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UJI AKTIVITAS IMUNOSTIMULATOR FRAKSI ETIL ASETAT EKSTRAK ETANOL KELOPAK BUNGA ROSELLA (Hibiscus sabdariffa L.) TERHADAP PROLIFERASI SEL LIMFOSIT MENCIT GALUR SWISS SECARA IN VITRO BESERTA IDENTIFIKASI KANDUNGAN SENYAWA KIMIANYA Ulfah, Maria; Nirmalasari, Nirmalasari; Sasmito, Ediati
e-Publikasi Ilmiah Fakultas Farmasi Unwahas Semarang Jurnal Ilmu Farmasi & Farmasi Klinik Vol.10 No.1 Juni 2013
Publisher : e-Publikasi Ilmiah Fakultas Farmasi Unwahas Semarang

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Abstract

ABSTRACTImmunostimulatory agent has an important role in the treatment of infectious disease caused bypathogen. Roselle calyx (Hibiscus sabdariffa  immune system. The aims of this research was to know immunostimulatory activity of ethyl acetate fraction ofethanolic extract of roselle calyx on lymphocyte cell proliferation swiss strain mice and to identified thechemical compounds of the fraction.Roselle calyx was ext racted by maceration method using ethanol 96% as a solvent. The ethanolicextract was partitioned gradually by n-hexan and ethyl acetate. Series of ethyl acetate fraction were made toconcentration 10, 20, 50, 100, 200, 400 μg/mL and positive control PHA 10 μg/mL for tested to lymphocyte cellculture. Immunostimulatory act ivity test was done according to MTTAssay  Key words : roselle calyx, ethyl acetate fraction, MTTAssay , immunostimulatorymethod. Lymphocyte proliferat ion activity was analyzed statistically to the value of Optical Density (OD) result of the Enzyme LinkedImmunosorbent Assay (ELISA) reader using Kruskal Wallis Test continued by Mann Whitney Test (p<0,05).Identificat ion of the contents phenolic compounds and flavonoids performed by Thin Layer Chromatography(TLC).The result of the research showed that ethyl acetate fraction had lymphocyte cell proliferation activity atthe concentration of 50, 100, 200, and 400 μg/mL. The ethyl acetate fraction of roselle calyx contained phenoliccompounds and flavonoids.L.) used by community as a health drink to enhance body’s
STRATEGI BRANDING PADA UMKM KELURAHAN RUNGKUT KIDUL KOTA SURABAYA Nirmalasari, Nirmalasari; Anwar, Muhadjir
KARYA: Jurnal Pengabdian Kepada Masyarakat Vol 3 No 3 (2023): KARYA: Jurnal Pengabdian Kepada Masyarakat
Publisher : FKIP Universitas Samawa

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Abstract

Strategi branding yang kuat memiliki peran penting dalam membedakan UMKM dari pesaing, membangun citra merek yang positif, dan meningkatkan kesadaran merek di kalangan pelanggan potensial. Namun, banyak UMKM di Kelurahan Rungkut Kidul masih menghadapi tantangan dalam mengembangkan strategi branding yang efektif. Metode penelitian ini melibatkan survei lapangan, wawancara dengan pemilik UMKM, dan analisis konten branding yang ada. Hasil penelitian menunjukkan bahwa UMKM di Kelurahan Rungkut Kidul menghadapi tantangan dalam pengembangan branding mereka, termasuk keterbatasan sumber daya dan pemahaman terbatas tentang konsep branding. Beberapa UMKM telah menerapkan strategi branding yang efektif, yang melibatkan penentuan identitas merek yang kuat, foto produk yang menarik, serta pemilihan elemen-elemen visual yang khas, seperti logo dan warna merek. Selain itu, strategi branding yang sukses juga mencakup penggunaan media sosial untuk mempromosikan produk atau layanan dan upaya meningkatkan kualitas produk.
Pengukuran Pengukuran Tinggi Pohon Menggunakan Klinometer Di Taman Margasatwa Ragunan Bagian Utara Nirmalasari, Nirmalasari; Sihab, Mutia Ayaar; Cheren, Aurel; Dinillah, Rafika; Aidah, Roza Sani; Suryanda, Ade; Azrai, Eka Putri
Jurnal Ilmiah Ecosystem Vol. 24 No. 1 (2024): Ecosystem Vol. 24 No 1, Januari - April Tahun 2024
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35965/eco.v24i1.3894

Abstract

Ketinggian pohon adalah faktor yang dapat mempengaruhi kualitas pohon dan memperkirakan berbagai parameter seperti biomassa, cadangan karbon, pertumbuhan pohon, dan sebagainya. Artikel ini bertujuan untuk mengetahui ukuran tinggi dari beberapa pohon di Ragunan menggunakan alat klinometer yang mana memiliki manfaat juga untuk mengetahui faktor-faktor yang mempengaruhi pertumbuhan pohon, termasuk iklim, ketersediaan air dan juga interaksi dengan spesies lain. Metodologi penelitian artikel ini menggunakan metode deskriptif kuantitatif. Hasil yang didapatkan adalah Ficus sp. Sebagai pohon paling tinggi, yaitu 18,05 meter dan pohon Syzygium aqueum yang terpendek dengan tinggi 3,3 meter yang dihitung menggunakan phytagoras. Kesimpulannya, semakin tinggi pohon menandakan bahwa lingkungan tersebut memiliki kondisi yang baik untuk tempat tumbuh vegetasi, sehingga kondisi tanah pada pohon Ficus sp. memiliki kondisi tanah yang lebih baik daripada kondisi tanah pada pohon Syzygium aqueum. The height of trees is a factor that can influence tree quality and estimate various parameters such as biomass, carbon reserves, tree growth, and so forth. This article aims to determine the height measurements of several trees in Ragunan using a clinometer, which also serves to identify factors affecting tree growth, including climate, water availability, and interactions with other species. The research methodology of this article employs a quantitative descriptive method. The results indicate that Ficus sp. is the tallest tree, measuring 18.05 meters, while Syzygium aqueum is the shortest at 3.3 meters, calculated using the Pythagorean theorem. In conclusion, taller trees signify that the environment provides favorable conditions for vegetation growth, indicating that the soil conditions for Ficus sp. are superior to those of Syzygium aqueum.
Hubungan antara usia, paritas dan riwayat kuretase dengan kejadian plasenta previa di Rumah Sakit Muhamamdiyah Palembang Tahun 2023 Nirmalasari, Nirmalasari; Chairuna, Chairuna; riski, merisa
JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan P-ISSN : 1979-3340 e-ISSN : 2685-7987 Vol 15 No 4 (2023): DESEMBER
Publisher : NHM PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36089/job.v15i4.1519

Abstract

Placenta previa is a condition in which the placenta implants the lower uterine segment so that it covers all or part of the os in the uterus or birth canal and makes it difficult for the baby to be born. In developed countries, the prevalence of placenta previa ranges from 0.26% to 2.00% of all pregnancies. While some experts claim that between 2.4 and 3.56% of all births in Indonesia experience placenta previa. The purpose of this study was to determine the relationship between age, parity and history of curettage simultaneously with the incidence of placenta previa at Palembang Muhammadiyah Hospital in 2023 . Type and Design Research is quantitative using an analytic survey method with an approachcross sectional. The population in this study were all pregnant women who were treated at the Muhammadyah Palembang Hospital in 2022, totaling 1,716. The sample used amounted to 95 respondents. The results of the univariate analysis obtained from 95 respondents, there were 10 respondents (10.5%) who had placenta previa and 85 respondents (89.5%) who did not. The results of the chi-square statistical test for the variable maternal age obtained ρ value = 0.000, parity variable ρ value = 0.012 and curettage history variable ρ value = 0.000 less than α = 0.05 indicating that there is a significant relationship between maternal age, parity and history of curettage with the incidence of placenta previa at the Palembang Muhammadiyah Hospital in 2023. Suggestions for the leadership of the Palembang Muhammadyah Hospital are that it is hoped that the results of this research can be used as a basis or reference for the hospital in making health programs for pregnant women, especially the problem of placenta previa.
Pengembangan Media Pembelajaran Kotak Kromosom (KOKRO) Pada Materi Kromosom Kelas XII Sekolah Menengah Atas Nirmalasari, Nirmalasari; Aidah, Roza Sani; Diputri, Rimba Liewa Dinta; Widianti, Serli; Suryanda, Ade; Pusparini, Fitria; Dewahrani, Yulilina Retno; Rini, Daniar Setyo
EDUKATIF : JURNAL ILMU PENDIDIKAN Vol 6, No 1 (2024)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/edukatif.v6i1.6145

Abstract

Kesulitan dalam memahami materi genetika seringkali muncul akibat sifat abstrak dan ketersediaan media pembelajaran yang kurang memadai. Penelitian ini bertujuan mengatasi permasalahan tersebut dengan fokus pada pengembangan media pembelajaran "Kotak Kromosom" (KOKRO) untuk materi kromosom. Metode Research & Development (R&D) dengan model 3D digunakan dalam penelitian ini. Pengembangan KOKRO melibatkan tahap define, design, dan development, dengan validasi konten dan media oleh ahli Pendidikan Biologi. Kotak Kromosom adalah perangkat pengajaran berbentuk kotak dari kardus, dilapisi kertas pembungkus, dan bagian dalamnya dilapisi kertas berwarna cerah yang berisi gambar-gambar tentang kromosom. Hasil dari kedua uji tersebut dapat disimpulkan bahwa secara umum, media pembelajaran KOKRO layak digunakan dengan sedikit revisi kecil untuk meningkatkan efektivitasnya.
Pengaruh Viskositas Dan Kadar Air Terhadap Breakdown Isolasi Minyak Transformator Shell Diala B Nirmalasari, Nirmalasari; Ariwinoto, Diki; Kamali Amali, Lanto M; Tolago, Ade Irawaty
Jurnal Electrichsan Vol. 11 No. 2 (2022): November 2022
Publisher : Program Studi Teknik Elektro Universitas Ichsan Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37195/electrichsan.v11i2.286

Abstract

Faktor yang mempengaruhi menurunnya mutu dalam ketersediaan pelayanan energi listrik adalah ganguan terhadap minyak transformator, hal ini bisa disebabkan berbagai faktor diantaranya berupa adanya kontaminasi partikel-partikel serta uap air pada transformator. Penelitian ini bertujuan untuk mendeskripsikan pengaruh viskositas dan kadar air terhadap breakdown voltage minyak transformator Shell Diala B. Metode pengujian breakdown voltage berdasarkan standar IEC 156, elektroda setengah bola dengan jarak antara elektroda 2.5 mm. Hasil pengujian viskositas dan kadar air terhadap breakdown voltage minyak transformator Shell Diala B menunjukan viskositas pada minyak transformator dapat mempengaruhi breakdown voltage minyak transformator, semakin kecil nilai viskositas yang terkandung dalam minyak transformator, maka breakdown voltage minyak transformator akan semakin besar. Demikian pula kadar air yang ada didalam minyak transformator, semakin banyak kadar air yang terkandung didalam minyak transformator maka breakdown voltage yang terjadi pada minyak transformator akan semakin cepat (buruk). The factors that affect the quality in the availability of electrical energy services are disturbances to transformer oil, this can be caused by various factors such as contamination of particles and moisture in the transformer. This study aims to describe the effect of viscosity and water content on the breakdown voltage of Shell Diala B transformer oil. The breakdown voltage test method is based on the IEC 156 standard, hemispherical electrodes with a distance of 2.5 mm between the electrodes. The results of testing the viscosity and water content of the breakdown voltage of Shell Diala B transformer oil show that the viscosity of transformer oil can affect the breakdown voltage of transformer oil, the smaller the viscosity value contained in transformer oil, the greater the breakdown voltage of transformer oil. Likewise, the water content in transformer oil, the more water content contained in transformer oil, the breakdown voltage that occurs in transformer oil will be faster (bad).
Penerapan Prinsip Citizen’s Charter Di Kantor Dinas Penanaman Modal Dan Pelayanan Terpadu Satu Pintu Kabupaten Gowa Nirmalasari, Nirmalasari; Setiawati, Budi; Burhanuddin, Burhanuddin
Kajian Ilmiah Mahasiswa Administrasi Publik (KIMAP) Vol 2, No 3 (2021): Juni 2021
Publisher : Universitas Muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26618/kimap.v2i3.3843

Abstract

The study aimed to find out how openness of service, responsiveness, and public complaints about service available at the Office of Investment and Integrated Services of One Door Gowa Regency. This study used descriptive method. The number of informants in this study was 6 people. The results of this study showed that the DPM PTSP of Gowa Regency had hot fully implemented the Citizen’s Charter Principle as Oliver and Drewry’s theory of service oppeness, service responsiveness, and service grievance, because there was no collaboration with independent oversight institutions and sign service Charters; no publication of the complete organizational structure with the names of authorized officials and publication of service fees manually and online; there was no publication of information on performance targets and performance achievements online; did not yet have regulations regarding guaranteeing equal rights for service recipients; there was no collaboration with an independent agency as a mediator between the DPM PTSP GowaRegeny with the service recipient if there was no agreement to resolve complaints.
The Influence of Work Motivation, Work Discipline, and Work Environment on the Performance of Employees in the Production Division of UD. Suwarlandono Art Nirmalasari, Nirmalasari; Santoso, Bowo
Majapahit Journal of Islamic Finance and Management Vol. 5 No. 1 (2025): Islamic Finance and Management
Publisher : Department of Sharia Economics Institut Pesantren KH. Abdul Chalim Mojokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31538/mjifm.v5i1.400

Abstract

The era of globalization demands companies to boost competitiveness by optimizing human resources. Employee performance is a key factor in achieving organizational goals, influenced by work motivation, work discipline, and work environment. This study aims to analyze the effect of work motivation, work discipline, and work environment on the performance of employees in the production department of UD. Suwarlandono Art. The research method uses a quantitative approach with Partial Least Squares (PLS) analysis. The population in this study was 50 employees in the production department of UD. Suwarlandono Art, which was also used as a sample with a saturated sampling technique. The results of the study indicate that work motivation has a positive and significant effect on employee performance, work discipline has a positive and significant effect on employee performance, and the work environment has a positive and significant effect on employee performance. High work motivation, good work discipline, and a conducive work environment can improve employee performance optimally.
EFEKTIFITAS PENGGUNAAN MEDIA YOUTOBE TERHADAP HASIL BELAJAR MATEMATIKA SMP NEGERI 2 PAREPARE Nirmalasari, Nirmalasari
Tautologi: Journal of Mathematics Education Vol. 2 No. 2 (2024): Tautologi September 2024
Publisher : Prodi Pendidikan Matematika Fakultas Keguruan dan Ilmu Pendidikan (FKIP) Universitas Muhammadiyah Parepare

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31850/tautologi.v2i2.3345

Abstract

This research aims to determine the effectiveness of using the YouTube application in mathematics learning for class VIII UPTD students at SMP Negeri 2 Parepare. This type of research is Pre-Experimental. The sample for this research was students of class VIII UPTD SMP Negeri 2 Parepare in the odd semester of the 2021/2022 academic year using a sampling technique, namely cluster random sampling. Data collection was carried out using research instruments in the form of test sheets, student activity observation sheets, teacher ability observation sheets to manage learning and student response questionnaire sheets. The results of the research show that learning using YouTube media is effective in mathematics learning for class VIII students at UPTD SMPN 2 Parepare. This is shown by descriptive analysis, namely (1) student learning completeness is included in the "High" category with an average score of 87,038 where classically 100% of students have completed it, (2) student activities are in accordance with learning using YouTube media The average percentage obtained was 60.42% or in the "Good" category, (3) the average score for teacher ability in managing learning was 4.14 and included in the "Good" category and (4) the students' response to learning mathematics using YouTube media was very positive with an average of 71.88%. Meanwhile, based on inferential analysis using the one sample t-test in the posttest, a significant value of p = 0.000 < α = 0.05 was obtained and the one sample t-test on the gain value obtained a significant value of p = 0.000 < α = 0.05 so it can be concluded that H_0 is rejected and H_1 accepted, which means that there is effectiveness in using YouTube media in mathematics learning for class VIII students at UPTD SMPN 2 Parepare
Pengaruh Halal Knowledge dan Religiusitas terhadap Niat Membeli Produk Kosmetik Halal dengan Sikap Konsumen sebagai Mediasi Nirmalasari, Nirmalasari; Sanurdi, Sanurdi
Mutawasith: Jurnal Hukum Islam Vol. 8 No. 1 (2025)
Publisher : Prodi Hukum Ekonomi Syariah (Muamalah)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47971/mjhi.v8i1.1256

Abstract

This study aims to analyze the influence of halal knowledge and religiosity on the purchase intention of halal cosmetic products, with consumer attitudes as a mediating variable. The research adopts a quantitative approach using the Partial Least Square (PLS) method to process data obtained from 150 respondents, consisting of students from the State Islamic University (UIN) Mataram in 2023. Respondents were selected based on the criteria of being halal cosmetic users, with data collected through both online and offline questionnaires. The results of the study indicate that halal knowledge has a positive and significant effect on purchase intention (t-statistic value of 3.786, p-value < 0.05). However, its effect on consumer attitudes is not significant (t-statistic value of 1.526, p-value > 0.05). On the other hand, religiosity is found to have a positive and significant influence on both consumer attitudes (t-statistic value of 2.331, p-value < 0.05) and purchase intention (t-statistic value of 3.334, p-value < 0.05). The study also reveals that consumer attitudes do not significantly mediate the influence of halal knowledge or religiosity on purchase intention.