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All Journal Medical Journal of Indonesia Damianus Journal of Medicine The Indonesian Biomedical Journal Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Jurnal Ilmiah Kesehatan Jurnal Kesmas dan Gizi (JKG) Jurnal Ilmiah Kebidanan Indonesia (Indonesian Midwifery Scientific Journal) Cermin Dunia Kedokteran Khazanah: Jurnal Mahasiswa Indonesian Journal of Cancer eJournal Kedokteran Indonesia Griya Widya: Journal of Sexual and Reproductive Health Jurnal Kesehatan Cendikia Jenius Journal of Applied Holistic Nursing Science JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Cermin Dunia Kedokteran Journal of Health and Therapy
Fitriyadi Kusuma
Departement Of Obstetrics And Gynecology, Faculty Of Medicine, Universitas Indonesia - RSUPN Cipto Mangunkusumo
Religion Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Peran sentinel node pada kanker ginekologi Fitriyadi Kusuma; Marshaly Safira Masrie; Geraldus Sigap Gung Binathara; Abdul Hafiidh Surya Putra; Kemal Akbar Suryoadji
Journal of Health and Therapy Vol. 5 No. 2 (2026): Journal of Health and Therapy
Publisher : Nur Science Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53088/jht.v5i2.2371

Abstract

This review evaluated the role of sentinel lymph node mapping in early-stage gynecologic cancers, cervical, endometrial, and vulvar, as a staging approach that balanced diagnostic accuracy and patient safety. The search methods assembled evidence from major clinical trials and cohort studies on detection performance, diagnostic accuracy, and surgical morbidity compared with systematic lymphadenectomy. The findings indicated that this mapping achieved high detection rates with adequate sensitivity and reduced operative time, blood loss, and risks of lymphedema, lymphocele, and neurovascular injury. In cervical and endometrial cancer, multicenter and prospective studies demonstrated comparable oncologic safety alongside lower postoperative complications, whereas in vulvar cancer, a strategy based on a negative sentinel node reduced groin morbidity without compromising disease control in selected lesions. Tracer approaches, including radioisotopes, blue dye, and indocyanine green fluorescence, together with enhanced assessment through in-depth histopathology, supported broad clinical adoption. Overall, this review concluded that sentinel lymph node mapping was appropriate for routine use in suitable cases, provided bilateral mapping and standardized pathological evaluation.
Impact of Chemotherapy on Venous Thromboembolism in Cervical Cancer: Systematic Meta-Analysis Observational Studies Fitriyadi Kusuma; Kemal Akbar Suryoadji; Wulyo Rajabto; Geraldus Sigap Gung Binathara; Shuffa Chilla Mayhana; Fahrayhansyah Muhammad Faqih; Bintang Wirawan; Abdul Hafiidh Surya Putra
Jurnal Kesehatan Cendikia Jenius Vol. 3 No. 2 (2026): April 2026
Publisher : CV. CENDIKIA JENIUS INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70920/jenius.v3i2.373

Abstract

Objective: Cervical cancer is associated with an increased risk of venous thromboembolism (VTE), which may be further aggravated by chemotherapy. This study aimed to assess the impact of chemotherapy on VTE incidence in patients with cervical cancer. Methods: A systematic review was conducted according to PRISMA 2020 guidelines. PubMed, the Cochrane Library, and EMBASE were searched from inception to October 2024 for observational studies reporting VTE incidence in cervical cancer patients receiving chemotherapy. Studies including women with cervical cancer treated with chemotherapy and reporting VTE outcomes were eligible, while studies evaluating radiotherapy or surgery alone were excluded. Results: Three observational studies involving 2,292 patients met the inclusion criteria. Pooled analysis showed that chemotherapy significantly increased VTE risk (RR 2.83; 95% CI: 2.05–3.90; p < 0.001), with low statistical heterogeneity. The reported incidence of chemotherapy-associated VTE ranged from 10.0% to 18.7%. Conclusion: Chemotherapy is associated with a nearly threefold increased risk of VTE in cervical cancer patients. These findings support routine VTE risk stratification prior to chemotherapy and consideration of individualized thromboprophylaxis. Further prospective studies are needed to define optimal prevention strategies.
Tinjauan Kebijakan pada Rencana Aksi Nasional Eliminasi Kanker Leher Rahim sebagai Pencegahan Primer Kanker Serviks di Indonesia: Perspektif Vaksinasi HPV berdasarkan Rekomendasi Pusat Pengendalian dan Pencegahan Penyakit: Tinjauan Pustaka Kusuma, Fitriyadi; Suryoadji, Kemal Akbar
Cermin Dunia Kedokteran Vol 53 No 07 (2026): Juli 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i07.1675

Abstract

Introduction: Cervical cancer is the second most prevalent cancer among women in Indonesia and ranks third globally. It accounts for 7.5% of cancer-related deaths worldwide, with a notable impact in developing nations like Indonesia. The primary cause is high-risk Human Papillomavirus (HPV); however, the risk can be lowered through vaccination. This review aims to evaluate Indonesia's policy for implementing a national HPV vaccination program targeting school-aged children and assess its conformity with CDC guidelines. Methods: The study involved an extensive review of literature, as well as international and Indonesian policy documents. Results: The CDC recommends HPV vaccination for individuals aged 9-26, ideally beginning at 11 or 12 years old. In line with this, Indonesia has included the HPV vaccine in its national immunization schedule. The Indonesian Ministry of Health intends to require HPV vaccination for school-aged children, aiming for full national implementation by 2023. This reflects Indonesia's strong commitment to a comprehensive cervical cancer prevention strategy. The policy's alignment with CDC recommendations emphasizes the country's dedication to primary prevention through HPV vaccination. Conclusion: By enforcing HPV vaccination for school-aged children, Indonesia aims to substantially decrease the incidence and mortality rates associated with cervical cancer. This policy represents a significant advance in the fight against cervical cancer in Indonesia and could serve as a model for other countries contending with similar public health issues.
Factors That Influence Endometriosis to Become a Malignancy: A Narrative Review Fitriyadi Kusuma; Marshaly Safira Masrie; Kemal Akbar Suryoadji
Indonesian Journal of Cancer Vol. 20 No. 1 (2026): March
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v20i1.1431

Abstract

Endometriosis frequently affects women of reproductive age, and epidemiologic studies suggest it may be linked to an elevated risk of malignancy. Specific histopathological criteria characterise endometriosis-associated malignancy (EAM). Endometriosis-associated ovarian cancer (EAOC) accounts for about 80% of EAM occurrences, with the remaining 20% occurring outside the ovaries. Genetic mutations, including PTEN, ARID1A, and p53 alterations, are identified in endometriosis and EAM. Factors such as postmenopausal status, older age, and hypoestrogenic conditions have also been linked to higher risks of EAM and EAOC. Due to EAM's rarity, comprehensive data remains limited. This review examines current EAM research, focusing on EAOC and its clinical relevance.
Co-Authors Abdul Hafiidh Surya Putra Abdul Hafiidh Surya Putra Abdullah, Muhammad Raoul Taufiq Adib Kamil Putra Kadarusman Adiyarianni, Ghina Ahmad Fauzi Alexander AW Peters Alifaturrasyid Syafaatullah Ridwan Alifaturrasyid Syafaatullah Ridwan Amalia, Ginva Andi Darma Putra Andrijono Andrijono Anggaraeni, Tricia Dewi Ani Retno Prijanti Anisa Saphira Wulandari Aria Kekalih Arini Setiawati As’syifa, Salsa Billa Bambang Sutrisna Binathara, Geraldus Sigap Gung Bintang Wirawan Bintang Wirawan Darmiati, Sawitri Elfahmi, Khalida Ikhlasiya Tajdar Gefariena Fadhly, RM Ali Fahrayhansyah Muhammad Faqih Fahrayhansyah Muhammad Faqih Faisha Rahma, Melly Fauzi Ahmad Muda Ferry Sandra Fiastuti Witjaksono Garry Soloan Gatot Purwoto Geraldus Sigap Gung Binathara Geraldus Sigap Gung Binathara Geraldus Sigap Gung Binathara Geraldus Sigap Gung Binathara Hadinata, Valencia Hariyono Winarto Hellyanti, Tantri Iwan Darmansjah Jan Susilo Joedo Prihartono Junita Indarti Kadarusman, Adib Kamil Putra Kartiwa Hadi Nuryanto Kemal Akbar Suryoadji Kemal Akbar Suryoadji Kemal Akbar Suryoadji Kemal Akbar Suryoadji Kemal Akbar Suryoadji Kemal Akbar Suryoadji Kemal Akbar Suryoadji Kieran Pasha Ivan Sini Laila Nuranna Laila Nuranna Liedapraja, Mediana s. Lisnawati Liva Wijaya Malano, Yoarva Marshaly Safira Masrie Marshaly Safira Masrie Marshaly Safira Masrie Marshaly Safira Masrie Metasyah, Namira Michael Adrian Muhammad Haekal Muhammad Haekal Muhammad Ilyas Mutiara Riani Nadia Ayu Mulansari Nasution, Hiro Hidaya Danial Oktalia, Arisda Oni Khonsa Purnomo Hyaswicaksono Putra, Abdul Hafiidh Surya Ridwan, Alifaturrasyid Syafaatullah Rizky Humairah , Inas Sahat B. Matondang Salsa Billa As’syifa Sekarutami, Sri Mutya SEPTELIA INAWATI WANANDI Shuffa Chilla Mayhana Sini, Kieran Pasha Ivan Siregar, Trifonia Pingkan Sitorus, Christina Soloan, Garry Sri Mutya Sekarutami Stascia, Stefani Surahman Hakim Surahman Hakim Surya Putra, Abdul Hafiidh Suryoadji, Kemal Akbar Tofan Widya Utami Tofan Widya Utami Tricia Dewi Anggraeni Tsaniya Meidini Tahsya Hermawan Utami, Tofan Widya Vira Nur Arifa Vira Nur Arifa Widya Utami, Tofan Wulandari, Anisa Saphira Wulyo Rajabto Zahra, Reihana