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All Journal Alchemy : Journal of Chemistry Jurnal Ilmiah Biosaintropis (Bioscience-Tropic) JFL : Jurnal Farmasi Lampung Jurnal Biotek Jurnal IPTEK Bagi Masyarakat Journal of Health and Nutrition Research Jurnal Pengabdian Masyarakat Nusantara Jurnal Pengabdian Pada Masyarakat Jurnal Medika Nusantara Jurnal Kesehatan dan Kedokteran Jurnal Kesehatan Republik Indonesia Vitamin: Jurnal Ilmu Kesehatan Umum Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Journal of Chemistry Sciences and Education Jurnal Pengabdian Ilmu Kesehatan
Candra Junaedi
Universitas Mathla'ul Anwar Banten
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Antibakteri Staphylococcus Aureus dari Sediaan Sabun Mandi Probiotik Kombucha Bunga Telang (Clitoria Ternatea L) Sebagai Produk Bioteknologi Firman Rezaldi; Candra Junaedi; Retna Yulrosly Ningtias; Fernanda Desmak Pertiwi; Heny Sasmita; Ucu Wandi Somantri; Muhammad Faizal Fathurrohim
Jurnal Biotek Vol 10 No 1 (2022): JUNI
Publisher : Department of Biology Education of Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jb.v10i1.27027

Abstract

The fermented kombucha flower telang (Clitoria ternatea L) is a functional probiotic drink with antibacterial properties. This study aimed to determine and test the antibacterial activity against S. aureus from the formulation of probiotic bath soap preparations fermented kombucha flower telang. This research method was carried out experimentally in an in vitro laboratory. The formulation of probiotic bath soap preparations fermented kombucha flower telang was made with varying concentrations of 20%, 30%, and 40%. The test for antibacterial activity against S. aureus bacteria used the disc diffusion method. The working procedure includes making bath soap preparations and testing the antibacterial activity of the probiotic bath soap preparations fermented kombucha telang flower. The results showed that fermented telang flower kombucha in bath soap had an overall antibacterial activity against S. aureus. The concentration of 40% was the highest in the probiotic bath soap preparations fermented kombucha telang flower with an average inhibition zone diameter of 15.5 mm. The average value of the diameter of the inhibition zone was in a strong category.
ANTI-BACTERIAL EFFECTIVENESS OF Staphylococcus aureus FROM LIQUID SOAP PREPARATION FROM BELUNTAS LEAF ETHANOL EXTRACT (Pluchea indica L) Candra Junaedi; Vicky Herdiny Hasyim; Nia Marlina
Jurnal Ilmiah Biosaintropis (Bioscience -Tropic) Vol 8 No 1 (2022): Agustus 2022
Publisher : Fakultas Matematika & Ilmu Pengetahuan Alam - Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (416.04 KB) | DOI: 10.33474/e-jbst.v8i1.495

Abstract

Beluntas leaves (Pluchea indica L.) is one of the plants that contain compounds such as flavonoids, alkaloids, tannins and saponins. This compound can be used to inhibit the growth of Staphylococcus aureus bacteria. The aim of this research is to make liquid bath soap preparation from ethanol extract beluntas leaves (Pluchea indica L.) and to know anthibactery activity against Staphylococcus aureus bacteria. The formula used in making liquid soap ethanol extract beluntas leaves (Pluchea indica L.) made with variation concentration 0%, 3%, 6% and 9%. The activity of extract of liquid soap beluntas leaves against the bacteria staphylococcus aureus by diffusion method using a concentration variation of 0%, 3%, 6% and 9% having the diameter of the inhibition zone respectively 4,48 mm, 6,23 mm and 7,3 mm. Statistical tests using parametic SPSS tests were carried out, the results obtained at concentrations of 6% and 9% had te same diameter inhibition zone, which was included in the category of moderate inhibition zone.
Karakterisasi Fraksi Aktif Antioksidan dari Biji Gandaria (Bouea macrophylla) Maidah Nopiana; Erica Mutiara Putri; Annastaya Novariyan; Iip Pahrudin; Candra Junaedi; Tarso Rudiana
ALCHEMY:Journal of Chemistry Vol 11, No 1 (2023): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v11i1.17711

Abstract

Gandaria (Bouea macrophylla) plants contain antioxidant compounds that can reduce free radicals. Free radicals are one of the causes of various degenerative diseases. The purpose of this study was to determine the fraction that had the highest antioxidant activity, and to determine the secondary metabolites contained in the most active fraction of B. macrophylla seeds based on LCMS/MS analysis. Maceration of B. macrophylla seeds with ethanol solvent. Ethanol maserate was concentrated and fractionated by liquid-liquid extraction method using n-hexane, ethyl acetate and ethanol as solvents. Antioxidant activity was measured by the free radical scavenger method with 1,1-diphenyl-2-picrylhidrazil as a source of radicals and characterization of the secondary metabolites contained in the most active fraction using a Liquid Chromatography-Mass Spectrometer. B. macrophylla seed ethanol extract has a % yield of 31.75%. The ethyl acetate fraction of B. macrophylla seeds has the highest mass compared to other fractions and has strong antioxidant activity with an IC50 value of 2.95 ppm. The ethyl acetate fraction of B. macrophylla seeds contains tannins, phenolic, flavonoid dan alkaloid compounds. Based on the results of the identification of secondary metabolites by LC-MS/MS, the ethyl acetate fractions of B. macrophylla seeds contained phenylalalnine compounds.
Penyuluhan DAGUSIBU Obat Sebagai Upaya Peningkatan Pengetahuan Masyarakat di Desa Kutakarang – Cibitung, Kabupaten Pandeglang Eka Yulli Kartika; Arini Khaerunnisa; Dhyneu Dwi Jayanti; Eneng Elda Ernawati; Candra Junaedi; Dimas Danang Indriatmoko; Tarso Rudiana; Cory Novi; Agus Setiawan; Dwi Marwati Juli Siswanti; Gina Siti Nurhayati; Hadi Susilo; Swastika Oktavia
Jurnal Pengabdian Pada Masyarakat Vol 8 No 4 (2023): Jurnal Pengabdian Pada Masyarakat
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/jppm.v8i4.662

Abstract

Swamedikasi (pengobatan sendiri) meningkat dikalangan masyarakat, tidak terkecuali masyarakat di Desa Kutakarang, Cibitung Kabupaten Pandeglang. Hal ini perlu diimbangi dengan pengetahuan cara mengelola obat dengan baik dan benar agarr obat dapat memberikan efek terapeutik yang diharapkan dan menghindari kesalahan dalam penggunaan dan pengelolaan obat. DAGUSIBU adalah dapat, guna, simpan dan buang obat dengan benar merupakan salah satu upaya peningkatan penggunaan obat bagi masyarakat yang diselenggarakan melalui kegiatan pelayanan kesehatan oleh tenaga kefarmasian. Pelayanan kesehatan yang dapat diberikan tenaga kefarmasian kepada masyarakat yakni kegiatan pemberian informasi tentang penggunaan dan penyimpanan sediaan farmasi dan alat kesehatan. Tujuan pengabdian ini adalah peningkatan pengetahuan masyarakat dalam memahami cara mendapatkan, menggunakan, menyimpan dan membuang obat, serta memahami cara mengkonsumsi obat dengan baik dan benar. Metode yang digunakan adalah presentasi dan penyulihan. Peserta kegiatan sosialisasi tentang DAGUSIBU berjumlah 54 peserta. Para peserta yang hadir sangat antusias dalam mendengarkan penjelasan dan aktif bertanya terkait penggunaan obat dan penanganannya. Harapan setelah Pengabdian kepada Masyarakat ini, yaitu peserta dapat lebih memahami dalam mengkonsumsi dan mengelola obat dengan baik dan benar. Self-medication is increasing among the community, including the people in Kutakarang Village, Cibitung, Pandeglang Regency. This needs to be balanced with knowledge of how to administer drugs properly and correctly so that drugs can provide the expected therapeutic effect and avoid errors in drug use and management. DAGUSIBU is getting, using, storing and disposing of drugs properly is one of the efforts to increase the use of drugs for the community which is organized through health service activities by pharmacists. Health services that can be provided by pharmacists to the community are the activities of providing information about the use and storage of pharmaceutical preparations and medical devices. The purpose of this service was to increase public knowledge in understanding how to obtain, use, store and dispose of drugs, and understand how to take drugs properly and correctly. The method used is presentation and lecture. Socialization activities about DAGUSIBU went well. There were 54 participants in this activity. The participants who attended were very enthusiastic in listening to explanations and actively asked questions regarding the use of drugs and their treatment. The hope after this Community Service is that participants can have a better understanding of consuming and managing drugs properly and correctly.
FORMULASI DAN UJI AKTIVITAS SEDIAAN KRIM EKSTRAK ETANOL DAUN KELOR (Moringa oleifera Lamk.) SEBAGAI PENGHAMBAT PERTUMBUHAN BAKTERI Propionibacterium acnes Sri Resti Rahayu; Candra Junaedi; Mu'jijah
Jurnal Kesehatan dan Kedokteran Vol. 1 No. 3 (2022): Oktober: Jurnal Kesehatan dan Kedokteran
Publisher : Asosiasi Dosen Muda Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56127/jukeke.v1i3.282

Abstract

Propionibacterium acnes adalah salah satu bakteri penyebab jerawat yang termasuk golongan bakteri gram positif anaerob. Daun kelor dilaporkan mengandung glikosida, flavonoid, dan tanin yang berkhasiat sebagai antibakteri. Tujuan dari penelitian ini adalah untuk mengetahui apakah ekstrak etanol daun kelor dapat diformulasikan menjadi sediaan krim dan berapa konsentrasi yang efektif untuk menghambat pertumbuhan P.acnes. Ekstraksi dilakukan dengan metode maserasi menggunakan etanol 70%. Pengujian aktivitas antibakteri dilakukan dengan menggunakan metode difusi agar dengan cara sumuran. Uji aktivitas krim antibakteri dianalisis dengan metode One Way Anova dilanjutkan uji Tukey HSD dengan tingkat kepercayaan 95%. Uji aktivitas antibakteri hasil penelitian menunjukkan bahwa terdapat perbedaan yang signifikan pada setiap perlakuan yang diberi ekstrak etanol daun kelor F2 (2,5% =3,06), F3 (5%= 4,76), F4 (7,5%= 6,93). Pada perlakuan kontrol negatif sebesar 0 mm dan kontrol positif 17,31 mm (p= 0,000). Konsentrasi ekstrak yang paling efektif pada F4 (7,5%) dengan zona hambat sebesar 6,93 mm dan termasuk kedalam kategori sedang. Sehingga dapat disimpulkan bahwa ekstrak etanol daun kelor dapat diformulasikan menjadi sediian krim dan efektif sebagai penghambat pertumbuhan bakteri P. acnes.
Potential Pharmaceutical Biotechnology Products in the Form of Formulations and Preparations of Telang Flower Kombucha Dish Soap (Clitoria ternatea L) as an Antibacterial from Beef (Bos taurus) Isolate Firman Rezaldi; Eva Nurvadilah; Candra Junaedi; Ucu Wandi Somantri; M. Fariz Fadillah; Vevi Maritha; Ratna Fitry Yenny; Diyan Yunanto Setyaji
Journal of Health and Nutrition Research Vol. 3 No. 1 (2024)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v3i1.237

Abstract

This research aims to see the potential of each formulation and preparation of dishwashing soap with the active ingredient telang flower kombucha in inhibiting the growth of pathogenic bacteria isolated from beef. This research is a laboratory experiment, namely by making a dishwashing soap base without the active substance of telang flower kombucha. Make a dishwashing soap base that adds the active substance of butterfly pea flower kombucha at concentrations of 20%, 30% and 40%. Biochemical identification results have shown that beef samples contain gram-positive bacteria in the form of Staphylococcus aureus and Listeria monocytogenes, as well as gram-negative bacteria in the form of Salmonella thyposa and Escherichia coli. The results of this research have also proven that pharmaceutical biotechnology products in the form of formulations and dishwashing soap preparations with the active ingredient telang flower kombucha have a positive correlation in inhibiting the growth of the four test bacteria. Based on the one-way ANOVA statistical test at each P value <0.05, it proves that telang flower kombucha dish soap at a concentration of 40% according to post hoc analysis is not significantly different from concentrations of 20% and 30% as a pharmaceutical and antibacterial biotechnology product. isolated from beef. The conclusion of this research is that the formulation and preparation of dishwashing soap at a concentration of 40% proved to be the most effective as a pharmaceutical biotechnology product in inhibiting the growth of the four test bacteria.
Edukasi Golongan Obat Bebas dan Obat Bebas Terbatas Pada Siswa Kelas 12 Di Pandeglang Banten Candra Junaedi; Ucu Mawardi; Dimas Danang Indratmoko
Jurnal Pengabdian Masyarakat Nusantara Vol. 4 No. 3 (2022): September : Jurnal Pengabmas Nusantara
Publisher : Universitas Muhammadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/pengabmas.v4i3.502

Abstract

Public knowledge of drugs is quite limited, especially among teenagers. Adolescence is a developmental change between childhood and adulthood that results in physical, cognitive, and psychosocial changes. The aim of this education is the early introduction of over-the-counter drug classes to teenagers so that awareness is formed regarding the proper and correct use of over-the-counter drugs. The activities were conducted on class 12 students at SMA Mathlaul Anwar Pandeglang Banten. Educational facilities use leaflets that are distributed to activity participants. Evaluation of participants was carried out by asking for answers and filling in pre-test and post-test questions regarding education on the use of over-the-counter drugs. The results of education on the introduction of over-the-counter non-restricted medicines before and after schooling can increase teenagers' knowledge about self-medication over-the-counter drugs, especially adequate information regarding the correct use of drugs, including indications, dosage, method of use, side effects, contraindications, and drug expiration dates.
Analisis Pengelolaan Obat di UPTD Puskesmas Singandaru Kota Serang Banten Candra Junaedi; Hasna Dewi; Mujianto Mujianto
Jurnal Medika Nusantara Vol. 2 No. 2 (2024): Mei : Jurnal Medika Nusantara
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/medika.v2i2.1128

Abstract

Drug management in community health centers is important, especially at the planning and procurement stages. Ineffective drug management impacts health centers both medically and economically. The aim is to determine drug management at the UPTD Puskesmas Singandaru by Permekes No. 74 Tahun 2016 and other relevant literature. Method: Observational research with a cross-sectional design. Primary data was taken through interviews and secondary data from drug management data. The samples used are pharmaceutical supplies. Research instruments include LPLPO, RKO, SBBK, and in-depth interview guide sheets. Data analysis is descriptively guided by Permekes No. 74 Tahun 2016 and other relevant literature. Results: The planning suitability indicator is 93% appropriate, the procurement indicator for the available budget for drug purchasing needs is 65% and the BMHP is 35%, the suitability of demand and receipt of drugs is 38% not yet appropriate (100% standard) because there are empty drugs in the gudang farmasi kabupaten kota, storage and distribution indicators of 100% are relevant, as well as recording and reporting indicators of 100% but reporting for Psychotropics and Narcotics is still managed by the Dinas Kesehatan Kota.
Analisis Rasionalitas Penggunaan Obat Dispepsia Di Puskesmas Pamarayan Candra Junaedi; Sumarlin Sumarlin; Agnes Safitri
Vitamin : Jurnal ilmu Kesehatan Umum Vol. 1 No. 4 (2023): October : Jurnal ilmu Kesehatan Umum
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/vitamin.v1i4.349

Abstract

Dyspepsia includes a collection of clinical symptoms consisting of discomfort or persistent (episodic) or recurrence in the upper abdomen. Dyspepsia can be influenced by several factors, including increased gastric acid secretion, diet, and environmental factors, as well as psychological factors such as stress. This research aims to determine the use of dyspepsia medication at the Puskesmas Pamarayan. The type of research used in this research is descriptive observational with a purposive sampling method. The population in this study was 230 dyspepsia patients who visited the Puskesmas Pamarayan. The sample in this study was 31 respondents who had been determined using the Slovin formula with an error tolerance limit of 5%. Data were analyzed descriptively using rationality guidelines which include correct diagnosis, correct drug selection, correct dose, correct time interval, alertness to side effects, and correct information. The results of the study showed that the treatment of dyspepsia at the Puskesmas Pamarayan was rational.
Peningkatan Pengetahuan Siswa dan Siswi SMA Presiden 2 Tanjung Lesung melalui Pelatihan Pembuatan Sabun Cair Ekstrak Daun Sisik Naga Kartika, Eka Yulli; Oktavia, Swastika; Junaedi, Candra; Indriatmoko, Dimas Danang; Jayantie, Dhyneu Dwi; Ernawati, Eneng Elda; Khaerunnisa, Arini; Suryani, Nani; Nurhayati, Ghina Siti; Siswanti, Dwi Marwati Juli; Novi, Cory; Setiawan, Agus
Jurnal Pengabdian Pada Masyarakat Vol 10 No 2 (2025): Jurnal Pengabdian Pada Masyarakat
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/jppm.v10i2.1033

Abstract

Sabun terbentuk melalui reaksi antara asam lemak dan basa kuat, dan umumnya digunakan sebagai pembersih untuk menghilangkan kotoran pada kulit. Salah satu jenis sabun yang diminati pada saat ini oleh masyarakat yaitu sabun cair. Hal ini dikarenakan penggunaannya yang lebih praktis dan efisien. SMA Presiden 2 Tanjung Lesung merupakan sekolah umum semi militer yang memiliki 2 bidang ilmu yaitu IPA dan IPS. Kegiatan ini bertujuan untuk memberikan pengetahuan dan keterampilan kepada siswa/i SMA Presiden 2 Tanjung Lesung tentang pengaplikasian ilmu dan tekonologi dalam menghasilkan sabun mandi. Metode kegiatan yang dilakukan berupa pemaparan materi dan pelatihan pembuatan sabun cair dengan campuran ekstrak daun sisik naga (bahan alam) serta memberikan kuisioner berupa pretest dan postest untuk mengetahui pengaruhnya kepada siswa/i. Hasilnya didapatkan bahwa terdapat peningkatan pengetahuan dari kegiatan pengabdian kepada masyarakat (PKM) dari nilai rata-rata prestest 70,23 menjadi 86,28 untuk nilai posttest. Soap is formed through a reaction between fatty acids and a strong base and is commonly used as a cleanser to remove dirt from the skin. One type of soap that is currently popular among the public is liquid soap due to its practical and efficient use. SMA Presiden 2 Tanjung Lesung is a semi-military public school that offers two fields of study: Science and Social Studies. This activity aims to provide knowledge and skills to the students of SMA Presiden 2 Tanjung Lesung on the application of science and technology in producing bath soap. The methods used in this activity include material presentation, hands-on training in making liquid soap with dragon scale leaf extract (a natural ingredient), and pretest and post-test to measure the impact. The results showed an increase in knowledge from this community service activity, with the average pretest score rising from 70.23 to an average post-test score of 86.28.
Co-Authors Abillah, Syamsudin Agnes Safitri Agnes Safitri AGUS SETIAWAN Agus Setiawan Annastaya Novariyan Arini Khaerunnisa Arini Khaerunnisa Baha Udin Cory Novi Deni Nelissa Dhyneu Dwi Jayantie Dimas Danang Indratmoko Dimas Danang Indriatmoko Dimas Danang Indriatmoko Dini Afriani Khasanah Ditta Ahmad Herviana Diyan Yunanto Setyaji Dwi Marwati Juli Siswanti Eka Yulli Kartika Eneng Elda Ernawati Eneng Elda Ernawati Erica Mutiara Putri Eva Nurvadilah Fachrudin Perdana Fajrin Noviyanto Fernanda Desmak Pertiwi Frida Elasjulia Gina Siti Nurhayati Hadi Susilo Hasna Dewi Iip Pahrudin Indriatmoko, Dimas Danang Irwan Irwan Irwanto Irwanto Ivan Wagner Jayantie, Dhyneu Dwi Kartika, Eka Yulli Listya Triandari Lucky Dita Agustiansyah M. Fariz Fadillah M. Fariz Fadillah Mardianto Maidah Nopiana Maritha, Vevi Miftahul Nur &#039;Amaliyah Mu'jijah Muhamad Ichsan Fahlevy Muhamad Parci Muhammad Faizal Fathurrohim Nani Suryani Nia Marlina Nur Thooyibah Nurhayati, Ghina Siti Nurhayati, Nina Nurvadilah, Eva Ratna Fitry Yenny Retna Yulrosly Ningtias Santi Endrawati Sari, Ratna Permana Sartika, Nenden Suciyati Sasmita, Heny Setyaji, Diyan Yunanto Siswanti, Dwi Marwati Juli Siti Hujatul Hasanah Sri Resti Rahayu Stiani, Sofi Nurmay Sumarlin Sumarlin Sumarlin Sumarlin Sumarlin US Swastika Oktavia Tarso Rudiana, Tarso Tuti Rostianti Maulani Ucu Mawardi Ucu Wandi Somantri Vevi Maritha Vicky Herdiny Hasyim Widiya Putri Yenny, Ratna Fitry Yusi Anggriani Yusransyah, Yusransyah