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Journal : Ina Kidney

The Role of Physical Activity in Improving QOL of Patients Undergoing Hemodialysis Ferdiana, Asihanti Rosita; Samsu, Nur
Indonesian Journal of Kidney and Hypertension Vol 1 No 1 (2024): Volume 1 No. 1, April 2024
Publisher : PERNEFRI (PERHIMPUNAN NEFROLOGI INDONESIA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32867/inakidney.v1i1.114

Abstract

Patients undergoing hemodialysis (HD) experience increased mortality rates and decreased physical activity, which has an impact on patients' low quality of life (QOL). Physical activity has positively affected cardiovascular function, strength, and overall health status. On the other hand, physical activity has not been proven to cause any health hazards in HD patients. However, physical activity has not become a routine practice for HD patients, and there are no clear guidelines for physical activity in HD patients. Due to the inherent condition, intradialytic aerobic exercise appears to be the most suitable physical activity method for HD patients. However, research is still needed to assess the effectiveness and safety of intradialytic exercise (IDE) for HD patients in the long term. Research results can be used as a reference in developing the most appropriate IDE guidelines for HD patients.
Determinants of Nutritional Status and Quality of Life in Hemodialysis Patients Samsu, Nur
Indonesian Journal of Kidney and Hypertension Vol 1 No 1 (2024): Volume 1 No. 1, April 2024
Publisher : PERNEFRI (PERHIMPUNAN NEFROLOGI INDONESIA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32867/inakidney.v1i1.124

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Observational Study on How the Frequency of Dialyzer Reuse Impacts Hemodialysis Effectiveness Wicaksono, Ramadi Satryo; Gunawan, Atma; Samsu, Nur; Rifai, Achmad
Indonesian Journal of Kidney and Hypertension Vol 1 No 3 (2024): Volume 1 No. 3, December 2024
Publisher : PERNEFRI (PERHIMPUNAN NEFROLOGI INDONESIA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32867/inakidney.v1i3.152

Abstract

Background: The increasing practice of dialyzer reuse in hemodialysis raises critical concerns regarding its impact on efficacy, infection risks, and essential metrics such as Urea Reduction Ratio (URR) and Kt/V values. Addressing these concerns is paramount to establishing safe and optimal reuse limits through comprehensive performance assessments. Objective: To evaluate the feasibility of dialyzer reuse by assessing Kt/V and URR measurements. Methods: A prospective cohort study was conducted at RSUD Dr. Saiful Anwar's Hemodialysis Unit from November 2021 to January 2022. Data collection employed a standardized pilot form designed to collate Kt/V and URR data from all participants. Statistical analyses included repeated measures ANOVA to detect temporal changes in average Kt/V and URR, alongside Spearman correlation analysis to explore variable relationships. Results: The study encompassed 15 participants, revealing a statistically significant decline in both Kt/V and URR values across each reuse group (p < 0.05). Specifically, each subsequent reuse of the dialyzer corresponded to a decrement of 0.0469 units in Kt/V and 1.003 units in URR. Notably, by the 7th reuse, hemodialysis adequacy remained satisfactory, achieving an average Kt/V of 1.61. Furthermore, the study indicated that even up to 11 reuses could achieve a Kt/V > 1.4. Similarly, the average URR value for the 7th reuse was 70.207%, with the potential to maintain URR > 65% even after up to 13 reuses. Conclusion: This study unequivocally affirms that hemodialysis adequacy remains satisfactory up to the 7th reuse of dialyzers, despite observed declines in Kt/V and URR values over successive reuses.
Pathogenesis of Immune-Mediated Glomerulonephritis Samsu, Nur
Indonesian Journal of Kidney and Hypertension Vol 1 No 3 (2024): Volume 1 No. 3, December 2024
Publisher : PERNEFRI (PERHIMPUNAN NEFROLOGI INDONESIA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32867/inakidney.v1i3.158

Abstract

Most forms of glomerulonephritis (GN) are characterized by a pathogenic immune response, which is mediated by the action of various immune system elements, both innate and adaptive. What is clear is that the immunopathogenesis of GN is very broad and complex. Deposits of immune complexes in the glomeruli activate complement and glomerular injury due to the involvement of circulating inflammatory cells and glomerular intrinsic cells, ultimately resulting in a wide variety of clinical manifestations, which depend in part on the location and immunopathology of the patient, including genetic and environmental factors, from asymptomatic to rapidly progressive GN. Most of the treatment strategies for GN are non-specific, consisting of corticosteroids and cytotoxic agents. Thus, an advanced understanding of GN immunopathogenesis may offer many opportunities for future therapeutic interventions on an individual basis. To further facilitate understanding of the pathogenesis of GN, the author also includes a graphical abstract.
Should All Patients with Nephrotic Syndrome Undergo a Renal Biopsy? Samsu, Nur
Indonesian Journal of Kidney and Hypertension Vol 1 No 3 (2024): Volume 1 No. 3, December 2024
Publisher : PERNEFRI (PERHIMPUNAN NEFROLOGI INDONESIA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32867/inakidney.v1i3.160

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Intradialytic Hypotension: Is Reducing Extracorporeal Blood Flow Rate an Appropriate Intervention? Samsu, Nur
Indonesian Journal of Kidney and Hypertension Vol 2 No 1 (2025): Volume 2 No. 1, April 2025
Publisher : PERNEFRI (PERHIMPUNAN NEFROLOGI INDONESIA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32867/inakidney.v2i1.185

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