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Uji efek tonikum ekstrak daun sawo manila (Manilkara zapota) pada mencit putih jantan (Mus musculus) dengan metode ketahanan renang Fathnur Sani K; Yuliawati Yuliawati; Herlina Herlina; Reza Yolandini
Riset Informasi Kesehatan Vol 9 No 1 (2020): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (94.919 KB) | DOI: 10.30644/rik.v9i1.267

Abstract

ABSTRAK Penggunaan obat penambah stamina tubuh sangat dibutuhkan dalam kegiatan sehari-hari, pola aktifitas kerja masyarakat yang semakin meningkat membutuhkan tenaga yang lebih banyak sehingga dalam mengcukupinya perlu adanya suplemen penambah. Daun Sawo Manila merupakan salah satu tanaman yang sering digunakan untuk masyarakat sebagai penambah stamina. Pengujian ini bertujuan untuk mengetahui efek tonikum dari ekstrak daun sawo manila (Manilkara zapota). Metode yang digunakan pada penelitian ini adalah metode uji renang. Dimana dosis perlakuannya adalah kontrol positif (Kafein 0,52mg/20gram BB), control negative (Na CMC), Dosis I (6mg/20gramBB), Dosis II (12 mg/20 gramBB), dan Dosis III (18mg/20gramBB). Berdasarakan hasil Anova 1 arah menunjukkan adanya perbedaan yang bermakna pada tiap kelompok (p<0,05). Dimana berdasarkan uji lanjutan Duncan menunjukkan dosis terbaik adalah dosis III (18mg/20gramBB). Kemudian diikuti dosis II (12mg/20 gramBB) dan dosis I (6mg/20gramBB).
Pelatihan Pembuatan Sabun Lembaran Berbahan Aktif Kulit Buah Naga di Panti Asuhan Izzati Jannah Fathnur Sani K.; Yuliawati Yuliawati; Elisma Elisma; Syamsurizal Syamsurizal; Muhammad Syukri
Poltekita: Jurnal Pengabdian Masyarakat Vol. 4 No. 2 (2023): April-Juni
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (609.016 KB) | DOI: 10.33860/pjpm.v4i2.1802

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In recent years, the world has been shocked by the emergence of a disease caused by a virus, namely the corona virus or better known as COVID-19. The rapid spread of Covid-19 requires precautions to prevent transmission to break the chain of the COVID-19 pandemic and be able to face the new normal era. One of the preventive measures is to carry out the movement of washing hands with soap. Sheet soap is used as disposable hand soap and is perfect for use when traveling or doing activities outside the home. Currently, the community has started to carry out offline school and lecture activities. This activity aims to demand awareness to increase activities that are able to prevent the spread of Covid-19. So bringing antiseptic products, both in the form of liquids and sheet soap, is highly recommended to provide comfort in dealing with the new normal conditions after the Covid-19 pandemic. Activity method: This activity is planned to be carried out at the izzati jannah orphanage where the orphanage students have carried out learning activities offline. Activities are carried out following strict health protocols. The counseling activity was attended by 30 orphanage children. Based on the results of the post test, it was obtained a value of 92% of students being able to understand the training material provided. So that the results of the activity show that there is an increase in the knowledge of the orphans about processing dragon fruit peel powder into sheet soap that is easy to use and carry.
Uji Antibakteri Masker Serbuk Rimpang Kunyit (Curcuma domestica Val.) dan Tepung Beras terhadap Cutibacterium acnes Asima Widyawaty Sinurat; Yuliawati; Fathnur Sani K
Jurnal Kedokteran Meditek Vol 28 No 3 (2022): SEPTEMBER-DESEMBER
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v28i3.2358

Abstract

Tanaman kunyit (Curcuma domestica Val.) memiliki khasiat sebagai antibakteri karena adanya kandungan metabolit sekunder di dalamnya. Salah satu kandungan metabolit di dalam rimpang kunyit yang memiliki aktivitas sebagai antibakteri adalah curcumin dan minyak atsiri. Pembuatan sediaan topikal masker serbuk rimpang kunyit dan tepung beras memiliki keuntungan yaitu bahan-bahan yang digunakan adalah bahan alami sehingga aman digunakan. Tujuan penelitian ini untuk mengetahui formula masker serbuk terbaik yang beraktivitas sebagai antibakteri terhadap bakteri Cutibacterium acnes. Pengujian antibakteri terhadap C. acnes dilakukan menggunakan metode difusi cakram (5, 10, dan 15% g/g). Masker serbuk mustika ratu digunakan sebagai kontrol positif dan DMSO sebagai kontrol negatif. Evaluasi sediaan masker serbuk meliputi organoleptis, homogenitas, laju alir, sudut diam, kadar air, pengukuran pH dan cycling test. Hasil penelitian menunjukkan bahwa semua konsentrasi memiliki aktivitas antibakteri yaitu konsentrasi 5% sebesar 7,76 mm, 10% sebesar 10,63 mm, dan 15% sebesar 11,54 mm. Formula yang memiliki sifat fisik yang baik yaitu F2, diikuti F3 dan F1. Studi menyimpulkan bahwa formula F2 merupakan formula terbaik dari segi sifat fisik pada uji stabilitas selama penyimpanan. Formula F2 konsentrasi 15% memiliki aktivitas antibakteri yang paling baik dengan zona hambat sebesar 11,54 mm. 
PELATIHAN PEMBUATAN SNACK HERBAL SEBAGAI UPAYA PEMBERDAYAAN MASYARAKAT ANAK SUKU DALAM DI DESA PELEMPANG KABUPATEN MUARO JAMBI Fathnur Sani K; M.Rifqi Efendi; Puspa Dwi Pertiwi; Elisma Elisma; Yuliawati Yuliawati; Maimum Maimum; Indri Maharini
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 6 No. 2 (2023): MEDIC. Medical dedication
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/medicaldedication.v6i2.28152

Abstract

ABSTRACTJambi Province is one of the areas most inhabited by the Anak Dalam Tribe (SAD). Their estimated population in Jambi province alone is around 200,000 people. SAD life itself is often known as hunting and gathering to meet life's needs. Pelempang, Muaro Jambi Regency is one of the areas in Mestong village/sub-district, Muaro Jambi Regency, Jambi Province. Their distance which is quite far from the outside environment makes them live more by utilizing natural materials as a means of fulfilling their daily needs, ranging from food to medical needs. Herbal plants are a type of plant that is able to provide pharmacological effects on the body. In the last few years, we have been surprised by the emergence of a disease condition caused by a virus, namely the corona virus, better known as COVID-19. This condition requires us to always try to improve our health or body immunity to minimize the bad effects of this virus attack. So that many herbal products have emerged that are beneficial to the immune system, both in the form of beverage products and in the form of snacks so that what used to be known by the public about herbal medicines is a medicine that is not tasty and comfortable to consume, and has become a product that is delicious to eat and has benefits for the body's immunity. The distance of access means that education for the SAD community is also minimal. So it is important to provide additional knowledge to improve their quality of life and be able to blend in with the surrounding community. The solution offered in this activity is to provide knowledge and training about the importance of maintaining health and how to use medicinal plants to be given training in making herbal snacks which have many health benefits. This service activity will be carried out in Pelempang village, Maestong sub-district, Muaro Jambi district, Jambi province. This activity was carried out offline and was attended by 30 participants. The results of the activity show that there is additional knowledge for the SAD community in the process of processing herbal products that are delicious to enjoy.Keywords: snacks, SAD, Herbal, Palempang Village ABSTRAK Provinsi jambi merupakan salah satu wilayah yang paling banyak ditempati oleh Suku Anak Dalam (SAD). Perkiraan jumlah populasi mereka di provinsi jambi sendiri adalah sekitar 200.000 orang. Kehidupan SAD sendiri sering dikenal dengan berburu dan meramu guna memenuhi kebutuhan hidup. Pelempang, kabupaten muaro jambi merupakan salah satu daerah yang berada didesa/kelurahan Mestong Kabupaten Muaro Jambi, Provinsi Jambi. Jarak mereka yang cukup jauh dari lingkungan luar membuat mereka hidup lebih memanfaatkan bahan alam sebagai sarana pemenuhan kebutuhan hidup mulai dari makanan hingga untuk medis. Tanaman herbal merupakan jenis tanaman yang mampu memberikan efek farmakologis bagi tubuh. Beberapa tahun terakhir kita sempat dikejutkan dengan munculnya kondisi penyakit yang disebabkan oleh virus yaitu corona virus yang lebih dikenal dengan COVID-19. Kondisi ini menuntut kita untuk selalu berupaya meningkatkan kesehatan atau imunitas tubuh untuk meminimalisir efek buruk dari serangan virus tersebut. Sehingga telah banyak bermunculan produk-produk herbal yang bermanfaat bagi kekebalan tubuh baik itu berbentuk produk minuman maupun berbentuk snack sehingga yang dulunya masyarakat mengenal obat herbal merupakan obat yang tidak enak dan nyaman dikonsumsi menjadi produk yang nikmat untuk d makan dan memiliki manfaat bagi imunitas tubuh. Jauhnya akses membuat pendidikan bagi masyarakat SAD juga minim. Sehingga pentingnya memberi pengetahuan tambahan untuk memperbaiki kualitas hidup mereka dan dapat berbaur dengan masyarakat sekitar. Solusi yang ditawarkan pada kegiatan ini adalah Memberikan pengetahuan dan pelatihan tentang pentingnya menjaga kesehatan dan cara pemanfaatan tanaman berkhasiat obat untuk diberikan pelatihan pembuatan snack herbal yang memiliki banyak manfaat bagi kesehatan. Kegiatan pengabdian ini akan dilaksanakan di desa pelempang kelurahan maestong kabupaten muaro jambi provinsi jambi. Kegiatan ini dilakukan secara offline yang dihadiri sebanyak 30 orang peserta. Hasil kegiatan menunjukkan adanya tambahan pengetahuan bagi masyarakat SAD dalam proses pengolahan produk herbal yang enak untuk di nikmati. Kata kunci: snack, SAD, Herbal, Desa Palempang
FORMULASI, UJI EFEKTIVITAS DAN UJI HEDONIK MASKER GEL PEEL OFF KOMBINASI EKSTRAK RIMPANG KUNYIT (Curcuma longa L.) DAN MADU (Mel depuratum) SEBAGAI PENINGKAT ELASTISITAS KULIT: FORMULATIO, EFFECTIVITY TEST AND HEDONIC TEST OF THE PEEL OFF GEL MASK COMBINATION OF TURMERIC RHIZOME EXTRACT (Curcuma longa L.) AND HONEY (Mel depuratum) AS ENHANCER ELASTICITY OF SKIN Monic Sri Cahnia; Muhaimin; Yuliawati; Uce Lestari; Fathnur Sani K
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 7 No 2 (2022)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v7i2.328

Abstract

Salah satu upaya untuk mengembalikan kekencangan kulit adalah menggunakan sediaan kosmetik yang mengandung antioksidan. Kandungan yang terdapat dalam kunyit dan madu diketahui memiliki manfaat sebagai antioksidan. Salah satu sedian kosmetik yang dapat meningkatkan kekencangan kulit adalah sediaan masker wajah. Tujuan penelitian ini untuk mengetahui formula masker gel peel off ekstrak rimpang kunyit dengan kombinasi madu yang mempunyai sifat fisik yang baik dan untuk mengethaui efektivitasnya dalam mengencangkan kulit wajah. Penelitian ini menggunakan metode Rancangan Acak Lengkap. Sediaan masker gel peel off dibuat 3 formula dengan konsentrasi ekstrak kunyit dan madu yang berbeda yaitu F1 (1% : 4%), F2 (2% : 2%) dan F3 (4% : 1%). Tahapan prosedur dalam penelitian ini meliputi determinasi tanaman, penyedian sampel, pembuatan simplisia rimpang kunyit, pembuatan ekstrak rimpang kunyit, formulasi masker gel peel off, evaluasi sifat fisik, uji stabilitas, uji hedonik dan uji efektivitas sediaan dalam mengencangkan kulit. Hasil pengujian sifat fisik dan uji stabilitas menunjukkan bahwa sediaan masker ekstrak rimpang kunyit dengan kombinasi madu pada F1,F2 dan F3 menunjukkan hasil yang berada pada rentang yang sesuai dengan parameter dan stabil selama penyimpanan. Dari hasil uji hedonik, F1 lebih disukai panelis dibandingkan dengan formula lain, F1 efektif dalam meningkatkan kekencangan kulit wajah tiap minggu selama pemakaian empat minggu ditandai dengan peningkatan persentase kekencangan kulit setiap kali pemakaian.
UPAYA PENINGKATAN MINAT BACA MELALUI PERINTISAN RUMAH BACA “ABDI” DAN PENDAMPINGAN BELAJAR DARI MAHASISWA UNTUK DESA MENDALO INDAH Yesi Nursofia Nursofia; Emi Efrini Efriani; Anisya Persi Persi; Monic Sri Cahnia; Yuliawati Yuliawati
Abdimas Siliwangi Vol. 4 No. 2: Juli 2021
Publisher : IKIP SILIWANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22460/as.v4i2p%p.6697

Abstract

The pioneering of the ABDI reading house (Asri, Baca and Inspirasi) was based on the low interest in reading students' books. Mendalo Indah Village, which is a village close to Jambi University, does not yet have a reading house. In addition, the Covid-19 pandemic has overwhelmed parents of students to teach their children, especially with relatively low mastery of technology. ABDI Reading House, as a form of student and lecturer concern for the surrounding environment, is here to provide solutions to the problems of reading interest and the needs of parents for their children's learning assistance. This program is implemented by a community service team from the Pharmacy Student Association of the Faculty of Medicine and Health Sciences in collaboration with lecturers. The Village Head of Mendalo Indah provides a house to be used as a reading house and is supported by the provision of reading houses by funding from Jambi University through the Village Development and Empowerment Holistic Program (PHP2D). Learning assistance is carried out every day offline according to community demand by establishing health protocols and learning is carried out interactively with the play while learning method. This dedication has given birth to reading houses with various facilities and an increase in the number of visits to reading houses. The community feels very helped by the presence of the ABDI reading house in Mendalo Indah Village.
Uji Efek Tonikum Ekstrak Etanol Daun Pecut Kuda (Stachytarpheta jamaicensis L. Vahl) pada Mencit Putih Jantan (Mus musculus): The Tonicum Effect of Ethanolic Extract of Stachytarpheta jamaicensis Leaves in White Mice Male (Mus musculus) Yuliawati Yuliawati; Rofifah Dhia Savira; Diah Tri Utami
Jurnal Sains dan Kesehatan Vol. 4 No. 1 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i1.871

Abstract

Tonic is a substance that can increase the bodys defense system. The stimulant effect that is intertwined with the tonic effect is carried out by the central nervous system. Pecut kuda leaf and bases are useful as stimulants and tonics. This research aims to determine the tonicum effect of ethanolic extract pecut kuda leaf in mice. This was an experimental study with completely randomized group design, using male white mice and divided into five namely two control groups (K- given Na CMC 0,5% and K+ given 13 mg caffeine) and three treatment groups (ethanolic axtract of pecut kuda with a dose 50, 100 and 200 mg/kgBW) and each treatment group was repeated 5 times. The methods used were natatory exhaustion test, hanging test and sleep induction test for the parameters observed were the mice'defense on the surface of the water, the duration of the mice endurance on the hanging device and the time the mice fell asleep.The results of the observation data using Duncan's One Way ANNOVA test. The results showed that the pecut kuda leaf extract was effective against the tonic effect test at doses of 50, 100, 200 mg/kgBW. It can be said that pecut kuda leaf extract at a dose of 200 mg/kgBW has almost the same effect as K+ (13mg caffeine).
Efek Pemberian Gel Ekstrak Etanol Daun Ekor Naga (Rhaphidophora pinnata (L.f) Schott) Sebagai Antiinflamasi Metode Carrageenan-Induced Air Pouch: The Effect of Administering Ethanolic Extract Gel from Ekor Naga (Rhaphidophora pinnata (L.f) Schott) Leaves as an Anti-Inflammation Carrageenan-Induced Air Pouch Method Fathnur Sani K; Kristin Simamora; Havizur Rahman; Ave Olivia Rahman; Yuliawati Yuliawati
Jurnal Sains dan Kesehatan Vol. 5 No. 5 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i5.1707

Abstract

The ethanol extract ekor naga leaves (Rhaphidophora pinnata (L.f) Schott) has been studied as an anti-inflammatory agent. This study aims to formulate a topical preparation of ekor naga leavesextract gel so that it can be a futher step from previous research as a product development effort. The research method used is experimental design. The treatment group was divided into five groups: positive control (Hydrocortisone), Formula 0 (Gel Base), Formula 1 (10% Extract Concentration), Formula 2 (15% Extract Concentration), and Formula 3 (20% Extract Concentration). The test animals used in each treatment group were 5 animals. The data obtained were analyzed using one way ANOVA with a 95% confidence level. The results showed that the more extracts, the better the anti-inflammatory effect. However, based on preparation evaluation data in previous studies regarding gel formulations, it was concluded that formula 2 was the best formula with an effect that was statistically almost the same as formula 3 and had good gel stability in the formulation. Keywords: Ekor Naga Leaves, Gel, Inflammation, Air Pouch Abstrak Ekstrak etanol daun ekor naga  (Rhaphidophora pinnata (L.f) Schott) telah diteliti memiliki efek sebagai agen antiinflamasi. Penenlitian ini bertujuan untuk memformulasi sediaan topikal gel ekstrak daun ekor naga sehingga dapat menjadi menjadi langkah lanjut dari penelitian sebelumnya sebagai upaya pengembangan produk. Metode penelitian yang digunakan adalah experimental design. Kelompok perlakuan dibagi menjadi lima kelompok yaitu: Kontrol positif (Hidrokortisone), Formula 0 (Basis Gel), Formula 1 (Konsentrasi Ekstrak 10%), Formula 2 (Konsentrasi Ekstrak 15%), dan Formula 3 (Konsentrasi Ekstrak 20%). Hewan uji yang digunakan masing-masing kelompok perlakuan 5 ekor. Data yang didapat dianalisis menggunakan ANOVA satu arah dengan tingkat kepercayaan 95%. Hasil penelitian menunjukkan bahwa semakin banyak ekstrak maka semakin baik efek antiinflamasinya. Namun berdasarkan data evaluasi sediaan pada penelitian sebelumnya tentang formulasi gel maka disimpulkan bahwa formula 2 merupakan formula terbaik dengan efek yang secara statistic hampir sama dengan formula 3 serta memiliki stabilitas gel yang baik dalam formulasi. Kata Kunci: Daun Ekor Naga, Gel, Inflamasi, Air Pouch
PENGARUH EKSTRAK DAUN EKOR NAGA (Rhaphidophora pinnata (L.f) Schott) TERHADAP KADAR MALONDIALDEHID DARAH PADA TIKUS DIABETES YANG INDUKSI ALOKSAN Fathnur Sani K; Havizur Rahman; Yuliawati Yuliawati; Agung Giri Samudra
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.623

Abstract

Ekor Naga (Rhaphidophora pinnata (L.f) Schott) leaves is a traditional medicinal plant that contains secondary metabolites of alkaloids, flavonoids, saponins, and tannins, which have antioxidant effects. Uncontrolled diabetes mellitus will be one of the triggers for high free radicals in the body. This study aims to determine the effect of the effect of ekor naga leaves extract which has potentian as an antioxidant on malondialdehyde levels as a prooxidant marker in alloxan-induced diabetes mellitus rats. The reseaech method used a post test only control group design. The test animals used were 20 animals, each group of 5 test animals. Group 1: Positive Control (Glibenclamide 10 mg/Kg BW), Group 2: Negative Control (Na CMC 0,5%), Group 3: Ekor Naga Leaf Extract 250 mg/Kg BW, and Group 4: Ekor Naga Leaves Extract 500 mg/Kg BW. The data taken is the level of malondialdehyde in the blood. The results were analyzed using One-way ANOVA with a 95% confidence level. The results showed that the ethanolic extract of the ekor naga leaves had a role in reducing Malondialdehyde or lipid peroxide in the blood in diabetic rats where the best dose is 500 mg/Kg with malondialdehyde yield of 0,569 nmol/mL. Followed by a dose of 250 mg/Kg BW with malondialdehyde value of 2,144 nmol/mL.
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL 50% BIJI PINANG (Areca catechu) DENGAN METODE DPPH (2,2-diphenyl-1-picryhydrazyl) Humaryanto; Fathnur Sani K; Yuliawati Yuliawati; Ave Olivia Rahman; Muhaimin Muhaimin
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 9 No. 1 (2023): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v9i1.659

Abstract

Areca nut is a plant that contains secondary chemical metabolites of flavonoids, alkaloids, tannins, terpenoids, and steroids. Where content has activity as an antioxidant. The aim of this study were to determine the antioxidant activity of 50% ethanol extract of areca nut against DPPH free redicals based on the IC50 value. Extraction method using 50% ethanol with maceration method. The antioxidant activity test was made with 5 concentration series, namely 10 ppm, 50 ppm, 100 ppm, 150 ppm, and 200 ppm. The extract was tested for free radical scavenging against DPPH (2,2-diphenyl-1-picrylhydrazyl) with a wavelength of 517 nm using a UV-Vis spectrophotometer. The comparator used is Vitamin C. The results showed that the 50% ethanol extract of areca nut has a very strong category of antioxidant activity with an IC50 value of 27,565 ppm, while a positive control of Vitamin C has an IC50 value of 28,546 ppm. The conclusion obtained from the above results is that 50% ethanol extract has very strong antioxidant activity.