Article Per Year (5 Year)
p-Index From 2021 - 2026
3.11
P-Index
This Author published in this journals
All Journal Jurnal Ilmiah Farmasi EKSAKTA: Journal of Sciences and Data Analysis Indonesian Journal of Pharmaceutical Science and Technology Majalah Obat Tradisional INDONESIAN JOURNAL OF PHARMACY QUANTUM: Jurnal Inovasi Pendidikan Sains Pharmascience Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Media Bahasa, Sastra, dan Budaya Wahana JFIOnline Jurnal Ilmu Kefarmasian Indonesia Jurnal Surya Enthusiastic : International Journal of Applied Statistics and Data Science Journal of Applied Nursing and Health Khazanah: Jurnal Mahasiswa Jurnal Riset Kebidanan Indonesia JKKI : Jurnal Kedokteran dan Kesehatan Indonesia SPIKESNAS Media Farmasi Borneo Journal of Pharmacy Jurnal Keperawatan Mandira Cendikia (JKMC)
Hayati, Farida
Prodi Farmasi, Fakultas MIPA, Universitas Islam Indonesia, Yogyakarta Prodi Profesi Apoteker, Fakultas MIPA, Universitas Islam Indonesia, Yogyakarta
Religion Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

Published : 40 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : INDONESIAN JOURNAL OF PHARMACY

 1 
The effect of extract Kaempferia galanga rhizomes on the elimination kinetics of quinidine in rabbits Hayati, Farida; Hakim, Lukman
Indonesian Journal of Pharmacy Vol 14 No 4, 2003
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (234.269 KB) | DOI: 10.14499/indonesianjpharm0iss0pp177-181

Abstract

The research was aimed to observe the effect of the juice of Kaempferia galanga rhizomes on quinidine elimination kinetics in rabbits. The study on interaction of extract Kaempferia galanga rhizomes to quinidine elimination kinetic was conductedly employing a cross randomized design using male rabbits which were divided into 3 groups (6 rabbits for each group). The groups were given a single oral quinidine 30 mg/kg BW as a control group and were conferred single oral extract “kencur” 4.8 mi/kg BW each dose for 4 days prior to the treatment with quinidine. Serial blood samples(0,2 ml) were withdrawn at various interval time via the ear marginal for spectrofluorometric analysis of unchanged quinidine in blood. The concentration of quinidine was determined using a standard curve and the concentration to time data was used to determine quinidine elimination kinetics i.e. Clt and MRT. The results indicated that extract “Kencur” was found to decrease quinidine clearance 17,19% and 7,07% (P>0,05) and increase quinidine MRT198,89% and 71,70% (p>0,05).Key words : Kaempferia galanga rhizomes, quinidine, elimination
Isolation and identification of eurycomanone from akar pasak bumi (Eurycoma longifolia, Jack) and its antiangiogenic activity Sugiyanto .; Nina Salamah; Mae Sri Hartati; Farida Hayati; Pinus Jumariyatno
Indonesian Journal of Pharmacy Vol 20 No 3, 2009
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (371.242 KB) | DOI: 10.14499/indonesianjpharm0iss0pp118-126

Abstract

Pasak bumi is one of the Indonesian original plants having anti cancer activity. One compound of akar pasak bumi, i.e eurycomanone was proven to have cytotoxic effect on cancer cell culture by apoptosis induction on HeLa cells. Therefore, this study was aimed to isolate and identify euycomanone from akar pasak bumi and to look at the anti angiogenic activity of the compounds on corio alantois membrane (CAM) of chicken embryo induced by bFGF.The akar pasak bumi was ground and was macerated with methanol. The macerate was fractioned by mean of VLC. Six fractions was obtained. The second fraction exhibited two spots on a TLC system, one spot was cochromatographed with eurycomanone as the reference standart and another spot exhibited blue fluorecence at 254 nm. This second fraction, then, was chromatographed on a preparative scale TLC to separate isolate A. Anti angiogenic test was performed for Isolate A at concentration series of 5, 10, 15, 20, 40 μg/mL respectively. Egg embrio (8-9 days) were divided into 8 groups. The first group was implanted paper disc only, the second group were given bFGF on Tris HCl buffer and the third group were given bFGF (on Tris HCl buffer) + 0,8 % DMSO. The fourth to eighth group were induced by 10 ng bFGF and the test preparation at the respective concentration. After incubation at 39 °C for 3 days, each egg was opened, the content of each was aspired and discarded, the CAM sticked to its shell was examined macroscopically and microscopically for the formation of new blood vessels.Based on spectral data of UV, IR, 1H NMR, 13C NMR and MS of isolate A and comparison with the spectral data of the standart, the isolate A was eurycomanone. Eurycomanone inhibited angiogenesis at concentration of 10 μg/mL.Key words: antiangiogenic, angiogenesis, E.longifolia, eurycomanone,CAM.
Co-Authors . PRAPTIWI Agung Giri Samudra Amalinda Setya Kartika Arba Pramundita Ramadani Arde Toga Nugraha Ari Wibowo Arief Rahman Hakim Ariefaldy, Muhammad Ilhan Awaluddin, Rizki Cynthia Astiti Putri DAYAR ARBAIN Desyandri Desyandri Dhina Widayati Dhina Widayati, Dhina DIAN AMALIA Dian Sukma Dimas Adhi Pradana Dimas Adhi Pradhana Dina Zakiyyatul Fuadah, Dina Zakiyyatul Diny Lidya Djoko Wahyono Djoko Wahyono Djoko Wahyono Dwi Brilyani Sandy Dwi Setyorini Elok Atiqoh Fajarotin, Dwi Rori Febrianti, Shabrina Adzhani Fitriani, Hannie Gina Nadia Hastarin Ginna Zabrina Girianto, Pria Wahyu Romadhon Hakim, Lukman Hasanah, Primadian Helmina Wati Herianto Pandapotan, Herianto Indriani Indriani Islamiyah Neda Rahayu Khaerunnisa, Siti Laviana Nita Ludyanti Leny Leny, Leny Lian Widi Astutik Ludyanti, Laviana Lutfi Chabib, Lutfi M.Pd S.T. S.Pd. I Gde Wawan Sudatha . Mae Sri Hartati Wahyuningsih Maulaya, Ikvini Muh Iqbal Pangestu Muhammad Agus Firmansyah Ramadhani Muhammad Iqbal Pangestu Muhammad Sulaiman Zubair Mustaqim, Rafli Mulkan Mustarianti, Lila Nina Salamah Nurlaily, Diana Parham Saadi, Parham Pinus Jumariyatno Pinus Jumaryatno Poluan, Jesica Carine Puspita, Arum Dwi Putri Widi Renditya Ismiyati Retno Murwanti Rilia Iriani Riptasari, Rhatna Dewi Rizki Awaluddin Rizsanti Meirina Satar Sandi, Dita Ayulia Dwi Sandi, Dita Ayulia Dwi Satrio, Rezky Metra Septian Pradana, Dimas Sitarina Widyarini Stiani, Sofi Nurmay Sugiyanto . Sugiyanto Sugiyanto Syahmani Syahmani Taukhid, Muhammad Tri Alfiana, Yolanda Velincia Tanriono, Levana Wahyu Utaminingrum Yandi Syukri Yogo Dwi Prasetyo Yundari, Yundari Yusmein Uyun