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jmlt.v4i1.7269

Abstract

 Administration of oral hypoglycemic drugs and insulin is one of the most common pharmacological treatments given to people with diabetes mellitus. This treatment is carried out in the long term so that it causes side effects and is carried out continuously so that it will affect the financial condition of the diabetes mellitus patient. The purpose of this study was to determine the effect of black garlic extract on decreasing blood glucose levels in mice (mus musculus). This study uses the design of True Experimental design (pretest-posttest with control group design). The population is mice in Pusvetma Surabaya. Sampling method uses Non Probability Sampling Purposive Sampling type. Samples taken were 30 mice consisting of 15 intervention groups and 15 control groups. Data was collected using observation sheets, then analyzed using Independent sample t test and Dependent sample t test with a significance level of 5 0.05. The results showed: Using the test Independent sample T test obtained a significance value ρ = 0,000  It can be concluded that there is an effect of black onion extract to reduce blood glucose levels in mice. In the paired t-test test in the treatment group showed ρ = 0,000  that there were differences in blood glucose levels before being given extracts of garlic and after being given intervention. It is expected that black garlic can be used as an alternative medicine to reduce blood glucose levels.Keyword : Ekstrak of black garlic, Blood sugar levels, mus musculus
THE EFFECT OF TOMAN (Chana Micropetes) EXTRACT ON THE IMPROVEMENT OF ALBUMIN LEVELS IN MENCIT/MICE (Mus musculus) Pipit Festi W
THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Vol 3, No 2 (2020): The Journal of Muhammadiyah Medical Laboratory Technologist
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jmlt.v3i2.6047

Abstract

Hypoalbuminemia is a condition in which albumin levels are less than 3.8 g / dl. Management of hypoalbumin can be done on a  high high in protein such as toman fish extract (Chana Micropetes). Toman fish extract contains globular protein which can be used as an alternative diet in increasing albumin levels. The purpose of this study was to determine the effect of toman fish extract on increasing albumin levels in mencit (Mus musculus).               This research is an experimental research design with Pretest-Posttest Control Group Design. Samples using Mus musculus with the criteria of male sex, body weight 25-40 grm and 2 months old. The number of samples consisted of 32 animals consisting of 2 groups, 16 control groups and 16 treatment groups. Intervention by giving toman fish extract for 14 days. Research instruments, albumin levels and observation sheets. Data were tested statistically with Independent Sample t Test.               The results, this study showed the average value of albumin levels was 5.60 gr / dl in the treatment group so that an increase in albumin levels. There was a significant effect (p = 0,000 <α = 0.05) between the administration of toman fish extract to the increase in albumin levels in mencit (Mus Muculus).               Conclusion, giving toman fish extract can increase albumin levels in mencit. So that toman fish extract can be used as a high-protein alternative diet for hypoalbumin sufferers.Keywords: hypoalbumin, toman fish, (Chana Micropetes).