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All Journal HAYATI Journal of Biosciences Althea Medical Journal Journal of Mathematical and Fundamental Sciences Global Medical and Health Communication Universa Medicina Molecular and Cellular Biomedical Sciences (MCBS) Berkala Ilmiah Kedokteran Duta Wacana Jurnal Ilmu Kedokteran dan Kesehatan JPPM (Jurnal Pengabdian dan Pemberdayaan Masyarakat) Health and Medical Journal Medika Kartika : Jurnal Kedokteran dan Kesehatan Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia
Diana Krisanti Jasaputra
Department Of Pharmacology, Faculty Of Medicine, Universitas Kristen Maranatha, Bandung
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Dentistry Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary

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Effects of Metformin, Avocado Seed, and Diabetic Ingredients Infusion to Weight and Fasting Blood Glucose on Sucrose Diet Rats Jasaputra, Diana Krisanti; Wargasetia, Teresa Liliana; Elizabeth, Elizabeth
Global Medical & Health Communication (GMHC) Vol 7, No 1 (2019)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (881.279 KB) | DOI: 10.29313/gmhc.v7i1.2917

Abstract

Metformin, an oral hypoglycemic drug which has metabolic effects and weight loss after 6–9 months; however, after 18 months, these effects disappear. Oral hypoglycemic drugs with no effect on raising the weight are needed. The objective of the study is comparing the effects of metformin, avocado seed infusion (AS), and diabetic ingredients/DI (green chiretta, Java tea, and bitter grapes) in increasing weight and fasting blood glucose of rats with sucrose diet. The research was conduct at the Pharmacology Laboratory, Faculty of Medicine Universitas Kristen Maranatha in February–August 2017. The results showed that metformin within six weeks reduced weight (75.55%) compared to control (+) with a hypercaloric diet (114.36%). Metformin and hypercaloric diet in rats for 14 weeks showed a 125.66% increase in weight, higher than control (+) (114.36%), although not significant (p>0.05). Weight in rats with hypercaloric and AS diet for 14 weeks was 94.30% and 81.68% in DI was lower than control (+) (114.36%), but not significant (p>0.05). Fasting blood glucose (FBG) of dietary hypercaloric rats and metformin was 123.75 mg/dL, higher than control (+), which was 85.75 mg/dL (p<0.01), whereas FBG infusion of AS and DI during 14 weeks: 85.75 mg/dL, and 99.50 mg/dL, not significant to control (+) (p>0.05). In conclusions, metformin increased rats body weight even though not significantly and fasting blood glucose in rats fed a hypercaloric diet for 14 weeks, while avocado seed infusion and diabetec ingredients infusion did not. EFEK METFORMIN, INFUSI BIJI ALPUKAT, DAN INFUSI RAMUAN DIABETES TERHADAP BERAT BADAN DAN GLUKOSA DARAH PUASA PADA TIKUS DIET SUKROSAMetformin, obat hipoglikemik oral berefek metabolik dan menurunkan berat badan (BB) setelah 6–9 bulan, namun setelah 18 bulan efek ini hilang. Diperlukan obat hipoglikemik oral yang tidak berefek meningkatkan BB. Tujuan penelitian ini membandingkan efek metformin, infusi biji alpukat (BA), dan infusi ramuan diabetes/RD (sambiloto, kumis kucing, dan bratawali) dalam meningkatkan BB dan glukosa darah puasa pada tikus diet sukrosa. Penelitian dilaksanakan di Laboratorium Farmakologi, Fakultas Kedokteran Universitas Kristen Maranatha periode Februari–Agustus 2017. Hasil penelitian menunjukkan metformin dalam waktu 6 minggu mengurangi penambahan BB (75,55%) dibanding dengan kontrol (+) diet hiperkalori (114,36%). Pemberian metformin dan diet hiperkalori pada tikus selama 14 minggu menunjukkan kenaikan BB 125,66%, lebih tinggi dibanding dengan kontrol (+) (114,36%), walaupun tidak signifikan (p>0,05). Berat badan pada tikus dengan diet hiperkalori dan infusi BA selama 14 minggu adalah 94,30% dan  RD 81,68%, lebih rendah dibanding dengan kontrol (+) (114,36%), namun tidak signifikan (p>0,05). Glukosa darah puasa (GDP) tikus diet hiperkalori dan metformin adalah 123,75 mg/dL, lebih tinggi dibanding dengan kontrol (+) 85,75 mg/dL (p<0,01), sedangkan GDP infusi BA dan RD selama 14 minggu adalah 85,75 mg/dL dan 99,50 mg/dL, tidak signifikan terhadap GDP kontrol (+) (p>0,05). Simpulan, metformin meningkatkan berat badan tikus walau tidak signifikan dan meningkatkan glukosa darah puasa pada tikus diet hiperkalori selama 14 minggu, sedangkan infusi biji alpukat dan ramuan diabetes tidak.
The Effect of Curcuma and Garcinia Peel on Rat PPARα Gene Expression Induced by High-Fat Diet Jasaputra, Diana Krisanti; Yumilia, Hoo; Gunadi, Julia Windi; Lesmana, Ronny; Permadi, Andieni Faqhira
Global Medical & Health Communication (GMHC) Vol 11, No 3 (2023)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v11i3.10993

Abstract

High levels of fat in the blood are a risk factor for nonalcoholic steatohepatitis liver disease. Indonesian medicinal plants that can decrease blood fat levels are turmeric and mangosteen peel. One of the mechanisms of blood fat-lowering drugs is to increase the expression of the PPARα gene. The purpose of this study was to assess the effect of turmeric and mangosteen peel on the expression of the PPARα gene in the rat liver induced by a high-fat diet. This research was conducted at Maranatha Biomedical Research Laboratory in February–October 2021, using male Wistar rats that were divided into 5 groups (n=5): negative control groups (no treatment), positive control groups (high-fat diet), turmeric, mangosteen, and fenofibrate groups, that was given high-fat diet continued by ethanol extract of turmeric, ethanol extract of mangosteen peel, and fenofibrate. At the end of the study, the animals were terminated, and the liver was extracted for RNA extraction and semi-quantitative PCR. The results showed that there was an increase in PPARα gene expression in the turmeric group and fenofibrate group, which were significantly different from the positive control group that received a high-fat diet (p<0.05) and between the fenofibrate group compared to negative controls that received standard chow diet (p<0.05). In conclusion, turmeric and fenofibrate are suggested to increase the expression of the PPARα gene in the liver induced by a high-fat diet.
Vitamin D Levels and Their Correlation with Predisposing Factors and Estimated Fetal Weight in Third Trimester of Pregnancy: an Observational Study Indahwati, Dwiwahju Dian; Jasaputra, Diana Krisanti; Budiono, Arief; Gunadi, Julia Windi; Lesmana, Ronny; Kusmawan, Steven Zerin Putra
Global Medical & Health Communication (GMHC) Vol 12, No 1 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i1.11953

Abstract

Vitamin D has a broad impact on the human body, including affecting the bones and the immune system. Vitamin D deficiency in pregnant women is a risk factor in several circumstances, such as preeclampsia, gestational diabetes, premature birth, and low birth weight babies. This study aimed to determine the vitamin D levels and their relationship to predisposing factors and estimated fetal weight in the third trimester of pregnancy. Eighteen pregnant women in their third trimester of pregnancy who received antenatal care in the Obstetric Clinic of Immanuel Hospital Bandung from January to December 2022 were used as subjects of this study. The inclusion criteria are third-trimester pregnant women, healthy, while the exclusion criteria are currently taking drugs that have side effects in pregnancy or having pregnancy disorders. Blood was taken to measure vitamin D levels, fetal weight was estimated with obstetric ultrasound, and the subjects filled in questionnaires about predisposing factors. The results showed ten pregnant women (56%) had vitamin D deficiency below 20 ng/mL in their third-trimester pregnancy. We found non-significant relationships (p>0.05) between predisposing factors (daily consumption of vitamin D, sun exposure, maternal age), estimated fetal weight, and vitamin D levels. This study concludes that 56% of pregnant women in their third trimester of pregnancy have vitamin D deficiency with no significant relationship with its predisposing factors and estimated fetal weight.
Perbandingan Pemberian Krim Feniletil Resorsinol dan Krim Hidrokuinon 2% dalam Memperbaiki Derajat Pigmentasi Melasma Angeline, Stephanie; Jasaputra, Diana Krisanti; Ratnawati, Hana
Jurnal Ilmu Kedokteran dan Kesehatan Vol 11, No 9 (2024): Volume 11 Nomor 9
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v11i9.15755

Abstract

Melasma adalah kondisi hiperpigmentasi epidermis dan dermis yang ditandai oleh makula kecoklatan pada wajah, sering ditemukan pada wanita usia 30-70 tahun di negara tropis seperti Indonesia. Hidrokuinon 2% adalah regimen topikal efektif untuk melasma, namun penggunaan jangka panjang dan dosis tinggi dapat menyebabkan okronosis dan dermatitis kontak. Feniletil resorsinol, senyawa pencerah alami yang menghambat aktivitas enzim tirosinase, dianggap lebih aman. Penelitian ini bertujuan untuk membandingkan efektivitas krim feniletil resorsinol dan krim hidrokuinon 2% dalam menurunkan derajat pigmentasi melasma. Uji klinik double blind dilakukan pada wanita menopause dengan melasma wajah, dibagi menjadi dua kelompok (masing-masing 27 subjek): kelompok A (krim feniletil resorsinol) dan kelompok B (krim hidrokuinon 2%). Krim digunakan setiap malam, diikuti dengan sunscreen SPF 20 setiap pagi hingga siang. Derajat pigmentasi diukur menggunakan skin analyzer Tab A One sebelum dan setelah 30 hari. Hasil menunjukkan penurunan derajat pigmentasi yang signifikan pada kedua kelompok (p=0,000), dengan rerata skor pasca-perlakuan kelompok A (6,41) lebih rendah dibandingkan sebelum perlakuan (13,33), dan kelompok B dari 13,23 menjadi 7,37. Uji Mann-Whitney menunjukkan tidak ada perbedaan signifikan antara kedua kelompok (p=0,326). Simpulan: krim feniletil resorsinol dan hidrokuinon 2% sama-sama efektif menurunkan derajat pigmentasi melasma.
Efektivitas Krim Kombinasi Anti Akne (Retinyl Palmitate 0,2%, Potassium Azeloyl Diglycinate 3%) Dibandingkan Krim Tretinoin Untuk Terapi Akne Vulgaris Pada Pasien di Klinik “X” Kota Bandung Gabriella, Raissa; Jasaputra, Diana Krisanti; Ratnawati, Hana
Jurnal Ilmu Kedokteran dan Kesehatan Vol 11, No 12 (2024): Volume 11 Nomor 12
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v11i12.16201

Abstract

Akne vulgaris merupakan penyakit umum pada unit pilosebasea yang disebabkan oleh meningkatnya produksi sebum, hiperkeratinisasi folikel, kolonisasi bakteri dan inflamasi. Berbagai panduan tatalaksana akne vulgaris terbaru menganjurkan penggunaan obat-obatan untuk akne vulgaris dengan mekanisme kerja yang berbeda yang menargetkan aspek-aspek patogenesis akne vulgaris secara bersamaan. Tujuan penelitian ini adalah mengetahui efektivitas krim kombinasi anti akne (retinyl palmitate 0,2%, potassium azeloyl diglycinate 3%) dibandingkan krim tretinoin 0,025% untuk terapi akne vulgaris pada pasien akne vulgaris derajat ringan hingga sedang. Penelitian kuantitatif intervensional ini dilakukan pada 50 pasien pria berusia 18-30 tahun dengan akne vulgaris derajat ringan hingga sedang yang dibagi dengan tabel randomisasi menjadi dua kelompok (masing-masing 25 subjek) : kelompok 1 (krim kombinasi anti akne) dan kelompok 2 (krim tretinoin 0,025%). Pada kedua kelompok dilakukan pengukuran derajat akne vulgaris sebelum dan setelah perlakuan 28 hari. Hasil penelitian menunjukkan penurunan derajat akne vulgaris yang signifikan pada kedua kelompok, dengan rerata skor derajat akne vulgaris pasca perlakuan kelompok 1 (0,16) lebih rendah dibandingkan sebelum perlakuan (1,72) dan pada kelompok 2 dari 1,60 menjadi 0,20. Uji T tidak berpasangan menunjukkan tidak ada perbedaan signifikan antara kedua kelompok perlakuan. Krim kombinasi anti akne dan tretinoin 0,025% memiliki efektivitas yang setara dalam menurunkan derajat akne vulgaris.
EFFECT OF ORAL TRIPEPTIDE-COLLAGEN ON MICROCIRCULATION (NAIL FOLDS) AND SKIN WRINKLES Jasaputra, Diana Krisanti; Surjati, Hani; Fen Tih
Berkala Ilmiah Kedokteran Duta Wacana Vol. 9 No. 2 (2024): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v9i2.927

Abstract

Background: Accelerated aging is associated with increased exposure to reactive oxygen species (ROS), leading to lower collagen and elastin levels in the body. This reduction reduces microvascular activity, causing microcirculatory disorders and skin wrinkles. Administering collagen tripeptides can help improve the microcirculation system. Objective: This study aims to investigate the effects of collagen tripeptide on improving microcirculation, reducing skin wrinkles, and lowering excessive ROS toxicity. Method: The research method used is experimental with a pre-post study approach without using a control group and descriptive quantitative data analysis. We measured microcirculation using a microscope, quantified ROS levels with the QYM-DI microscope, and assessed nasolabial fold depth with an acupuncture needle. Results: The study results indicate that collagen tripeptide significantly improves microcirculation, reduces skin wrinkles, and decreases excessive ROS toxicity. The non-parametric Wilcoxon test results are as follows: (1) there is a significant difference before and after collagen tripeptide consumption in terms of microcirculation improvement (p = 0.000), reduction of skin wrinkles on the nasolabial folds (p = 0.008), and reduction of ROS (p = 0.000). This improves microcirculation, which in turn reduces skin wrinkles on the nasolabial folds. Conclusion: Consuming collagen tripeptide for three months can improve microcirculation, reduce skin wrinkles on the nasolabial folds, and reduces ROS.
Pengaruh Nutrisi Dalam Meningkatkan Kadar Brain-Derived Neurotrophic Factor Pada Pasien Depresi Indriany, Dini; Siringo Ringo, Nalaraty Wahyu; Sanjaya, Ardo; Jasaputra, Diana Krisanti; Gunadi, Julia Windi
Health and Medical Journal Vol 7, No 1 (2025): HEME January 2025
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v7i1.1638

Abstract

Brain-derived neurotrophic factor (BDNF) merupakan salah satu molekular neurotropin dalam sistem saraf yang berperan dalam modulasi dan perkembangan sinapsis serta sebagai regulator penting dalam proses transmisi di hipokampus, neokorteks, otak kecil, striatum, dan amigdala yang berpengaruh dalam proses neuroregenerasi, neuroprotektif, dan neurogenesis. Tingginya angka depresi pada sebagian besar usia dewasa menetapkan bahwa depresi menjadi salah satu perhatian penting dalam masalah kesehatan mental sehingga banyak penelitian meneliti tentang masalah ini pada manusia. Pada penelitian ini digunakan metode narrative review dengan cara mencari artikel dari search engine Pubmed dan Google Scholar dengan kata kunci “BDNF” dan “nutrition” dan “probiotic” dan “depression” dan “vitamin”. Kriteria inklusi berupa artikel penelitian 10 tahun terakhir, bahasa Inggris, full text dapat diakses. Pada narrative review ini, didapatkan lima artikel penelitian yang menguraikan tentang hubungan sintesis BDNF di hipokampus dan daerah lainnya dengan perbaikan gejala pada pasien depresi melalui pemberian jus jeruk murni dengan kandungan flavonoid, suplementasi probiotik, konsumsi minyak zaitun, suplementasi vitamin D dan magnesium, serta konsumsi vitamin C. Hasil telaah menunjukkan terdapat peningkatan kadar BDNF di hipokampus, serta peningkatan modulasi jaringan saraf, neuroplastisitas, neuromaturasi, dan pembentukan sinapsis pada uji coba otak hewan pengerat pada pemberian flavonoid, probiotik, minyak zaitun, suplemen vitamin D dan magnesium, serta vitamin C. Oleh karena itu, pemberian flavonoid,probiotik,  minyak zaitun, vitamin D dan magnesium, serta vitamin C dapat menurunkan tingkat dan gejala depresi dengan cara meningkatkan sintesis BDNF pada hipokampus dan daerah otak lainnya
The effect of saffron serum on collagen density, inflammatory gene expression, and autophagy in UVB-exposed Wistar rats Octavia, Chitra; Gunadi, Julia Windi; Adhika, Oeij Anindita; Ishak, Lani; Jasaputra, Diana Krisanti; Rosali, Alexandrina Everdine; Sanjaya, Ardo
Universa Medicina Vol. 43 No. 3 (2024)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2024.v43.329-339

Abstract

BackgroundSkin aging is a complex biological phenomenon influenced by intrinsic and extrinsic factors. Photoaging can be prevented by applying phytochemicals that have sun-protective properties. This study aimed to evaluate the effect of saffron serum to restore collagen density and autophagy processes and reduce inflammatory gene expression in UVB-exposed Wistar rats. MethodsAn experimental laboratory study was conducted involving 20 male Wistar rats that were divided into 4 groups: control, UVB, UVB + base serum, UVB + saffron serum exposed to UVB radiation for 5 weeks with a total dose of 3100 mJ/cm2. The skin was extracted then underwent Masson Trichrome staining and real-time PCR to obtain collagen density and gene expression. ResultsThe gene expression of MMP1, IL6, TNFá, LC3, and p62 was significantly increased in the UVB group compared to the control group. Topical administration of saffron serum significantly increased collagen density (p=0.001). Induction by UVB significantly increased LC3 (p=0.020) and p62 (p=0.030) gene expression, indicating an inhibition of autophagy. The saffron serum might modulate autophagy by increasing LC3, but not significant (p=0.495) and significantly decreasing p62 gene expression (p=0.001). As for MMP1, IL6, and TNFá, no significant decrease in gene expression was found in the UVB + saffron serum group compared to the UVB group. ConclusionSaffron serum increases collagen density and modulates autophagy in the skin of UVB-exposed Wistar rats. Inflammatory markers were increased after UVB induction, but no differences were found after saffron serum topical administration.
Peran Alfamangostin dalam Minyak Jagung dalam Memperbaiki Profil Lipid pada Tikus yang Diinduksi Pakan Tinggi Lemak Tjahjani, Susy; Jasaputra, Diana Krisanti; Permadi, Andieni Faqhira; Hidayat, Ester; Sitepu, Valerie Caroline; Radithya, Putu Audiva
Majalah Kedokteran Indonesia Vol 74 No 1 (2024): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.74.1-2024-856

Abstract

Introduction: Alphamangostin is a component of the mangosteen peel extract (Garcinia mangostana L) that has potential as a therapy for dyslipidemia. However, alphamangostin has low solubility, resulting in low bioavailability when administered orally. This study aims to investigate the potential of alphamangostin dissolved in corn oil on serum lipid profiles in vivo.Methods: The study was conducted on 24 Sprague Dawley strain Rattus norvegicus rats divided into 6 treatment groups (NC, HFD, CO, D1, D2, and Sim), with 4 rats each group randomly assigned. After a 1-week acclimatization period, each group received the following treatments: standard diet for 4 weeks (NC), high-fat diet + propylthiouracil (PTU) for 4 weeks (HFD), HFD + corn oil (CO), HFD + alphamangostin in corn oil at 7 mg/KgBW (D1), HFD + alphamangostin in corn oil at 35 mg/KgBW (D2), and HFD + simvastatin at 3.6 mg/KgBW (Sim). Treatments for CO, D1, D2, and Sim were administered for 2 weeks. Serum total cholesterol, HDL, LDL, and triglycerides were examined before and after treatment, and the differences were analyzed statistically.Results: The administration of alphamangostin at a dose of 7 mg/KgBW (D1) and corn oil (CO) significantly decreased LDL cholesterol levels (p less than 0.05), and alphamangostin at a dose of 35 mg/KgBW (D2) significantly decreased triglyceride levels (p less than 0.05). Meanwhile, there were decreases in total cholesterol levels and increases in HDL cholesterol levels in the alphamangostin and corn oil groups, but these changes were not statistically significant (p greater than 0.05).Conclusions: Alphamangostin can reduce LDL cholesterol and triglyceride levels in high-fat diet-induced rats.
Effects of dietary protein combined with high-intensity exercise in restoring skin health in male rats Gunadi, Julia Windi; Lesmana, Ronny; Kastella, Faysal; Tarawan, Vita Murniati; Goenawan, Hanna; Gunawan, Decky; Jasaputra, Diana Krisanti
Universa Medicina Vol. 44 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2025.v44.152-161

Abstract

Background Protein is essential for skin integrity, while exercise modulates cellular and molecular processes that regulate autophagy, mitochondrial biogenesis, and collagen synthesis. This study evaluates the combined effects of dietary protein restriction and varying exercise intensities on epidermal thickness, autophagy markers (LC3, p62), mitochondrial biogenesis (PGC1α), and collagen synthesis (Col1a1, Col3a1) in male Wistar rats.    Methods An experimental laboratory study was conducted involving 32 male Wistar rats. They were randomized into 8 groups: control, low protein, low intensity, group IV, moderate intensity, moderate intensity low protein, high intensity, and high intensity low protein. Low protein diet (5%) compared to the control (24%) was given for 60 days, while the exercise regimen was eight weeks of treadmill exercise (low/10 m per minute, moderate/20 m per minute, and high intensity/30 m per minute) for 30 minutes a day, five days a week. Epidermal thickness, LC3, p62, PGC1α, Col1a1, and Col3a1 mRNA expression were measured at the end of the study. One-way ANOVA/Kruskal-Wallis followed by Tukey HSD/Mann–Whitney test was used to analyze the data.   Results A low-protein diet significantly reduced epidermal thickness (p=0.048), increased LC3 (p=0.043) and p62 (p=0.011), indicating impaired skin regeneration and autophagy. However, exercise, especially at high intensities with low protein, mitigated this effect by increasing both LC3 (p=0.011) and PGC1α (p=0.011).   Conclusions These findings highlight the compensatory role of exercise in maintaining tissue integrity under protein-deprived conditions in male rats. High-intensity exercise potentially enhances autophagy and mitochondrial biogenesis.
Co-Authors Ahmad Faried Alya Mardhotillah Azizah Angeline, Stephanie Annisa Amalia Ardo Sanjaya Arief Budiono Dani Dani Decky Gunawan, Decky Dwi Davidson Rihibiha Dwi Davidson Rihibiha Elizabeth Yohanes Ermi Girsang Ervi Afifah Ervi Afifah Ervi Afifah Evan Christian Evan Christian, Evan Fanny Rahardja Felisia Hilianti Fen Tih Fidelia, Catrinne Gabriella, Raissa Gani, Irna Permanasari Ginting, Chrismis Novalinda Gunadi, Julia Windi Hadi, Harry Tribowo HANA RATNAWATI Hanna Goenawan Hanna Sari W. Kusuma Hanna Sari Widya Kusuma Hanna Sari Widya Kusuma Harry Murti Harry Murti Hidayat, Ester I Nyoman Ehrich Lister Indahwati, Dwiwahju Dian Indra Bachtiar Indra Bachtiar Indriany, Dini Ishak, Lani Kastella, Faysal Kusmawan, Steven Zerin Putra Larissa Larissa Mochammad Aris Widodo Mochammad Aris Widodo MUCHTAN SUJATNO Octavia, Chitra Oeij Anindita Adhika Pangestuti, Balqist Sriprobo Penny Setyawati Martioso Permadi, Andieni Faqhira Philips Onggowidjaja Pratono, Dono Radithya, Putu Audiva Rizal Rizal Rizal Rizal Ronny Lesmana Rosali, Alexandrina Everdine Siringo Ringo, Nalaraty Wahyu Sitepu, Valerie Caroline Subangkit, Mawar Surawijaya, Ade Kurnia Surjati, Hani Susy Tjahjani Sutiman Bambang Sumitro Syamsul Arifin Teresa Liliana Wargasetia The Fransiska Eltania Tumanggal N.S.S., Wulan Vita Murniati Tarawan Wahyu Widowati Wahyu Widowati Wahyu Widowati Wahyudianigsih, Roro Wijayanto, Karen Regina Yumilia, Hoo