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All Journal Jurnal Ilmiah Farmasi Journal of Biomedicine and Translational Research Biota Jurnal Sains dan Teknologi Pangan Science and Technology Indonesia Martabe : Jurnal Pengabdian Kepada Masyarakat Hearty : Jurnal Kesehatan Masyarakat Jurnal Kreativitas PKM Jurnal Abdimas PHB : Jurnal Pengabdian Masyarakat Progresif Humanis Brainstorming Jurnal Abdimas Mahakam Majalah Farmasetika CERATA Jurnal Ilmu Farmasi Jurnal Pembelajaran dan Biologi Nukleus Jurnal Ners Jurnal Riset Kefarmasian Indonesia HSG (Health Science Growth) Journal Janaka : Jurnal Pengabdian Masyarakat Lumbung Farmasi : Jurnal Ilmu Kefarmasian Indobiosains EEICT (Electric, Electronic, Instrumentation, Control, Telecommunication) Jurnal Ilmiah Wahana Pendidikan Jurnal Pijar MIPA Jurnal Farmasetis Parapemikir Jurnal Ilmiah Farmasi Media Farmasi CERATA Jurnal Sains dan Kesehatan Jurnal Bioteknologi & Biosains Indonesia (JBBI)
Ahsanal Kasasiah
Universitas Singaperbangsa Karawang
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Journal : Hearty : Jurnal Kesehatan Masyarakat

 1 
UTILIZATION OF CHIMERIC ANTIGEN RECEPTOR-T (CAR-T) CELL THERAPY AS AN INNOVATIVE THERAPY FOR NON-SMALL LUNG CANCER (NSLC) Rusdiawan, Fairuz Octora Aulia; Kasasiah, Ahsanal
HEARTY Vol 13 No 3 (2025): JUNI
Publisher : Fakultas Ilmu Kesehatan, Universitas Ibn Khaldun, Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32832/hearty.v13i3.19878

Abstract

Non-Small Lung Cancer is one of the types of lung cancer with the highest prevalence in Indonesia. So that treatment is needed in an effort to reduce the prevalence rate. Chimeric Antigen Receptor-T (CAR-T) cell therapy is known to have the potential to be an alternative treatment for these types of cancer cells. This research is made with the hope that in the future this research can be further developed by researchers, especially in Indonesia. This literature study was made using the Systematic Literature Review (SLR) design to determine the effectiveness of CAR-T cell therapy targeted at several different genes and tested on mouse xenograft models. The journals used were obtained with a publication range of 2014-2024 and 7 journals were selected based on the results of inclusion and exclusion. Based on the results of the article review, it is known that CAR-T cell therapy targeting genes has good antitumor activity efficacy obtained from the test results by measuring the volume and weight of tumors in mouse xenograft models using a caliper and Bioluminescence Imaging (BLI) irradiation method.
Co-Authors Adi Pancoro Adinda Christianti Suparno Adrian Hartanto, Adrian Aliya Azkia Zahra Anisa Aula Rahma Annajla, Fathina Asman Hitopik Astika, Eriyanti Cartas Cartas Dadang Sumardi Damara, Dandy Satria Daniel Joko Wahyono Devi - Ratnasari Devi Ratnasari Devi Ratnasari Dinda Nugrahan Eriyanti Astika Fika Setra Rikantara Fikri, Al Mukhlas Fuji Ayu Diniarti Hasna, Vina Luthfiana Hendiana, Siti Nurazizah Aghisna Hermosaningtyas, Anastasia Aliesa Hitopik, Asman Indah Laily Indah Laily Hilmi Indratno, Saarah Hamidah Asmara insani abadi bangsa Irwansyah, Silvana Lestari Jekmal Malau Jekmal Malau Lely Sulfiani Saula Lestari, Agatha Nabilla Mally G Sholih Mally Ghinan Sholih Manalu, Rosario Trijuliamos Marsah Rahmawati Utami Meilani, Nanda Diva Meliana Sari, Meliana Muhammad Naufal Nurhadi Hidayat Muhareva Raekiansyah Nabila Rubinadzari Nur Khafipah Nur Komala Fitri Nuraeni Putri Nurhadis, Nurhadis Priscinya Christiana Debora Putri, Meisya Diffa Amalia Rahma, Anisa Aula Rahmasari, Ratika Ratnasari, Devi Rivandia Listi Rizky Abdul Majid Rosa Arum Rusdiawan, Fairuz Octora Aulia Saarah Hamidah Asmara Indratno Salman Salman Saryono Sekar Andjung Tresnawati Septi, Annisa Frastica Septiani, Dia Sholih, Mally Ghinan Siboro, Dewi Pratiwi Purba Siti Rohmah Sophy Wulandari Sudarjat, Hadi Syeli Syawaliyah Urbaningrum, Lestari Mahardika Vesara Ardhe Gatera Zahra, Aliya Azkia Zahro, Aurora Fatimatuz