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All Journal Jurnal Ilmu Dasar Jurnal Penelitian Pendidikan IPA (JPPIPA) Indonesian Journal of Chemistry JMM (Jurnal Masyarakat Mandiri) Edukasi Islami: Jurnal Pendidikan Islam Jurnal Kreativitas PKM Molekul: Jurnal Ilmiah Kimia International Journal for Educational and Vocational Studies JCER (Journal of Chemistry Education Research) Kumawula: Jurnal Pengabdian Kepada Masyarakat JPPS (Jurnal Penelitian Pendidikan Sains) Jurnal Abdi: Media Pengabdian Kepada Masyarakat Jurnal Abdimas Bina Bangsa Bulletin of Pedagogical Research Jurnal Pijar MIPA Jurnal Pengabdian Teratai Molekul: Jurnal Ilmiah Kimia JUMANDIK Jurnal Akademika Kimia Jurnal Manajemen & Pendidikan Al Ilmu Jurnal Pendidikan MIPA
Tukiran Tukiran
Department of Chemistry, Faculty of Mathematics and Sciences, State University of Surabaya. Jl. Ketintang Surabaya East Java Indonesia-60231.
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Antioxidant of Effervescent Tablet Formulated from Combination of Secang Wood and Red Ginger Extracts Sofyah, Titik Mardiyanti; Tukiran, Tukiran; Sutoyo, Suyatno
Jurnal ILMU DASAR Vol 23 No 2 (2022)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/jid.v23i2.28136

Abstract

Secang wood has strong antioxidant properties because it contains phenolic compounds such as flavonoids and brazilin. Also, red ginger has antioxidant derived from nonvolatile phenolic compounds. Until now, there has been no use of a combination of secang wood extract and red ginger specifically for the manufacture of effervescent tablets. The purpose of this study was to formulate an effervescent tablet by doing combination of secang wood and red ginger extracts with using various concentrations of citric and tartaric acids. The formulations conducted were three acid sources of 20%, 25%, 30%, using wet granulation. The evaluation subjected to the formulas included the physical properties of the granules, such as the water content and flow properties of the granules. Meanwhile, the evaluation performed to the tablet included the hardness test, tablet friability, weight uniformity, dissolution time, and acidity (pH). The analysis was carried out in accordance with the requirements of the Indonesian Pharmacopoeia Edition III and BPOM. The results obtained are effervescent tablet with an acid variation of 20% with physical quality values of water content of 2.91% and granule flow properties of 6.03 s. Meanwhile, the physical quality requirements of effervescent tablets were tablet hardness of 4.02 kp; tablet friability 0.46%; weight uniformity 0.132%; 71 s dissolution time; and 6.4 degrees of acidity.
Rancang Bangun Alat Laminar Air Flow Cabinet dan Pendampingannya di UKM Thani Jamur Magetan Tukiran, Tukiran
Jurnal ABDI: Media Pengabdian Kepada Masyarakat Vol. 10 No. 1 (2024): JURNAL ABDI : Media Pengabdian Kepada masyarakat
Publisher : Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/abdi.v10i1.31645

Abstract

A survey conducted at Thani Oyster Mushroom UKM in Magetan, followed by interviews with the owners, revealed that the main challenges faced by UKM were frequent failures and difficulties in finding trusted partners who were able to prepare oyster mushroom seeds well. This is mainly caused by less than sterile room conditions and inadequate facilities. Typically, mushroom breeding consists of the following stages: The process involves four steps: 1) cultivating an uncontaminated culture, 2) creating a starter culture, 3) producing a primary seed culture, and 4) producing final production seeds. Partners often encounter challenges and setbacks when trying to cultivate this mushroom. Creating culture media is a crucial step in the process of preparing pure culture. To date, partners have utilized PDA as a specialized medium for cultivating single strains of microorganisms, and this has been achieved using less sterile equipment and facilities. As a result, the media will be contaminated by pest bacteria, weeds, and other elements that are difficult to avoid, resulting in low success rates and frequent failures. The alternative proposed in this PKM activity is the need to build an aseptic isolation room or enclosure, which is specifically known as a Laminar Air Flow Cabinet (LAFC). The instrument is equipped with a continuously operating ultraviolet light, TL lamp, blower and air filter to ensure a sterile working environment by removing dust, dirt, spores and other particles that inhibit the germination of fungal seeds. Initial support provided to partners in utilizing LAFC resulted in a success rate of approximately 77% (10 out of 13 petri bottles) in mushroom mycelium cultivation.
Dampak Intellectual Capital dan Leverage terhadap Profitabilitas pada PT Akasha Wira International Tbk Periode 2016-2020 Tukiran, Tukiran; Firstianto, Seno Aji; Muchtadin, Muchtadin; Irawan, Sani
Jurnal Manajemen & Pendidikan [JUMANDIK] Vol 2 No 1 (2023): Jurnal Manajemen & Pendidikan [JUMANDIK]
Publisher : LAP4B

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58174/jmp.v2i1.45

Abstract

Penelitian ini bertujuan untuk mengetahui dampak dari Intellectual Capital dan Leverage terhadap Profitabilitas pada PT Akasha Wira International Tbk periode 2016-2020. Jenis penelitian ini bersifat deskriptif kuantitatif. Populasi yang digunakan berupa laporan keuangan PT Akasha Wira International Tbk periode 2016-2020. Analisis data yang digunakan meliputi Intellectual Capital, Leverage dan Profitabilitas, uji deskriptif, uji asumsi klasik, uji hipotesis dan uji regresi linier berganda. Hasl uji t (parsial) diperoleh dampak Intellectual Capital berpengaruh terhadap Profitabilitas, dampak Laverage berpengaruh terhadap Profitabilitas. Hasil uji F (simultan), Intellectual Capital dan Leverage berpengaruh terhadap Profitabilitas.
OPTIMALISASI LIMBAH TONGKOL JAGUNG SEBAGAI PAKAN TERNAK MELALUI IMPLEMENTASI PAKET TEKNOLOGI PENGOLAH PAKAN PADA KELOMPOK TANI SIDO MAKMUR II TULUNGAGUNG Prabowo, Prayudi Setiawan; Wibowo, Theodorus Wiyanto; Tukiran, Tukiran; Pangestu, Puji Dwi; Pambudi, Rizdana Galih
Jurnal Abdimas Bina Bangsa Vol. 6 No. 1 (2025): Jurnal Abdimas Bina Bangsa
Publisher : LPPM Universitas Bina Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46306/jabb.v6i1.1544

Abstract

The corn plant has become a favorite of the farmer group “SIDO MAKMUR II” because it is resistant to pest attacks, suitable for planting in the dry season, and easy to maintain, providing significant benefits to farmers. However, the utilization of corn plant parts has not been maximized, particularly the use of corn cobs, which remains unexploited by the “SIDO MAKMUR II” group. According to Mr. Nurkolis, it is indeed unfortunate that corn cobs are either discarded or not utilized, given that this waste can be processed into high-quality animal feed. This is largely due to a lack of adequate tools and appropriate technology, as well as management issues, especially in bookkeeping for the business. To address these issues, the Community Partnership Empowerment Team from Universitas Negeri Surabaya is working to optimize corn cob waste as animal feed, aiming to resolve production problems in utilizing corn cob waste and issues in business management, particularly in savings and loans. The proposed solutions include (1) procuring and implementing a package of machines for processing corn cob waste into animal feed, (2) training on creating powdered corn cob feed through fermentation, and (3) training and assistance in implementing savings and loan management for the partners. The results of this community service activity, through the implementation of a technology package for processing corn cob waste into animal feed, show that the “SIDO MAKMUR II” group can now process corn cobs into animal feed using grinding and milling machines, as well as a ribbon screw mixer equipped with a timer and speed control. Additionally, there has been an improvement in management, particularly in the group’s finances, due to the establishment and training in business management.
Chemical Profiling Ethyl Acetate Extract of Basilicum polystachyon Leaves and Exploration of Anticancer SIRT1 Inhibitors Using In Silico Approach Tukiran, Tukiran; Raihan, Muhammad
Indonesian Journal of Chemistry Vol 25, No 1 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.96606

Abstract

Cancer significantly increases prevalence and mortality rate making it a serious health concern currently, including breast cancer. The development of new drugs is a major effort to solve the cancer problems. Natural products are the primary source of medicinal compounds believed to have lower toxicity and side effects than synthetic drugs. This research aimed to reveal the chemical profile of the ethyl acetate extract of Basilicum polystachyon leaves. Through an in silico approach, this research studied the anticancer mechanism against the sirtuin1 (SIRT1) at the molecular level. Molecular docking simulations were performed to understand the interaction behavior of potential compounds as SIRT1 inhibitors. Based on these results, 117 individual compounds were successfully identified in the ethyl acetate extract. Molecular docking simulation revealed that ten compounds could inhibit SIRT1 better than the control inhibitor, indicating that these compounds have potential as anticancer agents. The prediction of these compounds' physicochemical properties and pharmacokinetics showed promising results and fulfilled the medicinal compound's criteria. These findings can be the basis for the application of phytochemical compounds as anticancer drugs, specifically potential compounds in B. polystachyon leaves.
Building Islamic Economy Towards Golden Indonesia 2045 Tukiran, Tukiran; Rajab, Muhammad Arhan; Mas'ud, Ibnu
Al-Ilmu Vol. 1 No. 3 (2024): Al-ilmu - November
Publisher : PT. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/sxr7rd67

Abstract

This study examines the strategic role of Islamic economics in supporting the achievement of the Golden Indonesia Vision 2045, which targets inclusive economic growth, poverty alleviation, global competitiveness, and sustainable development. Through the principles of social justice, equitable distribution of wealth, and wise management of natural resources, Islamic economics offers solutions that are in line with these goals. This study uses a mixed methods approach, combining quantitative surveys and qualitative interviews to explore the public and stakeholders' understanding of Islamic economics and the challenges and opportunities in its development. The results show that although the majority of respondents have a good understanding of Islamic economics, there are still barriers to the use of Islamic financial products, including a lack of understanding and access. In addition, interviews with entrepreneurs, academics, and policymakers reveal the importance of Islamic financial literacy as a key to expanding community participation. The study concludes that Islamic economics has great potential to drive equitable, inclusive, and sustainable growth, but supportive policies and broader education are needed to maximize its contribution to the Golden Indonesia                                                                 Vision 2045.
KKN Pemberdayaan Masyarakat Pesisir dalam Bidang Pendidikan, Kesehatan dan Teknologi Informasi Untuk Mendukung Pengembangan Desa Wisata Kelawi Mandiri dan Berkelanjutan Rajab, Muhammad Arhan; Raidar, Usman; Tukiran, Tukiran
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 8, No 4 (2025): Volume 8 No 4 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v8i4.18672

Abstract

ABSTRAK Pengembangan desa wisata menjadi salah satu agenda prioritas pemerintah sebagai upaya untuk mendukung pengelolaan desa mandiri dan berkelanjutan. Desa Kelawi memiliki potensi lokal sumberdaya alam yang sangat besar dan dapat dimanfaatkan untuk meningkatkan perekonomian masyarakat. Oleh karena itu, tujuan kegiatan ini untuk memanfaatkan potensi sumberdaya alam Desa Kelawi guna meningkatkan taraf hidup masyarakat desa. Kegiatan pemberdayaan masyarakat ini dilaksanakan melalui metode pelatihan dan pendampingan masyarakat melalui rangkaian kegiatan seperti sosialisasi dan edukasi mengenai potensi lokal desa Kelawi dan pelatihan pembuatan cinderamata khas desa Kelawi. Hasil kegiatan diantaranya teridentifikasi potensi lokal batok kelapa yang dapat diolah menjadi produk kreatif dan bernilai ekonomis, tersedianya produk dari olahan batok kelapa seperti gantungan kunci, gelas, tatakan gelas, lampu meja, asbak, dan mangkuk yang dapat menjadi cinderamata khas Desa Wisata Kelawi. Kegiatan pemberdayaan masyarakat ini dapat menjadi salah satu strategi mendorong dan meningkatkan perekonomian masyarakat desa melalui pemanfaatan potensi lokal desa. Diharapkan adanya keberlanjutan program pada masa mendatang melalui sinergitas layanan pemerintah desa dengan melibatkan partisipasi masyarakat. Kata Kunci: Pemberdayaan, Potensi Lokal, Desa Kelawi   ABSTRACT The development of tourist villages is one of the government's priority agendas as an effort to support independent and sustainable village management. Kelawi Village has enormous local natural resource potential and can be utilized to improve the community's economy. Therefore, the aim of this activity is to utilize the natural resource potential of Kelawi Village to improve the standard of living of the village community. This community empowerment activity is carried out through training methods and community assistance through a series of activities such as outreach and education regarding the local potential of Kelawi village and training in making souvenirs typical of Kelawi village. The results of the activities include identifying the local potential of coconut shells which can be processed into creative and economically valuable products, the availability of products made from processed coconut shells such as key chains, glasses, coasters, table lamps, ashtrays and bowls which can become typical souvenirs of the Kelawi Tourism Village. This community empowerment activity can be a strategy to encourage and improve the economy of village communities through utilizing local village potential. It is hoped that the program will be sustainable in the future through the synergy of village government services involving community participation. Keywords: Empowerment, Local Potential, Kelawi Village
Effectiveness of Desmanthus virgatus Leaf Ethyl Acetate Extract and Antiviral Drugs as Antirabies Based on In Silico Study Hendrawan, Syahrul; Ambarwati, Cindy; Tukiran, Tukiran
Jurnal Pijar Mipa Vol. 20 No. 4 (2025): Special Issue
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v20i4.9024

Abstract

Rabies is a deadly viral disease that has no effective therapy after clinical symptoms appear. This study aims to evaluate the antirabies potential of the dominant compounds in the ethyl acetate extract of Desmanthus virgatus leaves, as well as several antiviral drugs, through an in silico approach. The extract was obtained through maceration and partitioning methods using ethyl acetate solvent, then analyzed using LC-MS, which identified 182 secondary metabolite compounds, and ten dominant compounds were selected for further analysis. These compounds, along with seven antiviral drugs, were docked against the rabies virus glycoprotein (PDB ID: 6LGX) using AutoDockTools 4.2.6 software. The docking results were analyzed based on the values of binding affinity, inhibition constant (Ki), and interaction with active amino acid residues.  Quercitrin and quercimeritrin were the dominant flavonoid glycosides in the ethyl acetate extract of D. virgatus leaves that showed binding affinity values of -8.45 kcal/mol and -8.10 kcal/mol, respectively. In addition, bictegravir and tegobuvir showed binding affinity values of -9.17 kcal/mol and -9.05 kcal/mol, respectively. Four compounds indicated potential as antirabies drugs. Pharmacokinetic feasibility tests using Lipinski parameters showed that most of the dominant compounds violated one or more parameters, especially the number of hydrogen bond donors/acceptors and molecular weight. However, such violations were also found in some antiviral drugs that have been used, such as remdesivir and darunavir. These results suggest that D. virgatus leaf extracts contain compounds with promising potential antirabies activity and deserve further investigation through in vitro and in vivo tests.
Development of a Project-Based e-Portfolio for Enhancing Critical and Creative Thinking Skills in Land Pollution and Waste Management Education Yuliaturosida, Eka; Suyono, Suyono; Tukiran, Tukiran; Satriawan, Muhammad
Jurnal Pendidikan MIPA Vol 26, No 1 (2025): Jurnal Pendidikan MIPA
Publisher : FKIP Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpmipa.v26i1.pp169-194

Abstract

Critical and creative thinking skills are the core of 21st century skills that learners must have to face global challenges. The ability to interpret, analyze, evaluate, inference, explanation, self regulation, think fluency, flexibility, originality and elaboration can shows the level of their critical and creative thinking ability. The research aims to develop e-portofolio for enchancing the critical and creative thinking ability of 8th level students at Junior High School by soil pollution and waste management education. The research used a one-group pretest-posttest experimental design. The validity of e-portfolios consists of construct and content validity. The practicality of e-portfolios was assessed based on student response questionnaires. The effectiveness of the e-portfolio was assessed through a test designed to measure their critical and creative thinking skills. After the e-portfolio trial, a test was conducted to enable the improvement of critical and creative thinking skills. This study used the Research and Development (R&D) method with the ADDIE model (Analysis, Design, Development, Implementation, and Evaluation) which is limited to three stages namely analysis, product design and development. The validity assessment used expert judgement. The design of e-portfolio learning media involves elements that are in accordance with the indicators of critical and creative thinking by providing feedback, self-assessment, peer assessment, self-reflection. The data generated in this study is the validity of e-portfolios to measure critical and creative thinking skills. Based on the profile analysis of critical and creative thinking skills of SMP Negeri 8 Purwosari students, it was found that there was an increase in the percentage of critical thinking skills of grade VIII students from 73.08% in the very low category (19 students) to 88.46% in the very high category (21 students). It was also found that the percentage of creative thinking ability of the largest VIII grade students was 69.23% in the very low category (18 students) to 46.15% in the very high category (12 students) after using e-portfolios. This research developed e-portfolios as an innovative instrument that not only measures critical or creative thinking ability separately, but also learns both critical and creative thinking ability . In its implementation, the e-portfolio is designed to integrate various learning components, such as problem-based assignments, case studies, experiments and self-reflection that are relevant to practising critical and creative thinking skills.       Keywords: critical thinking ability, creative thinking ability, e-portfolio, pancasila student profile.
Implementation of Predict-Observe-Explain (POE) Strategy to Reduce Misconception in Thermochemistry Zakiyah, Imroatuz; Widodo, Wahono; Tukiran, Tukiran
International Journal for Educational and Vocational Studies Vol. 1 No. 7 (2019): November 2019
Publisher : Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/ijevs.v1i7.1757

Abstract

This research aims to determine that the implementation of the POE (predict-observe-explain) strategy can be used to correct misconceptions in thermochemistry. This research uses One Group Pretest-Posttest Design. This research was conducted in class XI MIA 5 students at Bhayangkari 3 Porong Senior High School. The sample used was 33 students who were divided into 6 heterogeneous groups. The students are given a conceptual understanding test as pretest and posttest in the form of a three-tier diagnostic test which amounts 20 questions. After pretest the next stage is to do remediation given learning process using worksheet of POE strategy. Then the results of pretest and posttest were then analyzed using Wilcoxon signed rank test. The result is POE (predict-observe-explain) strategy can be used to correct misconceptions in thermochemistry sub-topic for students in class XI of Bhayangkari 3 Porong Senior High School. This is indicated by a decrease in the percentage of students' misconceptions from 66.36% to 6.36%. In addition, based on the Wilcoxon Sign Rank Test, Asymp. Sig (2-Tailed) has 0 value, it means hypothesis 0 is rejected, which means there is a significant influence on the implementation of learning with POE strategies to improve the students status of knowing the concept.
Co-Authors A.A. Ketut Agung Cahyawan W Ali Imron Amalia Ruhana, Amalia Ambarwati, Cindy Andika Pramudya Wardhana Bahri, Moh Saiful Biyan Yesi Wilujeng Constanty, Irene Cornelia Dewi, Dyah Utami Dian Anisa Rokhmah Wati ERMAN ERMAN Farkiyah, Lilik Fida Rachmadiarti Firstianto, Seno Aji Hadiwidodo, Suryanto Harun Nasrudin Hendrawan, Syahrul Hendrawan, Syahrul Lerry I GUST MADE SANJAYA Ika Fatmawati Pramasari Irawan, Sani ISMONO ISMONO Kuniyoshi Shimizu Kusumawati Dwiningsih Leny Yuanita Luthfi Faza Afina Riza Walida, Luthfi Mas'ud, Ibnu Meilasari , Renita Meilasari, Renita Mispani, Mispani Mitarlis Mitarlis Mohamad Nur Muchtadin, Muchtadin Muhammad Arhan Rajab MUSLIMIN IBRAHIM Ngubad, Khumaidul Noerlina Anggraeni Nurul Hidajati NURUL HIDAJATI Nurul Hidayati Obing Zaid Sobir Pambudi, Rizdana Galih Pangestu, Puji Dwi Prabowo, Prayudi Setiawan Putri, Pungky Dilaka Raidar, Usman Raihan, Muhammad Ratih Yuniastri Rinaningsih Rinaningsih Rudiana Agustini Saiyidah Mahtari Samik Samik Satriawan, Muhammad Sofyah, Titik Mardiyanti Solly Aryza Sri Hidayati Syarief Sri Yunita Suraida Salat Subagyo, Arif Imam Sumarni Sumarni Sururi, Ahmad Misbakhus Sutoyo, Suyatno Suyatno Suyatno Suyono Suyono Syafi'ah, Rohmatus Syifaiyah, Robiatusy Taufikurahmah, Titik Theodorus Wiyanto Wibowo Wahono Widodo Widjanarko Widjanarko, Widjanarko Widodo Widodo Woro Setyarsih Yuliani, Nuri Yuliani Yuliaturosida, Eka Yunus Yunus Zakiyah, Imroatuz