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All Journal Pharmaciana: Jurnal Kefarmasian Pharmacon IDJP (Indonesian Journal of Pharmaceutics) Jurnal Fitofarmaka Indonesia FITOFARMAKA: Jurnal Ilmiah Farmasi EKOLOGIA : Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup Molekul: Jurnal Ilmiah Kimia JFIOnline Jurnal Abdimas Madani dan Lestari (JAMALI) Jurnal Pusat Studi Pendidikan Rakyat (PUSDIKRA) JURNAL AGROINDUSTRI HALAL Pharmaceutical Sciences and Research (PSR) Jurnal Sosial dan Sains Kenduri: Jurnal Pengabdian Dan Pemberdayaan Masyarakat Journal of Tropical Pharmacy and Chemistry Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) Jurnal Pengabdian Masyarakat Inovatif Jurnal Pengabdian Masyarakat Inovatif
Sri Wardatun
Program Studi Farmasi Universitas Pakuan
Agriculture, Biological Sciences & Forestry Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Journal : Pharmacon

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Antioxidant Activity of the Herbal Combination of Black Cumin (Nigella sativa L.) with Soursop Leaves (Annona muricata L.) OR Celery (Apium graveolens L.) Wardatun, Sri; Sofihidayat, Trirakhma; Noorlaela, Ella; Agustin, Vina
Pharmacon: Jurnal Farmasi Indonesia Vol 21, Special Issue 1, 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i0.23466

Abstract

Excessive free radicals in the body can cause various degenerative diseases; antioxidants can reduce the impact of free radical injury. Several plants have been tested for antioxidant activity, including black cumin (Nigella sativa L.), soursop leaves (Annona muricata L.), and celery (Apium graveolens L.). Black cumin is easy to find in several finished products on the market in Indonesia alone or in combination with other ingredients, including soursop leaves and celery. This study aimed to explore the interaction of laboratory-prepared and commercial combinations of black cumin extract with soursop or celery extract. The antioxidant activity of each extract was determined, and the combined antioxidant activity was calculated. The interactions of the combinations were identified based on the interaction factor values. The antioxidant activities were measured using DPPH (2,2-diphenyl-1-picrylhydrazyl) reagent. The results revealed nearly all exhibited strong antioxidant activity, except for black cumin–based commercial combination preparations, which demonstrated weak had antioxidant activity. Moreover, all combination extracts—laboratory made or commercial—had an IF value of 1. Conclusion: The combination of black cumin extract with soursop or celery leaf extract resulted in an antagonistic effect (IF 1) on the antioxidant ability.
Co-Authors - Affandi - Moerfiah - Prasetyorini Achmad Noerkhaerin Putra Aditya Aprizayansyah Afifah, Nida Agustin, VIna Ahyar, Akmal Zainul Akhmad Endang Zainal Hasan Almunawaroh, Zahra Alvia Suraya Amalina, Dhaifa Ghaisani Rizkia Andi Fauzi Aprizayansyah, Aditya Asri Wulandari Aulia Fitriani Bina Lohita Sari D Prasetyorini E Mulyati Effendi, E Mulyati Erni Rustiani Fadlina Chany Saputri fauzi, andi Fitri Atika suri Herman Suryadi Ike Yulia Indah Puspita Dewi, Anggy Ismail Nasution Juhroh, Juju Lakum, Lakum Lia Puspita Sari Mahyuni, Siti Malatabu, Shapira Mera Mardiamah, Suci Marpaung, Juwita Rosvenia Mira Miranti MOERFIAH . Moerfiah Moerfiah Mun'im, Abdul Nhestricia, Nhadira Nina Herlina Nining, Euis Noorlaela, Ella Noorwati Sutandyo Novi Fajar Utami Oom Komala Opi Damahyanti Padhilah, Prasti Restu Prasetyorini Prasetyorini Purnamasari, Anita Putra Setiawan Randiansyah, Randiansyah Safira, Ukhradiya Maharaniq Sofihidayat, Trirakhma Sofihidayati, Trirakhma Sofihidayati, Trirakhma Sunarya, M. Rustan suri, Fitri Atika Trirakhma Sofihidayati Wildan Aristyo Yahdiana Harahap Yulia, Ike Zaldy Rusli Zaldy Rusli