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Effects of Fermented Red Rice Bran on Gut Microbiota Modulation and Colorectal Cancer Prevention in a DMBA-Induced Mouse Model Anasyua, Fairuz Khairunnisa; Cahya, Sella Nur; Hanifah, Azka Khansa; Kusuma, Rio Jati; Rahmawati, Dini; Widyaningsih, Wahyu
Journal of Food and Pharmaceutical Sciences Vol 13, No 3 (2025): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.20690

Abstract

Colorectal cancer prevention is closely linked to gut microbiota modulation, particularly by increasing lactic acid bacteria (LAB) and short-chain fatty acids (SCFA). This study investigates the effect of fermented red rice bran on colon microbiota improvement. Fermented bran was produced by mixing red rice bran with water and yeast, followed by an analysis of the proximate composition, dietary fiber, resistant starch, antioxidants, and phenols. A quasi-experimental study was conducted on 30 mice, assigned to normal, negative control, 10% bran, 20% bran, 10% fermented bran, and 20% fermented bran groups. Colorectal cancer was induced using DMBA (20 mg/kgBW) intraperitoneally four times over two weeks. Treatment groups received bran or fermented bran ad libitum for 14 days. Cecal analysis showed that 20% red rice bran and 10% fermented bran significantly increased SCFA levels (p < 0.05), suggesting improved microbiota function, but did not significantly alter pH or LAB counts. These findings highlight the potential of fermented red rice bran in modulating gut microbiota, though further studies are needed to elucidate its long-term effects and mechanisms in colorectal cancer prevention.
Wireless Photoplethysmography (PPG) Measurement with Pulse Wave Velocity (PWV) Method for Arterial Stiffness Evaluation Dewi, Ervin Masita; Rahmawati, Dini; Kirana, Nurista Wahyu
Jurnal Rekayasa Elektrika Vol 20, No 1 (2024)
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17529/jre.v20i1.33486

Abstract

Indications of symptoms of cardiovascular disease can be seen from the level of elasticity of the arteries. The Pulse Wave Velocity (PWV) method using PPG signal analysis is used to determine the level of arterial stiffness based on the time difference between pulse waves of Photoplethysmography (PPG) signal measurements. PWV measurements use a non-invasive technique using pulse sensors on the fingers and toes, the measurement data is sent wirelessly using the ESP-NOW protocol. Analysis of the measured PPG signal is used as an approach to calculating the PWV value. Realization and testing can be used to measure the pulse in BPM and classify the index of arterial stiffness using the PWV method. The results of testing on 15 test volunteers from 3 age groups showed the results of an arterial stiffness index with indications of normal, stiff and very stiff arteries. The PWV value for the 20 year old group was 4.30-6.77 cm/s, normal arterial conditions. The age group of 30-40 years has a PWV value ranging from 5.11-8.77 cm/s, normal arterial conditions. The age group of 50-60 years had PWV values in the range of 10.69-18.43 cm/s, stiff and very stiff arterial conditions. Increasing age linearly affects the increase in PWV value. An increased PWV value may indicate an increase in arterial stiffness.
Analisis Kemandirian Siswa Down Syndrome (Studi Kasus Di Knowledge Link Intercultural School Sentul Kabupaten Bogor) Setyari, Fadhilla Nova; Rahmawati, Dini; Maulia, Desi
Innovative: Journal Of Social Science Research Vol. 4 No. 2 (2024): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v4i2.9634

Abstract

Penelitian ini dilatar belakangi oleh siswa down syndrome di Knowledge Link Intercultural School dimana siwa tersebut belum terbentuk kemandiriannya mengenai aktivitas sehari-hari. Tujuan dari penelitian ini untuk menganalisis kemandirian siswa dan pembiasaan kemandirian pada aktivitas keseharian siswa down syndrome di Knowledge Link Intercultural School dan faktor-faktor yang mempengaruhinya. Penelitian ini kualitatif dengan pendekatan studi kasus dengan observasi dan wawancara. Hasil dalam penelitian ini kemandirian siswa down syndrome berkembang diiringi dengan pendampingan dan pembiasaan yang dilakukan setiap hari di sekolah serta dukungan dalam bentuk apresiasi. Knowledge Link Intercultural School terus melakukan komunikasi dengan orang tua mengenai bagaimana kemandiriannya dirumah. Masih ditemukan adanya hasil yang baik pada kemandirian siswa down syndrome ini. Dari yang sebelumnya takut, pemalu, bahkan agak dipaksa dalam melakukan aktivitas kemandirian, seiring berjalannya waktu dibersamai dengan pendampingan dan dukungan dari pihak sekolah maupun pihak keluarga yang sangat luar biasa siswa down syndrome sudah mampu dikatakan mandiri.
Effects of Fermented Red Rice Bran on Gut Microbiota Modulation and Colorectal Cancer Prevention in a DMBA-Induced Mouse Model Anasyua, Fairuz Khairunnisa; Cahya, Sella Nur; Hanifah, Azka Khansa; Kusuma, Rio Jati; Rahmawati, Dini; Widyaningsih, Wahyu
Journal of Food and Pharmaceutical Sciences Vol 13, No 3 (2025): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.20690

Abstract

Colorectal cancer prevention is closely linked to gut microbiota modulation, particularly by increasing lactic acid bacteria (LAB) and short-chain fatty acids (SCFA). This study investigates the effect of fermented red rice bran on colon microbiota improvement. Fermented bran was produced by mixing red rice bran with water and yeast, followed by an analysis of the proximate composition, dietary fiber, resistant starch, antioxidants, and phenols. A quasi-experimental study was conducted on 30 mice, assigned to normal, negative control, 10% bran, 20% bran, 10% fermented bran, and 20% fermented bran groups. Colorectal cancer was induced using DMBA (20 mg/kgBW) intraperitoneally four times over two weeks. Treatment groups received bran or fermented bran ad libitum for 14 days. Cecal analysis showed that 20% red rice bran and 10% fermented bran significantly increased SCFA levels (p < 0.05), suggesting improved microbiota function, but did not significantly alter pH or LAB counts. These findings highlight the potential of fermented red rice bran in modulating gut microbiota, though further studies are needed to elucidate its long-term effects and mechanisms in colorectal cancer prevention.
PENGARUH DISIPLIN DAN MOTIVASI KERJA TERHADAP KINERJA KARYAWAN PADA PT NUTECH INTEGRASI JAKARTA SELATAN Rahmawati, Dini; Indirasari, Indri
JURNAL ILMIAH EKONOMI, MANAJEMEN, BISNIS DAN AKUNTANSI Vol. 2 No. 6 (2025): November
Publisher : CV. KAMPUSA AKADEMIK PUBLISING

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61722/jemba.v2i6.1563

Abstract

The purpose of this study is to determine the influence of discipline and work motivation on employee performance at PT Nutech Integrasi Jakarta Selatan, both partially and simultaneously. This research employs a quantitative approach. The population consists of 150 employees of PT Nutech Integrasi Jakarta Selatan. The sampling technique used in this study is Slovin’s formula, resulting in a sample size of 110 employees from the same company. The results of the analysis show that discipline and work motivation have a significant effect on employee performance, as indicated by an adjusted R square value of 0.812, which means that 81.2% of employee performance is influenced by these two variables, while the remaining 18.8% is affected by other factors not examined in this study. Based on the t-test, the discipline variable has a partial effect on employee performance, as shown by tcount > ttable (20.899 > 1.982) with a significance value of 0.000 < 0.05. Likewise, the work motivation variable also shows a partial effect, with tcount > ttable (7.725 > 1.982) and a significance value of 0.000 < 0.05. Furthermore, the F-test results indicate that discipline and work motivation have a simultaneous influence on employee performance, proven by Fcount > Ftable (231.733 > 3.08) and a significance value of 0.000 < 0.05. Therefore, it can be concluded that both discipline and work motivation significantly and simultaneously affect employee performance at PT Nutech Integrasi Jakarta Selatan Keywords: Dicipline, Work Motivation, Employee Performance
EFEKTIVITAS PENGGUNAAN BUFFER ALTERNATIF PADA ISOLASI DNA BUAH KEBEMBEM (MANGIFERA ODORATA GRIFF.) DENGAN METODE KITCHEN PREPARATION Rahmawati, Dini; Maharani, Agnes Yuantin; Nurochim, Imam; Sani, Mayadita Dwi
BIOGENIC : Jurnal Ilmiah Biologi Vol 3 No 2 (2025): Jurnal BIOGENIC: Jurnal Ilmiah Biologi
Publisher : Program Studi Biologi UNARS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36841/biogenic.v3i2.6283

Abstract

Penelitian ini bertujuan untuk mengetahui efektivitas penggunaan buffer alternatif pada isolasi DNA dari buah kebembem (Mangifera odorata Griff.) dengan menggunakan metode kitchen preparation. Jenis buah ini diketahui merupakan hasil persilangan dari Mangifera indica dan Mangifera foetida. Namun karena rasanya yang cenderung asam dan daging buahnya memiliki serat yang kasar, kebembem kurang diminati. Kebembem dikonsumsi dalam bentuk rujak, selai, asinan dan perisa alami untuk minuman. Kebembem memiliki nilai jual yang rendah, sehingga tidak banyak yang melestarikan keberadaannya dan terindikasi akan mengalami kepunahan. Isolasi DNA buah kebembem dilakukan menggunakan teknik kitchen preparation yang merupakan teknik sederhana menggunakan alat dan bahan yang mudah ditemui di sekitar. Buah pisang juga diisolasi sebagai pembanding (kontrol). Hasil penelitian menunjukan DNA buah kebembem dan pisang dapat terekstraksi dan terisolasi dengan jelas. Perbedaan hasil ditunjukan pada sampel dengan perlakuan buffer yang berbeda. Pada buffer sabun pencuci piring DNA yang diisolasi tidak jenih dan pita DNA tidak terlihat jelas jika dibandingkan dengan buffer berupa larutan detergen cair. Hal ini terjadi karena perbedaan konsentrasi bahan aktif surfaktan, dimana sabun pencuci piring mengngandung konsentrasi surfaktan yang lebih rendah. Konsentrasi surfaktan menentukan kemampuan buffer dalam memecah dinding sel, semakin kuat surfaktan maka semakin mudah dinding sel dihancurkan.
Bentuk Code-mixing Bahasa Arab Santri dan Ustaz Pondok Pesantren Darussalam Parmeraan, Kabupaten Padang Lawas Utara: Pendekatan Sosiolinguistik Ritonga, Arip Rachman; Rahmawati, Dini
Mahira: Journal of Arabic Studies & Teaching Vol. 3 No. 3 (2025)
Publisher : Pendidikan Bahasa Arab Fakultas Ilmu Tarbiyah dan Keguruan UIN Sunan Kalijaga Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/mahira.2025.33.03

Abstract

The multilingual environment at Pondok Pesantren Darussalam Parmeraan, where santri and ustaz alternate among Arabic, Indonesian, and Batak Mandailing, creates a natural setting for code-mixing in daily communication. This study aims to identify the forms and directions of code-mixing, examine the motivations for its use, and analyze its sociolinguistic functions in both educational and social interactions. A descriptive qualitative approach was employed, with data collected through observation, semi-structured interviews, and documentation, and analyzed using the Miles and Huberman interactive model. The findings indicate that the dominant forms of code-mixing are insertion, alternation, and congruent lexicalization, occurring outwardly (between Arabic and non-Arabic languages) and inwardly (between Indonesian and Batak Mandailing). Code-mixing functions as a communicative strategy, strengthens group solidarity, and reinforces religious identity within the pesantren community. This study contributes to understanding multilingual communication in Islamic educational settings and provides new insights into tri-lingual code-mixing, a rarely examined phenomenon in Indonesian sociolinguistics.
Ensuring the safety of students in pesantren: A study on the ministry of religious affairs' role in handling violence cases Rahmawati, Dini; Rohman, Ahmad Fatkhur
Jurnal Anifa: Studi Gender dan Anak Vol 6 No 1 (2025): June 2025
Publisher : Pusat Studi Gender dan Anak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32505/anifa.v6i1.10429

Abstract

Cases of violence within pesantren (Islamic boarding schools) continue to occur. According to data from the Indonesian Teachers Union Federation (FSGI), 101 children were recorded as victims of sexual violence in schools between January and August 2024—all within educational institutions, across eight different cases. Of these, three cases occurred in boarding schools, while the other five took place in institutions under the supervision of the Ministry of Religious Affairs. This qualitative descriptive study, based on a literature review, aims to analyze two key policies: the Decree of the Director General of Islamic Education No. 1262 of 2024 concerning Technical Guidelines for Child-Friendly Care in Islamic Boarding Schools, and the Minister of Religious Affairs Regulation No. 73 of 2022 on the Prevention and Handling of Sexual Violence in Educational Institutions under the Ministry of Religious Affairs. Data sources include articles, journals, books, and other relevant literature on violence in pesantren environments. The findings reveal that, despite the issuance of these regulatory policies, cases of violence in pesantren persist. The study underscores the urgent need to strengthen and clarify evaluation and enforcement mechanisms at all institutional levels to effectively prevent and address such cases.
EFEKTIVITAS PEMBELAJARAN DEFERENSIASI DALAM MENGOPTIMALKAN HASIL BELAJAR SISWA Hasanah, Siti Nur; Rahmawati, Dini; Handayani, Arri
Jurnal Visi Ilmu Pendidikan Vol 18, No 1 (2026): Januari 2026
Publisher : Universitas Tanjungpura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/jvip.v18i1.88968

Abstract

In the world of education, the main challenge faced by teachers is the diversity of student characteristics in one class. Differentiated learning strategies offer significant potential to increase learning effectiveness for students at various levels. The aim of this research is to evaluate the effectiveness of differentiated learning so that students can achieve optimal learning outcomes. Identifying the advantages and effective implementation methods for implementing differentiated learning at various levels of education is the main focus of this research. This article was written using a qualitative approach to literature review, which includes critical analysis of relevant articles. Ten articles published within the last five years"”from 2020 to 2024"”are the subject of this literature review. The results of the literature review show that differentiated learning can significantly increase student engagement and motivation, as well as their learning outcomes. This research found that differentiated learning is very effective in improving student learning outcomes. Thus, teachers are expected to be able to adopt this strategy in daily learning practice to improve student learning outcomes at various levels.Keywords: differentiated instruction, literature review, student learning outcomes.
HUBUNGAN PARENTNING STYLE DAN TINGKAT PENGETAHUAN ORANG TUA TENTANG SEX EDUCATION PADA ANAK USIA DINI DENGAN PERILAKU PENCEGAHAN SEXUAL ABUSE DI TK NEGERI PEMBINA SUBANG Diana Putri, Dwi; Rahmawati, Dini
Ensiklopedia Research and Community Service Review Vol 5, No 2 (2026): Vol. 5 No. 2 Februari 2026
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33559/err.v6i1.3770

Abstract

Sexual abuse in early childhood continues to rise and has become a serious issue, including in Subang Regency. Lack of parental knowledge about sex education and inappropriate parenting styles are contributing factors that increase this risk. Objective: This study aims to analyze the relationship between parenting style and parents’ level of knowledge about sex education for early childhood with sexual abuse prevention behavior at TK Negeri Pembina Subang. Methods: A quantitative research design with a cross-sectional approach was used. A total of 88 parents were selected through purposive sampling. The instruments included the Parenting Styles and Dimensions Questionnaire (PSDQ), a sex education knowledge questionnaire, and a sexual abuse prevention behavior questionnaire. Data were analyzed using Spearman Rank correlation tests. Results: Most parents applied a democratic parenting style (59.1%), had good knowledge of sex education (60.0%), and demonstrated good sexual abuse prevention behavior (72.7%). The Spearman Rank test indicated a significant relationship between parenting style and sexual abuse prevention behavior (r = 0.411; p < 0.001), as well as between parental knowledge of sex education and prevention behavior (r = 0.363; p < 0.001). Conclusion:There is a significant relationship between parenting style and parental knowledge about sex education and sexual abuse prevention behavior among parents of early childhood students at TK Negeri Pembina Subang. These findings highlight the importance of educating parents on sex education and implementing supportive parenting styles that encourage openness and child protection.     Keywords: Parenting Style, Parental Knowledge, Sex Education, Preventive Behavior, Sexual Abuse