Article Per Year (5 Year)
p-Index From 2021 - 2026
6.644
P-Index
This Author published in this journals
All Journal JURNAL FARMASI GALENIKA Majalah Farmasetika Jurnal Ilmiah Farmasi Farmasyifa Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Riset Farmasi Bandung Conference Series: Pharmacy Jurnal Farmasi Galenika
Lanny Mulqie
Farmasi, Fakultas Matematika Dan Ilmu Pengetahuan Alam, Universitas Islam Bandung
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 57 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 57 Documents
Search

 2   3   4   5   6 
Uji Aktivitas Antijamur Ekstrak Etanol Daun Dadap Serep (Erythrina subumbrans (Hassk.) Merr) terhadap Trichophyton mentagrophytes dan Malassezia furfur Revi Eluvia Zahra; Lanny Mulqie; Siti Hazar
Bandung Conference Series: Pharmacy Vol. 4 No. 2 (2024): Bandung Conference Series: Pharmacy
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsp.v4i2.15037

Abstract

Abstract. The efficacy of dadap serep (Erythrina subumbrans (Hassk.) Merr) leaves is shown by the presence of secondary metabolite compounds that are very potential so that they can be used as natural antifungals. The results of phytochemical screening of ethanol extracts of dadap serep leaves showed the presence of alkaloid compounds, flavonoids, saponins and tannins that have antimicrobial activity. The purpose of this study was to determine the antifungal activity of dadap leaf extract against Trichophyton mentagrophytes and Malassezia furfur. This study used agar diffusion method with variation of concentration of ethanol extract of dadap serep leaves 50%; 25%; 20%; 15%; 10% and 5%. Comparator used ketoconazole and DMSO solvent control. Antifungal activity test parameters are indicated by the presence of inhibition zone characterized by the presence of clear zone around the punctures. The diameter of the inhibition zone formed against the fungus Trichophyton mentagrophytes with a concentration variation of 50%; 25%; 20%; 15%; 10% and 5% was 5.50 mm; 5.37 mm; 5.33 mm; 3.81 mm; 2.47 mm; 1.94 mm. While the diameter of the inhibition zone formed against Malassezia furfur fungus was 5.68 mm; 4.45 mm; 4.01 mm; 3.91 mm; 2.89 mm; 1.77 mm. Abstrak. Khasiat daun dadap serep (Erythrina subumbrans (Hassk.) Merr) ditunjukan dengan adanya senyawa metabolit sekunder yang sangat potensial sehingga dapat digunakan sebagai antijamur alami. Hasil skrining fitokimia dari ekstrak etanol daun dadap serep menunjukkan adanya kandungan senyawa alkaloid, flavonoid, saponin, dan tanin yang memiliki aktivitas antimikroba. Tujuan penelitian ini untuk mengetahui aktivitas antijamur ekstrak daun dadap serep terhadap jamur Trichophyton mentagrophytes dan Malassezia furfur. Penelitian ini dengan metode difusi agar cara sumuran dengan variasi konsentrasi ekstrak etanol daun dadap serep 50%; 25%; 20%; 15%; 10% dan 5%. Pembanding yang digunakan ketokonazol dan kontrol pelarut DMSO. Parameter pengujian aktivitas antijamur ditunjukan dengan adanya zona hambat yang ditandai dengan adanya zona bening disekitar sumuran. Diameter zona hambat yang terbentuk terhadap jamur Trichophyton mentagrophytes dengan variasi kosentrasi 50%; 25%; 20%; 15%; 10% dan 5% sebesar 5,50 mm; 5,37 mm; 5,33 mm; 3,81 mm; 2,47 mm; 1,94 mm. Sedangkan diameter zona hambat yang terbentuk terhadap jamur Malassezia furfur sebesar 5,68 mm; 4,45 mm; 4,01 mm; 3,91 mm; 2,89 mm; 1,77 mm.
Pola Penggunaan Obat Pasien Gagal Ginjal Kronik dengan Komplikasi DM di RSUD Majalaya Periode September-Desember Tahun 2023 Pramudita Putri Azzahra; Fetri Lestari; Lanny Mulqie
Bandung Conference Series: Pharmacy Vol. 4 No. 2 (2024): Bandung Conference Series: Pharmacy
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsp.v4i2.15485

Abstract

Abstract. Chronic renal failure is a medical condition that requires appropriate drug treatment to control symptoms and slow disease progression. This study aims to analyze the pattern of drug use in patients with chronic renal failure at RSUD Majalaya, Bandung Regency, West Java, during the period September to December 2023. In this study, data were taken from the medical records of chronic renal failure patients undergoing treatment at Majalaya Hospital. The research method used was descriptive with a retrospective approach, in which secondary data were analyzed to identify the types of drugs used and the doses given. The results showed that the types of drugs given to patients were Keto G Supplements and the use of furosemide diuretics. Then the use of DM drugs in chronic renal failure patients given are insulin, gliquidon, glimepirid, gliclazid and metformin. The use of cardiovascular drugs in patients with chronic renal failure given are bisoprolol, clopidogrel, furosemide, spironolactone, simvastatin, candesartan, amlodipine, isosorbide dinitrate, acetylsalicylate, enalapril maleate, propanolol and lisinopril. Then the use of drugs for other comorbidities in patients with chronic renal failure given are lansoprazole, dexketoprofen trometamol, ursodeoxycholic acid, etoricoxib, diosmin hesperidin, erdostein, ciprofloxacin and allopurinol. Abstrak. Gagal ginjal kronik adalah kondisi medis yang memerlukan penanganan obat yang tepat untuk mengontrol gejala dan memperlambat perkembangan penyakit. Penelitian ini bertujuan untuk menganalisis pola penggunaan obat pada pasien gagal ginjal kronik di RSUD Majalaya, Kabupaten Bandung, Jawa Barat, selama periode September hingga Desember 2023. Dalam penelitian ini, data diambil dari rekam medis pasien gagal ginjal kronik yang menjalani perawatan di RSUD Majalaya. Metode penelitian yang digunakan adalah deskriptif dengan pendekatan retrospektif, di mana data sekunder dianalisis untuk mengidentifikasi jenis obat yang digunakan serta dosis yang diberikan. Hasil penelitian menunjukkan bahwa jenis obat yang diberikan pada pasien yaitu Suplemen Keto G dan penggunaan diuretik jenis furosemid. Kemudian penggunaan obat DM pada pasien gagal ginjal kronik yang diberikan yaitu insulin, gliquidon, glimepirid, gliklazid dan metformin. Penggunaan obat kardiovaskular pada pasien gagal ginjal kronik yang diberikan yaitu bisoprolol, clopidogrel, furosemid, spironolakton, simvastatin, candesartan, amlodipin, isosorbid dinitrat, asetilsalisilat, enalapril maleate, propanolol dan lisinopril. Lalu penggunaan obat untuk komorbid lain pada pasien gagal ginjal kronik yang diberikan yaitu lansoprazol, dexketoprofen trometamol, asam ursodeoksikolat, etoricoxib, diosmin hesperidin, erdostein, siprofloksasin dan allopurinol.
Formulasi dan Pengujian Efektivitas Antijamur Ekstrak Garcinia mangostana L. dari Sediaan Hidrogel terhadap Jamur Candida albicans dengan Basis Alginat Dialdehid Zarawanda Zihan Nabila; Arlina Prima Putri; Lanny Mulqie
Bandung Conference Series: Pharmacy Vol. 4 No. 2 (2024): Bandung Conference Series: Pharmacy
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsp.v4i2.15609

Abstract

Abstract. This study aims to explore hydrogel formulations using Garcinia mangostana L. extract with a dialdehyde alginate base and test its effectiveness as an antifungal agent against the Candida albicans fungus. The extraction method is carried out using a suitable solvent to extract the active compound from Garcinia mangostana L. Next, the hydrogel is made by combining the extract with a dialdehyde alginate base through an ionic gelation process. The hydrogel formulations were evaluated physically and chemically to ensure stability and compatibility of the raw materials. The antifungal activity test was carried out using the agar diffusion method to determine the zone of inhibition against Candida albicans. The results showed that the hydrogel with Garcinia mangostana L. extract showed strong antifungal activity against Candida albicans. This research shows the potential applicability of Garcinia mangostana L. extract in dialdehyde alginate-based hydrogel formulations as an antimicrobial agent, especially in the context of fighting Candida albicans fungal infections which is quite strong with an inhibitory power of 12.6 mm on a paper disc and 17.9 mm with a hole in concentration. 18%. The implications of this research can open new avenues in the development of antifungal products from natural ingredients for medical and pharmaceutical use. Abstrak. Penelitian ini bertujuan untuk mengeksplorasi formulasi hidrogel menggunakan ekstrak Garcinia mangostana L. dengan basis alginat dialdehid dan menguji efektivitasnya sebagai agen antijamur terhadap jamur Candida albicans. Metode ekstraksi dilakukan menggunakan pelarut yang sesuai untuk mengekstrak senyawa aktif dari Garcinia mangostana L. Selanjutnya, hidrogel dibuat dengan menggabungkan ekstrak tersebut dengan basis alginat dialdehid melalui proses gelasi ionik. Formulasi hidrogel dievaluasi secara fisik dan kimia untuk memastikan stabilitas dan kompatibilitas bahan baku. Uji aktivitas antijamur dilakukan menggunakan metode difusi agar untuk menentukan zona hambat terhadap Candida albicans. Hasil menunjukkan bahwa hidrogel dengan ekstrak Garcinia mangostana L. menunjukkan aktivitas antijamur yang kuat terhadap Candida albicans. Penelitian ini menunjukkan potensi aplikatif ekstrak Garcinia mangostana L. dalam formulasi hidrogel berbasis alginat dialdehid sebagai agen antimikroba, khususnya dalam konteks melawan infeksi jamur Candida albicans yang cukup kuat dengan daya hambat 12,6 mm pada cakram kertas dan 17,9 mm dengan sumuran pada konsentrasi 18%. Implikasi dari penelitian ini dapat membuka jalan baru dalam pengembangan produk antijamur dari bahan alam untuk penggunaan medis dan farmasi.
Penetapan Kadar Fenol Total dan Flavonoid Ekstrak Kulit Pisang 'Kepok' Mentah Devi Zulfitriyana, Devi Zulfitriyana; Yani Lukmayani; Lanny Mulqie
Jurnal Riset Farmasi Volume 4, No. 1, Juli 2024, Jurnal Riset Farmasi (JRF)
Publisher : UPT Publikasi Ilmiah Unisba

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jrf.v4i1.3759

Abstract

Abstact. One of the bananas produced in Indonesia is banana kepok (Musa acuminata × Musa balbisiana (ABB Group) 'Kepok'. It is known that kepok banana peel has potential as an antibacterial. Compounds that have antibacterial potential include flavonoids, tannins and saponins. Based on this background, this study aims to determine how much total phenol and flavonoid levels are owned by kepok banana peel. In determining total phenol and flavonoid levels using the Uv-Vis spectrophotometer method. The results showed that total phenol levels were 135.3 mgGAE/g and flavonoids were 88.8 mgQE/g in kepok banana peel extract. Abstrak. Salah satu pisang yang diproduksi di Indonesia yaitu pisang kepok (Musa acuminata × Musa balbisiana (ABB Group) ‘Kepok’. Diketahui kulit pisang kepok memiliki potensi sebagai antibakteri. Senyawa yang memiliki potensi sebagai antibakteri diantaranya flavonoid, tannin dan saponin. Berdasarakan latar berlakang tersebut penelitian ini bertujuan untuk mengetahui seberapa banyak kadar fenol total dan flavonoid yang dimiliki oleh kulit pisang kepok. Pada penentuan kadar fenol total dan flavonoid menggunakan metode spektrofotometer Uv-Vis. Hasil penelitian menunjukkan kadar fenol total terdapat 135,3 mgGAE/g dan flavonoid terdapat 88,8 mgQE/g pada ekstrak kulit pisang kepok.
UJI AKTIVITAS ANTIBAKTERI FRAKSI ETIL ASETAT DAUN SAMBILOTO (Andrographis paniculata (Burm.f) Wallich ex Nees) TERHADAP BAKTERI Bacillus subtilis ATCC 6633 Lanny Mulqie; Siti Hazar; Agytesa Ficri Septian
JURNAL FARMASI GALENIKA Vol 4 No 2 (2017): Jurnal Farmasi Galenika Volume 4 No. 2, 2017
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Telah dilakukan uji aktivitas antibakteri fraksi etil asetat daun sambiloto terhadap bakteri Bacillus subtilis ATCC 6633 melalui penentuan konsentrasi hambat minimum (KHM) dan nilai kesetaraan fraksi etil asetat terhadap antibiotika pembanding, serta kromatografi lapis tipis (KLT) Bioautografi. Fraksinasi dilakukan dengan cara ekstraksi cair-cair menggunakan pelarut n-heksan, etil asetat, dan air. Penentuan KHM dilakukan dengan metode difusi agar, kemudian ditentukan nilai kesetaraan fraksi etil asetat daun sambiloto terhadap antibiotika pembanding (tetrasiklin). Nilai KHM fraksi etil asetat daun sambiloto terhadap Bacillus subtilis ATCC 6633 sebesar 16%. Aktivitas 1 mg fraksi etil asetat daun sambiloto terhadap Bacillus subtilis ATCC 6633 setara dengan 4,457 × 10-5 mg tetrasiklin. Golongan senyawa fraksi etil asetat daun sambiloto yang diduga memiliki aktivitas antibakteri adalah monoterpen dan seskuiterpen.
Aktivitas Antioksidan dari Ekstrak Kulit Buah Manggis dengan Metode Sonikasi Elvina Legia Helisa; Lanny Mulqie; Arlina Prima Putri
Jurnal Riset Farmasi Volume 4, No. 2, Desember 2024, Jurnal Riset Farmasi (JRF)
Publisher : UPT Publikasi Ilmiah Unisba

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jrf.v4i2.4971

Abstract

Abstract. Mangosteen grows in tropical countries, such as Malaysia, Thailand, and Indonesia. Mangosteen (Garcinia mangostana L.) has widespread pharmacological potential especially in the utilization of its fruit rind. The fruit contains bioactive compounds, such as xanthones and anthocyanins, which are mainly extracted from the rind. In addition, mangosteen has high antioxidant properties in helping neutralize free radicals. This study aims to establish the IC50 value of mangosteen rind extracts extracted with aquadest and ethanol using sonication method and determine that ethanol or aquadest extracts of mangosteen rind are more effective in providing antioxidant activity based on DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The extraction process was carried out using 96% ethanol and aquadest sonicated for 45 minutes and 90 minutes. The results of antioxidant activity testing conducted by DPPH method showed that the IC50 value of sonication extraction in 96% ethanol solvent and aquadest were 10.28 ppm and 46.52 ppm respectively. This indicates that the antioxidant activity of mangosteen rind using sonication method with 96% ethanol solvent and aquadest can still be categorized as very strong. The low IC50 value of mangosteen fruit peel ethanol extract compared to the IC50 value of mangosteen fruit peel aquadest extract indicates that the ethanol extract of mangosteen fruit peel has higher antioxidant activity and is more effective in reducing free radicals.
Penapisan Fitokimia Ekstrak Etanol Daun Kirinyuh Hasil Metode Ekstraksi Refluks dan Maserasi Mujittaba Mumarli; Lanny Mulqie; Suwendar
Jurnal Riset Farmasi Volume 4, No. 2, Desember 2024, Jurnal Riset Farmasi (JRF)
Publisher : UPT Publikasi Ilmiah Unisba

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jrf.v4i2.4972

Abstract

Abstract. Kirinyuh (Chromolaena odorata L.) is also called weed, is a perennial shrub from the aster group with straight, brittle stems and many branches. Traditionally, kirinyuh leaves are used as a wound healing medicine, mouthwash for sore throats, cough suppressants, antimalarials, headaches, antidiarrheals, astringents, antispasmodics, antihypertensives, anti-inflammatory, diuretics, and have antiprotozoal effects. Kirinyuh leaves have an identity compound, namely the quercetin compound which is resistant to heat from flavonoid derivatives that can inhibit bacterial growth. This study aims to identify the content of compounds found in the simplex and ethanol extract of kirinyuh leaves and to determine the results of the comparison of the content of compounds found in the extracts from the reflux and maceration extraction methods. The results of phytochemical screening of simplex and ethanol extracts of kirinyuh leaves from the reflux and maceration extraction methods gave the same results indicating the presence of alkaloids, polyphenols, flavonoids, saponins, anthraquinones, tannins, and steroids.
Co-Authors Aghnia Nurzahra Aghnia Nurzahra Agytesa Ficri Septian Amelia Alfia Insani Andri Nopriansyah Annisa Ajeung Wulandari Annisa Dila Perwitasari Annisa Rahmawati Annisa Rahmawati Arlina Prima Putri Arlina Prima Putri Aulia Tazki Ayu Suci Dewi Bertha Rusdi Daifa Ermanda Mawali Davina Rustyasari Deden Miftah Fauzan Desi Anom Sari Devi Zulfitriyana, Devi Zulfitriyana Devina Aulia Fitri Diena Elisa Cahyani Dieni Mardliyani Dinda Hana Elvina Legia Helisa Essy Sari Adhani Fani Eka Martiza Fetri Lestari Fetri Lestari Fhirda Robani Hazar, Siti Imas Yumniati Iqlima Khairunnisa Tanjung Kamilia Ayu Khairunnisa Kusnandar Anggadireja Laila Afifah AB Lily Nurjihan Luzhny Azzahra Mochamad Tanto Kuswanto Muhammad Fakhrur Rajih Mujittaba Mumarli Mutiara Nur Afni Nabila Nur Azhari Nabila Nur Latifa Nabila Nur Latifa Neng Yani Nia Epawati Pramudita Putri Azzahra Ratu Choesrina Ratu Choesrina Ratu Choesrina Ratu Choesrina Ratu Choesrina Ratu Choesrnia Resti Fauziyah Revi Eluvia Zahra Risa Apriani Hilyah Rise Yantika Sabila Adzika Salma Sani Ega Priani Septian, Agytesa Ficri Siti Aisyah Putri Chaniago Siti Hazar Siti Hazar Siti Hazar Siti Hazar Siti Hazar Siti Umniyyah Nabilah Sofie Ayunia Rachmawati Sri Peni Fitrianingsih Suwendar Suwendar Suwendar Syahla Alpia Rachman Syarifah Hasanah Syifa Egidia Delani Tati Kurniati Tika Siti Fatimah Umi Yuniarni Umi Yuniarni vini nur alfaeni Wafda Shofia Widiasari Widiasari Yani Lukmayani Zakiyyah Nurrosyidah Zalfa Neysa Salsabila Zarawanda Zihan Nabila