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All Journal Jurnal Ilmiah Farmasi Pharmascience Berkala Kedokteran Dinamisia: Jurnal Pengabdian Kepada Masyarakat Journal of Midwifery and Nursing JURNAL PENDIDIKAN MIPA Jurnal Pengabdian Kepada Masyarakat (Mediteg) Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Borneo Journal Of Pharmascientech Sasambo Journal of Pharmacy Jurnal Pengabdian Ilung (Inovasi Lahan Basah Unggul) Makara Journal of Science Jurnal Pengabdian Masyarakat Panacea Jurnal Sains dan Kesehatan
Nashrul Wathan
Lambung Mangkurat University
Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Studi Fitokimia Jamur Endofit Tumbuhan Seluang Belum (Luvunga sarmentosa (Blume) Kurz) Asal Kabupaten Tabalong Kalsel Nashrul Wathan; Pratika Viogenta; Jehan Azizah; Fery Ramadhan; Sindwi Rinanda Sari
Jurnal Pharmascience Vol 10, No 1 (2023): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v10i1.14317

Abstract

Seluang belum adalah tumbuhan asal Kalimantan yang dipercaya oleh masyarakat sekitar sebagai afrodisiaka karena memiliki metabolit sekunder yang bervariasi. Endofit adalah mikroba yang hidup di dalam jaringan tumbuhan dan mampu menghasilkan metabolit sekunder yang serupa dengan inangnya. Tujuan dari penelitian ini adalah mendapatkan isolat jamur endofit dari akar Seluang belum (Luvunga sarmentosa (Blume) Kurz.) dan melakukan skrining fitokimia senyawa yang dikandungnya. Proses penumbuhan isolat jamur endofit dari akar seluang belum (L. sarmentosa) dilakukan pada media Potato Dextrose Agar (PDA) hingga didapatkan isolat terpisah. Jamur endofit murni yang dihasilkan kemudian diamati identitasnya secara makroskopik dan mikroskopik. Jamur endofit hasil isolasi lalu dibiakkan dalam media Potato Dextrose Broth (PDB), senyawa bioaktif yang terkandung lalu diekstraksi menggunakan etil asetat dan dilanjutkan identifikasi senyawa fitokimianya. Penelitian ini mendapatkan 6 isolat endofit yang diidentifikasi sebagai Rhizoctonia solani, Corynespora citricola Ellis, Arthrobotrys oligospora Fresenius, Alternaria Nees:Fr., Phytophthora capsici dan Tripospermum Speg. Kandungan senyawa fitokimia yang diskrining dari ekstrak etil asetat keenam jamur endofit hasilnya beberapa isolat positif mengandung golongan senyawa fenolik, flavonoid, steroid, dan terpenoid. Kata Kunci: Saluang Bilung, lavanga sarmentosa, Fungi Endofit, Herba Kalimantan, Suku Dayak   Seluang belum. is a plant from Kalimantan which commonly believes by local people as an aphrodisiac because it has various secondary metabolites. Endophytes are microbes that live in plant tissues and are able to produce secondary metabolites similar to their host. The purpose of this study is to isolating the endophytic fungus from Seluang belum (Luvunga sarmentosa (Blume) Kurz) root and to perform phytochemical screening of its metabolites. Endophytic fungi isolated from seluang belum roots then grown in PDA (Potato Dextrose Agar) media until obtained separate isolates. The obtained fungal isolates then identified macroscopically and microscopically to determine their identity. The isolated fungi then fermented in PDB (Potato Dextrose Broth) media, the secondary metabolites then extracted with ethyl acetate and identified its phytochemicals. The results showed that 6 endophytic isolates were identified as Rhizoctonia solani, Corynespora citricola Ellis, Arthrobotrys oligospora Fresenius, Alternaria Nees:Fr., Phytophthora capsici and Tripospermum Speg. The phytochemical content that screened from the ethyl acetate extract of 6 endophytic fungi was resulting some positive containing groups of phenolic compounds, flavonoids, steroids, and terpenoids.
Total Flavonoids Determination and Antioxidant Activity of Ethyl Acetate, Ethanol, and Methanol Extracts from Seluang Belum Root (Luvunga sarmentosa (Blume) Kurz.) Nashrul Wathan; Muhammad Ikhwan Rizki; Amalia Khairunnisa; Hilneser Simamora
Berkala Kedokteran Vol 19, No 1 (2023)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v19i1.15733

Abstract

Abstract: Flavonoids are phenolic compounds from nature that found in almost all parts of the plants. Seluang belum (Luvunga sarmentosa (Blume) Kurz.) root is one of the medicinal plants used by Dayak people in Central and South Kalimantan where in previous studies its part was contains flavonoids. This study aims to evaluate the best solvent for extracting flavonoid content and antioxidant activity using ethanol, methanol and ethyl acetate. The antioxidant activity performed by in vitro technique by DPPH assay. Total flavonoids content on the extracts of L. sarmentosa root determined using UV-Vis spectrophotometric with aluminium chloride method and calculated as quercetin equivalents (QE). The results showed the highest antioxidant activities confirmed for the methanol extract (IC50 = 80.33 ppm). The highest of total flavonoids contents was recorded for the ethanol extract (6.56 ± 0.006% w/w Quercetin Equivalent). The results showed that treatment effect of different solvent extraction was significant (sig <0.05) on total flavonoid and antioxidant activities from L. sarmentosa root.
Evaluasi Pengelolaan Obat di Puskesmas Terminal Kota Banjarmasin Tahun 2021 Sariah Sariah; Yodi Fernanda; Rahmi Annisa; Nashrul Wathan
BORNEO JOURNAL OF PHARMASCIENTECH Vol 6 No 2 (2022): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v6i2.432

Abstract

Drug management at a public health center is an important indicator of the quality of pharmaceutical services as it determines the success of its management. Drug management activities at a public health service involve aspects of planning, requesting, receiving, storing, distributing, destroying, controlling, as well as recording and reporting. This activity aims to ensure that drugs can be managed optimally to ensure the correct amount and type of pharmaceutical supplies in an effort to achieve the goals set at various levels of the work unit. This research aimed to evaluate drug management at Terminal public health center in Banjarmasin. The parameters used were accuracy of drug planning, compatibility of available drug items with DOEN 2021, percentage of drugs not prescribed for 6 months, and ercentage of expired or damaged drugs. This research was a descriptive non-experimental research conducted qualitatively using retrospective data, namely RKO and LPLPO from the period of January–December 2021. The results showed the evaluation of drug management at Terminal public health center in Banjarmasin, respectively: accuracy of drug planning (68%), compatibility of available drug items with DOEN 2021 (54%), drugs not prescribed for 6 months (18%), and expired or damaged drugs (4%). Based on these results, it could be seen that the drug management system at Terminal public health center in Banjarmasin hasn’t met the established standards.
ETNOBOTANI TUMBUHAN OBAT OLEH WARGA DAYAK MERATUS DI DESA GUNUNG RIUT KABUPATEN BALANGAN KALSEL Nashrul Wathan; Rina Rina; Nadia Rahmah; Hilya Aulia; Nita Pujianti
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 8 No 1 (2023): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jpx.v8i1.2904

Abstract

Traditional knowledge about the use of medicinal plants owned by various indigenous Dayak tribes in Kalimantan reflects that people's lives cannot be separated from the surrounding natural resources, especially medicinal plants. The purpose of this study was to determine the types of medicinal plants, the percentage of medicinal plant parts used and to determine how to process and use medicinal plants by traditional healers of the Dayak Meratus tribe in Gunung Riut Village. Informants are determined by purposive sampling technique. The result of the interview showed 28 species and divided into 18 families of medical plants used to treat toothache, back pain, skin diseases, fever, influenza, syphilis, fractures, wounds, hypertention, jaundice, malaria, hemorrhoids, increase stamina, laxative, asthma and indigestion. The percentage of plant parts that are widely used are leaves (26.67%), roots (23.33%), and stems (13.33%). Processing methods by soaking, boiling, pounding, without processing, squeezing, heating, cutting and burning. How to use by applying, massaging, sticking, drinking, pinching, bathing, and eating.
Cox2 Inhibitor Test Of Limpasu (Baccaurea Lanceolata) Using Computation Method Samsul Hadi; Nashrul Wathan; Deni Setiawan; Pratika Viogenta; Kunti Nastiti
Journal of Midwifery and Nursing Vol. 5 No. 3 (2023): September: Health Science
Publisher : Institute Of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/jmn.v5i3.4104

Abstract

The use of anti-inflammatory drugs with the COX-2 method is starting to develop tolerance, so that drugs circulating in the community now cause various kinds of complaints, namely inhibition of blood clotting and stomach ulcers. Therefore, the purpose of this study was to screen natural product compounds that have potential as COX-2 inhibitors. The materials used are compounds contained in B.lanceolata and COX-2 enzymes with code 3ln1 obtained from the RCSB database, the equipment used is a windows laptop with PLANT and discover studio software, the method used in this study is a computational study using docking software . The results in this study were that the docking score of B. lanceolata was higher than the native ligand, so the effectiveness was weaker than the native ligand, the docking scores obtained were as follows: Epidihydrotutin (-50.243); Sapidolide A (-51052); Melatonin (-53039); 6'-O-Vanilloylisotachioside (-60.910) and 6'-O-Vanilloyltachioside (-61.131). In conclusion, 6'-O-Vanilloyltachioside is a potential compound as a COX-2 inhibitor from B.lanceolata.
Skrining Inhibitor Antihistamin Secara In Silico dari Senyawa Melati Belanda (Quisqualis indica L.) Nashrul Wathan; Samsul Hadi; Rizki Swastika Puri
JURNAL PENDIDIKAN MIPA Vol 13 No 3 (2023): JURNAL PENDIDIKAN MIPA
Publisher : Pusat Publikasi Ilmiah, STKIP Taman Siswa Bima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37630/jpm.v13i3.1164

Abstract

Gejala gatal-gatal, ruam kulit, hidung tersumbat, bersin-bersin, mata merah, dan anafilaksis merupakan tanda dari alergi. Penanganan penyakit alergi dilakukan dengan pemberian terapi glukokortikoid, antileukotrien dan antihistamin H1. Sehingga tujuan dari penelitian ini adalah skrening bahan alam dengan metode Insilico. Alur cara kerja dimulai dengan mencari senyawa dari melati belanda, kemudian dipreparasi di chem axon, tahap selanjutnya adalah docking PLANT dan yang terakhir Visualisasi dengan menggunakan Discovery studio. Hasil dari peneltian ini adalah skordocking dari masing masing ligand yaitu: asquisqualic acid (-67,0166); arachidonic acid (-114,165); linoleic acid(-109,504); rutin ( -29,15); Quisqualic acid (-69,3609); Trigonelline (-65,1792); quinoline-4-carbonitrile (-76,9548); gallic acid (-70,2333); ellagic acid (-67,0591); flavogallonic acid (-30,9294); brevifolin carboxylic acid (-74,2838); quercetin(-82.544); β-sitosterol (-67,9037); lupeol (-30,033); linalool (-75,1704). Kesimpulannya yang memiliki energi terendah yang berpotensi sebagai inhibitor antihistamin adalah asam arachidonat.
Mekanisasi Peralatan Guna Meningkatkan Efektifitas dan Efisiensi Pencucian Sepatu di Jasa Laundry Sepatu Banjarbaru Nashrul Wathan; Mia Fitriana
Jurnal Pengabdian Masyarakat Panacea Vol 1, No 3 (2023): Jurnal Pengabdian Masyarakat Panacea
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jpmp.v1i3.10256

Abstract

UKM Shines shoes merupakan salah satu UKM yang bergerak di bidang jasa laundry sepatu di Kota Banjarbaru. Jasa laundry sepatu yang dijalankan oleh suatu UKM (Usaha Kecil Menengah) termasuk usaha yang cukup berkembang, seiring dengan kebutuhan masyarakat untuk merawat sepatunya. Proses pembersihan pada UKM ini masih secara manual dan menjadi kendala untuk UKM dikarenakan waktu pengerjaan yang tidak efisien. Kegiatan ini bertujuan untuk meningkatkan efektifitas dan efisiensi pencucian sepatu di usaha jasa laundry UKM Shine Shoes melalui mekanisasi peralatan pembersihan. Kegiatan diawali dengan persiapan kegiatan, penyerahan alat dan evaluasi atau pengamatan hasil. Setelah kegiatan pendampingan dan mekanisasi peralatan terdapat peningkatan efisiensi dan efektivitas pembersihan dibandingkan secara manual. Hal ini dapat meningkatkan daya jual produk jasa yang ditawarkan kepada konsumen sehingga diharapkan meningkatkan omzet mitra.Kata Kunci: Laundry, Sepatu, MekanisasiShines shoes is one of the service industries engaged in shoe laundry services in Banjarbaru City. Shoe laundry services run by small enterprises are a growing business, along with the need for people to take care of their shoes. The cleaning process in this SME was still manual and becomes an obstacle for SMEs due to inefficient processing time. This activity aimed to increase the effectiveness and efficiency of shoe washing in the laundry service business of UKM Shine Shoes through mechanization of cleaning equipment. The activity begun with the preparation of activities, delivered of tools and evaluation or observation of results. After the mentoring and equipment mechanization activities, there was an increase in the efficiency and effectiveness of cleaning compared to manually. This can increase the marketability of service products offered to consumers so that it is expected to increase partner turnover.
Increasing the Productivity and Independence of Ex-People with Mental Disorders (ODGJ) Through Life Skills Based Empowerment: Peningkatan Produktivitas dan Kemandirian Ex-Orang Dengan Gangguan Jiwa (ODGJ) Melalui Pemberdayaan Berbasis Life Skill Noor Cahaya; Nashrul Wathan; Siti Kaidah
Dinamisia : Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 2 (2024): Dinamisia: Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Lancang Kuning

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31849/dinamisia.v8i2.11134

Abstract

People with mental disorders experience disturbances in thoughts, feelings, and behaviors that cause them to experience decreased productivity and personal autonomy. The program was aimed at increasing the productivity and personal autonomy of ex-ODGJ through life skills-based training in the form of making handicrafts. The target of the program were ex-ODGJs who were undergoing the rehabilitation process at the Rumah Singgah "Baiman" in Banjarmasin. The program was conducted in three stages, survey, implementation, and evaluation. Implementation was conducted in the form of training, which was carried out in 2 meetings. The total number of participants was 20, and they were divided into 4 groups. At the first meeting, we were given an introduction to how to operate a sewing machine and the practice of sewing independently. In the second meeting, participants were asked to independently produce hampers. The conclusion of this program was in the form of a positive impact on ex-ODGJ, which was assessed based on the independence parameter of 75% of participants being able to independently produce handicraft products according to the stages that have been taught; a 100% attendance rate, which describes the participants' motivation to participate in the activity; and based on the results of a qualitative assessment through interviews, information was obtained that participants felt happy and benefited from the program.
Aktivitas antioksidan dan kandungan flavonoid total ekstrak etanol batang bajakah kalalawit (Uncaria cordata (Lour) Merr.) asal Kecamatan Loksado Kalimantan Selatan Wathan, Nashrul; Safarina, Nor Rezky; Fitriana, Mia
Sasambo Journal of Pharmacy Vol. 5 No. 1 (2024): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v5i1.230

Abstract

Bajakah kalalawit (Uncaria cordata (Lour) Merr.) is widely used by Dayak Tribes, based on empirical evidence, and often used to treat diabetes and various diseases such as cancer. This research aimed to determine the total flavonoid content and antioxidant activity of the ethanolic extract of U. cordata stems. The sample used bajakah kalalawit from Loklahung village, Loksado District, South Hulu Sungai Regency, South Kalimantan Province. Flavonoid levels were determined using quercetin standards, 10% AlCl3 reagent, and 5% acetic acid, then measured at a wavelength of 416 nm, while the antioxidant activity using DPPH 0.4 mM in UV-Vis spectroscopy at a wavelength of 516 nm. The results obtained were a thick extract mass with a dark brown color and a distinctive aroma. The total flavonoid content of the ethanol extract of U. cordata stems was found to be 3.6 ± 0.086 % w/w equivalent quercetin and showed very strong antioxidant activity with an IC50 value of 9.159 ppm.
Edukasi Mengenai Tanda Gejala, Penyebab dan Pencegahan Kolesterol di Apotek Syifa Banjarbaru Utami, Gusti Ayu Puspagita Mega; Putri, Hermalia; Wathan, Nashrul; Yulita, Rini
Jurnal Pengabdian Masyarakat Panacea Vol 2, No 1 (2024): Jurnal Pengabdian Masyarakat Panacea
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jpmp.v2i1.11884

Abstract

Salah satu bentuk dari senyawa lemak berlilin yaitu kolesterol. Kolesterol sebagian besar dihasilkan dari makanan. Kolesterol dikategorikan tinggi apabila berada di nilai 200-239 mg/dL. Penyakit kolesterol dapat dialami pada pasien anak-anak dan dewasa. Oleh sebab itu, penting dilakukan promosi kesehatan mengenai pengenalan tanda gejala, penyebab dan pencegahan kolesterol. Tujuan kegiatan promosi kesehatan yaitu untuk meningkatkan pengetahuan masyarakat khususnya pasien yang sedang berobat di Apotek Syifa mengenai tanda gejala, penyebab, dan pencegahan penyakit kolesterol. Promosi kesehatan dilakukan pada hari Selasa, 16 Januari 2024 jam 17.00 WITA sampai selesai di Apotek Syifa Banjarbaru yang beralamat di Jalan Panglima Batur No.15 Komp. Citra Megah Raya, Banjarbaru. Target promosi kesehatan yaitu pasien anggota PT PLN (Persero) yang menunggu obat atau menunggu antrian berobat ke dokter. Peserta promosi kesehatan yaitu dewasa yang didominasi kategori geriatrik. Pasien yang menjadi peserta promosi kesehatan terdiri dari 15 orang dengan 5 orang laki-laki dan 10 orang perempuan. Metode yang digunakan pada promosi kesehatan melalui penyampaian materi secara langsung kepada pasien (face to face) dengan menggunakan instrumen media cetak (leaflet). Sasaran edukasi adalah pasien yang menunggu obat atau menunggu antrian konsultasi pada dokter. Hasil yang diperoleh yaitu nilai pretest peserta promkes dengan rata-rata sebesar 54,67%, serta nilai posttest peserta promkes dengan rata-rata sebesar 80%. Kesimpulan dari promosi kesehatan adalah terjadi peningkatan pengetahuan pasien sebesar 25,33%. Kegiatan promosi kesehatan yang dilakukan diharapkan dapat merubah perilaku pasien dalam mengobati dan mencegah terjadinya kolesterol. Kata Kunci: Kadar Lemak Darah, Obesitas, Pola Hidup Sehat, Promosi Kesehatan  Cholesterol is a waxy fatty compound. Cholesterol mostly produced from food. Cholesterol is categorized as high at 200-239 mg/dL. Cholesterol disease can be experienced in children and adult patients. Therefore, it is important to carry out health promotion regarding the recognition of signs, symptoms, causes and prevention of cholesterol. The aim of health promotion activities is to increase public knowledge, especially patients who are seeking treatment at the Syifa Pharmacy regarding the signs, symptoms, causes and prevention of cholesterol disease. Health promotion on Tuesday, January 16 2024 at 17.00 WITA until finished at the Syifa Banjarbaru Pharmacy which is located at Jalan Panglima Batur No.15 Komp. Citra Megah Raya, Banjarbaru. The target of health promotion is patients who are members of PT PLN (Persero) who are waiting for medicine from a doctor. Participants in this health promotion are dominated by the geriatric category. There were 15 patients who participated in health promotion, consisting of 5 men and 10 women. The method used in health promotion is through delivering material directly to patients (face to face) using printed media instruments (leaflets). The target of education is patients who are waiting for medicine or waiting in line for a consultation with a doctor. The results obtained were the pretest score of health program participants with an average of 54.67%, and the posttest score of health program participants with an average of 80%. The conclusion of health promotion is that there has been an increase in patient knowledge by 25.33%. It is hoped that the health promotion activities carried out can change patient behavior in treating and preventing cholesterol.
Co-Authors Akbar, Nabila Hadiah Akhmad Rezeki Firdaus Akhmad Rezeki Firdaus Amalia Khairunnisa Amalia Khairunnisa Andini Rezeki Ayu Riana Sari Azwari Bella Na Fhory Deni Setiawan Dina Fadhila Zahra Fadlilaturrahmah Fadlilaturrahmah, Fadlilaturrahmah Fery Ramadhan Fitriyanti, Fitriyanti Gunarso, Sri Gunawan Gunawan Gunawan Indrayanto Herningtyas Nautika Lingga Hilneser Simamora Hilya Aulia Jariyah Amilia Jehan Azizah Kunti Nastiti Laili, Izzatul Lenie Marlinae M. Ikhwan Rizki Mia Fitriana Muhamad Saif Roies Yasa Muhammad Ikhwan Rizki Nadia Rahmah Nisriyati Fiddina Nita Pujianti Noor Cahaya Noor Erma Sugijanto Nurul Mardiati Okta Muthia Sari Okta Sari, Okta Putra, Aditya Maulana Perdana Putri Sari Muliani Putri, Hermalia Rahmi Annisa Rina Rina Rizki Swastika Puri Rizkiyah, Noor Annisa Safarina, Nor Rezky Salsabila, Risma Zahra Salwa, Helmina Samsul Hadi Sari, Risa Purnama Sariah Sariah Sarwo, Laura Saufy Arishandi Saufy Arishandi Sindwi Rinanda Sari Siti Kaidah sunardi sunardi Syahriah Syahriah Utami, Gusti Ayu Puspagita Mega Viogenta, Pratika Witiyasti Imaningsih Yasmine Puspita Sari Yodi Fernanda Yuana Sukmawaty Yulita, Rini