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All Journal Alchemy : Journal of Chemistry Jurnal Ilmiah Biosaintropis (Bioscience-Tropic) Jurnal Biotek Jurnal Pengabdian Pada Masyarakat Jurnal Medika Nusantara Jurnal Kesehatan dan Kedokteran Jurnal Kesehatan Republik Indonesia Vitamin: Jurnal Ilmu Kesehatan Umum Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Candra Junaedi
Universitas Mathla’ul Anwar
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Antibakteri Staphylococcus Aureus dari Sediaan Sabun Mandi Probiotik Kombucha Bunga Telang (Clitoria Ternatea L) Sebagai Produk Bioteknologi Firman Rezaldi; Candra Junaedi; Retna Yulrosly Ningtias; Fernanda Desmak Pertiwi; Heny Sasmita; Ucu Wandi Somantri; Muhammad Faizal Fathurrohim
Jurnal Biotek Vol 10 No 1 (2022): JUNI
Publisher : Department of Biology Education of Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jb.v10i1.27027

Abstract

The fermented kombucha flower telang (Clitoria ternatea L) is a functional probiotic drink with antibacterial properties. This study aimed to determine and test the antibacterial activity against S. aureus from the formulation of probiotic bath soap preparations fermented kombucha flower telang. This research method was carried out experimentally in an in vitro laboratory. The formulation of probiotic bath soap preparations fermented kombucha flower telang was made with varying concentrations of 20%, 30%, and 40%. The test for antibacterial activity against S. aureus bacteria used the disc diffusion method. The working procedure includes making bath soap preparations and testing the antibacterial activity of the probiotic bath soap preparations fermented kombucha telang flower. The results showed that fermented telang flower kombucha in bath soap had an overall antibacterial activity against S. aureus. The concentration of 40% was the highest in the probiotic bath soap preparations fermented kombucha telang flower with an average inhibition zone diameter of 15.5 mm. The average value of the diameter of the inhibition zone was in a strong category.
ANTI-BACTERIAL EFFECTIVENESS OF Staphylococcus aureus FROM LIQUID SOAP PREPARATION FROM BELUNTAS LEAF ETHANOL EXTRACT (Pluchea indica L) Candra Junaedi; Vicky Herdiny Hasyim; Nia Marlina
Jurnal Ilmiah Biosaintropis (Bioscience -Tropic) Vol 8 No 1 (2022): Agustus 2022
Publisher : Fakultas Matematika & Ilmu Pengetahuan Alam - Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (416.04 KB) | DOI: 10.33474/e-jbst.v8i1.495

Abstract

Beluntas leaves (Pluchea indica L.) is one of the plants that contain compounds such as flavonoids, alkaloids, tannins and saponins. This compound can be used to inhibit the growth of Staphylococcus aureus bacteria. The aim of this research is to make liquid bath soap preparation from ethanol extract beluntas leaves (Pluchea indica L.) and to know anthibactery activity against Staphylococcus aureus bacteria. The formula used in making liquid soap ethanol extract beluntas leaves (Pluchea indica L.) made with variation concentration 0%, 3%, 6% and 9%. The activity of extract of liquid soap beluntas leaves against the bacteria staphylococcus aureus by diffusion method using a concentration variation of 0%, 3%, 6% and 9% having the diameter of the inhibition zone respectively 4,48 mm, 6,23 mm and 7,3 mm. Statistical tests using parametic SPSS tests were carried out, the results obtained at concentrations of 6% and 9% had te same diameter inhibition zone, which was included in the category of moderate inhibition zone.
Karakterisasi Fraksi Aktif Antioksidan dari Biji Gandaria (Bouea macrophylla) Maidah Nopiana; Erica Mutiara Putri; Annastaya Novariyan; Iip Pahrudin; Candra Junaedi; Tarso Rudiana
ALCHEMY:Journal of Chemistry Vol 11, No 1 (2023): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v11i1.17711

Abstract

Gandaria (Bouea macrophylla) plants contain antioxidant compounds that can reduce free radicals. Free radicals are one of the causes of various degenerative diseases. The purpose of this study was to determine the fraction that had the highest antioxidant activity, and to determine the secondary metabolites contained in the most active fraction of B. macrophylla seeds based on LCMS/MS analysis. Maceration of B. macrophylla seeds with ethanol solvent. Ethanol maserate was concentrated and fractionated by liquid-liquid extraction method using n-hexane, ethyl acetate and ethanol as solvents. Antioxidant activity was measured by the free radical scavenger method with 1,1-diphenyl-2-picrylhidrazil as a source of radicals and characterization of the secondary metabolites contained in the most active fraction using a Liquid Chromatography-Mass Spectrometer. B. macrophylla seed ethanol extract has a % yield of 31.75%. The ethyl acetate fraction of B. macrophylla seeds has the highest mass compared to other fractions and has strong antioxidant activity with an IC50 value of 2.95 ppm. The ethyl acetate fraction of B. macrophylla seeds contains tannins, phenolic, flavonoid dan alkaloid compounds. Based on the results of the identification of secondary metabolites by LC-MS/MS, the ethyl acetate fractions of B. macrophylla seeds contained phenylalalnine compounds.
Penyuluhan DAGUSIBU Obat Sebagai Upaya Peningkatan Pengetahuan Masyarakat di Desa Kutakarang – Cibitung, Kabupaten Pandeglang Eka Yulli Kartika; Arini Khaerunnisa; Dhyneu Dwi Jayanti; Eneng Elda Ernawati; Candra Junaedi; Dimas Danang Indriatmoko; Tarso Rudiana; Cory Novi; Agus Setiawan; Dwi Marwati Juli Siswanti; Gina Siti Nurhayati; Hadi Susilo; Swastika Oktavia
Jurnal Pengabdian Pada Masyarakat Vol 8 No 4 (2023): Jurnal Pengabdian Pada Masyarakat
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/jppm.v8i4.662

Abstract

Swamedikasi (pengobatan sendiri) meningkat dikalangan masyarakat, tidak terkecuali masyarakat di Desa Kutakarang, Cibitung Kabupaten Pandeglang. Hal ini perlu diimbangi dengan pengetahuan cara mengelola obat dengan baik dan benar agarr obat dapat memberikan efek terapeutik yang diharapkan dan menghindari kesalahan dalam penggunaan dan pengelolaan obat. DAGUSIBU adalah dapat, guna, simpan dan buang obat dengan benar merupakan salah satu upaya peningkatan penggunaan obat bagi masyarakat yang diselenggarakan melalui kegiatan pelayanan kesehatan oleh tenaga kefarmasian. Pelayanan kesehatan yang dapat diberikan tenaga kefarmasian kepada masyarakat yakni kegiatan pemberian informasi tentang penggunaan dan penyimpanan sediaan farmasi dan alat kesehatan. Tujuan pengabdian ini adalah peningkatan pengetahuan masyarakat dalam memahami cara mendapatkan, menggunakan, menyimpan dan membuang obat, serta memahami cara mengkonsumsi obat dengan baik dan benar. Metode yang digunakan adalah presentasi dan penyulihan. Peserta kegiatan sosialisasi tentang DAGUSIBU berjumlah 54 peserta. Para peserta yang hadir sangat antusias dalam mendengarkan penjelasan dan aktif bertanya terkait penggunaan obat dan penanganannya. Harapan setelah Pengabdian kepada Masyarakat ini, yaitu peserta dapat lebih memahami dalam mengkonsumsi dan mengelola obat dengan baik dan benar. Self-medication is increasing among the community, including the people in Kutakarang Village, Cibitung, Pandeglang Regency. This needs to be balanced with knowledge of how to administer drugs properly and correctly so that drugs can provide the expected therapeutic effect and avoid errors in drug use and management. DAGUSIBU is getting, using, storing and disposing of drugs properly is one of the efforts to increase the use of drugs for the community which is organized through health service activities by pharmacists. Health services that can be provided by pharmacists to the community are the activities of providing information about the use and storage of pharmaceutical preparations and medical devices. The purpose of this service was to increase public knowledge in understanding how to obtain, use, store and dispose of drugs, and understand how to take drugs properly and correctly. The method used is presentation and lecture. Socialization activities about DAGUSIBU went well. There were 54 participants in this activity. The participants who attended were very enthusiastic in listening to explanations and actively asked questions regarding the use of drugs and their treatment. The hope after this Community Service is that participants can have a better understanding of consuming and managing drugs properly and correctly.
FORMULASI DAN UJI AKTIVITAS SEDIAAN KRIM EKSTRAK ETANOL DAUN KELOR (Moringa oleifera Lamk.) SEBAGAI PENGHAMBAT PERTUMBUHAN BAKTERI Propionibacterium acnes Sri Resti Rahayu; Candra Junaedi; Mu'jijah
Jurnal Kesehatan dan Kedokteran Vol. 1 No. 3 (2022): Oktober: Jurnal Kesehatan dan Kedokteran
Publisher : Asosiasi Dosen Muda Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56127/jukeke.v1i3.282

Abstract

Propionibacterium acnes adalah salah satu bakteri penyebab jerawat yang termasuk golongan bakteri gram positif anaerob. Daun kelor dilaporkan mengandung glikosida, flavonoid, dan tanin yang berkhasiat sebagai antibakteri. Tujuan dari penelitian ini adalah untuk mengetahui apakah ekstrak etanol daun kelor dapat diformulasikan menjadi sediaan krim dan berapa konsentrasi yang efektif untuk menghambat pertumbuhan P.acnes. Ekstraksi dilakukan dengan metode maserasi menggunakan etanol 70%. Pengujian aktivitas antibakteri dilakukan dengan menggunakan metode difusi agar dengan cara sumuran. Uji aktivitas krim antibakteri dianalisis dengan metode One Way Anova dilanjutkan uji Tukey HSD dengan tingkat kepercayaan 95%. Uji aktivitas antibakteri hasil penelitian menunjukkan bahwa terdapat perbedaan yang signifikan pada setiap perlakuan yang diberi ekstrak etanol daun kelor F2 (2,5% =3,06), F3 (5%= 4,76), F4 (7,5%= 6,93). Pada perlakuan kontrol negatif sebesar 0 mm dan kontrol positif 17,31 mm (p= 0,000). Konsentrasi ekstrak yang paling efektif pada F4 (7,5%) dengan zona hambat sebesar 6,93 mm dan termasuk kedalam kategori sedang. Sehingga dapat disimpulkan bahwa ekstrak etanol daun kelor dapat diformulasikan menjadi sediian krim dan efektif sebagai penghambat pertumbuhan bakteri P. acnes.
Analisis Pengelolaan Obat di UPTD Puskesmas Singandaru Kota Serang Banten Candra Junaedi; Hasna Dewi; Mujianto Mujianto
Jurnal Medika Nusantara Vol. 2 No. 2 (2024): Mei : Jurnal Medika Nusantara
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/medika.v2i2.1128

Abstract

Drug management in community health centers is important, especially at the planning and procurement stages. Ineffective drug management impacts health centers both medically and economically. The aim is to determine drug management at the UPTD Puskesmas Singandaru by Permekes No. 74 Tahun 2016 and other relevant literature. Method: Observational research with a cross-sectional design. Primary data was taken through interviews and secondary data from drug management data. The samples used are pharmaceutical supplies. Research instruments include LPLPO, RKO, SBBK, and in-depth interview guide sheets. Data analysis is descriptively guided by Permekes No. 74 Tahun 2016 and other relevant literature. Results: The planning suitability indicator is 93% appropriate, the procurement indicator for the available budget for drug purchasing needs is 65% and the BMHP is 35%, the suitability of demand and receipt of drugs is 38% not yet appropriate (100% standard) because there are empty drugs in the gudang farmasi kabupaten kota, storage and distribution indicators of 100% are relevant, as well as recording and reporting indicators of 100% but reporting for Psychotropics and Narcotics is still managed by the Dinas Kesehatan Kota.
Analisis Rasionalitas Penggunaan Obat Dispepsia Di Puskesmas Pamarayan Candra Junaedi; Sumarlin Sumarlin; Agnes Safitri
Vitamin : Jurnal ilmu Kesehatan Umum Vol. 1 No. 4 (2023): October : Jurnal ilmu Kesehatan Umum
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/vitamin.v1i4.349

Abstract

Dyspepsia includes a collection of clinical symptoms consisting of discomfort or persistent (episodic) or recurrence in the upper abdomen. Dyspepsia can be influenced by several factors, including increased gastric acid secretion, diet, and environmental factors, as well as psychological factors such as stress. This research aims to determine the use of dyspepsia medication at the Puskesmas Pamarayan. The type of research used in this research is descriptive observational with a purposive sampling method. The population in this study was 230 dyspepsia patients who visited the Puskesmas Pamarayan. The sample in this study was 31 respondents who had been determined using the Slovin formula with an error tolerance limit of 5%. Data were analyzed descriptively using rationality guidelines which include correct diagnosis, correct drug selection, correct dose, correct time interval, alertness to side effects, and correct information. The results of the study showed that the treatment of dyspepsia at the Puskesmas Pamarayan was rational.
Formulasi Dan Evaluasi Fisik Sediaan Tablet Allopurinol 100 Mg Menggunakan Pati Beras Merah (Oryza Nivara) Sebagai Bahan Pengikat Dengan Metode Granulasi Basah Siti Hujatul Hasanah; Agus Setiawan; Lucky Dita Agustiansyah; Dimas Danang Indriatmoko; Candra Junaedi
Jurnal Kesehatan Republik Indonesia Vol 2 No 9 (2025): JKRI - Agustus 2025
Publisher : PT. INOVASI TEKNOLOGI KOMPUTER

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Beras merah (Oryza nivara) umumnya hanya dikenal sebagai bahan pangan pokok. Padahal, beras ini mengandung komponen pati, yang terdiri atas amilosa dan amilopektin, dan berpotensi dimanfaatkan sebagai bahan pengikat dalam pembuatan tablet. Penelitian ini bertujuan mengevaluasi pengaruh penggunaan pati dari beras merah terhadap karakteristik fisik tablet allopurinol yang dibuat menggunakan metode granulasi basah. Penelitian ini bersifat eksperimental dengan empat variasi formula: satu formula menggunakan pengikat sintetis, sedangkan tiga lainnya memakai pati beras merah dengan konsentrasi berbeda. Formula 0 menggunakan PVP 8%, sementara Formula I, II, dan III masing-masing mengandung pati beras merah sebesar 8%, 12%, dan 16%. Evaluasi sifat fisik tablet menunjukkan bahwa penggunaan pati beras merah menghasilkan tablet dengan bobot dan ukuran yang seragam, kekerasan dalam rentang 4–8 kg, waktu hancur di bawah 15 menit, serta tingkat kerapuhan antara 0,5–1%. Analisis ANOVA menghasilkan nilai signifikansi p = 0,001, yang menunjukkan adanya perbedaan bermakna antar formula. Temuan ini mengindikasikan bahwa variasi konsentrasi pati beras merah memberikan pengaruh terhadap karakteristik fisik tablet allopurinol.
Rasionalitas Penggunaan Oains pada Pasien Osteoarthritis di Klinik Teluk Banten Candra Junaedi; Santi Endrawati; Dimas Danang Indriatmoko; Muhamad Parci
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 2 (2025): March: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i2.1163

Abstract

Osteoarthritis is a type of arthritis that occurs in the area around the joints because the cartilage that protects the ends of the bones begins to break down accompanied by reactive changes at the edges of the joints which can cause pain and difficulty moving. Drug use is said to be rational if the patient receives treatment that is in accordance with clinical needs, namely correct diagnosis, correct drug selection, correct indication, correct dose, correct method of administration, and correct patient. This research aims to use a descriptive analysis design for observational research. The research design used was quantitative research to determine the rationality of using NSAIDs anti-pain medication in osteoarthritis patients undergoing treatment at the Klinik Teluk Banten. The rationality results in this research are, 100% correct diagnosis, 100% correct indication. 100% correct choice of drug, 89% correct dose, 100% correct method of administration, 94% correct patient for Osteoarthritis at Klinik Teluk Banten.
Co-Authors Agnes Safitri Agnes Safitri Agus Setiawan AGUS SETIAWAN Annastaya Novariyan Arini Khaerunnisa Cory Novi Dhyneu Dwi Jayantie Dimas Danang Indriatmoko Dimas Danang Indriatmoko Dwi Marwati Juli Siswanti Eka Yulli Kartika Eneng Elda Ernawati Erica Mutiara Putri Fernanda Desmak Pertiwi Firman Rezaldi Gina Siti Nurhayati Hadi Susilo Hasna Dewi Iip Pahrudin Lucky Dita Agustiansyah Maidah Nopiana Mu'jijah Muhamad Parci Muhammad Faizal Fathurrohim Nia Marlina Retna Yulrosly Ningtias Santi Endrawati Sasmita, Heny Siti Hujatul Hasanah Sri Resti Rahayu Sumarlin Sumarlin Sumarlin Sumarlin Swastika Oktavia Tarso Rudiana, Tarso Ucu Wandi Somantri Vicky Herdiny Hasyim