Article Per Year (5 Year)
p-Index From 2021 - 2026
2.47
P-Index
This Author published in this journals
All Journal MEDIA MEDIKA INDONESIANA JURNAL GIZI INDONESIA Journal of Nutrition College Journal of Educational, Health and Community Psychology Journal of Biomedicine and Translational Research Sari Pediatri Universa Medicina Paediatrica Indonesiana Health Notions Jurnal Gizi Klinik Indonesia Indonesian Food Science and TechnologyJournal Jurnal Epidemiologi Kesehatan Komunitas Medica Hospitalia Jurnal Locus Penelitian dan Pengabdian Media Penelitian dan Pengembangan Kesehatan
Maria Mexitalia
Department Of Pediatrics, Faculty Of Medicine, Universitas Diponegoro
Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Education Electrical & Electronics Engineering Environmental Science Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Nursing Public Health

Published : 37 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search
Journal : MEDIA MEDIKA INDONESIANA

 1 
Skor Diskriminan Manifestasi Klinis dan Laboratorik sebagai Prediktor Syok pada Demam Berdarah Dengue Mohamad Supriatna; MMDEAH Hapsari; Maria Mexitalia; Yusrina Istanti
MEDIA MEDIKA INDONESIANA 2010:MMI VOLUME 44 ISSUE 3 YEAR 2010
Publisher : MEDIA MEDIKA INDONESIANA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (202.994 KB)

Abstract

Discriminant score of clinical and laboratory manifestations as a predictor of shock in dengue hemorrhagic fever Background: Case fatality rate of dengue shock syndrome (DSS) is still high. In Dr. Kariadi Hospital Semarang (RSDK) was 5.7 to 10.8% during 2000 to 2004. This is due to clinical course of dengue hemorrhagic fever (DHF) are unpredictable whether patients will develop to shock or not. We aimed to formulate discriminant score of clinical and laboratory manifestations that can be used as a predictor of shock in DHF.Methods: An observational analytic study was done. Consecutive sample were taken from DHF patients aged 3–14 years who were treated at RSDK in February 2001–March 2003. Diagnosis was established based on WHO 1997 criteria and serologic indirect-ELISA. Septic children were excluded. Clinical and laboratory manifestations were examined at admission or when diagnosed as DHF. Chi-square, Mann-Whitney, and discriminant analysis were done to formulate discriminant score.Results: There were 152 DHF patients enrolled, consist of 61 non-DSS and 91 DSS. Discriminant score formulation was obtained as: D=–1.103 + (0.013 x bleeding type) + (1.229 x vomiting) + (0.478 x abdominal pain) + (0.922 x hepatomegaly) – (0.039 x haemoglobin) + (0.014 x haematocryt) – (0.404 x albumin) – (0.046 x total protein) + (0.043 x pleural effusion index). Discriminant score mean for DSS is +0.739 and non-DSS –1.103 with cut-off point of –0.182. If the score <–0.182 patients become non-SSD and ≥–0.182 DSS. Conclusion: Discriminant score of clinical and laboratory manifestations can be used as a predictor of shock in DHF with prediction accuracy of 80.3%.ABSTRAKLatar belakang: Angka kematian sindrom syok dengue (SSD) masih tinggi. Di RSUP Dr. Kariadi (RSDK) Semarang 5,7–10,8% pada tahun 2000–2004. Hal ini disebabkan perjalanan klinis demam berdarah dengue (DBD) sulit diprediksi apakah penderita akan mengalami syok atau tidak. Tujuan penelitian adalah merumuskan skor diskriminan manifestasi klinis dan laboratoris yang dapat dijadikan sebagai prediktor syok pada DBD. Metoda: Dilakukan penelitian observasional analitik dengan sampel secara consecutive dari penderita DBD umur 3–14 tahun yang dirawat di RSDK pada Februari 2001–Maret 2003. Diagnosis ditegakkan berdasar kriteria WHO 1997 dan serologis indirect-ELISA. Anak dengan sepsis dieksklusi dari penelitian. Manifestasi klinis dan laboratoris diperiksa saat masuk rumah sakit atau saat diagnosis ditegakkan. Uji Chi-square, Mann-Whitney, dan analisis diskriminan dilakukan untuk merumuskan skor diskriminan.Hasil: Didapatkan 152 penderita DBD yang terdiri dari 61 non-SSD dan 91 SSD. Rumus skor diskriminan yang didapat sebagai berikut: D=–1,103 + (0,013 x jenis perdarahan) + (1,229 x muntah) + (0,478 x nyeri perut) + (0,922 x hepatomegali) – (0,039 x hemoglobin) + (0,014 x hematokrit) – (0,404 x albumin) – (0,046 x protein total) + (0,043 x indeks efusi pleura).Rerata skor diskriminan SSD +0,739 dan non-SSD –1,103 dengan cut off point –0,182. Bila skor <–0,182 penderita akan menjadi non-SSD dan ≥–0,182 akan menjadi SSD. Simpulan: Skor diskriminan manifestasi klinis dan laboratoris dapat dijadikan sebagai prediktor syok pada DBD dengan 80,3% ketepatan prediksi.
Respons Histopatologik Karsinoma Serviks Uteri Setelah Pemberian Kemoradiasi T Mirza Iskandar; Maria Mexitalia; Sarjadi Sarjadi; Edi Dharmana; Noor Pramono
MEDIA MEDIKA INDONESIANA 2011:MMI Volume 45 Issue 3 Year 2011
Publisher : MEDIA MEDIKA INDONESIANA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (99.404 KB)

Abstract

ABSTRACTFactors associated with histopathologic responses of cervical cancer after chemoradiation therapyIntroduction: Cervical carcinoma is the second most common women cancer in the world. A combined of surgical, radiation and chemotherapy is the main cervical carcinoma treatment. The histopathological response is one performance to assess the result of the treatment. The purpose of the study is to analyze the factors of cervical cancer which contributes to the histopathological response after chemoradiation treatment.Methods: The design of the study was a case control, done at Dr. Kariadi Hospital Semarang in 2008. Patients with biopsy-proven cervical carcinoma were entered into the study. The variables of risk factors included the stage of the cancer by FIGO staging, the type and differentiation of the tumour, the anemia and the history of the transfusion and the immunotherapy by BCG vaccine. The histopathological response was assessed after the chemoradiation treatment. Chi-square was used to analyze the risk factors and logistic regression was used for the multivariate analysis.Results: Between April-August 2008, 77 patients finished the chemoradiation treatment. The type of the cancer was squamous cell carcinoma (71.4%) and the stage was III B (81.8%). The staging, type and differentiation of the tumor, and the history of transfusion did not contributes to the histopathological response. After adjustment of other factors, the contribution of anemia to poor histopathological response were 6.25 times (95% CI 1.12-34.90; p=0.037) higher than good histopahological response.Conclusion: Anemia is the risk factor of poor histopathological response of cervical carcinoma after chemoradiation therapy.Keywords: Cervical carcinoma, chemoradiation, histopahological responseABSTRAKPendahuluan: Karsinoma serviks uteri (KSU) merupakan kanker kedua terbanyak pada wanita di seluruh dunia. Sampai saat ini terapi pilihan utama KSU adalah operasi, radiasi dan kemoterapi. Salah satu penilaian keberhasilan terapi adalah dengan respon histopatologik. Tujuan penelitian ini adalah menilai faktor-faktor yang berperan terhadap respons histopatologik setelah terapi kemoradiasi.Metode: Desain penelitian adalah kasus kontrol. Penelitian dilakukan di RSUP Dr. Kariadi Semarang. Kriteria inklusi adalah KSU yang telah menyelesaikan kemoradiasi. Faktor-faktor yang dinilai berperan terhadap respons histopatologi adalah tipe histologis dan diferensiasi tumor, stadium tumor berdasarkan FIGO, anemia dan riwayat transfusi serta pemberian imunoterapi dengan BCG. Analisis statistik menggunakan kai-kuadrat dan regresi logistik.Hasil: Selama periode April-Agustus 2008 terdapat 77 penderita yang menyelesaikan kemoradiasi. Sebagian besar penderita berada pada stadium IIIB (71,4%) dan mempunyai tipe histologi karsinoma sel skuamosa (81,8%). Stadium tumor, tipe histologi dan diferensiasi tumor, riwayat transfusi serta imunoterapi BCG tidak berperan pada respons histopatologik. Setelah memperhitungkan faktor perancu, risiko anemia terhadap respons histopatologi yang jelek adalah 6,25 kali (95% CI 1,12-34,90; p=0,037).Simpulan: Anemia merupakan faktor risiko terjadinya respon histopatologik yang jelek pada penderita karsinoma serviks uterisetelah mendapatkan terapi kemoradiasi.
Komposisi Tubuh dan Kesegaran Kardiovaskuler yang Diukur dengan Harvard Step Test dan 20m Shuttle Run Test pada Anak Obesitas Maria Mexitalia; MS Anam; Azusa Uemura; Taro Yamauchi
MEDIA MEDIKA INDONESIANA 2012:MMI VOLUME 46 ISSUE 1 YEAR 2012
Publisher : MEDIA MEDIKA INDONESIANA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (161.313 KB)

Abstract

Body composition and cardiovascular fitness measured by Harvard step test and 20m shuttle run test in obese childrenBackground: One of the impacts of obesity are physical and cardiovascular problems. Harvard step test and 20m shuttle run test can be used to measure cardiovascular fitness. Objective of this research is to determine the association between body composition with cardiovascular fitness in obese children measured by Harvard step test (HST) and 20m shuttle run test (SRT).Method: Cross sectional study was conducted to 31 students of Bernardus Elementary School Semarang in August 2010. Body composition (body mass index/BMI and fat percentage) was measured by Tanita BC545. Cardiovascular fitness was measured by HST and 20m SRT. During the step test Polar Vantage? Heart Rate (HR) monitor was attached to the subjects. Data were analyzed with Spearman correlation.Result: The average age was 10.7 (0.68) years. Only 17 children finished level III of Harvard test. The HR recovery never met the normal limit. There was no difference of physical fitness index (PFI) level I, II, and III (p=0.130) but the HR recovery decreased significantly (p=0.020). The mean of VO2max measured by 20m SRT was 20.5 (1.2) ml/kg/min, significantly lower compared with HST 24.2 (2.27) ml/kg/min. There were negative correlation between PFI and BMI (r=-0.381; p=0.034) and VO2max and BMI(r=-0.448; p=0.012).Conclusion: There are negative correlation between body mass index and cardiovascular fitness. However there are difference result of VO2max from Harvard step test comparing with 20m shuttle run test.Keywords: Harvard step test, 20m shuttle run test, physical fitness, obesityABSTRAKLatar belakang: Salah satu dampak obesitas adalah masalah fisik dan kardiovaskuler. Harvard step test (HST) dan 20m shuttle run test (SRT) merupakan tes yang digunakan untuk mengukur tingkat kesegaran kardiovaskuler. Tujuan penelitian adalah mengetahui hubungan komposisi tubuh dengan tingkat kesegaran kardiovaskuler pada anak obesitas menggunakan HST dan 20m SRT.Metode: Penelitian belah lintang dilakukan di SD Bernardus Semarang bulan Agustus 2010. Komposisi tubuh (indeks massa tubuh/ IMT) dan persentase lemak tubuh diukur dengan Tanita BC545. Dilakukan Harvard step test dan denyut jantung selama tes direkam menggunakan Polar Vantage Heart Rate (HR) monitor, serta dilakukan 20m SRT. Data dianalisis dengan uji korelasi Spearman.Hasil: Tiga puluh satu anak obesitas berumur 10,7(0,68) tahun mengikuti penelitian ini. Hanya 17 anak yang bisa menyelesaikan tes Harvard sampai tahap III. Didapatkan rerata HR saat istirahat lebih tinggi dibanding normal. Tidak didapatkan perbedaan physical fitness index (PFI) antara tes I, II, dan III (p=0,130) tetapi didapatkan penurunan HR recovery I, II, dan III yang bermakna (p=0,020). Rerata VO2max SRT 20,5(1,2) ml/kg/menit lebih rendah secara bermakna dibandingkan HST I yaitu 24,2(2,27) ml/kg/menit. Didapatkan hubungan terbalik antara PFI dengan IMT (r=-0,381, p=0,034) dan VO2max dengan IMT (r=-0,448, p=0,012).Simpulan: Didapatkan hubungan terbalik antara indeks massa tubuh dengan kesegaran kardiovaskuler pada anak obesitas, tetapi tidak didapatkan kesesuaian VO2max berdasarkan Harvard step test dan 20m shuttle run test.
Co-Authors Abdul Hakam Adhimah, Ayu Fauziyyah Adriyan Pramono Agustini Utari Ahmad Syauqy Alamsyah, Dedi Alamsyah, Dedi Ali Rosidi Alifiani Hikmah Putranti Ani Margawati Anindita Soetadji Anjani, Gemala Annastasia Ediati Any Setyarini, Any Avionita Latuihamallo Aya Yoshimura Ayu Diana Meilantika Azusa Uemura Bagoes Widjanarko Bambang Hariyana Bandawati, Bandawati Bob Kevin Pardede Darwati Darwati Diana Nur Afifah, Diana Nur Dwi Pudjonarko Edi Dharmana Ekowati, Liana Endrinikapoulos, Ariana Erna Mirani Etika Ratna Noer Faiza, Arif Farid Agung Rahmadi, Farid Agung Fitri Hartanto Hapsari, Widawati Hardhono Susanto Hariyana, Bambang Hendriani Sellina Henry Setyawan Susanto Henry Setyawan Susanto Herman Kristanto Hesti Kartika Sari Ihat Hatimah Ika Rara Rosita Irawan Saputra, Gatot Isfandiyar Fahmi Jaswir, Irwandi JC Susanto Julian Dewantiningrum Julian Dewantiningrum Jumianti Lestari Thamrin Kamilah Budhi Kamilah Budhi Rahardjani, Kamilah Budhi Kristiana Haryanti, Kristiana Kusuma Dewi, Anna Mailasari Latifah Rachmawati Leny Zabidi M. Supriatna M. Zen Rahfiludin Magdalena Sidhartani, Magdalena Maria Bramanwidyantari Maria Fatima Dete Dellu, Maria Fatima Dete Maria Martiani Martha Irene Kartasurya Mateus Sakundarno Mateus Sakundarno Mateus Sakundarno Adi, Mateus Sakundarno Miratul Haya MMDEAH Hapsari Mohamad Supriatna Mohammad Syarofil Anam Mohammad Syarofil Anam, Mohammad Syarofil Mohammad Zen Rahfiludin MS Anam Muflihatul Muniroh Muyassaroh Muyassaroh Neni Susilaningsih Ninung Kusumawati Ninung Rose Diana Kusumawati Noor Pramono Nurdiana Nurdiana Nurkukuh Nurkukuh Nurkukuh, Nurkukuh Nuryanto Nuryanto Nyoman Suci Widyastiti Panunggal, Damianus Galih Perdani, Putri Pratiwi, Juwita Pusaka, Semerdanta Resti, Nina Rina Pratiwi Robi Andoyo Romadhona, Suci Rudy- susanto S.A. Nugraheni Saputra, Epriyan Sarjadi Sarjadi Sellina, Hendriani Soejoenoes, Ariawan Soemedi Hadiyanto Suci Romadhona Sudrajat, Agus Suhartono, Suhartono Suharyo Hadisaputro Suharyo Hadisaputro Susilawati, Martvera SyarofilAnam, Moh. T Mirza Iskandar Taro Yamauchi Taro Yamauchi Taro Yamauchi Taro Yamauchi Thamrin, Jumianti Lestari Wijaya, I Made Ananta Wistiani Wistiani Yetty M Nency Yoshimura, Aya Yudo Murti Mupangati Yulia Wahyuni Yusrina Istanti