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All Journal Hemera Zoa Media Veteriner Jurnal Veteriner Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Layanan Masyarakat (Journal of Public Service) Jurnal Pengabdian Masyarakat Medika
Dwi Kesuma Sari
Study Program Of Veterinary Medicine, Faculty Of Medicine, Hasanuddin University, Jl. Perintis Kemerdekaan Km. 10, Makassar, 90245, South Sulawesi, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Medicine & Pharmacology Public Health Social Sciences Veterinary Other

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Effect of administration of ajwa date extract on renal histopathological changes in meloxicam induced in rats Abdul Halim, Musdalifah; Arsyad, M Aryadi; Dwi Kesuma Sari; Sartini Natsir; Muhammad Husni Cangara; Yulia Yusrini Djabir
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 7, No 2, JULY 2023
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jrvi.v7i2.21785

Abstract

Objective: This study aimed to examine the nephroprotector effect of ajwa date extract on the kidneys of white rats induced by meloxicam. Methods: 25 male (Rattus norvegicus) rats weighing 200-300 g were divided into 5 groups (n = 5), namely group 1 healthy control without meloxicam and ajwa date extract, group 2 negative control with meloxicam 30mg/kgBB without ajwa dates, group 4 with ajwa date extract 150mg/kgBW and meloxicam 30mg/kgBW, and group 5 with ajwa date extract 300mg/kgBW and meloxicam 30mg/kgBW. The treatment was given for 14 days, on the 15th day a necropsy was performed to take kidney organs for microscopic evaluation or histipathological examination. Results: Meloxicam at a dose of 30mg/kgBW caused damage to the kidneys with observations of glomerular hemorrhage, tubular necrosis, hydropic degeneration and narrowing of the tubular lumen as well as narrowing of the capsular space with an average degree of damage reaching 75% while ajwa date extract doses of 150 and 300mg/kgBW has a nephroprotector effect against meloxicam induction. Conclusion: Ajwa date extract doses of 150 and 300mg/kgBW had a nephroprotector effect on meloxicam induction.
The Effect of Ajwa Date Fruit Extract (Phoenix Dactylifera L.) Against Liver Damage in White Rats (Rattus Norvegicus) Induced by Meloxicam Fatimah Mappanyompa; Arsyad, M Aryadi; Sari, Dwi Kesuma; Natsir, Sartini; Cangara, Muhammad Husni; Djabir, Yulia Yusrini
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 7, No 1, JANUARY 2023
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jrvi.v7i1.21788

Abstract

Abstract Objective: This study was aimed to investigate the protective effect of Ajwa date palm extract (Phoenix Dactylifera L.) against liver damage in white rats (Rattus norvegicus) induced by Meloxicam. Methods: The samples used in this study were twenty five male white rats divided into five groups with body weight 200 – 300gr, namely a healthy control group, negative control given Meloxicam 30mg/kgBB, treatment group 1 was given Ajwa date fruit extract 75mg/kgBW and Meloxicam 30mg/kgBW, treatment group 2 was given Ajwa date fruit extract 150mg/kgBW and Meloxicam 30mg/kgBW, and treatment group 3 was given Ajwa date fruit extract 300mg/kgBW and Meloxicam 30mg/BW for 14 days. On the 15th day, the rats were anesthetized for blood tests and euthanized for liver organ observation. Results: The result showed by giving Ajwa date palm extract with higher doses and Meloxicam 30mg/kgBW, resulted a decrease in ALT and AST enzyme levels which were close to normal values ​​in rats. Histological observation showed extensive damage to liver cell tissue, with signs of inflammation, hemorrhage, necrosis, and hydropic degeneration. By giving high doses of Ajwa date palm extract and Meloxicam 30mg/kgBW, gave a view of a decrease degree on liver tissue damage. Conclusion: The extract of Ajwa date palm (Phoenix Dactylifera L.) can provide a protective effect against liver damage in white rats (Rattus Norvegicus) induced by Meloxicam with decreased levels of liver function enzymes which are Alananine Transaminase (ALT) and Aspartate Aminotransferase (AST), along in the changes of liver histopathological view which showed a decrease degree of liver cell tissue damage. Keywords: Ajwa date palm extract; Meloxicam; Liver tissue damage.
Effect of Noise Stress Exposusre on Heart Histopathology of White Rat (Rattus Norvegicus) Rarasmika, Ainun; Andini, Nurul Sulfi; Fatmawati, Dian; Musdalifah; Sari, Dwi Kesuma; Purba, Fika Yuliza
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 8 No. 1, JANUARY 2024
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jrvi.v8i1.28495

Abstract

Noise is one of stressors that can occur over a long period and adversely affect health if it exceeds the ability to adapt. The heart plays a significant role and is the main organ in distributing oxygen, substances, minerals, and other organic substances in the blood. The samples used in this study amounted to 24 white male rats divided into four groups. Group K1 is a control rat that does not give treatment, Group P1 is given noise treatment for 6 hours of exposure, Group P2 with 9 hours of exposure, and Group P3 with a dose of 12 hours of exposure. Heart samples were collected and histology preparations were obtain by Hematoxylin-Eosin (HE) staining, and microscopic observe were made with 10μm and 40μm magnification. The results of the study were then adjusted to degree of damage and analyzed using the Kruskall-Wallis test and the Mann-Whitney test to showing changes in the form of necrosis and inflammation due to noise stress with different levels of damage and obtained a value below the critical value (p<0.05). The degree of damage that occurs is in line with the length of noise exposure given. Severe damage occurred in Group 3 with noise exposer of 12 hours/day for 29 days.
The Palatability Level of the Application of Animal Welfare Aspects in Laboratory Animal Management at the Animal Lab of Hasanuddin University Veterinary Teaching Hospital AMRIANI, RINI; A. MUH. ICHLASUL AKMAL; MUHAMMAD DIRGA GIFARDI; DIDIK IMAM SAKIRIN; DWI KESUMA SARI; A. MAGFIRA SATYA APADA
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 9, No. 2, JULY 2025
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jrvi.v9i2.42802

Abstract

According to Law Number 18 of 2009, animal welfare encompasses all aspects related to the physical and mental condition of animals based on their natural behaviors. Animal welfare includes how the management of laboratory animal housing is evaluated in terms of cage conditions, environment, and nutritional fulfillment. The objective of this study is to examine the correlation between the application of animal welfare aspects, including housing management, environment, and nutrition, on the palatability levels of laboratory animals. The research method involved dividing the treatment groups into eight groups, with each group consisting of three rats, for a total of 24 rats. The rat groups were categorized based on housing management, which was assessed based on cage size and body weight, sterilized versus non-sterilized bedding, optimum versus non-optimum temperature and humidity, and the frequency of feeding once a day or twice a day. The results showed that groups one and two exhibited higher average palatability levels compared to the other groups (17.5 and 16.5 grams, respectively), while groups four and five exhibited the lowest palatability levels (10.5 and 11.5 grams). Normality tests indicated that the data were normally distributed (P>0.05), and homogeneity tests showed that the data from the different groups were consistent (homogeneous) (P>0.05). Based on the normality and homogeneity tests, statistical analysis (ANOVA) was conducted. The ANOVA results indicated a significant effect (P
The Effect of Sterilization on Vitamin D Levels in Male and Female Rats Pratiwi, Hamria; Idris, Irfan; Sari, Dwi Kesuma
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 6 No.1, JANUARY 2022
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Sterilization is an operation that can prevent reproduction and is useful as a treatment. Sterilization is done by removing the reproductive organs, in males it is called orchiectomy and in females it is called ovariohysterectomy which causes a decrease in the production of reproductive hormones. Previous studies have proven a physiologic relationship between reproductive hormones and vitamin D activation, but there is no information on the effect of sterilization on vitamin D levels. This study aimed to determine the effect of sterilization on vitamin D levels. This study was experimental with a Posttest-Only Control Group design. design. A total of 24 wistar rats consisting of 12 male rats and 12 female rats and each were divided into two groups, 6 female rats sterilized (ovariohysterectomy), 6 female rats non-sterilized, 6 male rats sterilized (orchiectomy) and 6 male rats non-sterilized. -sterilization. Wistar rats that were 10 weeks old were transferred to their respective cages and given regular feed to all groups of rats for 7 days as an adaptation process, after which sterilization was carried out in the sterilization group. After 6 weeks post-treatment, the rats were 17 weeks old and then blood was taken for examination of Vitamin D levels using the elisa method which was carried out at Hum-Rc Hasanuddin University Hospital. The results showed that the mean value of vitamin D levels in the ovariohysterectomy group was lower than in the non-sterilized group and was significant (Mann-Withney, p<0.05). The orchiectomy group was also lower than in the non-sterlized group and not significant (Independent T test, p> 0.05). It can be concluded that sterilization can reduce vitamin D levels in pets. Keywords: Sterilization, Ovariohysterectomy, Orchiectomy, and Vitamin D
PELATIHAN CAPCUT VIDEO EDITING UNTUK MENINGKATKAN SKILL DAN DAYA SAING MAHASISWA PENDIDIKAN DI DUNIA KERJA Mesra, Romi; Monica, Waode Santa; Anton, Erning Ertami; Sari, Dwi Kesuma
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 5 No. 3 (2024): Volume 5 No. 3 Tahun 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v5i3.30013

Abstract

Pelatihan CapCut Video Editing ini bertujuan untuk meningkatkan keterampilan dan daya saing mahasiswa pendidikan dalam membuat konten video edukatif yang menarik dan berkualitas. Kemampuan merancang dan menghasilkan video pembelajaran menjadi kompetensi penting bagi calon pendidik di era digital saat ini. Pelatihan dilaksanakan dengan pendekatan teori dan praktik. Peserta dibekali pengetahuan tentang konsep dasar video editing, fitur-fitur CapCut, serta prinsip desain instruksional untuk video pembelajaran. Metode instruksional meliputi ceramah, demonstrasi, praktik langsung di bawah bimbingan instruktur, serta penugasan proyek akhir membuat video pembelajaran. Evaluasi dilakukan melalui presentasi karya dan pemberian umpan balik. Setelah mengikuti pelatihan, peserta mampu mengoperasikan aplikasi CapCut dengan mahir, meliputi memotong video, menggabungkan klip, menambahkan efek visual, transisi, teks, dan audio. Peserta juga memahami prinsip-prinsip desain instruksional seperti penyusunan konten terstruktur, visualisasi menarik, gaya penyampaian bervariasi, serta elemen interaktif untuk menghasilkan video pembelajaran berkualitas. Karya proyek akhir menunjukkan penguasaan teknis dan konseptual peserta dalam merancang dan memproduksi video edukatif. Pelatihan ini meningkatkan keterampilan peserta dalam menggunakan multimedia untuk tujuan pembelajaran serta membekali mereka dengan kompetensi yang dibutuhkan di dunia kerja pendidikan.
The EFFECTIVENESS OF MANGO LEAF EXTRACT SUPPLEMENTATION (MANGIFERA INDICA L.) ON METABOLIC DISEASE PANEL OF WISTAR RATS (RATTUS NORVEGICUS) INDUCED BY HIGH-FAT DIET: Diabetes, Glucosa, Mango Leaf, Supplement Gilang, Gilang Ramadhan; Ramadhan K., Muhammad Zoel Vitra; Azzuhdi, Faiz Adlan; Azzahra, Nabila; Nurlina; Zahrani, Putri Dyah; Amriani, Rini; Sari, Dwi Kesuma; Bahmid, Nur Alif; Andini, Nurul Sulfi
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 10, No 1, JANUARY 2026
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jrvi.v10i1.48703

Abstract

High-calorie foods can cause obesity if consumed in excess. Obesity occurs due to excessive fat accumulation in the body. Excess weight is a major risk factor for secondary disorders in pets, such as diabetes mellitus. Diabetes mellitus occurs due to high blood glucose levels. Mango leaf extract contains bioactive compounds that can lower and normalise blood glucose levels and can be used as a supplement. This study aims to determine the effectiveness of mango leaf extract supplementation induced by a high-fat diet on blood glucose levels. This study used arumanis and golek mango leaf. The methods used were extraction and in vivo testing. Extraction was performed on mango leaf, and the extraction results were administered to test animals in vivo. The phytochemical results showed that arumanis and golek mango leaf contain flavonoids, tannins, alkaloids, and saponins. The results showed that arumanis mango leaf extract was more effective in lowering blood glucose levels than golek mango leaf extract. These findings are expected to contribute to the development of knowledge about supplements and drug substitutes, as well as to identify more practical methods for drug therapy for diabetes mellitus in pets.
Co-Authors A. Magfira Satya Apada A. MUH. ICHLASUL AKMAL Abdul Halim, Musdalifah Abdul Wahid Jamaluddin Adryani Ris Adyatma Muhammad Nur Alni, Nurul Istiana Amriani, Rini Andi Magfira Satya Apada Andini, Nurul Sulfi Annita Vury Nurjunitar Aras, Irwin Arif, Makruf Arsyad, M Aryadi Astri Caturutami Sjahid Azzahra, Nabila Azzuhdi, Faiz Adlan Bahmid, Nur Alif Bambang Pontjo Priosoeryanto Baso Yusuf Cangara, Husni Dedy Rendrawan Dewi Mutisari Dewi Ratih Agungpriyono Dian Anugrah Dian Fatmawati DIDIK IMAM SAKIRIN Dini Marmansari Djabir, Yulia Yusrini Erdi Purwanto Erning Ertami Anton Fachira Ulfa Makmur Fatimah Mappanyompa Fatmawati, Dian Fedri Rell Ferra Indrawati Fika Yuliza Purba Gilang, Gilang Ramadhan Hartarto Akhmad Hendra Wibawa Ilham Akbar Rahman IRFAN IDRIS Irfan Idris Irfan Idris Irma Andriani Ismartoyo (Ismartoyo) Kazuyuki Uchida Ketut Adnyane Mudite Khusnul Yakin Kusumaningrum, Arsyinta Retno Lellah Rahim Magfira Satya Mufidatul Asmi Muflihanah Muh. Nasrum Massi MUHAMMAD DIRGA GIFARDI Muhammad Fadhil Shalih Muhammad Fadhlullah Mursalim Muhammad Hatta Muhammad Muflih Nur Muhammad Syukur Hamdan Muhammad Zulfadhillah Sinusi Natsir, Sartini Novi Susanty Nurlaila Fitriani Nurlina Nurmauliah Syaharuddin Pratiwi, Hamria Purba, Fika Yuliza Ramadhan K., Muhammad Zoel Vitra Rarasmika, Ainun Rasdiyanah Rasdyanah Rasdyanah Ratna Romi Mesra Ryoji Yamaguchi Sartini Natsir Savitri Novelina Sitti Mughniati Sri Deniati Srihadi Agungpriyono Suanti Supri Susumu Tateyama Tutik Wresdiyati Wahyuni Wahyuni WAODE SANTA MONICA Yulia Yusrini Djabir Zahrani, Putri Dyah