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All Journal Jurnal Pendidikan dan Pembelajaran Kimia (JPPK) Jurnal Penelitian dan Pembelajaran IPA Journal of Natural Sciences and Mathematics Research JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Pendidikan Kimia (JPKim) Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Pengabdian Kepada Masyarakat (Mediteg) JURNAL PENELITIAN PERAWAT PROFESIONAL Yumary: Jurnal Pengabdian kepada Masyarakat Mitra Mahajana: Jurnal Pengabdian Masyarakat International Journal of STEM Education for Sustainability Jurnal Kolaboratif Sains Jurnal Pijar MIPA Jurnal Ilmiah Berkala: Sains dan Terapan Kimia Jurnal Ilmu Kesehatan dan Farmasi Jurnal Medical Laboratory Jurnal Ilmiah Pengabdian dan Inovasi PCJN Pharmaceutical and Clinical Journal of Nusantara BIOCITY: Journal of Pharmacy Bioscience and Clinical Community
Muhammad Eka Putra Ramandha
Farmasi, Fakultas Kesehatan, Universitas Bumigora, Jl. Ismail Marzuki No.22, Cilinaya, Kec. Cakranegara, Kota Mataram, Nusa Tenggara Barat. 83127
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Aktivitas Antioksidan Ekstrak Metanol dan Fraksi N-Heksan-Etil Asetat Buah Paprika Merah (Capsicum annuum L.) Anisah, Nur; Warsi, Warsi; Ramandha, Muhammad Eka Putra; Isasih, Widani Darma; Inayati, Rizqa; Indriani, Nurul
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol. 1 No. 1 (2022): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v1i1.2459

Abstract

Buah paprika merah (Capsicum annuum L.) mengandung diantaranya adalah vitamin E, vitamin C, karotenoid, dan kapsaisinoid yang dapat digunakan sebagai antioksidan. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan pada ekstrak metanol dan fraksi n-heksan-etil asetat buah paprika merah. Buah paprika merah segar diekstraksi dengan metode maserasi menggunakan pelarut metanol teknis kemudian difraksinasi secara bertingkat menggunakan pelarut n-heksan-dietil eter, hasil fraksi tidak larut n-heksan-dietil eter kemudian difraksinasi kembali menggunakan pelarut n-heksan-etil asetat. Fraksi n-heksan-etil asetat diuji secara kualitatif terhadap senyawa karotenoid yaitu β-karoten dengan uji KLT menggunakan fase diam silika gel F254 dan fase gerak metanol: aseton (1:1). Uji kuantitatif aktivitas antioksidan dilakukan dengan metode penangkapan radikal DPPH dengan parameter nilai IC50. Nilai IC50 selanjutnya dianalisis dengan menggunakan SPSS versi 20. Hasil uji kualitatif menunjukkan bahwa ekstrak metanol dan fraksi n-heksan-etil asetat mengandung senyawa β-karoten. Aktivitas antioksidan ekstrak metanol, fraksi n-heksan-etil asetat, dan standar β-karoten memiliki nilai IC50 berturut-turut sebesar 307,91, 281,69, dan 81,26 μg/mL. Berdasarkan hasil statistik, nilai IC50 fraksi n-heksan-etil asetat lebih kecil signifikan apabila dibandingkan dengan ekstrak metanol buah paprika merah. Namun lebih besar apabila dibandingkan dengan standar β-karoten. Fraksi n-heksan-etil asetat memiliki aktivitas antioksidan yang lebih poten apabila dibandingkan dengan ekstrak metanol buah paprika merah. Namun kurang poten apabila dibandingkan dengan standar β-karoten.
Uji Aktivitas Antibakteri Ekstrak Etanol Daun Bugenvil (Bougainvillea glabra) pada Bakteri Staphylococcus aureus Legistari, Mirna; Ramandha, Muhammad Eka Putra; Pratiwi, Baiq Yulia Hasni
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 3 No 1 (2024): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v3i1.4473

Abstract

Bougainvillea leaves contain various secondary metabolite compounds, such as flavonoids, tannins, and saponins. These compounds have the potential to be antibacterial to treat infectious diseases caused by the pathogenic bacteria Staphylococcus aureus. This study aims to determine the antibacterial activity of bougainvillea leaf ethanol extract against the growth of S. aureus bacteria. This study carried out antibacterial activity tests using the agar well-diffusion method. Data analysis used the One-way ANOVA statistical test, with the Shapiro-Wilk normality test and the Levene homogeneity test. The results of phytochemical tests showed that the ethanol extract of bougainvillea leaves contains flavonoids, tannins, and saponins. In antibacterial tests with concentrations of 25%, 50%, 75%, and 100%, the diameter of the inhibition zone obtained ranged from 20-27.3 cm. This inhibition zone is included in the strong to very strong category. In addition, statistical tests showed that each concentration of bougainvillea leaf ethanol extract affected the growth of S. aureus bacteria compared to negative controls. Based on the description above, bougainvillea leaf ethanol extract has the potential to inhibit the growth of S. aureus.
Uji Aktivitas Antibakteri Ekstrak Etanol Bunga Gemitir (Tagetes erecta Linn.) terhadap Bakteri Staphylococcus aureus dan Escherichia coli Marsah, Unggu Putri Six; Ramandha, Muhammad Eka Putra; Pratiwi, Baiq Yulia Hasni
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 3 No 1 (2024): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v3i1.4474

Abstract

Gemitir flowers (Tagetes erecta Linn.) contain secondary metabolite compounds such as flavonoids, phenolics, saponins and carotenoids which have the potential as antibacterials that can be used in treating infections caused by pathogenic bacteria Staphylococcus aureus and Escherichia coli. The purpose of this study was to determine the effective concentration of etanol extract of gemitir flowers and the comparison of antibiotic inhibition with etanol extract of gemitir flowers in inhibiting the growth of S. aureus and E. coli bacteria. This study is an experimental study and was analyzed using the One Way ANOVA statistical test. The results showed that gemitir flower extract positively contained secondary metabolites in the form of flavonoids, phenolics and saponins. The antibacterial activity test of etanol extract of gemitir flowers can inhibit S. aureus and E. coli at concentrations of 85%, 90%, 95% and 100% with the diameter of the inhibition zone obtained of 17-31.6 mm which is included in the strong-very strong category. Based on the description above, it can be concluded that the etanol extract of gemitir flowers has the potential to inhibit the growth of S. aureus and E. coli bacteria.
Antiinflammatory Activity of Bangle Rhizome (Zingiber purpureum Roxb) Ethanol Extract on Rat Carrageenan Induced and Erythema Method Mia Ariasti; Muhammad Eka Putra Ramandha; Sri Winarni Sofya
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 12 No. 1 (2025): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v12i12025.50-58

Abstract

Background: Inflammation is a physiological response triggered by cellular damage, typically characterized by symptoms such as edema. Objective: This study was conducted to evaluate the anti-inflammatory activity of the ethanol extract of Bangle rhizome (Zingiber purpureum Roxb.) using the carrageenan-induced paw edema method and the UVB-induced erythema method. The most effective dose demonstrating significant anti-inflammatory activity was also determined. Methods: The bangle rhizome (Zingiber purpureum Roxb) was subjected to maceration using 96% ethanol. A total of 25 rats were randomly divided into five groups: negative control (0.5% CMC-Na), positive control (diclofenac sodium at 0.9 mg/200 g body weight), and treatment groups receiving ethanol extract of bangle rhizome at doses of 5, 10, and 20 mg/200 g body weight. In the carrageenan-induced method, the edema volume in the rat paw was measured following the administration of 0.8% lambda-carrageenan. In the erythema method, the degree of inflammation was assessed using UVB-induced erythema scoring. Results and Conclusion: Anti-inflammatory activity was observed at doses of 5, 10, and 20 mg/200 g body weight in the carrageenan model and at doses of 10 and 20 mg/200 g in the erythema model. The most potent anti-inflammatory effect was recorded at the dose of 20 mg/200 g body weight, which was comparable to the positive control in both models. The presence of flavonoids and steroids in the extract may contribute to the observed anti-inflammatory activity.
Pelatihan Digital Marketing dan Formulasi Sabun dari Minyak Kelapa di Sentra Industri Pengolahan Kelapa Lombok Utara Yuliana, Ika; Ramandha, Muhammad Eka Putra; Pratiwi, Baiq Yulia Hasni
Yumary: Jurnal Pengabdian kepada Masyarakat Vol. 6 No. 1 (2025): September
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/yumary.v6i1.3800

Abstract

Purpose: This service aims to increase Sentra Industri Pengolahan Kelapa knowledge and skill about soap formulation from coconut oil, thus they could produce a good quality coconut oil soap. Also, this act aims to educate them how to sell their product via social media such as Instagram, Tiktok, etc. Research methodology: This service was conducted at Sentra Industri Pengolahan Kelapa, Kab. Lombok Utara, NTB and attended by 30 participants. It was consist of two main event: (1) Education and training of coconut oil soap formulation and (2) Education and training of social media used for digital marketing. The understanding of audience was measured using pre-test and post-test questionnaire. The data was analyzed using SPSS 27. Results: According to questionnaire collected, there are significant increase of audience knowledge regarding soap formulation and the use of social media for digital marketing after training. Conclusions: In short, the service has a significant impact on Sentra Industri Pengolahan Kelapa’s knowledge and skill in formulating a good quality coconut oil soap. Moreover, Sentra Industri Pengolahan Kelapa could start sell their product via social media created. Limitations: Large-scale production and marketing of the soap product are required to be able to measure the profit increase of Sentra Industri Pengolahan Kelapa. Contribution: This training would benefit the small and medium enterprises (SMEs) to make a standarized coconut oil soap and take advantage of social media to sell their product. Therefore, this would increase omzet of Sentra Industri Pengolahan Kelapa and eventually improving the economy of Kab. Lombok Utara.
Pemanfaatan Eklstrak Limbah Kulit Buah Rambutan (Nephelium Lapaceum L). dalam Formulasli Body Lotion Paturrahmi, Wilda Marta; Indrianii, Nurul; Ramandha, Muhammad Eka Putra
Jurnal Penelitian Perawat Profesional Vol 6 No 5 (2024): Oktober 2024, Jurnal Penelitian Perawat Profesional
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jppp.v6i5.4469

Abstract

Penelitian ini bertujuan untuk mengetahui efek antioksidan ekstrak kulit buah rambutan (Nephelium lappaceum L.) dalam melembabkan kulit dan menentukan formulasi body lotion yang paling efektif. Kulit buah rambutan mengandung senyawa antioksidan yang berpotensi memberikan manfaat bagi kesehatan kulit.Penelitian eksperimental ini menguji aktivitas antioksidan ekstrak kulit buah rambutan dengan variasi konsentrasi menggunakan metode DPPH. Aktivitas antioksidan diukur dengan spektrofotometer UV-Vis. Ekstrak kemudian diformulasikan ke dalam beberapa variasi body lotion yang dievaluasi profilnya meliputi organoleptis, homogenitas, pH, daya sebar, daya lekat, viskositas, dan iritasi. Hasil penelitian menunjukkan bahwa ekstrak kulit buah rambutan memiliki aktivitas antioksidan yang berpotensi melembabkan kulit. Beberapa formulasi body lotion dengan penambahan ekstrak memenuhi kriteria sediaan yang baik. Ekstrak kulit buah rambutan berpotensi sebagai bahan aktif dalam formulasi body lotion dengan efek melembabkan. Penelitian lebih lanjut diperlukan untuk mengoptimalkan formulasi dan menguji efektivitasnya pada manusia.
ANTIHIPERGLIKEMIA REBUSAN AIR DAUN SALAM (Syzygium polyanthum) TERHADAP PROFIL PEKERJA DI DESA PAOK MOTONG, KECAMATAN MASBAGIK, LOMBOK TIMUR Kresnapati, I Nyoman Bagus Aji; Ramandha, Muhammad Eka Putra; Sofya, Sri Winarni
Jurnal Ilmu Kedokteran dan Kesehatan Vol 11, No 1 (2024): Volume 11 Nomor 1
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v11i1.12963

Abstract

Abstrak: Antihiperglikemia Rebusan Air Daun Salam (Syzygium Polyanthum) Terhadap Profil Pekerja Di Desa Paok Motong, Kecamatan Masbagik, Lombok Timur. Diabetes Mellitus (DM) merupakan penyakit kronis yang ditandai peningkatan kadar gula darah secara terus menerus akibat pankreas secara tidak efektif mensekresi hormon insulin. Daun salam (Syzygium Polyanthum) berperan sebagai obat pada berbagai penyakit seperti lambung, wasir, anti diare, diabetes mellitus, anti hiperkolesterol serta anti hipertensi. Tujuan penelitian ini untuk mengetahui antihiperglikemia rebusan air daun salam (Syzygium Polyanthum) berdasarkan profil pekerja. Sebanyak 41 responden di Desa Paok Motong Barat, Lombok Timur di ukur kadar Gula Darah Sewaktu (GDS) sebelum (pre-test) dan sesudah (post-test) pemberian air rebusan daun salam. Analisis Statisktik Paired Test digunakan untuk mengetahui perbedaan kadar glukosa darah pre-test dan post-test pemberian air rebusan daun salam. Hasil penelitian menunjukkan terjadi penurunan kadar gula darah secara signifikan (p= 0,001) setelah pemberian rebusan daun salam. Berdasarkan karakteristik pekerjaan, rerata penurunan kadar gula tertinggi yaitu berprofesi ibu rumah tangga (IRT) sebesar 20,42 mg/dL, pegawai 18 mg/dL, pedagang 16,67 mg/dL dan terendah petani sebesar 13,79 mg/dL. Terdapat efektivitas secara signifikan (p=0,001) pemberian rebusan daun salam terhadap penurunan kadar glukosa darah dan semua profesi yang ada di Desa Paok Motong. 
Edukasi Pemanfaatan Bahan Alam sebagai Asi Booster pada Ibu Hamil dan Menyusui Novitarini; Muhammad Eka Putra Ramandha; Baiq Yulia Hasni Pratiwi; Lalu Busyairi Muhsin; Mia Ariasti; Sri Winarni Sofya
Jurnal Ilmiah Pengabdian dan Inovasi Vol. 2 No. 4 (2024): Jurnal Ilmiah Pengabdian dan Inovasi (Juni)
Publisher : Insan Kreasi Media

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57248/jilpi.v2i4.399

Abstract

Low levels of exclusive breastfeeding will increase the risk of stunting and susceptibility to disease in the future. One of the reasons for this low supply is that breast milk production is not smooth, so it is necessary to facilitate the production of breast milk from natural ingredients. This service aims to educate about using natural ingredients to enable breast milk for pregnant and breastfeeding mothers. This service method has 4 stages: namely approach, preparation, delivery of material, and discussion. The results of the service showed that the village community understood the natural ingredients that could be used to facilitate breast milk, namely katuk leaves, turi, spinach and banana blossoms. Apart from that, in the service, proper processing is demonstrated so that the content is not lost or reduced. The conclusion of this service is that the community of Preparation Reban Madani village will utilize natural ingredients with proper processing to facilitate breast milk so that they can carry out exclusive breastfeeding. The implication of community service is that village knows how to process local plants to facilitate breast milk.
Introducing Children of Environmental Issue in Sekotong Timur Through Project Based Learning Dewi, Puspita; Yuliatin, Riyana Rizki; Hadi, Sirojul; Syarifaturrahman, Wahyu Kamil; Latif, Kurniadin Abd; Sujaka, Tomi Tri; Ramandha, Muhammad Eka Putra; Fatimatuzzahra, Fatimatuzzahra
Mitra Mahajana: Jurnal Pengabdian Masyarakat Vol. 3 No. 2 (2022): Volume 3 Nomor 2 Tahun 2022
Publisher : LPPM Universitas Flores

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37478/mahajana.v3i2.1834

Abstract

Nowadays, the environmental issue is one of the biggest problems worldwide. It is because the climate change deteriorates from time to time; the earth becomes warmer, and pollution polluted the environment. Humans have a pivotal role in changing the earth because they damage the ecosystem by using numerous plastics, throw many of rubbish, and cutting plenty of trees. As a result, climate change and global warming become worse. Consequently, all stakeholders need to take the responsibility to protect the earth. Some groups blame the government; however; environmental issues are the government’s responsibility and all society’s matters, including academicians. This community service activity was conducted in one of the remote areas in Bunbeleng village, East Sekotong district, East Lombok. The Project was held by Relawan Saling Jaga Indonesia (Relasi) funded by Direct Aid Program (DAP) Australian Consulate-General, Bali Indonesia coordinated by Isyatul Mardiah. This project was conducted based on Project-based Learning (PBL). There are five stages in implementing this project: planning the project, monitoring the project, presenting the project, and evaluating the project. The environment topics were elaborated in this community through the PBL. After the program, the students have more knowledge in reducing, recycling, and reusing plastics and green programs with planting trees. The students were very enthusiastic and motivated. The collection of the project was exhibited isn the classroom.
Aktivitas Antibakteri Ekstrak Daun Kelor (Moringa oleifera Lam.) terhadap Staphylococcus epidermidis Penyebab Jerawat: Antibacterial Activites Cream Extracts of Kelor Leaves (Moringa oleifera Lam.) against Staphyloccus Epidermidis Cause of Acne Novitarini; Muhammad Eka Putra Ramandha; Baiq Yulia Hasni Pratiwi
Jurnal Kolaboratif Sains Vol. 7 No. 5: MEI 2024
Publisher : Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jks.v7i5.5075

Abstract

Prevalensi jerawat dalam masa remaja dan resistensi antibiotik yang tinggi mendorong eksplorasi alternatif antibiotik berbasis herbal. Daun kelor (Moringa oleifera Lam.) merupakan tanaman yang memiliki aktivitas antibakteri karena mengandung senyawa flavonoid, alkaloid, tanin, dan saponin yang dapat dijadikan sebagai antibiotik berbasis herbal. Penelitian ini bertujuan untuk menguji aktivitas antibakteri dari ekstrak daun kelor (5, 10, dan 15%) terhadap Staphylococcus epidermidis penyebab jerawat. Pengujian ini menggunakan metode difusi sumuran untuk melihat aktivitas antibakteri (zona hambat) dari ekstrak daun kelor berbagai konsentrasi terhadap Staphylococcus epidermidis. Data dianalisis menggunakan One Way ANOVA dengan program SPSS. Hasil yang diperoleh berupa diameter zona hambat ekstrak etanol daun kelor konsentrasi 5, 10, 15% yaitu: 23,01 mm, 23,34 mm dan 23,68 mm. Pengujian ini mempunyai nilai Sig = 0,000 yang berarti rata rata antar kelompok terdapat perbedaan yang signifikan. Dapat disimpulkan bahwa zona hambat ekstrak daun kelor tergolong mempunyai daya hambat kuat terhadap Staphylococcus epidermidis.
Co-Authors A Wahab Jufri Alasa, Victor M. Aliefman Hakim Aliefman Hakim Aliefman Hakim Anisah, Nur Astrid Ekaningsih Baiq Yulia Hasni Pratiwi Eka Nurul Qomaliyah Ekaningsih, Astrid Fatimatuzzahra Fatimatuzzahra Hakim, Aliefman Inayati, Rizqa Indah Juwita Sari Irman Idrus Jamaluddin Jamaluddin Jamaluddin Jamaluddin Jamaluddin, Jamaluddin Jufri, A. Wahab Jufri, Abdul Wahab Kresnapati, I Nyoman Bagus Aji Kurniadin Abd Latif Legistari, Mirna Marsah, Unggu Putri Six Mia Ariasti Mia Ariasti Muchsin, Lalu Busyairi Mudawil Qulub Muhsin, Lalu Busyairi Nasrun, Efa Kelya Novitarini Nur Anisah Nurul Indriani Nyoman Bagus Aji K Paturrahmi, Wilda Marta Puspita Dewi, Puspita Ramadhani, Muhammad Wisda Pradja Riyana Rizki Yuliatin Rizqa Inayati Sirojul Hadi Sofya, Sri Winarni Sri Winarni Sofya Sri Winarni Sofya Sujaka, Tomi Tri Syarifa Wahidah Al Idrus Wahyu Kamil Syarifaturrahman, Wahyu Kamil Warsi Warsi Warsi Warsi Widani Darma Isasih Yulia Hasni Pratiwi Yuliana, Ika