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All Journal Jurnal Ilmiah Farmasi Pharmascience Berkala Kedokteran Dinamisia: Jurnal Pengabdian Kepada Masyarakat Journal of Midwifery and Nursing JURNAL PENDIDIKAN MIPA Jurnal Pengabdian Kepada Masyarakat (Mediteg) Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Borneo Journal Of Pharmascientech Sasambo Journal of Pharmacy Jurnal Pengabdian Ilung (Inovasi Lahan Basah Unggul) Makara Journal of Science Jurnal Pengabdian Masyarakat Panacea Jurnal Sains dan Kesehatan
Nashrul Wathan
Lambung Mangkurat University
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Aktivitas Antioksidan serta Uji Flavonoid Total Ekstrak Etanol dan Fraksi Etil Asetat Batang Saluang Belum (Luvunga sarmentosa (Blume) Kurz.): Antioxidant Activity and Total Flavonoid Content of Ethanol Extracts and Ethil Acetate Fractions of Saluang Belum Stem (Luvunga sarmentosa (Blume) Kurz.) Putri Sari Muliani; Samsul Hadi; Nashrul Wathan
Jurnal Sains dan Kesehatan Vol. 6 No. 3 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i3.1761

Abstract

Saluang belum plant (L. sarmentosa (Blume) Kurz.) is a plant comes from Kalimantan. This plant L. sarmentosa is known to contain flavonoid compounds that have potential antioxidant activity. This study aimed to determine the total flavonoid content and antioxidant activity of the ethanol extract and the ethyl acetate fraction of stem saluang belum L. sarmentosa. Determination of total flavonoid content was determined using colorimetric method with standard quarcetin,10% AlCl3, 5% acetic acid. The antioxidant activity test was carried out using the DPPH method based on the IC50 value. The results showed that the total flavonoid content of saluang belum stems L. sarmentosa for ethanol extract was 3,249 ± 0.002 % w/w equivalent to quarcetin and for the ethyl acetate fraction of saluang belum stems L. sarmentosa namely 2,518 ± 0.0025% w/w quarcetine equivalent. The results of the antioxidant activity test of the ethanol extract and the ethyl acetate fraction of stem saluang belum L. sarmentosa have IC50 values ??of 80.80 ± 1.1313 and 81.73 ± 0.4917 ppm. Based on the IC50 value, the ethanol extract and the ethyl acetate fraction of stem saluang belum L. sarmentosa indicate that they have antioxidant activity which is included in the strong category. Keywords:          Luvunga sarmentosa (Blume.) Kurz, Extract, Fractions, Total Flavonoids, Antioxidant   Abstrak Tumbuhan saluang belum (L. sarmentosa (Blume) Kurz.) berasal dari Kalimantan. Tumbuhan ini diketahui mengandung senyawa flavonoid yang berpotensi memilki aktivitas antioksidan. Penelitian ini bertujuan untuk menetapkan kadar flavonoid total ekstrak etanol dan fraksi etil asetat batang saluang belum L. sarmentosa menggunakan metode spektrofotometri UV-Vis dan menentukan aktivitas antioksidan ekstrak etanol 96% dan fraksi etil asetat batang saluang belum L. sarmentosa yang dilihat berdasarkan nilai Inhibitor Concentration 50 (IC50). Penetapan kadar flavonoid total ditentukan menggunakan metode kolorimetri dengan standar kuarsetin dan reagen AlCl3 10% dan asam asetat 5%. Uji aktivitas antioksidan dilakukan dengan metode DPPH berdasarkan nilai IC50. Hasil penelitian menunjukkan kadar flavonoid total batang saluang belum L. sarmentosa untuk ekstrak etanol 96% yaitu 3,249 ± 0,002 % b/b ekivalen kuarsetin dan untuk fraksi etil asetat batang saluang belum L. sarmentosa yaitu 2,518 ± 0,0025 % b/b ekivalen kuarsetin. Hasil uji aktivitas antioksidan  ekstrak etanol 96% dan fraksi etil asetat batang saluang belum L. sarmentosa  mempunyai nilai IC50 berturut-turut yaitu 80,80 ± 1,1313 dan 81,73 ± 0,4917 ppm. Berdasarkan nilai IC50 yang didapat ekstrak etanol 96% dan fraksi etil asetat batang saluang belum L. sarmentosa menunjukkan bahwa memilki aktivitas antioksidan yang termasuk ke dalam kategori aktif. Kata Kunci:         Saluang belum (Luvunga sarmentosa (Blume) Kurz.), Ekstrak, Fraksi, Flavonoid Total, Antioksidan
Pengenalan Simplisia dan Pelatihan Pembuatan Teh Celup Telang dan Bawang Dayak Bagi Kader Puskesmas Mataraman Sari, Okta; Setiawan, Deni; Putra, Aditya Maulana Perdana; Wathan, Nashrul; Mardiati, Nurul; Lingga, Herningtyas Nautika; Akbar, Nabila Hadiah
Jurnal Pengabdian Kepada Masyarakat (MEDITEG) Vol. 9 No. 2 (2024): Jurnal Pengabdian Kepada Masyarakat (MEDITEG)
Publisher : Pusat Penelitian dan Pengabdian Kepada Masyarakat (P3M) Politeknik Negeri Tanah Laut (Politala)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34128/mediteg.v9i2.270

Abstract

Using traditional medicinal plants to create health products like herbal medicines and tea bags is one way to improve health. Telang (Clitoria ternatea) and Dayak Onion (Eleutherine bulbosa) are two types of plants that have great potential in the world of health, but their use has not been optimal. The purpose of this service is to improve the knowledge of Mataraman Health Centre cadres in the processing of herbal medicines and the utilisation of TOGA. At the Mataraman Health Center, community service has been conducted. The implementation of activities aimed at providing education on the introduction of herbal medicines using leaflets. Training is being conducted to process dry herbal medicines, utilize medicinal plants, and create tea bags. Evaluation of activities is carried out through pretests and posttests. A total of 10 cadres from Mataraman Health Centre participated in this activity. After receiving the education, the average level of knowledge among the participants increased to 84%. The use of herbal plants as herbal medicines can inspire the community to develop and preserve the potential of traditional medicinal plants. We hope that this activity will serve as a foundational step, providing cadres with valuable insights to develop herbal medicines.
Edukasi Pemanfaatan Mandiri TOGA kepada Kader Puskesmas Mataraman Putra, Aditya Maulana Perdana; Wathan, Nashrul; Lingga, Herningtyas Nautika; Setiawan, Deni; Sari, Okta Muthia; Mardiati, Nurul; Akbar, Nabila Hadiah; Sari, Risa Purnama; Rizkiyah, Noor Annisa; Salsabila, Risma Zahra; Salwa, Helmina
Jurnal Pengabdian Masyarakat Panacea Vol 2, No 3 (2024): Jurnal Pengabdian Masyarakat Panacea
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jpmp.v2i3.13245

Abstract

Pemanfaatan TOGA secara mandiri merupakan salah satu inisiatif untuk meningkatkan keterlibatan masyarakat dalam pengelolaan TOGA. Kader memiliki peran dalam mendukung masyarakat dalam pengelolaan kebun TOGA di masing-masing daerah. Tujuan dari pengabdian adalah peningkatan pengetahuan tentang pemanfaatan TOGA secara mandiri pada kader Puskesmas Mataraman setelah pemberian edukasi. Pada tanggal 6 Agustus 2024, tim pengabdian memilih ceramah sebagai metode yang diterapkan dalam edukasi. Kegiatan ditargetkan bagi kader desa wilayah kerja Puskesmas Mataraman. Evaluasi edukasi, proses keenam ini dilakukan dengan memberikan kuesioner pengetahuan TOGA sebelum edukasi materi dan sesudah edukasi materi. Sebanyak 10 orang berhadir dalam kegiatan. Berdasarkan hasil pengabdian diperoleh rerata pengetahuan peserta sebelum edukasi materi sebesar 78 % ± 16,61. Adapun pengetahuan peserta sesudah edukasi materi sebesar 92 % ± 13,27. Tim pengabdian telah menyerahkan TOGA sebanyak 14 jenis tanaman obat kepada Puskesmas Mataraman. Berdasarkan hasil , pada kader di wilayah kerja Puskesmas Mataraman terjadi peningkatan pengetahuan setelah diberikan edukasi tentang pemanfaatan TOGA mandiri.Kata Kunci: Apotek Hidup, Obat Herbal, Penggunaan Herbal, SosialisasiImplementing TOGA independently is a strategy to enhance community engagement in TOGA management. Cadres play a crucial role in assisting the community in the management of TOGA gardens in their respective areas. The objective of the service is to enhance the understanding and proficiency of the Mataraman Health Centre cadres in independently utilising TOGA, after the provision of education. On August 6, 2024, the educational team opted on lectures as the instructional approach. The activity was specifically aimed at village cadres who are part of the operating area of the Mataraman Health Centre. The evaluation of education involves administering a TOGA knowledge questionnaire. There were a total of 10 individuals who participated in the activity. The participants' average knowledge before the educational content was 78% ± 16.61 (standard deviation), as indicated by the service results. The participants' knowledge, after the educational material, reached a mean of 92% with a standard deviation of 13.27. The service team has delivered a total of 14 different varieties of medicinal plants. Ultimately, after delivering education on the independent use of TOGA, there was a discernible enhancement in the knowledge of the cadres within the working area of the Mataraman Health Centre.
Determination of specific and non-specific parameters of saluang belum (Luvunga sarmentosa (Blume) Kurz.) root extract and quantification of its total flavonoid content Dina Fadhila Zahra; M. Ikhwan Rizki; Wathan, Nashrul
Jurnal Ilmiah Farmasi Vol. 21 No. 1 (2025): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol21.iss1.art7

Abstract

Background: Saluang belum (Luvunga sarmentosa (Blume) Kurz.) is an endemic plant native to the Kalimantan region. The Dayak people traditionally consume a decoction of L. sarmentosa root to improve stamina. Previous research has confirmed that the roots of L. sarmentosa possess antioxidant properties.Objective: This study aims to determine the characterization values of both specific and nonspecific parameters of the ethanol extract from L. sarmentosa roots, as well as to assess the total flavonoid content.Method: The research samples were collected from Timpah Village, Central Kalimantan. The methods for standardization employed the general standard parameters for Indonesian Herbal Extracts and the Pharmacopoeia. Specific parameters include the characteristics of the extract, phytochemical screening, and thin-layer chromatography profiles, while nonspecific parameters consist of determining water content, total ash, acid-insoluble ash content, and heavy metal contaminants (Pb, Cd, and Hg). The total flavonoid content was determined using a colorimetric method with AlCl₃ and quercetin as the standard.Results: The extract was characterized as a thick, yellowish-brown substance with a strong, distinct odor and a bitter taste. It contains alkaloids, flavonoids, tannins, terpenoids, and steroids. The TLC profile revealed four distinct spots using a non-polar eluent and six spots with a polar eluent. The extract yield was 8.57%, with an average water content of 2.43±0.15%, total ash content of 1.50%, and acid-insoluble ash content of 1.00±0.87%. Heavy metal contamination levels were determined as follows: Pb < 0.001 mg/kg, Cd 0.446 mg/kg, and Hg 2.077 mg/kg. The total flavonoid content of the extract was quantified at 6.9147 ± 0.0083 mg QE/g.Conclusion: All specific and non-specific parameters of the extract meet the requirements except for the heavy metal contaminants of Hg and Cd, which are still within the threshold limits set by BPOM. Meanwhile, the total flavonoid content measured was 6.9147 ± 0.0083 mg QE/g.
Aktivitas Antibakteri Sediaan Microneedle Acne Patch Ekstrak Etanol Daun Belimbing Wuluh (Averrhoa bilimbi Linn) terhadap Staphylococcus epidermidis Fitriana, Mia; Sarwo, Laura; Wathan, Nashrul
BORNEO JOURNAL OF PHARMASCIENTECH Vol 9 No 1 (2025): Borneo Journal Of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59053/bjp.v9i1.658

Abstract

Acne is often accompanied by inflammation and triggers antibacterial activity such as S. Epidermidis. A. Bilimbi folium are known to inhibit the growth of S. Epidermidis. Microneedle (MN) is a preparation with small needles measuring 50-900 μm that can be applied to deliver active ingredients for acne treatment. The effect of concentration of A. Bilimbi MN acne patch leaf extract can cause changes in antibacterial activity. The purpose of this study was to determine the effect of the concentration of ethanol extract of A. Bilimbi folium on MN acne patch preparation on the inhibition of S. Epidermidis. The research was conducted by making 5 MN formulas with different extract concentrations and then testing the antibacterial activity with agar diffusion method. The negative control used was the formula without extracts while the positive control used chloramphenicol and acne patch preparation on the market. The results showed the clear zone of F1 (1%), F2 (5%), F3 (10%), F4 (15%), F5 (20%) of 1.86±0.485 mm; 3.15±0.556 mm; 5±0.526 mm; 8.25±0.687 mm; 9.43±0.809 mm, respectively. The conclusion of this study is that there was an effect of the concentration of ethanol extract of A. Bilimbi folium in the preparation of microneedle acne patches on the antibacterial activity of S. Epidermidis.
Co-Authors Akbar, Nabila Hadiah Akhmad Rezeki Firdaus Akhmad Rezeki Firdaus Amalia Khairunnisa Amalia Khairunnisa Andini Rezeki Ayu Riana Sari Azwari Bella Na Fhory Deni Setiawan Dina Fadhila Zahra Fadlilaturrahmah Fadlilaturrahmah, Fadlilaturrahmah Fery Ramadhan Fitriyanti, Fitriyanti Gunarso, Sri Gunawan Gunawan Gunawan Indrayanto Herningtyas Nautika Lingga Hilneser Simamora Hilya Aulia Jariyah Amilia Jehan Azizah Kunti Nastiti Laili, Izzatul Lenie Marlinae M. Ikhwan Rizki Mia Fitriana Muhamad Saif Roies Yasa Muhammad Ikhwan Rizki Nadia Rahmah Nisriyati Fiddina Nita Pujianti Noor Cahaya Noor Erma Sugijanto Nurul Mardiati Okta Muthia Sari Okta Sari, Okta Putra, Aditya Maulana Perdana Putri Sari Muliani Putri, Hermalia Rahmi Annisa Rina Rina Rizki Swastika Puri Rizkiyah, Noor Annisa Safarina, Nor Rezky Salsabila, Risma Zahra Salwa, Helmina Samsul Hadi Sari, Risa Purnama Sariah Sariah Sarwo, Laura Saufy Arishandi Saufy Arishandi Sindwi Rinanda Sari Siti Kaidah sunardi sunardi Syahriah Syahriah Utami, Gusti Ayu Puspagita Mega Viogenta, Pratika Witiyasti Imaningsih Yasmine Puspita Sari Yodi Fernanda Yuana Sukmawaty Yulita, Rini