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PERAN AGEN REMINERALISASI PADA LESI KARIES DINI Yani Corvianindya Rahayu
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 10 No 1 (2013)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Remineralization is a natural repair process for caries lesions. It is now well-accepted that the primary modes of action of fluoride are enhancement of remineralization, inhibition of demineralization, and inhibition of plaque bacteria, with remineralization being the most important. This study to aimed to understanding the role of remineralization methods to alter mineral balance on management of non-invasive dental caries. Calcium and phosphate delivery can be enhanced to improve remineralization, especially in persons with reduced salivary function. There is a great need for improved and novel remineralization methods to alter the caries balance for the better, especially in individuals with a high cariogenic bacterial challenge. There was also influence of fluoride and carbonate on the remineralization process. Dentinal tubules were occluded by apatite crystallites is a feature also shared by transparent dentin beneath caries lesions and age-induced transparent dentin. It is based on unstabilized amorphous calcium phosphate (ACP), where a calcium salt and a phosphate salt are delivered intra-orally or delivered in a product with a low water activity. As the salts mix with saliva, they dissolve, releasing calcium and phosphate ions. The mixing of calcium ions with phosphate ions to produce an ion activity product for amorphous calcium phosphate that exceeds its solubility product results in the immediate precipitation of ACP or, in the presence of fluoride ions, amorphous calcium fluoride phosphate (ACFP). In the intra-oral en vironment, these phases (ACP and ACFP) are potentially very unstable and may rapidly transform into a more thermodynamically stable, crystalline phase (e.g., hydroxyapatite and fluorhydroxyapatite). However, before phase transformation, calcium and phosphate ions should be transiently bioavailable to promote enamel subsurface lesion remineralization.
Regulasi molekuler proses resorbsi alveolar pada gigi sulung Yani Corvianindya Rahayu
Makassar Dental Journal Vol. 2 No. 3 (2013): Vol 2 No 3 Juni 2013
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (421.708 KB) | DOI: 10.35856/mdj.v2i3.125

Abstract

Resorbsi akar gigi sulung merupakan proses fisiologis yang terjadi pada pergantian gigi permanen. Sel yang bertanggung jawab pada proses resorbsi tersebut adalah sel odontoklas. Dimana prekursor sel odontoklas tersebut menggalami differensiasi dan memberikan signal untuk memulai proses resorbsi gigi sulung. Makalah ini membahas mengenai mekanisme yang melibatkan proses resorbsi akar gigi fisiologis tanggalnya gigi sulung, oleh karena gigi permanen pengganti maupun yang agenisi serta regulasi molekuler pada proses resorbsi tersebut. Resorbsi akar gigi sulung diregulasi oleh sel retikulum dan folikel gigi permanen melalui sekresi molekul stimulator, seperti sitokin dan faktor transkripsi. Proses resorbsi akar gigi sulung diregulasi menyerupai proses remodeling tulang yang meliputi sistem reseptor ligand yang dikenal sebagai RANK/RANKL (aktivator reseptor dari inti faktor kappa B) Ligand (RANKL). Selain RANKL dan OPG, molekul lain seperti faktor transkripsi terlihat dalam aktivasi osteoklas dan pembentukan odontoblas.
Pelatihan Perilaku Hidup Sehat Pada Siswa Sekolah Luar Biasa Negeri Jember Banun Kusumawardani; Dwi Merry Christmarini Robin; Yani Corvianindya Rahayu; Parawita Dewanti; Siti Komariyah
Abdimas Universal Vol. 4 No. 2 (2022): Oktober
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Balikpapan (LPPM UNIBA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36277/abdimasuniversal.v4i2.233

Abstract

Healthy living behavior training is an effort to empower students of SLB Negeri Jember. The implementation of the training has been designed according to the abilities of the students. This activity has implemented the concept of improving life skills so that students are prevented from various diseases and are able to live healthy independently. The implementation method is as follows: 1) counseling and training on healthy living behavior and brushing teeth properly; 2) general health and oral health examinations; and 3) revitalization of School Health Unit through training of Student Health Cadres. Activities are equipped with modules and health examination record books. Activity evaluation procedures include: 1) re-examination of general health status; 2) re-examination of oral health status; and 3) supervision one month after program implementation. At the end of the activity, the students are able to wash their hands and brush their teeth properly and independently. Student Health Cadres are able to take measurements of height, weight, and body temperature. The general health profile of students is quite good, but their oral health is still poor and requires treatment from health workers.
Respons Antiinflamasi Serbuk Biji Alpukat(Persea Americana Mill) Terhadap Jumlah PMN Neutrofil Mencit yang Diinduksi Bakteri E. Coli Yani Corvianindya Rahayu
Jurnal Kedokteran Meditek vol. 16 no. 42 September-Desember 2009
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v16i42.195

Abstract

MITIGATION OF SOIL-TRANSMITTED HELMINTHIASES RESURGENCE IN THE ERA OF COVID-19 DISRUPTION: A LITERATURE REVIEW Falah, Pilar Menara; Yani Corvianindya Rahayu; Atik Kurniawati; Yudha Nurdian
Majalah Biomorfologi Vol. 32 No. 2 (2022): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v32i2.2022.96-102

Abstract

Highlights: 1.    Prolonged interruptions and delays that accompany the COVID-19 pandemic have further increased the spread of STH in high-transmission areas.2.    Adaptations carried out in the context of a pandemic are able to strengthen efforts to sustain deworming programs based on primary health facilities and their integration into community-based platforms.3.    Community-based WASH activities must be continued by adjusting WASH messages to focus on preventing the transmission of COVID-19. Abstract: Background: Interruptions and postponements are influencing people's desire for soil-transmitted helminthiases (STH) services as all countries are fighting the Covid-19 pandemic. The risk of spreading STH in high-transmitting areas increases with increased disturbance. Indonesia is a compatible host country for STH because it is a tropical country. The STH impacts the population's nutrient status and disturbs their cognitive processes. Objective: To describe the issue and how best efforts had been made to mitigate the possibility of a resurgence of intestinal worms during the disruptions caused by the Covid-19 pandemic. Material and Method: Search for the most recent articles in a database of research in January 2022 on Google Scholar, Science Direct, and PubMed. Qualifying articles were then extracted and synthesized qualitatively. Discussion: The interference and postponement of the deworming control program due to COVID-19 had a tentative effect on the progress of achieving the elimination of STH as a public health problem by 2030. Conclusion: Best practices show that revitalization efforts to control STH by strengthening integrated interventions and collaborations through the expansion of POPM, PHBS, and STBM in line with COVID-19 prevention efforts with mitigation innovations shifting from controlling morbidity to terminate the transmission of STH.
Peningkatan Pengetahuan Nilai Tambah Limbah Cangkang Pupa Black Soldier Fly Bagi Pembudidaya Maggot Kusumawardani, Banun; Rahayu, Yani Corvianindya; Joelijanto, Rudy; Handoyo, Tri; Dewanti, Parawita; Subchan, Wachju
Jurnal KARINOV Vol 7, No 2 (2024): Mei
Publisher : Institute for Research and Community Service (LP2M), Universitas Negeri Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17977/um045v7i2p136

Abstract

Proses penguraian sampah organik dengan biokonvertor Black Soldier Fly (BSF) dilakukan pada tahap larva, sehingga saat BSF menjadi lalat dewasa, bertelur dan mati akan meninggalkan limbah media bekas maggot, cangkang pupa dan bangkai lalat. Limbah media bekas maggot digunakan untuk bahan kompos, sedangkan limbah cangkang pupa dan bangkai lalat belum dimanfaatkan. Timbunan limbah cangkang pupa dan bangkai lalat setelah siklus hidup BSF dikhawatirkan bisa menimbulkan pencemaran udara dan lingkungan jika dibiarkan menumpuk di halaman rumah. Berdasarkan analisis situasi tersebut, tim ProbangDebi UNEJ bersama Bank Sampah Ekoliterasi Dermaku Jenggawah merancang kegiatan yang bertujuan untuk memberikan edukasi tentang teknologi pengolahan limbah cangkang pupa agar memiliki nilai ekonomi. Metode pelaksanaan kegiatan adalah edukasi potensi limbah cangkang pupa BSF dan pelatihan teknologi pengolahan limbah cangkang pupa BSF. Data pre-test dan post-test menunjukkan bahwa terjadi peningkatan pengetahuan pembudidaya maggot di Desa Jenggawah tentang pemanfaatan limbah cangkang pupa BSF menjadi produk yang memiliki nilai tambah. Pengolahan limbah cangkang pupa BSF dapat ditingkatkan kapasitasnya menjadi skala yang lebih besar lagi seiring dengan peningkatan kebutuhan pasar dalam pemanfaatan kitin dan kitosan. Selanjutnya, dibutuhkan pelatihan pemasaran melalui platform e-commerce dan koordinasi lintas sektoral untuk memberikan dukungan atas upaya pengolahan limbah menjadi produk yang bermanfaat bagi kesejahteraan dan perekonomian masyarakat. Kata kunci— Black Soldier Fly, Budidaya Maggot, Cangkang Pupa, Kitin, Kitosan Abstract The process of decomposing organic waste using the Black Soldier Fly (BSF) bioconverter is carried out at the larval stage. BSF becomes adult flies, lay eggs and die, which will leave maggot cultivation media, pupa shells and fly carcasses. Maggot cultivation media is used as compost material, while pupa shells and fly carcasses have not been utilized. Piles of pupa shells and fly carcasses can cause air and environmental pollution. The ProbangDebi UNEJ team and the Dermaku Jenggawah Ecoliteracy Waste Bank designed activities aimed at providing education on pupa shell processing so that it has economic value. The implementation method is education and training on BSF pupa shell processing technology. Pre-test and post-test data show that there has been an increase in the knowledge of maggot cultivators in Jenggawah Village regarding the use of BSF pupa shells into products that have added value. BSF pupa shell processing capacity can be increased to a larger scale in line with increasing market demand for the use of chitin and chitosan. Furthermore, marketing training through e-commerce platforms and cross-sectoral coordination is needed to provide support for efforts to process waste into products that are beneficial for the welfare and economy of the community. Keywords— Black Soldier Fly, Chitin, Chitosan, Maggot Cultivation, Pupa Shell
The Effect of cocoa pod husk (Theobroma cacao L.) extract on alveolar socket post tooth extraction Rahayu, Yani Corvianindya; Yuwono, Budi; Syafriadi, Mei; Amin, Muhammad Nurul; Kumala, Efa Ayu Ratnaning
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 1 (2025): March
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i1.p37-44

Abstract

Background: Cocoa pod husk (CPH) of Theobroma cacao L. contains tannins, alkaloids, saponins, and flavonoids triterpenoids that have antibacterial, anti-inflammatory, and antioxidant activities that can accelerate wound healing and alveolar bone regeneration. Purpose: This study aimed to analyze the effect of CPH extract gel on the number of fibroblasts, osteoblasts, and osteoclasts in Wistar rats’ sockets after tooth extraction.  Methods: The samples used were 36 male Wistar rats divided into three groups: the negative control group (placebo gel), the positive control group (Alveogyl; Septodont, UK), and the treatment group (100 mg/ml CPH extract gel), which in each application was given for three, seven, and fourteen days on the mandibular first molar post-extraction socket. The samples were sacrificed and tissue was processed on days 4, 8, and 15. The amount of fibroblasts, osteoblasts, and osteoclasts was identified and determined by the Image J software. Results: The Mann-Whitney U analysis showed significant differences (p<0.05) between groups. Fibroblasts and osteoblasts in the treatment group were significantly higher than the control groups. Osteoclasts in the treatment group were significantly lower than the control group. Conclusion: Ethanol extract gel of CPH significantly increased fibroblasts on days 3 and 5 and osteoblasts on days 7 and 14 and decreased osteoclasts on day 14 in post-extraction socket of Wistar rats.
Correlation between general health, nutrition, and oral health status of elderly in a typical retired community-house Kusumawardani, Banun; Dharmayanti, Agustin Wulan Suci; Robin, Dwi Merry Christmarini; Rahayu, Yani Corvianindya; Fitriyana, Nurul Isnaini
Padjadjaran Journal of Dentistry Vol 33, No 2 (2021): July 2021
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol33no2.18950

Abstract

Introduction: Indonesia is in an aging population era marked by an increase in elderly population above 7%. An enhancement of elderly population presents health problems due to organ function deterioration and requires extraordinary attention. General health, nutrition, and oral health status are the most problems claimed by elderly, particularly retired. Objective of this study was to analyze the correlation between the general health, nutrition, and oral health status of elderly. Methods: Analytical descriptive research with cross sectional method was carried out on 36 respondents in Paguyuban Purnabakti, Patrang, Jember, East Java Province. The sampling was done by purposive sampling. Information about social-demography and general health status of respondents were obtained from the questionnaire. The social-demography investigation comprised sex, age, education level and status of residence. While general health observation, it comprised smoking status, general check-up, presence of systemic diseases, blood pressure and blood biochemical parameters.[CS1]  Nutritional status was examined by body mass index (BMI). Oral examination for identifying oral health status included the number of the teeth remaining in the oral cavity, use of dentures, oral hygiene index (OHI-s), and periodontal tissue health (CPITN). Results: The result exhibited that most of the respondents presented good general health status. However, there was no significant correlation between routine general health observation and age (p=0.906). Moreover, there was no significant relationship between blood biochemical profile (blood glucose, total cholesterol, and blood pressure level) with nutrition status (p=..., p=..., and p=... respectively), and oral health status (p=...), except with oral hygiene (p=...). Conclusion: This study is limited to Paguyuban Purnabakti, Patrang, Jember, East Java Province. Although this study could not be generated in all communities, this study concluded no relationship between general health (smoking, systemic disorders, and routine general health observation), nutritional status, and oral health in the elderly. [CS1]Disesuaikan dengan table 2
The role of purple leaves extract (Graptophyllum Pictum (L.) Griff) on the number of fibroblasts and blood vessels in the socket after tooth extraction Kurniawati, Atik; Kristanti, Yuli Dwi; Rahmat, Naila Azifatur; Rahayu, Yani Corvianindya; Cholid, Zainul; Sosiawan, Agung
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 1 (2024): March
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i1.p56-61

Abstract

Background: Tooth extraction is the process of removing teeth from the alveolus. It will leave a mark on the socket and surrounding soft tissue. One of the cells that plays an important role in the wound healing process after tooth extraction is fibroblasts. When an injury occurs, some blood vessels are damaged; therefore, new blood vessels need to form. Purple leaves extract could be an alternative treatment for wound healing after tooth extraction as it contains flavonoids, saponins, alkaloids, steroids, and tannins. Purpose: The study aimed to analyze the role of purple leaves extract on the increase in fibroblasts and blood vessels in the socket after tooth extraction in Wistar rats. Methods: The method used was a laboratory experiment with a post-test-only control group design. The samples used were 24 rats divided into two groups: the control group, which was given aquadest, and the treatment group, which was given 1.5 mL of purple leaves extract with 10% concentration by sondage. Tissue preparations were used to count fibroblasts, and blood vessels were counted and observed on the 3rd, 5th, and 7th days. Results: Statistical tests showed a significant difference in the number of fibroblasts and blood vessels between the control and treatment groups on days 3, 5, and 7. Conclusion: Purple leaves extract could increase the number of fibroblasts and blood vessels in the tooth socket after tooth extraction of Wistar rats.
Analysis of antioxidant and antibacterial activity of cocoa pod husk extract (Theobroma cacao L.) Rahayu, Yani Corvianindya; Setiawatie, Ernie Maduratna; Rahayu, Retno Pudji; Ramadan, Doaa Elsayed
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 4 (2023): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i4.p220-225

Abstract

Background: Theobroma cacao bean manufacturing worldwide includes undesired byproducts such as cocoa pod husks. Cocoa pods contain a variety of beneficial chemicals, including polyphenols. Polyphenols have a vital function in the treatment of many illnesses and infections of the oral cavity. This is due to their vital qualities in the oral cavity, including anti-inflammatory, antibacterial, and antioxidant actions. Purpose: The goal of this study was to look at the antioxidant content and antibacterial activity of cocoa pod husk extract (Theobroma cacao L.) against Phorphyromonas gingivalis (P. gingivalis) and Streptococcus mutans (S. mutans). Methods: Cocoa pod husk extract was produced using an ultrasonic homogenizer and 70% ethanol. Thin layer chromatography and the Folin–Ciocalteu test were used to determine the phytochemical content and total phenolic content of the extract. The 2,2-diphenyl-1-picryl-hydrazyl-hydrate technique was used to measure antioxidant activity. Minimum inhibitory concentration (MIC) tests were used to measure the antibacterial activity of ethanolic extract at concentrations of 1, 4, 8, 16, 32, and 64 mg/ml using a deep-well broth microdilution technique. Results: The presence of alkaloids, flavonoids, tannins, saponins, and triterpenoids was discovered in the cocoa pod husk extract. Conclusion: The antioxidant activity of the extract was significant (IC50 = 62 ppm), and the MIC of P. gingivalis and S. mutans was 16 mg/ml and 8 mg/ml, respectively.