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All Journal PHARMACON Jurnal Ilmu dan Teknologi Pangan Biofarmasetikal Tropis (The Tropical Journal of Biopharmaceutical) Majalah Info Sains Journal of Pharmaceutical and Sciences.
Jeane Mongi
Program Studi Farmasi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon, Tomohon, Indonesia.
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Journal : PHARMACON

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UJI EFEK EKSTRAK ETANOL DAUN KUCING-KUCINGAN (Acalypha Indica L.) TERHADAP KADAR GULA DARAH TIKUS PUTIH JANTAN GALUR WISTAR (Rattus novergicus) Kawatu, Cheryl; Bodhi, Widdhi; Mongi, Jeane
PHARMACON Vol 2, No 1 (2013): pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.2.2013.1017

Abstract

ABSTRACT The cooperleaf herb (Acalypha indica L.) is a plant which is used as a traditional medicine. The cooperleaf herb leave is a part of the plant to use for decreasing the blood sugar level. The aimed of this research is to know the giving effect of the cooperleaf herb leave ethanol extract to the blood sugar level of strain wistar white male mice which is inducted by sucrose. Fifteen strain wistar white male mice are divided into five treatment groups namely negative control group, positive control group, the group of the cooperleaf herb leave extract with doses 3,15 g extract/ kg body weight, 6,3 g extract/ kg body weight, and 12,6 g extract/ kg body weight. The data obtained from the examination  by sucrose and at 15, 30, 60, 120 minutes after gave treatment. The data are analyzed by using One Way ANOVA and to be continued with LSD test for seeing the differentiation between the treatments. The result of this research show the cooperleaf herb leave ethanol extract with with doses 3,15 g extract/ kg body weight, 6,3 g extract/ kg body weight, and 12,6 g extract/ kg body weight have the effect to decrease the blood sugar level of strain wistar white male mice.
FORMULASI SALEP EKSTRAK ETANOL DAUN NANGKA (ARTOCARPUS HETEROPHYLLUS LAM.) DAN UJI EFEKTIVITAS TERHADAP PENYEMBUHAN LUKA TERBUKA PADA KELINCI Hamzah, Hamdiyah; Fatimawali, Fatimawali; Yamlean, Paulina V. Y.; Mongi, Jeane
PHARMACON Vol 2, No 3 (2013): pharmacon
Publisher : PHARMACON

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Abstract

ABSTRACTJackfruit leaves is a plant that work as medicine on healing process of skin diseases,especially in wounds. The purpose of this study is to determine the quality of ointment fromethanolic extract of Jackfruit leaves at the concentration on 5%, 10% and 15% and the effectof the open wound healing in rabbits. Type of this research is laboratory experimental. In thisresearch maceration was done as the extraction method to got the extract of Jackfruit leaves.The ointment of ethanolic extract from jackfruit leaves made within 3 concentrations of 5%,10% and 15%. On the testing ointment using organoleptic test, homogenity test and pH test.The effectiveness assay to heal the open wounds using 5 groups, Betadine ointment (positivecontrol), basic ointment (negative control), the ointment of ethanolic extract from Jackfruitleaves 5%, 10%, and 15% of the 3 rabbits with a 1.5 cm was done and observed until 7 days.The data were processed statistically using One Way ANOVA (Analysis Of Variant) andfollowed by LSD (Least Significant Different). Results of this study showed that the ointmentof ethanolic extract from Jackfruit leaves on the concentration of 5%, 10% and 15% producequalified ointment of organoleptic test, homogenity test and pH test, also give the effect ofopen wound healing in rabbits and the most effective cure is the ointment of ethanolic extractfrom Jackfruit leaves 15%.Keywords: ethanolic extract of Jackfruit leaves, ointment, wound, rabbit.
UJI EFEK ANTIPIRETIK INFUSA DAUN SESEWANUA (Clerodendron squamatum Vahl.) TERHADAP KELINCI JANTAN YANG DIINDUKSI VAKSIN DTP HB Moot, Clementia Luigy; Bodhi, Widdhi; Mongi, Jeane
PHARMACON Vol 2, No 3 (2013): pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.2.2013.2379

Abstract

ABSTRACTSesewanua leaves (Clerodendron squamatum Vahl.) empirically used for an alternavite fevertreatment. The aims of this study was to investigate infuse of Sesewanua leaves hadantipyretic effectts for rabbits induced by vaccine DTP HB. This assay uses 15 rabbitsgrouped into 5 groups, the negative control (destilled water), the treatment (infuse ofSesewanua leaves 20%, 40% and 80%) and a positive (parasetamol). Rabbits induced pyrexiawith vaccine DTP HB doses 0,25ml/KgBB by intramuscular route. Rabbit’s rectaltemperature was measured every 1 hour until 4 hours after the oral administration. Thedecrease of rabbit’s rectal temperatur were analyzed by one way ANOVA and LSD test (α =0,05%). The result showed that infuse of Sesewanua in concentrates 20%, 40% and 80% hadantipyretics effect for rabbits induced by vaccine DTP HB.Keywords : Antipyretics effect test, Clerodendron squamatum Vahl., Vaccine DTP HB,rabbits
Co-Authors Adeanne C. Wullur Adinda Bee Aletheia Marvla Windi Tuda Aletheia Tuda Alfiano H. Mbaubedari Amal Ginting Amal Ginting Amal R. GInting Amal R. Ginting Anatasya Mongdong Andhika Ratu Asmuruf, Yunice Astrindo Maatiri Cheryl Kawatu Christin, Andriany M. Christine Mamuaja Clementia Luigy Moot Debora Christy Palit Douglas N. Pareta Einstein Z. Z. S. Karundeng Fatimawali . Febrilia Mangirang Ferdy A. Karauwan Filia Krisna Wilar Friska Mery Montolalu Geyza O. Samalagi Gideon A. R. Tiwow Ginting, Margaretha S. Giseli Margareth Tampa Hamdiyah Hamzah Hanna M. Rumagit, Hanna M. Hariyadi Hariyadi Hariyadi Hariyadi Hellen Matindas Hide Devid N. Sompotan Hizkia Rifka Warokka Ingriani Tan Djindadi Ivone Katiandagho Jabes Wolter Kanter Jeike Adondis Jekilian Sumati Popala Jessica I Mampouw Jessy Lintongan Johrawati Aritan Julia Brigita Sumonda Kalangi, Only Imando Karauwan, Ferdy Lengkey, Yessie M. Bayu Firmansyah, M. Bayu Marshella Mokoagouw Marzilano M. R. Rumagit Mawikere, Juliana Melda Melisa Paat Nerni Potolangi Olpin Tumole Olvie Datu Paat, Vlagia Indira Padoma, Chintya Pakingki, Priska Pangkei, Octry M. Pareta, Douglas Natan Paulina yamlean Polii, Ruland Priska Juanita Pakingki Rafen Ngama Rahmat S. Santoso Randy Tampa'i Randy Tampa’i Renault Marsidi Resa Setia Rocky Ardiles Lawere Royke R. Palandi Ryan Offeis Kolondam Salindeho, Netty Sambou, Christel N. Sarah Sambow Silvana L. Tumbel Simanjuntak, Alfared S. Sonny Untu Sony Larumpaa Sumangando, Adolfina Swingly Diego Songgigilan Tabita R. S. Rongkonusa Tampa'i, Randy Tendean, Augina C. Timburas, Mitra W. Tombuku, Joke Luis Trully O.S . Rumengan Tulandi, Selvana Stien Venly Y.D. Warouw Wantah, Kezia T. Widdhi Bodhi Wilmar Maarisit wong, kevin Yanti Paula Ranti Yappy F. Saroinsong Yulia Tresia Solosa Yuliana Polopadang Yusuf Tapehe