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All Journal AL KAUNIYAH Jurnal Teknosains Indonesian Journal of Pharmaceutical Science and Technology Majalah Obat Tradisional JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Kimia Riset Chemistry Indonesian Journal of Chemical Research Al-Khidmah PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Acta Chimica Asiana Indonesian Journal of Pharmaceutical and Clinical Research Jurnal Insan Farmasi Indonesia Jurnal Farmasi Komunitas Media Farmasi Indonesia Jurnal Farmasi Sains dan Praktis Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Borneo Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Journal of Tropical Pharmacy and Chemistry Jurnal Sains dan Kesehatan Journal Pharmacy of Tanjungpura Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan
Bambang WIJIANTO
Universitas Tanjungpura
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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The Effectiveness Assay of Healing Incutions of Nanostructured Lipid Carriers (NLCS) Ethanol Extract of Moringa Leaf (Moringa oleifera) on White Rats (Rattus norvegicus) Bambang Wijianto; Liza Pratiwi
Al-Kauniyah: Jurnal Biologi Vol. 19 No. 2 (2026): AL-KAUNIYAH: JURNAL BIOLOGI
Publisher : Department of Biology, Faculty of Science and Technology, Syarif Hidayatullah State Islami

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/kauniyah.v19i2.43051

Abstract

Wounds are disruptions of tissue integrity that impair normal physiological function. Nanostructured Lipid Carriers (NLCs) are lipid-based nanosystems that enhance the delivery of bioactive compounds. Moringa oleifera leaves contain bioactive constituents, including isothiocyanates and cytokinins (zeatin), which exhibit antibacterial activity and promote cell proliferation, potentially accelerating wound healing. This study aimed to evaluate the wound-healing effectiveness of NLCs containing Moringa oleifera leaf ethanol extract. An acute open-incision wound model was established in rats, divided into five groups: normal control, betadine ointment (positive control), NLC base (negative control), extract gel, and NLCs containing 5% Moringa oleifera leaf ethanol extract. Treatments were applied topically, and wound healing was monitored by measuring wound area reduction with ImageJ. The percentage of wound closure and area under the curve (AUC) values were calculated and analyzed using one-way ANOVA. Both the extract gel and NLC formulations accelerated wound healing compared with the positive and negative controls. Complete wound closure was achieved on day 8 in the treatment groups, whereas the positive and negative controls reached complete closure on days 10 and 14, respectively. These findings indicate that NLCs containing Moringa oleifera leaf ethanol extract have potential as an effective topical formulation for promoting wound healing.
UJI ANTIOKSIDAN EKSTRAK METANOL SIPUT ONCHIDIID (Onchidium typhae) DENGAN METODE DPPH Guci Intan Kemuning; Bambang Wijianto; Andhi Fahrurroji
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 2 No. 1 (2023): Januari : Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v2i1.794

Abstract

Siput Onchidid (Onchidium typhae) merupakan spesies dalam kelas gastropoda yang dapat ditemukan di daerah pesisir pulau Buton dan juga Madura dan Kalimantan Barat.. Siput onchidid diketahui memiliki kandungan metabolit sekunder berupa steroid yang dapat berpotensi sebagai antioksdian. Penelitian ini membahas tentang uji antioksidan di dalam siput onchidid dengan metode DPPH (1,1- diphenil-2-pikrilhirazil) dengan menggunakan pelarut methanol dan pengujian skrining senyawa metabolik ekstrak dengan uji fitokimia pada ekstrak yang meliputi uji steroid, alkaloid, dan steroid. Hasil pengujian didapat bahwa ekstrak metanol siput onchidid memiliki terdapat senyawa metabolik sekunder dari golongan alkaloid dan steroid yang ditandai dengan reaksi positif. Hasil uji antioksidan dengan metode DPPH dengan senyawa pembanding vitamin C. Penelitian menunjukkan besar aktivitas antioksidan ekstrak metanol siput onchidid yang dinyatakan dengan nilai IC50 sebesar 92,045 yang dikategorikan antioksidan kategori kuat.
Pemberdayaan Siswa SMK Bina Dharma Melalui Pembuatan Serbuk Effervescent sebagai Produk Kesehatan Berbasis Etnofarmasi: Empowering Bina Dharma Vocational School Students Through the Production of Effervescent Powder as an Etnopharmacy-Based Health Product Liza Pratiwi; Bambang Wijianto; Muhammad Akib Yuswar; Muhammad Nur Ajwad; Fakhruddin Fakhruddin
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 11 No. 5 (2026): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v11i5.11413

Abstract

Vocational education that combines theory and practice has been proven to be effective in improving students' skills, particularly in preparing them for the challenges of the working world. This study aims to evaluate the effectiveness of the materials and practices used in the production of effervescent moringa powder on students' understanding at SMK Bina Dharma Pratama. The research design used was quasi-experimental with a one-group pretest-posttest design. The study began with a pre-test to assess students' initial knowledge, followed by the provision of materials and practical training in the production of effervescent moringa powder. After the activities, the students were given a posttest to measure their increased understanding. The study's results showed an average score increase from 53.75 (pre-test) to 63.75 (post-test), or approximately 18.6%. This increase indicates a significant learning gain. Despite variations in student results, this finding suggests that practice-based learning can enhance students' technical skills and conceptual understanding in pharmacy. This study contributes to the development of educational methods that integrate theory and practice to enhance students' practical skills and to the implementation of experiential education in vocational training.
Design of Robusta Coffee Extract and Kelulut Honey Effervescent Granules with Different Sweeteners Ramadhan, Bayu Rizky; Pratiwi, Liza; Wijianto, Bambang
Indonesian Journal of Pharmaceutical Science and Technology Vol 13, No 2 (2026)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v13i2.67405

Abstract

The primary challenge in pharmaceutical preparation is the low stability of most active substances. Effervescent granules serve as a strategic solution, enhancing the chemical stability of robusta coffee (Coffea canephora) and kelulut honey (Heterotrigona itama) while providing rapid solubility and masking unpleasant tastes to improve patient adherence. Robusta coffee beans and kelulut honey are antioxidant-rich. This study created effervescent granules from a 70% ethanol extract of robusta coffee seeds and kelulut honey with stevia, mannitol, and lactose to achieve stable physicochemical properties and to increase the taste acceptability of the preparation. The research had five stages: extraction with 70% ethanol, design using the Simplex Lattice Design method, physicochemical properties evaluation of the optimum formula, real-time physical stability, and DPPH in vitro testing. The optimal formulation had 3.70%:7.29%:9.00% (stevia: mannitol: lactose). The brown mixture tasted sweet-sour and smelled like coffee. Physical evaluations revealed a moisture content of 2.53±0.10%, a pH of 6.16±0.07, and a flow rate of 10.81±0.07 seconds. While the raw extract combination showed an IC50 of 7.707 µg/mL, the optimized granules recorded 33.982 µg/mL, indicating strong antioxidant activity. In conclusion, the formulation successfully provides a stable, fast-dispersing, and palatable delivery system for natural antioxidants, offering significant potential for nutraceutical applications.
UJI ANTIOKSIDAN EKSTRAK METANOL SIPUT ONCHIDIID (Onchidium typhae) DENGAN METODE DPPH Guci Intan Kemuning; Bambang Wijianto; Andhi Fahrurroji
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 2 No. 3 (2022): November : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v2i3.810

Abstract

Siput Onchidid (Onchidium typhae) merupakan spesies dalam kelas gastropoda yang dapat ditemukan di daerah pesisir pulau Buton dan juga Madura dan Kalimantan Barat.. Siput onchidid diketahui memiliki kandungan metabolit sekunder berupa steroid yang dapat berpotensi sebagai antioksdian. Penelitian ini membahas tentang uji antioksidan di dalam siput onchidid dengan metode DPPH (1,1- diphenil-2-pikrilhirazil) dengan menggunakan pelarut methanol dan pengujian skrining senyawa metabolik ekstrak dengan uji fitokimia pada ekstrak yang meliputi uji steroid, alkaloid, dan steroid. Hasil pengujian didapat bahwa ekstrak metanol siput onchidid memiliki terdapat senyawa metabolik sekunder dari golongan alkaloid dan steroid yang ditandai dengan reaksi positif. Hasil uji antioksidan dengan metode DPPH dengan senyawa pembanding vitamin C. Penelitian menunjukkan besar aktivitas antioksidan ekstrak metanol siput onchidid yang dinyatakan dengan nilai IC50 sebesar 92,045 yang dikategorikan antioksidan kategori kuat.
Co-Authors Agus Setyawan Agus Styawan Ajeng, Melia Amirah Mohd Gazzali Ananda, Elcie Andhi FAHRURROJI Andhi Fahrurroji Andhi Fahrurroji Andhi FAHRURROJI Andhi Fahrurroji Andhi Fahrurroji Angellica, Grecya Annisa Larasati Nurhidayah Annisa Larasati Nurhidayah Arief, Ihsahnul Audrey Thendralie Ayu Setyaningrum Azura, Dhea Nur Badaria, Lailatul Buannata, Jordi Budiarto, Dwi Damanik, Virna Helena Dimas Achmad Mu’arif Dwi Nurahmanto Emy OKTAVIANI Evi Umayah Ulfa Fahrauk Faramayuda, Fahrauk Fajar Nugraha Fakhruddin Fakhruddin Fania Mufti Mufidah Guci Intan Kemuning Guci Intan Kemuning Hadi Kurniawan Hafrizal Riza Hamzah, Hasyrul Hariyanto IH Harum Nadyanti Usman Ihsanul Arief Inggrid Aprilia Manullang Intan Yap Irawan, Dandi Isnindar Isnindar Lidya Hafidzah Putri Lina Winarti Liza Pratiwi Luliana, Sri Lurizma Putri Adinda Mohamad Andrie Muhammad Akib Yuswar Muhammad Hilmi Afthoni Muhammad Nur Ajwad Nadine, Shahira Audia Nanda Paramita Nasution, Nuraini Pinondang Simaremare Pinondang Simaremare, Pinondang Putri, Alifa Rapaella Fadia Tito Rafika Sari Ramadhan, Bayu Rizky Randi Mulyana Putra Risa Indriyani Riyadh Aqilsya Amaryl Dyas Riyadh Aqilsya Amaryl Dyas Ropiqa, Meri Shoma Rizkifani Tendianus, Tendianus Utami, Amanda Yanasari Virna Helena Damanik Wijianto, Bambang Wijianto Yanastya, Salsa Yoana Yohana, Vanesha Yuswar, Muhammad Akib Zikri, Tan Muhamad