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1D and 2D Feature Extraction Based on AAC and DC Protein Descriptors for Classification of Acetylation in Lysine Proteins using Convolutional Neural Network Faisal, Mohammad Reza; Adawiyah, Laila; Saragih, Triando Hamonangan; kartini, Dwi; Herteno, Rudy; Lumbanraja, Favorisen Rosyking; Handayani, Lilies; Solechah, Siti Aisyah
Journal of Electronics, Electromedical Engineering, and Medical Informatics Vol 6 No 4 (2024): October
Publisher : Department of Electromedical Engineering, POLTEKKES KEMENKES SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35882/jeeemi.v6i4.458

Abstract

Post-Translational Modification (PTM) denotes a biochemical alteration observed in an amino acid, playing crucial roles in protein activity, functionality, and the regulation of protein structure. The recognition of associated PTMs serves as a fundamental basis for understanding biological processes, therapeutic interventions for diseases, and the development of pharmaceutical agents. Using computational approaches (in silico) offers an efficient and cost-effective means to identify PTM sites swiftly. The exploration of protein classification commences with extracting protein sequence features that are subsequently transformed into numerical features for utilization in classification algorithms. Feature extraction methodologies involve using protein descriptors like Amino Acid Composition (AAC) and Dipeptide Composition (DC). Yet, these approaches exhibit a limitation by neglecting crucial amino acid sequence details. Moreover, both descriptor techniques generate a limited number of 1-dimensional (1D) features, which may not be ideal for processing through the Convolutional Neural Network (CNN) classification method. This investigation presents a novel approach to enhance feature diversity through protein sequence segmentation techniques, employing adjacent and overlapping segment strategies. Furthermore, the study illustrates the organization of features into 1D and 2D formats to facilitate processing through 1D CNN and 2D CNN classification methodologies. The findings of this research endeavour highlight the potential for enhancing the accuracy of acetylation classification in lysine proteins through the multiplication of protein sequence segments in a 2D configuration. The highest accuracy achieved for AAC and DC-based feature extraction methods is 77.39% and 76.75%, respectively.
The Relationship between Physical Activity and The Level of Physical Fitness of Pencak Silat Athletes Mubarak, Jamil; Yudistira, Sigit; Solechah, Siti Aisyah; Norhasanah, Norhasanah
Sport and Nutrition Journal Vol 5 No 1 (2023): Sport and Nutrition Journal
Publisher : Nutrition Study Program, Faculty of Medicine, Universitas Negeri Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/spnj.v6i1.74253

Abstract

This study analyzed the relationship between macronutrient intake, hydration status, physical activity, and the physical fitness level of Pencak silat athletes in Banjarbaru. This analytical observational study used a cross-sectional design involving 30 pencak silat athletes selected using a total sampling technique. The research instruments included questionnaires, 24-hour food recall forms, a self-urine examination (PURI), a physical activity questionnaire, and a 12-minute running test. Data were analyzed using the Spearman Rank test. The results of this study indicated that most athletes had protein, fat, and carbohydrate deficiencies, moderate hydration status, and very light physical activity levels. It can be concluded that macronutrient intake, namely protein (p=0.264), fat (p=0.643), carbohydrates (p=0.101), and hydration status (p=0.264), had no association with the physical fitness levels of pencak silat athletes, while physical activity (p =0.010) had an association with the physical fitness level of Pencak silat athletes. Athletes are recommended to continue to pay attention to macronutrient intake and hydration status as needed because they also play an essential role in fitness apart from physical activity.
Hubungan Kecukupan Zat Besi, Asam Folat, Pengetahuan dan Sosial Ekonomi dengan Kejadian Anemia pada Ibu Hamil di Wilayah Landasan Ulin Timur: The Relationship Between Iron Sufficiency, Folic Acid, Knowledge and Socio-Economic to Incidence of Anemia Among Pregnant Women in East Landasan Ulin Norwahidah, Norwahidah; Solechah, Siti Aisyah; Yulianti, Yulianti; Suryani, Nany
Jurnal Ilmu Gizi dan Dietetik Vol 2 No 3 (2023)
Publisher : Departemen Gizi Masyarakat, Fakultas Ekologi Manusia, IPB dan PERGIZI PANGAN Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25182/jigd.2023.2.3.160-167

Abstract

Penelitian ini bertujuan untuk menganalisis hubungan kepatuhan zat besi, asam folat, pengetahuan, dan sosial ekonomi dengan kejadian anemia pada ibu hamil di wilayah Landasan Ulin Timur. Penelitian ini merupakan penelitian observasional analitik menggunakan desain cross-sectional. Penelitian ini dilakukan di Landasan Ulin Timur dari September 2022-Januari 2023. Sebanyak 19 ibu hamil dipilih sebagai sampel penelitian menggunakan metode total sampling. Kadar Hb ibu hamil didapatkan dari buku KIA. Data kepatuhan zat besi dan asam folat dikumpulkan melalui wawancara menggunakan semi-quantitative FFQ. Data pengetahuan dan sosial ekonomi dikumpulkan melalui wawancara menggunakan kuesioner. Hasil uji statistik menggunakan uji rank spearman pada tingkat kemaknaan 95% (p<0,05). Seluruh subjek (100%) memiliki kepatuhan zat besi yang cukup, kepatuhan asam folat cukup (84%), pengetahuan cukup (63%), pendidikan cukup (74%) dan pendapatan keluarga cukup (74%). Hasil penelitian ini menunjukkan bahwa kepatuhan zat besi (p=0,223), kepatuhan asam folat (p=0,599), pengetahuan (p=0,612), pendidikan (p=0,209) dan pendapatan keluarga (p=0,630) tidak berhubungan dengan kejadian anemia pada ibu hamil di wilayah Landasan Ulin Timur.
Pengetahuan, Sikap, dan Praktik Terkait Hipertensi serta Asupan Natrium dan Kalium Penderita Hipertensi di Puskesmas Kuaro, Kabupaten Paser, Kalimantan Timur: Knowledge, Attitudes, and Practices Related to Hypertension, Sodium and Potassium Intakes in People with Hypertension in Puskesmas Kuaro, Paser Regency, East Kalimantan Norkhasanah, Isni; Solechah, Siti Aisyah; Yulianti, Yulianti; Nisa, Ainun
Jurnal Ilmu Gizi dan Dietetik Vol 2 No 3 (2023)
Publisher : Departemen Gizi Masyarakat, Fakultas Ekologi Manusia, IPB dan PERGIZI PANGAN Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25182/jigd.2023.2.3.214-220

Abstract

Hipertensi merupakan kondisi dimana tekanan darah sistolik ≥140 mmHg atau tekanan diastolic ≥90 mmHg. Faktor-faktor risiko hipertensi antara lain usia, riwayat keluarga, konsumsi makanan asin, konsumsi lemak jenuh, kurangnya aktivitas fisik, obesitas, dan penggunaan pil KB. Penelitian ini bertujuan untuk memberikan gambaran tentang pengetahuan, sikap, dan praktik terkait hipertensi serta asupan natrium dan kalium pada penderita hipertensi. Penelitian ini dilakukan di Puskesmas Kuaro, Kabupaten Paser dari Januari hingga April 2022. Populasi penelitian ini adalah 223 penderita hipertensi. Responden penelitian ini adalah 67 orang yang dipilih mengunakan metode purposive sampling. Tekanan darah diukur menggunakan sfigmomanometer digital. Data pengetahuan, sikap, dan praktik terkait hipertensi dikumpulkan menggunakan kuesioner. Data asupan natrium dan kalium dikumpulkan menggunakan FFQ semi-kuantitatif. Data dianalisis secara deskriptif. Sebagian besar responden memiliki pengetahuan yang baik (80,6%), sikap yang cukup (53,7%), praktik yang cukup (64,2%), asupan natrium yang cukup (68,7%), dan asupan kalium yang kurang (76, 1%).
PROPORSI DAN FAKTOR RISIKO SINDROM METABOLIK PADA PEKERJA WANITA DI PABRIK GARMEN DI KOTA BOGOR Siti Aisyah Solechah; Dodik Briawan; Lilik Kustiyah
Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) Vol. 37 No. 1 (2014)
Publisher : Persagi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/pgm.v37i1.4005.21-32

Abstract

ABSTRACTMany studies on metabolic syndrome (MetS) in Indonesia were conducted but the study on female workers was scarce. The aim of this study was to obtain the proportion of MetS and its risk factors. Study design was cross-sectional and a number of 59 female workers aged 25-49 years at garmen factory in Bogor, West Java was pregnant or breastfeed women participated in this study. Collected data included blood pressure, serum level of triglyceride, high density lipoprotein (HDL), fasting blood glucose, activity, food consumption, anthropometry (weight and height) and social economic.The results showed that the proportion of MetS was 18,6 percent and family size was the significant risk factor for MetS (p<0.05; OR for family size = 6.286; 95% CI: 1.270 -31.102). Physical activity level and nutrient adequacy were not shown as risk factors. This result implied that controlling family size might be important to reduce prevalence of MetS among female workers in Indonesia.Keywords: metabolic syndrome, proportion, risk factors, female workersABSTRAKPenelitian mengenai sindrom metabolik (SM) telah banyak dilakukan di Indonesia tetapi penelitian yang berfokus pada pekerja wanita masih jarang dilakukan. Oleh karena itu, penelitian ini bertujuan untuk memperoleh proporsi SM dan faktor-faktor risikonya. Penelitian berdesain potong lintang ini dilakukan pada 59 pekerja wanita berusia 25-49 tahun di pabrik garmen Bogor, Jawa Barat yang tidak sedang hamil atau menyusui. Data yang dikumpulkan termasuk tekanan darah, kadar trigliserida, profil lemak (HDL), gula darah puasa, aktivitas, konsumsi makanan, antropometri (berat dan tinggi badan) dan data sosial ekonomi. Hasil penelitian ini menunjukkan bahwa proporsi SM pada pekerja wanita sebesar 18,6 persen dan besar keluarga agaknya merupakan faktor risiko SM yang signifikan (p<0,05; OR untuk besar keluarga = 6,286; interval kepercayaan 95%: 1,270-31,102). Tingkat aktivitas fisik dan kecukupan zat gizi tidak terlihat sebagai faktor risiko SM. Hal ini menunjukkan bahwa agaknya pengontrolan besar keluarga dapat menjadi langkah penting untuk menurunkan proporsi SM pada pekerja wanita di Indonesia. [Penel Gizi Makan 2014, 37(1): 21-32].Kata kunci: sindrom metabolik, proporsi, faktor risiko, pekerja wanita
SOSIALISASI DAN PEMBENTUKAN PEER EDUCATOR REMAJA PUTRI SEBAGAI UPAYA MENANGGULANGI ANEMIA DI DESA SUNGAI TABUK KERAMAT Solechah, Siti Aisyah; Rahmah, Zulfa Nur Haliza; Safitri, Eva Dwi; Qamra, Hasna Luthfiyyah; Rizky, Karin Carolina Amanda
Jurnal Abdi Insani Vol 12 No 7 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i7.2640

Abstract

Anemia is a serious health issue among adolescent girls, with one of the main causes being the low intake of iron supplements (Tablet Tambah Darah/TTD). In South Kalimantan, the prevalence of anemia in adolescent girls reaches 53.3%, yet TTD consumption coverage remains low. In Sungai Tabuk Keramat Village, 56.7% of adolescent girls had not received TTD in the past year. This community service program aimed to increase knowledge and compliance with TTD intake through the establishment of peer educators. Activities included health education, training on the use of hemoglobin (Hb) measuring devices, peer educator development, and 2.5 months of monitoring. The results showed that 92% of participants improved their knowledge of Hb device usage, and 92% of those re-tested achieved normal Hb levels. Monitoring of TTD consumption recorded that 31.6% of adolescents adhered to recommended intake in August, but this declined to 15.8% in September. This program proved effective in enhancing knowledge and hemoglobin levels among adolescent girls and demonstrated that peer educators can serve as effective educational agents. However, maintaining long-term adherence to TTD intake remains a challenge. Therefore, continuous support, increased involvement of families and health cadres, and strengthened monitoring systems are essential to sustain the program’s impact and contribute significantly to anemia prevention among adolescent girls.
FAKTOR RISIKO IBU DENGAN KEJADIAN ANEMIA PADA IBU HAMIL DI PRAKTIK MANDIRI BIDAN (PMB) DEWI ARIYANI, S.ST Misna Tazkiah; Isti Qomah; Siti hardiyanti; Siti Aisyah Solechah; Nurul Hidayah
Jurnal Intelek Dan Cendikiawan Nusantara Vol. 1 No. 3 (2024): JUNI - JULI 2024
Publisher : PT. Intelek Cendikiawan Nusantara

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Anemia in pregnancy is a clinical problem that is often encountered in developing countries. Anemia in pregnancy is a global major concern because it results in increased incidence of mortality and morbidity for mothers and infants. There are still anemic pregnant women whose gestational age and parity are different. This study aimed to analyze the risk factors associated with the incidence of anemia in pregnant women at the PMB of Dewi Ariyani, S.Si.T. This observational study used a case control approach with a case:control ratio of 1:2. A total of 36 research samples participated in this study, consisting of 12 people in the case group and 24 in the control group. Data were analyzed using the chi-square test with an α of 0.05. The results showed that the most pregnant women (83.3%) were 20-35 years and did not work (79.2%). Parity was associated with the incidence of anemia in pregnant women (p=0.012; OR 9.000; 95% CI: 1.817-44.591), and gestational age was also associated with the incidence of anemia (p=7.286; OR 9.000; 95% CI: 1.508-35.211). Besides taking blood supplement tablets regularly, pregnant women with anemia are also advised to increase the consumption of foods that contain iron, such as green-leafy vegetables.
RISK FACTORS OF ANEMIA IN ADOLESCENT GIRLS IN WETLAND AREAS: A STUDY IN SOUTH KALIMANTAN Yulidasari , Fahrini; Solechah, Siti Aisyah; Setiawan , Muhammad Irwan; Anhar, Vina Yulia; Noor, Ihya Hazairin; Santoso, Izal Puji; Fatimah, Husnul
Indonesian Midwifery and Health Sciences Journal Vol. 9 No. 4 (2025): Indonesian Midwifery and Health Sciences Journal, October 2025
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v9i4.2025.391-400

Abstract

Background: Anemia in adolescent girls is a global and national public health problem that is receiving increasing attention due to the high nutritional needs during growth and iron loss during menstruation. Preliminary data from wetland areas, particularly in Sungai Alang Village, Banjar Regency, shows a prevalence of anemia of 23.54%. This study aims to analyze risk factors associated with anemia in adolescent girls, including age, education level, nutritional knowledge, dietary behavior, and nutritional status based on Mid-Upper Arm Circumference (MUAC) and Body Mass Index (BMI). Method: This study used an observational analytical design with a cross-sectional approach in 50 adolescent girls aged 12–24 years selected through purposive sampling. Data were obtained through questionnaires and hemoglobin level measurements using an Hb meter. Analysis was performed using Spearman's rho correlation test and multivariate linear regression. Result: The results showed a prevalence of anemia of 34%, exceeding the threshold for a moderate public health problem according to the WHO. Bivariate analysis found a significant negative correlation between age and Hb levels (r=-0.405; p=0.004) and a significant positive correlation between MUAC and Hb levels (r=0.373; p=0.008). Meanwhile, knowledge, BMI, and dietary behavior did not show a significant correlation. Multivariate analysis identified age (β=-0.459; p=0.000), MUAC (β=0.599; p=0.000), and BMI (β=-0.354; p=0.033) as significant independent predictors. Conclusion: The results confirmed that anemia in adolescent girls is influenced by physiological factors and anthropometric status, while knowledge and dietary behavior do not play a direct role. Therefore, preventive interventions need to be carried out holistically through supplementation, targeted nutrition education, and other supporting health programs.
Telemedicine and AI in Remote Prediabetes Monitoring Among Adolescents Solechah, Siti Aisyah; Saputro, Setyo Wahyu; Adini, Muhammad Hifdzi; Faisal, Mohammad Reza; Kurniawan, Erick; Umiatin, Umiatin
Indonesian Journal of Electronics, Electromedical Engineering, and Medical Informatics Vol. 8 No. 1 (2026): February
Publisher : Jurusan Teknik Elektromedik, Politeknik Kesehatan Kemenkes Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35882/ijeeemi.v8i1.283

Abstract

The escalating prevalence of prediabetes in Indonesia, particularly among children and adolescents, necessitates the development of lightweight, adaptable, and cost-effective telemedicine solutions for the noninvasive monitoring of blood glucose levels. Existing systems predominantly employ machine learning and deep learning approaches that require substantial computational resources and stable internet connectivity, limiting their applicability in regions with constrained digital infrastructure. The objective of this study is to develop an artificial intelligence (AI)–driven telemedicine system that employs an expert system to determine prediabetes status by utilizing commercially available smartwatches as noninvasive optical sensors. The methodological approach includes an examination of smartwatch capabilities to identify Bluetooth Low Energy (BLE) sensors, service architectures, and the Generic Attribute Profile (GATT); the development of a Rule-Based Reasoning (RBR) expert system to determine prediabetes status using Fasting Plasma Glucose (FPG) and Postprandial Plasma Glucose (PP2) measurements; and the application of Rapid Application Development (RAD) methods in the development of Flutter-based mobile applications and Laravel Inertia Vue–based web applications. The results of this study demonstrate that the telemedicine system operates in both offline and online modes and incorporates AI functionality on mobile devices and servers without requiring extensive computational resources. All system functionalities successfully passed testing, and the expert system achieved 100% accuracy in determining prediabetes status. In conclusion, the integration of telemedicine and AI-based expert systems provides an effective, economical, and flexible solution that can be widely implemented in Indonesia to reduce the increasing incidence of prediabetes through continuous digital health monitoring.
Nutrition Education Regarding Physical Activity to Prevent Obesity Among Adolescents at State Islamic Senior High School 4 Banjar Solechah, Siti Aisyah; Ali, Indra Haryanto; Setiawan, Muhammad Irwan; Yulidasari, Fahrini; Rahayu, Atikah; Tazkiah, Misna
Jurnal Publikasi Kesehatan Masyarakat Indonesia Vol 11, No 2 (2024): Jurnal Publikasi Kesehatan Masyarakat Indonesia
Publisher : Lambung Mangkurat University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jpkmi.v11i2.19656

Abstract

Lack of physical activity is one of the behaviors associated with non-communicable diseases. Physical activity levels decreased among individuals aged ten and above in South Kalimantan. The proportion of this problem also increased sharply in Banjar Regency. Discussions with the school showed that students at the school lacked physical activity. Nutrition education regarding physical activity has never been conducted at this school. This activity aimed to increase adolescents’ knowledge about the importance of physical activity in preventing obesity. It was conducted at Islamic Senior High School 4 Banjar, involving 67 members of the Youth Red Cross. Nutrition education was performed through lectures using PowerPoint slides. Participants' knowledge was assessed using pretest and posttest questionnaires. There was a significant knowledge difference (p<0.05) before and after the education. A total of 61 people had a higher score than before the education. A total of 52.2% of participants had poor knowledge, and 47.8% had moderate knowledge before education. After education, 58.2% had high knowledge, 38.8% had moderate knowledge, and 3% had low knowledge. It indicated that nutrition education is effective in increasing participants' knowledge.