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All Journal Dimas: Jurnal Pemikiran Agama untuk Pemberdayaan Pendidikan Matematika Jurnal Kimia Riset JURNAL KONSELING GUSJIGANG Chimica et Natura Acta Jurnal Agrotek UMMat Jurnal Kartika Kimia JURNAL FARMASI GALENIKA Akuntansi : Jurnal Akuntansi Integratif Jurnal Ilmiah Profesi Pendidikan Jurnal Farmagazine Journal of Biology Learning Jurnal Abdimas Kartika Wijayakusuma Jurnal Manajemen DIVERSIFIKASI Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Journal of Agritechnology and Food Processing TERAPUTIK: Jurnal Bimbingan dan Konseling JURNAL ILMIAH PENELITIAN MAHASISWA Inaba of Community Services Journal Science, Technology, and Communication Journal Jurnal Farmasi Galenika Scripta Economica: Journal of Economics, Management, and Accounting
Dewi Kurnia
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Public Health Social Sciences Other

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Journal : Jurnal Agrotek UMMat

 1 
Aktivitas antioksidan dengan metode cuprac dan penetapan kadar fenolat total pada ekstrak dan fraksi makroalga Eucheuma cottonii Kurnia, Dewi; Rohmah, Desita; Anggraeni, Vina Juliana
Jurnal Agrotek Ummat Vol 9, No 4 (2022): October
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jau.v9i4.11116

Abstract

Antioxidants are compounds that can counteract free radicals. The macroalgae Euchema cottonii belongs to a type of seaweed from the Rhodophyta which is thought to have antioxidant activity. In this study, the antioxidant activity was tested using the CUPRAC method using spectrophotometry at 450 nm and the determination of total phenolic compounds in the extract and macroalgae fraction Eucheuma cottonii using the Folin Ciocalteu method. The extraction method was carried out using the maceration method with 70% ethanol and fractionation using ECC with n-hexane, ethyl acetate, and methanol-water (20% v/v). The results of TLC monitoring of Eucheuma cottonii showed the presence of flavonoid compounds, phenols, alkaloids, steroids, and triterpenoids. The results of the antioxidant activity test showed that the EC50 for the ethanol extract and the n-hexane, ethyl acetate, and methanol-water fractions were 89.11; 143.40; 100.02 and 90.22 g/ml respectively with EC50 vitamin C as a comparison of 6,86 g/ml. The results of the determination of the total phenolate content of the ethanol extract and the fractions of n- hexane, ethyl acetate, and methanol-water were 2.77; 1.96; 2.76; and 3.09 mg/GAE per 100 mg extract. The ethanol extract had a strong antioxidant activity with an EC50  89.11 g/ml and the highest total phenol content was in the methanol-water fraction of 3.09 mg/GAE per 100 mg extract. The results showed that the ethanolic extract of the macroalga Eucheuma cottonii has the potential as an alternative source of antioxidants.
Aktivitas antibakteri ekstrak dan fraksi makroalga Eucheuma cottoni terhadap bakteri penyebab jerawat Kurnia, Dewi; Suhardiman, Aris; Nurdiansyah, Hedy; Ghazali, Mursal
Jurnal Agrotek Ummat Vol 9, No 2 (2022): April
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jau.v9i2.6161

Abstract

Acne is a skin disease that often occurs in adolescence and even adulthood, characterized by the presence of blackheads, papules, pustules, nodes, and cysts on the face, neck, upper arms, chest, and back. Although not life-threatening, acne can affect a person's quality of life by giving a bad psychological effect in the way a person assesses, perceives and responds to his condition and situation. The aim of this study is to asses the antibacterial activity of the extract and fraction of the macroalgae Euchema cottonii against acne-causing bacteria, namely Propionibacterium acnes and Staphylococcus epidermidis. The extraction method used was maceration, using 96% p.a ethanol as a solvent and fractionation using the ECC method with three solvents with different polarity levels, namely n-hexane, ethylacetate and ethanol. The activity test was carried out using the paper disc and micro dilution method with the comparison antibacterial clindamycin. The results showed that there was no antibacterial activity from either the extract or fraction of macroalgae Euchema cottonii against the bacteria Propionibacterium acnes, but there are activity from the extract and fraction (n-hexane and ethylacetate) against the Staphylococcus epidermidis bacteria with the MBC value at a concentration of 15% and MIC at a concentration of 5% (for the extract and n-hexane fraction), while for the ethylacetate fraction the MIC value was at a concentration of 10%. Therefor, the strength of the antibacterial activity of the extract and fraction of Eucheuma cottoni is in the weak category.
Co-Authors Abdullah, Hewa Yaseen Aiyi Asnawi Ali Imran Amelia, Sintia Andi Besse Tenriawaru Andriansyah, Ivan Anggraeni, Vina Juliana Aris Suhadirman Ashey Yuniar Budiana, Wempi Budiana, Wempi Dadih Supriadi, Dadih Deden Indra Dinata, Deden Indra Destrinelli Destrinelli Diana, Nana Ellin Febrina Emma Emawati Emma Emawati, Emma Evidawati, Evidawati Fitri Bella Mustika Sari Hamdi, Muhammad Harahap, Nur Hasanah Hutasoit, Lestari Idar Idar idar idar Idar, Idar Idar, Idar Irma Irma Juandi Juandi KOSASIH KOSASIH, KOSASIH Lia Marliani Lukitasari, Leni Magfiratul Jannah Mardhiani, Yanni Dhiani Moh. Taufik Saidul Akbar Muhammad Sofwan Nadya Prisdayanti Nurani Hafsyah Nurdiansyah, Hedy Nurjanah, Tina Siti Prika Aprilliana, Dhea Putri Ayu Rahayu, Kiki Dwi Rasimin Rasimin, Rasimin Rohmah, Desita Roni, Asep Roni, Asep Rum, Ira Adiyati Sabrina Wiyanpuri, Rahma Saktioto Saktioto Saputra, Muhammad Deni Sari, Putri Aprilia Silviana, Lilis Sinta Purnamasari Sintia Amelia Suhardiman, Aris Sukmawati, ika kurnia Suryadi Suryadi Syamsiar, Syamsiar Syamswisna , Umaro, Syifa Qudwatul Villia Anggraini Wiwik Handayani Yateno Yateno Yupapin, Preecha Zakiyah, Farah Zeily Nurochman Ziska, Rahma Zomiliarif Zomiliarif Zomiliarif