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Journal : Sanus Medical Journal

Gambaran Quantitative Electroencephalography (QEEG) Anak Laki-laki Penderita Attention-Deficit Disorder (ADD) Pandhita S, Gea; Sutarni, Sri
Sanus Medical Journal Vol. 2 No. 1 (2021)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v1i1.6610

Abstract

Background. The Diagnostic and Statistical Manual of Mental Disorders (DSM) grouping the types of ADD is based on the clinical symptoms of neurobehavioral disorders, regardless of the possible underlying etiology. This means that the same ADD type group may have a different etiology of functional brain disorders. Meanwhile, QEEG has been known to describe the possible etiology that underlies an ADD event. This study aims to identify differences in QEEG features in the same ADD type group. Methods. Subjects consisted of 40 boys with ADD. QEEG was recorded from 21 sites, and Fourier transformed to provide estimates for relative power in the delta, theta, alpha, and beta bands in the frontotemporal and central regions. These data were converted to Z-scores based on the normal value data; afterward, they were subjected to cluster analysis. Independent sample t-tests were used to determine how the total ADD group and the ADD cluster subgroups differed from the normal value. Results. The total ADD group had increased relative delta (Z-score-frontotemporal region = 3,26 ± 1,59; Z-score-central region = 4,04 ± 1,71), decreased relative alpha (Z-score-frontotemporal region = -2,78 ± 1,29; Z-score-central region = -2,86 ± 1,36), decreased relative beta (Z-score-frontotemporal region = -5,33 ± 1,61; Z-score-central region = -6,19 ± 1,86), increased rasio teta/alpha (Z-score-frontotemporal region = 2,806 ± 1,41; Z-score-central region = 2,59 ± 1,26), and increased rasio teta/beta (Z-score-frontotemporal region = 4,36 ± 1,69; Z-score-central region = 4,94 ± 1,46). Two distinct QEEG clusters subgroups were found. The first cluster was characterized by increased central relative delta (Z-score-central region = 3,02 ± 1,17), decreased relative beta (Z-score-frontotemporal region = -4,29 ± 0,73; Z-score-central region = -5,06 ± 1,19) and increased rasio teta/beta (Z-score-frontotemporal region = 3,83 ± 1,91; Z-score-central region = 4,94 ± 1,96). The second cluster was characterized by increased relative delta (Z-score-frontotemporal region = 4,71 ± 1,02; Z-score-central region = 5,72 ± 0,98), decreased relative alpha (Z-score-frontotemporal region = -3,92 ± 1,12; Z-score-central region = -4,24 ± 0,69), decreased relative beta (Z-score-frontotemporal region = -7,08 ± 1,06; Z-score-central region = -8,09 ± 0,99), increased rasio teta/alpha (Z-score-frontotemporal region = 3,08 ± 1,04; Z-score-central region = 2,86 ± 1,02), and increased rasio teta/beta (Z-score-frontotemporal region = 5,23 ± 1,16; Z-score-central region = 5,71 ± 1,35) Conclusions. These results indicate that boys with ADD do not constitute a homogenous group in QEEG profile terms. Two distinct QEEG clusters were found. The first cluster was typified by a cortically hypoaroused, while the second cluster was typified by a maturational-lag in central nervous system development. This difference in possible etiology may have implications for studies of the utility of QEEG in the diagnosis of ADD and the differences in therapeutic response between the two groups.
Co-Authors Abdul Gofir Abidah Rohmatillah Ahmad Syafi'i Ma'arif Amelia Nur Vidyanti Anam Sutopo Anis Mahmudah Anis Mahmudah, Anis Antok Aryuana Aprilianto, Muhamad Farhan Ardelia, Berliani Aulia, Syafira Nur Azmi Bayuangga, Halwan Fuad Cahyaningtyas, Putri Charomah Sri Setianing Rahayu Damastuti, Ayun Siwi Dina Maulita Efi Maysaroh Emese Kovácsné Nagy Erlina, Diah Ayu Fafria Fari Hastuti Ferdianto, Juli Gatiniggsih, Rustiwi Harun Joko Prayitno Hasan, Titis Rohmat Hasnawati, Zakiyah Hastuti , Windi Hayati, Hanifah Fajarisna Hermawati Hermawati, Hermawati Hidayati, Miftachul Hindarto Indarwati Indarwati Irmanopaliza, Ade Ismail Setyopranoto Jasno, Jasno Khairunnisaa', Danik Martha Kurniawan Budi Santoso, Kurniawan Budi Laksmiwati, Pasttita Ayu Lestari, Enur Rara Lina Listiana Maghdhuroh, Umi Mahmudah, Mutiara Hisda Mairina, Upik Masduki Masduki Masduki Maulida, Dini Wardani Mawaddah Ar-Rochmah Muhamad Arief Rahman Muhamad Farhan Aprilianto Muhamad Toyib Muhammad Kholid Muhammad Noor Kholid Muhammad Toyib, Muhammad Nagy, Emese Kovácsné Nathania, Caroline Evanthe Nida Sri Utami Nining Setyaningsih Nuqthy Faiziyah Nur Rohman Nur Rohman Pamungkas, Haris Wahyu Pandhita S, Gea Paryono Pasttita Ayu Laksmiwati Peni Suharti Prabandari, Radha Sita Pratama, Muhammad Alif Prodjohardjono, Astuti Puteri, Mei Yunika Putri, Reni Widya Putri, Vega Pratiwi Qhadhavy Putri, Iqlima Khartini Radha Sita Prabandari Rania, Nadhifa Riayuliatun, Evi Rita P Khotimah, Rita P Rita Pramujiyanti Khotimah Rita Rahmaniati Rusdijanto, Titania Alya Ruspeni Daesusi Salsabila Nur Faizzah Santosa, Yoga Tegar Satiti, Sekar Setyaningrum, Cempaka Thursina Srie Setyaningsih, Indarwati Silalahi, Lothar Matheus Manson Vanende Sri Rejeki Subagya Subagya, Subagya Subagya, Nanang Legawa Suharti, Peni Susianti, Noor Alia Sutama Toyib, Muhamad Trihapsari, Nadia Trisni, Rizka Umi S. Intansari Ida Savitri Laksanawati Wibowo, Eko Ari Widiantoro, Rulli Yolanda Ika Damayati Yulia Maftuhah Hidayati Yusuf Zakaria Zakaria, Yusuf