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All Journal METAMORFOSA Journal of Biological Sciences Jurnal Biosains Pascasarjana Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Journal of Social Research KREATIF: Jurnal Pengabdian Masyarakat Nusantara SWARNA Jurnal Pelayanan dan Pengabdian Masyarakat Indonesia Jurnal Pengabdian Kepada Masyarakat Medical Laboratory Journal Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran Quantum Wellness : Jurnal Ilmu Kesehatan Vitamin: Jurnal Ilmu Kesehatan Umum SWARNA: Jurnal Pengabdian Kepada Masyarakat Jurnal Pelayanan Masyarakat
Ni Ketut Yuliana Sari
Poltekes Kemenkes Kupang
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Aktivitas Antibakteri Fungi Endofit dari Rimpang Jahe Gajah (Zingiber officinale var. Roscoe) terhadap Methicillin Resistant Staphylococcus aureus (MRSA) Ni Ketut Yuliana Sari; Retno Kawuri; Ni Made Susun Parwanayoni
Metamorfosa: Journal of Biological Sciences Vol 7 No 2 (2020)
Publisher : Prodi Magister Ilmu Biologi, Fakultas MIPA, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/metamorfosa.2020.v07.i02.p11

Abstract

This study aimed to isolate and test the antibacterial activity of endophytic fungi from elephant ginger rhizome (Zingiber officinale var. Roscoe) against MRSA. This research is an exploratory research which is continued with experimental. The research sample was obtained from three locations. The first sample was from Pancasari Village, Singaraja, Bali. The second sample was from Peguyanganan Village, Denpasar, Bali. The third sample is from Tebuana Village, Tampaksiring, Bali. This research was conducted at the Microbiology Laboratory, Department of Biology, Faculty of Mathematics and Natural Sciences, Udayana University. Eight isolates of endophytic fungi were successfully isolated with each inhibitory zone against MRSA, Fusarium sp. 1 (21 mm), Fusarium sp. 2 (19 mm), Fusarium sp. 3 (20 mm), Fusarium sp. 4 (21 mm), Aspergillus sp. 1 (32 mm), Aspergillus sp. 2 (25 mm), Fungi S3F1 (13 mm) and Fusarium sp. 5 (25 mm). This shows that endophytic fungi can be used as an alternative producer of antibacterial compounds. Keywords: Antibacterial, Endophytic fungi, Methicillin Resistant Staphylococcus aureus.
Screening Kadar C-Reaktiv Protein Pada Penderita TB Dengan Terapi Obat Anti Tuberculosis Di Kabupaten Kupang Adrianus Ola Wuan; Ni Ketut Yuliana Sari; Yuanita Rogaleli; Wilhelmus Olin
KREATIF: Jurnal Pengabdian Masyarakat Nusantara Vol. 2 No. 3 (2022): September : Jurnal Pengabdian Masyarakat Nusantara
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/kreatif.v2i3.589

Abstract

tuberculosis, yang menyerang berbagai organ terutama paru-paru. Mtb mengandung berbagai C-polisakarida yang dalam tubuh bisa diketahui dengan pemeriksaan CRP. CRP adalah suatu protein alphaglobulin yang timbul dalam darah bila terjadi inflamasi. Tujuan pemeriksaan untuk mengetahui gambaran C-Reaktif Protein pada pasien Tuberkulosis dengan terapi Obat Anti Tuberkulosis (OAT) di Puskesmas Naibonat. Metode yang digunakan bersifat deskriptif pendekatan cross sectional. Populasi dari penelitian ini adalah seluruh pasien Tuberkulosis yang tengah menjalani terapi OAT di Puskesmas Naibonat berjumlah 20 orang. Hasil penelitian menunjukkan CRP positif sebanyak 7 orang (35%) dan CRP negatif sebanyak 13 orang (65%) paling banyak ditemukan pada perempuan, umur 26-50 tahun dan > 50 tahun, dan kategori pendidikan menengah atas (SMA).Kesimpulan dari 20 orang pasien Tuberkulosis yang tengah menjalani terapi OAT, yang mempunyai CRP positif sebanyak 7 orang (35%) dan CRP negatif sebanyak 13 orang (65%). Kata Kunci: Kadar CRP, Penderita TB, Terapi OAT.
EFFECT OF BLACK GRAPE EXTRACT ON CD4+ and CD8+ EXPRESSION IN MICE INFECTED WITH Salmonella typhimurium rian anggia destiawan; septyana eka rahmawati; anas fadli wijaya; Ahdiah Imroatul Muflihah; Mutia Hariani Nurjanah; Sholihatil hidayati; Ni Ketut Yuliana sari
Jurnal Biosains Pascasarjana Vol. 24 No. 1SP (2022): JURNAL BIOSAINS PASCASARJANA: SPECIAL ISSUE
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v24i1SP.2022.54-63

Abstract

Salmonelosis is a disease caused by the Salmonella sp. that causes a decrease in CD4+ expression. Black grape can boost the immune system through CD4+/CD8+ proliferation. The purpose of this study was to evaluate the activity of black grape extract to CD4+ and CD8+ expression in mice infected with Salmonella typhimurium. Research method is extract of black grapes, Salmonella typhimurium 108 infection, bacterial evaluation, extract therapy, flowcytometery examination, and 95% Anova test. The results of Anova test showed that the expression of CD4+ and CD8+ is not different. Biologically, an increase in CD4+ and CD8+ expression at doses of 100 mg/KgBB. A decrease in CD4+ and CD8+ expression at doses of 200 mg/KgBB and 400 mg/KgBB. Conclusion, biologically, black grape extract can increase the expression of CD4+ and CD8+ at low doses, as well as may decrease the expression of CD4+ and CD8+ at moderate to high doses.
The Number of CD4+ T Cells on HIV/AIDS Patients who Have Received ARV Therapy Adrianus Olawuan; Ni Ketut Yuliana Sari; Novian Agni Yudaswara; Neny Foekh; Arista Day Atajama
Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Vol 12 No 4 (2022): Jurnal Ilmiah Permas: jurnal Ilmiah STIKES Kendal: Oktober 2022
Publisher : Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (266.518 KB)

Abstract

Human immunodeficiency virus (HIV) is an infection that attacks the body’s immune system, specifically the white blood cells called Lymphocytes CD4+ T cells. Antiretroviral therapy is the main treatment used in the management of HIV / AIDS. Antiretroviral therapy proved able to suppress viral replication and increase the number of CD4 T-cells so as to suppress the progression of the disease. CD4+ T cell counts is an important indicator to determining the level of immunity of the human body, maintaining the number of CD4+ T cells in normal limits to defend themselves from complications related to HIV/AIDS in particular to prevent opportunistic infections. The number of CD4+ T cells will determine when people living with HIV should begin antiretroviral therapy. To determine the immune status and disease progression in a person infected with HIV, a CD4+ T cell count is performed. Without antiretroviral (ARV) therapy, most people living with HIV/AIDS (PLWHA) will become progressively immunodeficient, which is characterized by a decrease in the number of CD4+ T cells, then progresses to AIDS and can end in death. The purpose of this study was to describe the number of CD4+ T cells in HIV/AIDS patients who had received ARV therapy at Prof. Hospital. Dr. W.Z. Johannes Kupang. Descriptive observational analysed data from medical record of HIV/AIDS patients with antiretroviral therapy. A Total 100 patients who were eligible included in the study had both a CD4 lymphocyte CD4+ T cell count during 2020-2021. The average difference before and after therapy using Test with p-value 0.000 (p-value <0.05) indicates that there is a significant difference between the number of Lymphocytes CD4+ T cells counts before and after therapy.
Validity of Examination of Complex Specific Antigen Mycobacterium Tuberculosis Rapid Immunochromatography Method in Patients with Pulmonary Tuberculosis Adrianus Ola Wuan; Marni Tangkelangi; Ni Ketut Yuliana Sari
Journal of Social Research Vol. 2 No. 4 (2023): Journal of Social Research
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/josr.v2i4.793

Abstract

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis which can be transmitted from one person to another by inhaling droplets coughed or sneezed by an infected person. One of the most recent technologies today is the rapid immunochromatography (ICT) method for testing TB antigens. This test detects antigens secreted by Mycobacterium tuberculosis, namely the early secretory antigenic target 6 kDa protein (ESAT6), culture filtrate protein (CFP 10), and Mycobacterium tuberculosis protein (MPT64) encoded by region of difference genes (RDI, RD2, and RD3). The purpose of this study was to determine the validity of TB ICT antigens in diagnosing pulmonary tuberculosis. The research method used is a diagnostic test with a cross-sectional study design. The population of this study was all pulmonary TB patients who were examined at the Prof. Hospital Laboratory. W.Z. John. The samples used in this study amounted to 81 samples which were preceded by smear examination and then 47 samples of M. tuberculosis culture on Lowenstein Jensen media which was used as the gold standard, the results of the examination were 41 samples growing and 6 samples not growing. The sensitivity and specificity of the Rapid ICT TB antigen test were 75.61% and 100%, respectively. The conclusion of the rapid ICT TB antigen test has high validity, so it can be used as an alternative laboratory test for the diagnosis of pulmonary TB.
SCREENING KADAR C-REAKTIV PROTEIN PENDERITA HIPERTENSI PADA MASYARAKAT DESA BONE KECAMATAN NEKAMESE KABUPATEN KUPANG Adrianus Ola Wuan; Ni Ketut Yuliana Sari; Wilhelmus Olin; Michael Bhadi Bia
SWARNA: Jurnal Pengabdian Kepada Masyarakat Vol. 2 No. 12 (2023): SWARNA: Jurnal Pengabdian Kepada Masyarakat, Desember 2023
Publisher : LPPM Sekolah Tinggi Ilmu Ekonomi 45 Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/swarna.v2i12.1068

Abstract

Hipertensi adalah meningkatnya tekanan darah atau kekuatan menekan darah pada dinding rongga dimana darah itu berada. Hipertensi akan membuat kerja jantung lebih berat, bila hipertensi berlangsung lama maka akan menyebabkan kerusakan yang terjadi pada jantung (melalui arteri koroner) dan menyebabkan aterosklerosis. Hipertensi akan mengakibatkan hilangnya elastisitas arteri, meningkatnya aktivitas dan tegangan akhirnya akan melemahkan dinding arteri dan melukai permukaanya. Luka dan peradangan kecil mulai terbentuk, kemudian akan menarik kolesterol berbahaya dalam jumlah besar, serta bahan-bahan lain yang bersifat mengiritasi, lalu seiring berjalannya waktu akan semakin menumpuk sehingga menyebabkan arteri menjadi tidak elastis lagi. Setelah dibiarkan bertahun-tahun maka tekanan darah tinggi yang terus menerus ini akan menyebabkan aterosklerosis. Terjadinya aterosklerosis dapat menyebabkan timbulnya inflamasi yang ditandai dengan meningkatnya kadar C-Reactive Protein (CRP) dalam darah. CRP merupakan salah satu protein fase akut yang meningkat selama inflamasi sistemik. Tujuan dari kegiatan ini untuk mengetahui gambaran C-Reaktif Protein penderita Hipertensi pada Masyarakat di Desa Bone Kecamatan Nekamese Kabupaten Kupang. Pelaksanaan kegiatan Pengabdian Masyarakat dilaksanakan di Desa Bone Kecamatan Nekamese dengan sasarannya adalah masyarakat Lansia yang menderita Hipertensi yang kemudian diperiksa kadar Creaktif proteinnya. Semua Lansia yang Hipertensi dilakukan pemeriksaan kadar C- Reaktif Proteinnya untuk menilai ada tidaknya terjadi inflamasi.Dari hasil pelaksanaan kegiatan disimpulkan bahwa semua Lansia hipertensi memiliki kadar C-Reaktif Protein yang normal. Hal ini disebabkan karena adanya kegiatan pemeriksaan Kesehatan rutin yang dilakukan oleh Puskesmas setempat sehingga status hipertensinya dapat dikontrol dengan baik.
Gambaran C-Reactive Protein Pada Pasien Tuberkulosis Paru di Puskesmas Naibonat Kabupaten Kupang Ni Ketut Yuliana Sari; Adrianus Ola Wuan; Aldiana Astuti; Novian Agni Yudhaswara; Agnes Rantesalu; Ikhsan Rasidin
Quantum Wellness : Jurnal Ilmu Kesehatan Vol. 1 No. 4 (2024): Desember: Quantum Wellness : Jurnal Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/quwell.v2i1.1280

Abstract

Tuberculosis is a chronic infectious disease induced by the bacterium Mycobacterium tuberculosis and can attack human organs, especially the lungs. The entry of this antigen causes the release of various pro-inflammatory cytokines which cause liver cells to synthesize acute phase proteins such as C-Reactive Protein (CRP). C-Reactive Protein is a type of alpha globulin protein that appears in the blood in response to inflammation in the body. The aim of this study was to determine the description of CRP in pulmonary tuberculosis patients at the Naibonat Community Health Center. The method used is descriptive with a cross sectional study design method. This research was carried out at the Naibonat Health Center Laboratory, Kupang Regency from February to April 2024. The examination method used was the qualitative latex agglutination method. The results of CRP examination on pulmonary TB patients from a total of 23 respondents obtained reactive results for 8 samples (35%) and non-reactive results for 15 samples (65%). Based on the results of reactive CRP, the highest number was found in males, 6 people (26%), while the highest number was found in the age range 12-25 years, 4 patients (Teenagers) (17%), with the highest length of treatment at 0 -2 months (intensive stage) as many as 6 patients (35%), with the highest patient status being new TB as many as 8 patients (35%), with the highest treatment status being non-resistant as many as 6 patients (26%).
Pemeriksaan C-Reactive Protein Sebagai Penanda Inflamasi dalam Upaya Awal Skrining Adanya Penyakit Menular Maupun Tidak Menular Pada Warga di Wilayah Binaan Desa Bone Kecamatan Nekamese Kabupaten Kupang Ni Ketut Yuliana Sari; Agustina W. Djuma; Novian Agni Yudhaswara; Adrianus Ola Wuan; Agnes Rantesalu
Jurnal Pelayanan Masyarakat Vol. 1 No. 4 (2024): Jurnal Pelayanan Masyarakat
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/jpm.v1i4.1076

Abstract

This community service activity was carried out in March 2024 in the fostered area of Bone Village, Nekamese District, Kupang Regency, located at the Gereja GMIT Tritunggal Pasneno, Bone. The activity carried out in the form of C-Reactive Protein (CRP) examination. CRP examination is a general inflammatory marker examination, so it can be a presumptive examination of inflammation in the body both caused by infectious and non-communicable diseases. The results of the examination of 43 samples showed reactive CRP as many as 2 samples (4.7%).
Screening Kadar Rheumatoid Factor (RF) Pada Lanjut Usia (Lansia) Dengan Keluhan Nyeri Sendi Adrianus Ola Wuan; Marni Tangkelangi; Wilhelmus Olin; Michael Bhadi Bia; Ni Ketut Yuliana Sari
Jurnal Pelayanan dan Pengabdian Masyarakat Indonesia Vol. 2 No. 2 (2023): Juni : Jurnal Pelayanan dan Pengabdian Masyarakat Indonesia
Publisher : Sekolah Tinggi Ilmu Administrasi Yappi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jppmi.v2i2.457

Abstract

Rheumatoid arthritis is an autoimmune disease that occurs when the body's immune system mistakenly attacks healthy joints. The disease can start at any age, but the likelihood of onset is highest in older adults. In Rheumatoid Arthritis the tissue lining the joints becomes thickened resulting in swelling and pain. Elderly is an age that has a greater possibility of having an autoimmune this is based on the statement that the older you are, the greater the chance of having an autoimmune. Early diagnosis and treatment isthe key to successful treatment of Rheumatoid Arthritis because joint damage cannot be restored once it occurs. Rhematoid Factor examination is largely used to help diagnose rheumatoid arthritis. Community service activities aim to determine the description of RF levels in the elderly with supply disorders, descriptive research type with a cross sectional approach. The sampling technique used purposive sampling as many as 62 elderly people in the Social Service of NTT Province. The results of RF examination in all elderly samples 6.45% have positive results and 93.55% negative results.
Penyuluhan Dan Praktik Perilaku Hidup Bersih Dilingkungan SD GMIT Bone Di Kecamatan Nekamese Kabupaten Kupang Dalam Mewujudkan Masyarakat Peduli Sehat Agnes Rantesalu; Ni Ketut Yuliana Sari; Novian Yudhaswara
Jurnal Pelayanan dan Pengabdian Masyarakat Indonesia Vol. 3 No. 2 (2024): Juni : Jurnal Pelayanan dan Pengabdian Masyarakat Indonesia
Publisher : Sekolah Tinggi Ilmu Administrasi Yappi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jppmi.v3i2.1301

Abstract

Health is a state of well-being, encompassing physical, mental, spiritual, and social aspects that enable individuals to live productively both socially and economically. Generally, in society, the understanding of clean living behaviors is still low due to a lack of information on the importance of clean living behaviors and the limited facilities that support them. Early introduction to clean living behaviors is crucial so that children become accustomed to practicing them. This community service activity is carried out to enhance the knowledge, awareness, willingness, and ability of the community, especially students of SD GMIT Bone, to engage in Clean and Healthy Living Behaviors (PHBS) and to provide facilities that enhance awareness of clean and healthy living. One way to prevent health problems is by educating children on how to wash their hands with soap and the importance of personal hygiene. The PHBS education and practice provided to children help increase their awareness of clean living behaviors and maintaining environmental cleanliness with the facilities provided.
Co-Authors Adrianus Ola Wuan Adrianus Ola Wuan Adrianus Olawuan Agnes Rantesali Agnes Rantesalu Agustina W. Djuma AHDIAH IMROATUL MUFLIHAH Aldiana Astuti Anas Fadli Wijaya Arista Day Atajama Bia, Michael Bhadi Ikhsan Rasidin MADE SUSUN PARWANAYONI Marni Tangkelangi Marni Tangkelangi Michael Bhadi Bia Michael Bhadi Bia Mutia Hariani Nurjanah Nelci Magdalena Tefa Neny Foekh Novian Aghni Yudhaswara Novian Agni Yudaswara Novian Agni Yudhaswara Novian Yudhaswara Nurdin, Kuntum Ekawati OLIN, WILHELMUS Rahmawati, Septyana Eka Retno Kawuri RIAN ANGGIA DESTIAWAN Sholihatil Hidayati Tuppak Sirait Wilhelmus Olin Wilhelmus Olin Wuan, Adrianus Ola YUANITA CLARA LUHI ROGALELI