Article Per Year (5 Year)
p-Index From 2020 - 2025
7.432
P-Index
This Author published in this journals
All Journal Journal of Food and Pharmaceutical Science Jurnal Ilmiah Farmasi Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Indonesian Journal of Cancer Chemoprevention Pharmacon Pharmascience Berkala Kedokteran Jurnal Surya Medika PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Indonesian Journal of Chemical Analysis (IJCA) Journal of Midwifery and Nursing Jurnal Jamu Indonesia Fullerene Journal of Chemistry CERATA Jurnal Ilmu Farmasi JURNAL PENDIDIKAN MIPA Pharmacoscript Jurnal Farmamedika (Pharmamedica Journal) Jurnal Jejaring Matematika dan Sains Science Midwifery International Journal of Clinical Inventions and Medical Sciences (IJCIMS) Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Sabdariffarma: Jurnal Ilmiah Farmasi Indonesia Berdaya Hydrogen: Jurnal Kependidikan Kimia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Pijar MIPA Jurnal Ilmiah Berkala: Sains dan Terapan Kimia Journal of Pharmaceutical Care and Sciences Jurnal Farmasi Sains dan Praktis Jurnal Bakti Untuk Negeri Gunung Djati Conference Series Jurnal Nusantara Berbakti Jurnal Pengabdian Masyarakat Indonesia Sejahtera Jurnal Farmasi SYIFA Journal of Food and Pharmaceutical Sciences CERATA Jurnal Pengabdian Masyarakat Panacea Jurnal Sains dan Kesehatan
Samsul Hadi
ULM
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

Published : 57 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search
Journal : Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan

 1 
SKRINING SENYAWA INHIBITOR H2 DARI KAYU MANIS (Cinnamomum verum J.Presl) Samsul Hadi; Diah Aulia Rosanti; Desiya Ramayanti Azhara; Kunti Nastiti
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (291.519 KB) | DOI: 10.36387/jiis.v6i2.663

Abstract

Digestive tract disorders, especially gastric disorders, are often experienced by people. One drug to treat this disorder has a mechanism of blocking the H2 receptor. This research was conducted to find compounds from C.verum which have the stability of bind to H2 receptors. The method used is protein modeling with swiss-model, docking with PLANTS (CHEMPLP) and activity prediction. The test results obtained that the docking score was ?- amorphene (-65,79), ?-bergamotene (-65,48), ?-copaene (-66,62), ?-cubebene (-66,46), Cadinene (-64 , 79), Camphor (-52.15), Caryophyllene (-62.61), Cinnamaldehyde (-68.17), Epicatechin (-80.43), Ergosterol (-85.24), Eugenol (-67.35), Hydrocinnamaldehyde (-65,53), Quercetin (-74,38), Protocatechuic acid (-71,49), Stigmasterol (-88,88), 4- (2,3-dihydro-3- (hydroxymethyl) - 5- (3-hydroxypropyl) -7- (methoxy) benzofuranyl] -2-methoxyphenyl (-85,29). Combined with the probability activity of compounds that have the potential to be further developed are Epicatechin and urolignoside.
POTENSI DARI EKSTRAK DAN FRAKSI KULIT BUAH MUNDAR (Garcinia forbesii) SEBAGAI TABIR SURYA BERDASARKAN NILAI SUN PROTECTION FACTOR (SPF) Muhammad Ikhwan Rizki; Samsul Hadi; Lutfi Chabib
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (201.827 KB) | DOI: 10.36387/jiis.v6i2.716

Abstract

UV rays cause skin damage such as loss of skin elasticity, wrinkles, sagging, and skin cancer. South Kalimantan is a wetland area with more than 4,000 species of medicinal plants. Mundar (Garcinia forbesii) is one of the plants in South Kalimantan. Mundar pericarp is empirically used for cosmetics which is believed to protect the skin from ultraviolet rays. The purpose of the study was to determine the sunscreen potency of the extract and fraction from pericarp of mundar (Garcinia forbesii) based on the Sun Protection Factor (SPF) parameter. The research started from material drying, making simplicia powder, extraction, and fractions. The extracts and fractions were measured for SPF values ??using a UV-Vis Spectrophotometer. The results showed that the ethanol extract and ethyl acetate fraction had weak protection, while the n-hexane fraction had extreme protective power with SPF values ??in the range of 6.51 – 30.00
MODEL RLB TURUNAN NAFTAKUINON INHIBITOR SEL LINE HELA Samsul Hadi; Uripto Trisno Santoso; Muhammad Luthfi Firdaus
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 2 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v7i2.966

Abstract

Cervical cancer is a disease that is dangerous for life. Naphtaquinone is an anticancer agent whose derivatives have been successfully synthesized, so it is necessary to study QSAR to evaluate its potency. The purpose of this study was to determine the molecular descriptors of naphtoquinone-derived compounds that have a significant effect on the anticancer activity of HeLa cells and compile them into a valid QSAR model. A total of 15 compounds from naphtoquinone derivatives were used for modeling. The descriptors that were tried included 1,863 topological descriptors and physico-chemical properties descriptors. Results of correlation analysis obtained 17 descriptors that are feasible to be tested in modeling. Results of backward method obtained 3 descriptors that have a significant effect, namely AATSC6Z, AATSC7m, and MAXaaCH. The MLR model based on 3 descriptors fulfills the goodness of fit requirements with R=0.873, R2=0.763, R 2 Adjusted=0.698, F value=0.0009 (Ftable=11.778). The results of the validation test using the CV-LOO method obtained a value of Q2=0.572 and CV-LMO obtained a value of Q2=0.518 so that this HKSA model can be stated as a valid HKSA model.
MODEL RLB TURUNAN NAFTAKUINON INHIBITOR SEL LINE HELA Samsul Hadi; Uripto Trisno Santoso; Muhammad Luthfi Firdaus
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 2 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v7i2.966

Abstract

Cervical cancer is a disease that is dangerous for life. Naphtaquinone is an anticancer agent whose derivatives have been successfully synthesized, so it is necessary to study QSAR to evaluate its potency. The purpose of this study was to determine the molecular descriptors of naphtoquinone-derived compounds that have a significant effect on the anticancer activity of HeLa cells and compile them into a valid QSAR model. A total of 15 compounds from naphtoquinone derivatives were used for modeling. The descriptors that were tried included 1,863 topological descriptors and physico-chemical properties descriptors. Results of correlation analysis obtained 17 descriptors that are feasible to be tested in modeling. Results of backward method obtained 3 descriptors that have a significant effect, namely AATSC6Z, AATSC7m, and MAXaaCH. The MLR model based on 3 descriptors fulfills the goodness of fit requirements with R=0.873, R2=0.763, R 2 Adjusted=0.698, F value=0.0009 (Ftable=11.778). The results of the validation test using the CV-LOO method obtained a value of Q2=0.572 and CV-LMO obtained a value of Q2=0.518 so that this HKSA model can be stated as a valid HKSA model.
Co-Authors Ag. Yuswanto Ag. Yuswanto Agustina, Ni Kadek Ayu Amalia Khairunnisa Amalia Khairunnisa Amalia Khairunnisa Ana Maulana Ana Muliana Arif Subekti Arif Subekti Bawaihi Bawaihi Buih, Putri Helena Junjung DENI SETIAWAN Deni Setiawan Desiya Ramayanti Azhara Desiya Ramayanti Azhara Diah Aulia Rosanti Diah Aulia Rosanti Dian Ekowati Dian Ekowati Dian Kusuma Putra Eko Suhartono Elvina Astria Agustin Endang Lukitaningsih Fadlilaturrahmah Fadlilaturrahmah, Fadlilaturrahmah Fanli Yudi Anwar Farida Istiqamah Fathul Jannah, Fathul Febriani, Noor Rahmi Fery Ramadhan Fitri Puspitasari Gunawan Gunawan Gunawan Gunawan Indriani, Erika Irawati Irawati Izma, Hayatun Khadijah, Nor Khoerul Anwar Kunti Nastiti Kunti Nastiti Kunti Nastiti Kunti Nastiti Kunti Nastiti Kunti Pelita Kuranji Blok Nastiti Liling Triyasmono Liling Triyasmono Liling tryasmono Linda Wahyuni Ludowika Adonita Tarong Lutfi Chabib, Lutfi Malahayati, Siti Melviani Melviani Mirza Maulana Ahmad Muhammad Firman Akbar Muhammad Ikhwan Rizki Muhammad Luthfi Firdaus Muhammad Syihab Setia Budi Nashrul Wathan Nastiti, Kunti Noer Komari Normaidah, Normaidah Normilawati Noval Noval Noval Noval Nugi Maulana Nur Mahdi Nurul Mardiati Nurul Mardiati Okta Muthia Sari Pertiwi Awilda Rafiah Anggianingrum Rahmadina, Nazwa Rahmawati, Nanda Hesti Ramadani, Rizka aulia Ratnapuri, Prima Happy Rezka Fajar Ramadhan Rinda, Ririn Purnama Riswandayani Savitri Risye Hendry Rizki Swastika Puri ROBIATUL ADAWIYAH RR. Endang Lukitaningsih Salma Salma Sefa Nur Khalifah Setia Budi Sheila Nurrahmah Shindi, Muhammad Riki Sintya Oktaviani Sri Oktaviana Sari Sri Oktaviana Sari Subagus Wahyuono Subagus Wahyuono Suci Kamelia Sukmana, M. Laily Qadry Tazkia Safarina Ulfah, Nahdiati Umi Nur Hapifah Umi Nur Hapifah Uripto Trisno Santoso Viogenta, Pratika Wijaya, Eka Setya Yusri Yusri Yusri Yusri