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Strategizing Antiviral Medication Usage for Chronic Kidney Disease Patients with SARS-CoV-2: Insights from Inpatient Pharmacy Practices at Hospital Settings Yuneka Saristiana; Leny Witaning Kusumati; Neni Probosiwi; Tsamrotul Ilmi; Nur Fahma Laili; Fendy Prasetyawan
Journal Health of Indonesian Vol. 2 No. 02 (2024): Journal Health of Indonesian, Edition July 2024
Publisher : Paspama Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58471/health.v2i02.120

Abstract

The emergence of the SARS-CoV-2 virus in 2020 led to the onset of the COVID-19 pandemic, posing significant challenges globally. As of December 19, 2021, the worldwide confirmed cases surpassed 273 million, with a devastating death toll exceeding 5.3 million. Indonesia reported its first case on March 2, 2020, and has since faced escalating numbers, necessitating urgent attention.Chronic kidney disease (CKD) has emerged as a commonly occurring comorbidity among COVID-19 patients, drawing attention due to the vulnerability of CKD patients to medical complications. Understanding the use of antiviral drugs in CKD patients with COVID-19 is essential, considering the risks of drug toxicity and interactions. This study aims to investigate the frequency of antiviral drug usage in COVID-19 patients with CKD, providing insights into treatment strategies and guiding medical practitioners. Conducted at Dr. Soedomo Trenggalek Regional Hospital, the research utilizes a cross-sectional, non-experimental design and purposive sampling method. Data collection involves patients' medical records, focusing on demographics, antiviral drug usage, disease severity, treatment duration, mortality rates, and potential side effects. The demographic analysis reveals that the majority of COVID-19 patients with CKD are aged 50 and above, with males comprising 74% of the cohort. Age and gender influence disease severity, with older individuals and males at higher risk. Antiviral drug usage predominantly includes favipiravir (64%) and remdesivir (36%), underscoring their importance in treatment protocols. Decisions regarding antiviral therapy in CKD patients with COVID-19 require careful consideration of benefits, risks, and patient characteristics.
Unveiling Pagodroma Nivea's Fossil Healing Power: A Journey Through Farmacoantarctic Chronicles And Bioactivity Studies Yuneka Saristiana; Yunita Dian Permatasari; Anita Dwi Setyarini; Hasriyani, Hasriyani; Neni Probosiwi; Fendy Prasetyawan
Journal Health of Indonesian Vol. 2 No. 02 (2024): Journal Health of Indonesian, Edition July 2024
Publisher : Paspama Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58471/health.v2i02.122

Abstract

Research on the bioactivity of Antarctic organisms has garnered significant attention due to the continent's unique environmental conditions and the potential therapeutic value of its inhabitants. This study delves into the bioactivity of Pagodroma nivea, commonly known as the Snow Petrel, found in Antarctica, aiming to explore its medicinal potential. Despite previous research highlighting the bioactivity of various organisms in extreme environments, specific investigations into Pagodroma nivea remain scarce. Farmacoantarctic Research offers a promising avenue for exploring the therapeutic properties of Antarctic organisms, including Pagodroma nivea, traditionally used for medicinal purposes by local communities. Understanding the biochemical adaptations of organisms to Antarctica's extreme conditions is crucial, as these adaptations may yield bioactive compounds with pharmacological potential. The research not only seeks to uncover the bioactivity of Pagodroma nivea but also aims to contribute to drug development and environmental conservation efforts. In a parallel discussion, the study examines Mumijo, a traditional remedy found in various regions, including Antarctica. Chemical analysis of Mumijo extract, particularly the ester wax fraction, reveals its potential biomedical applications, including wound healing, skin diseases, and neuroprotection. The presence of glycerol-related ethers in Antarctic Mumijo suggests further avenues for exploration in neuroprotection and antimicrobial properties. By investigating the bioactivity of Antarctic organisms like Pagodroma nivea and Mumijo, this research offers insights into their therapeutic potential and underscores the importance of conservation efforts to preserve these unique ecosystems.
Kegiatan Bakti Sosial Di Masyarakat Dalam Upaya Pengenalan Penyakit Sejak Dini ilmi, Tsamrotul; Probosiwi, Neni; Dhafin, Anis Akhwan; Laili, Nur Fahma; Khadir, Mujtahid Bin Abd; Sukmawati, Datin An-Nisa; Yuniarto, Prayoga Fery
Journal Of Human And Education (JAHE) Vol. 4 No. 6 (2024): Journal of Human And Education (JAHE)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jh.v4i6.1797

Abstract

Upaya untuk mendeteksi penyakit pada masyarakat, kegiatan bakti sosial merupakan kegiatan yang akan sangat membantu, dan kegiatan ini dapat meningkatkan kepedulian terhadap kesehatan diri. Pelaksanaan kegiatan Baksos di Desa Jongbiru Kabupaten Kediri bertujuan untuk memberikan pelayanan pemeriksaan dan pengobatan gratis kepada masyarakat. Kemudian memberikan informasi kesehatan yang baik dan benar kepada masyarakat sehingga dapat membentuk persepsi kesehatan yang positif dan pola hidup sehat. Kegiatan ini diikuti oleh 31 orang dengan usia rata-rata 18-67 tahun. Tahapan selama kegiatan berlangsung yaitu: perencanaan dan penyusunan proposal kegiatan. Observasi dan survey lokasi. Sosialisasi dan persiapan kegiatan. Pengumpulan masyarakat desa Jongbiru. Melakukan pemeriksaan kesehatan pada masyarakat. Konsultasi dengan apoteker dan pemberian informasi serta edukasi kepada masyarakat desa Jongbiru. Dengan demikian, Baksos sangat penting dalam mendeteksi penyakit sejak dini, meningkatkan kepedulian masyarakat terhadap kesehatannya, serta menyediakan akses konsultasi dan pemeriksaan kesehatan yang diperlukan. Hal ini penting untuk mencegah penyakit lebih lanjut dan meningkatkan kualitas hidup masyarakat.
EDUKASI TERAPI HIPERTENSI DAN PEMANFAATAN HERBAL JUS UNTUK TERAPI ALTERNATIF: EDUKASI TERAPI HIPERTENSI DAN PEMANFAATAN HERBAL JUS UNTUK TERAPI ALTERNATIF Probosiwi, Neni; Ilmi, Tsamrotul; Laili, Nur Fahma; Bin Abd Kadir, Mujtahid
Jurnal Abdi Masyarakat Vol. 6 No. 2 (2023): Jurnal Abdi Masyarakat Mei 2023
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30737/jaim.v6i2.4542

Abstract

Hipertensi merupakan penyakit tidak menular yang prevalensinya mengalami peningkatan. Hipertensi adalah keadaan dimana pada tekanan sistolik darah > 140mmHg sedangkan pada tekanan diastolik darah >90mmHg yang dilakukan pemeriksaan berulang. Prinsip penatalaksanaan terapi untuk hipertensi yaitu terapi farmakologi dan nonfarmakologi. Salah satu terapi nonfarmakologi yaitu pemanfaatan herbal jus untuk terapi alternatif menurunkan tekanan darah pada penderita hipertensi. Tujuan edukasi terapi hipertensi dan pemanfaatan herbal jus ini untuk menurunkan tekanan darah pada penderita hipertensi dan melatih masyarakat untuk menurunkan tekanan darah melalui pembuatan herbal jus secara mandiri di rumah. Bahan yang digunakan untuk pembuatan herbal jus meliputi : buah melon, brokoli hijau, blimbing wuluh, jahe, serai dan madu. Kegiatan yang dilakukan meliputi pemberian edukasi melalui pembagian leaflet yang berisi definisi, klasifikasi, penyebab serta penatalaksanaan farmakologi dan nonfarmakologi berupa terapi komplementer sebagai upaya mengatasi hipertensi dan mencegah komplikasi hipertensi dan demosntrasi pemanfaatan herbal jus untuk terapi alternatif hipertensi. Jumlah peserta kegiatan ini 25 orang. Kegiatan ini dimulai dengan pembukaan, pemberian edukasi melalui pembagian leaflet, demontrasi pembuatan jus herbal, tanya jawab dan feedback dari peserta. Masyarakat tampak antusias dan mampu mempraktikkan membuat jus herbal. Kegiatan tentang demonstrasi terapi nonfarmakologi untuk menurunkan tekanan darah dapat dilaksanakan rutin dirumah dengan alat dan bahan yang mudah di dapatkan.
PENYULUHAN PENGGUNAAN OBAT OVER THE COUNTER (OTC) DI KELURAHAN NGAMPEL KOTA KEDIRI Siswidiasari, Arifani; Charliandri Saputra Wahab; Prayoga Feri Yuniarto; Probosiwi, Neni
Jurnal Abdi Masyarakat Vol. 7 No. 1 (2023): Jurnal Abdi Masyarakat November 2023
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30737/jaim.v7i1.5002

Abstract

Self-medication is a medication process based on complaints or symptoms up to the drug selection stage by themselves. Percentage of self-medication behavior in Kediri City increases every year so information about self-medication is needed. The class of drugs that can be used for self-medication are over the counter (OTC) drugs which are a class of over-the-counter drugs and limited over-the-counter drugs. These drugs can be purchased without a doctor's prescription, safe and effective if used according to the instructions for use. This activity aims to change the mindset and perspective of the community to be able to respond appropriately to how to use drugs by themselves. Community service activities in the form of counseling using the lecture method combined with a question and answer session, completed the pretest and posttest questionnaires, and last session is the distribution of leaflets regarding the use of OTC drugs. The target of the activity is the community in the Ngampel Village, Kediri City. There was an increase in knowledge about the use of OTC drugs in the community in Ngampel Village, Kediri City after being given counseling. We hope that after participating in counseling, people's knowledge will increase in using OTC drugs properly.
Factors Affecting the Retention Value of Drug Addict Patients in Methadone Maintenance Therapy Siswidiasari, Arifani; Neni Probosiwi; Nur Fahma Laili; Tsamrotul Ilmi; Prayoga Ferry Yuniarto; Anak Agung Indah Krisnadewi; Oktaviarika Dewi H
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 5 (2024): March 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i5.8665

Abstract

Methadone is a synthetic drug belonging to the opiate class that is given in oral dosage form to patients as a substitute therapy for opioid addiction. Methadone was chosen as the main substitution therapy because it has an effect resembling morphine and cocaine with a longer working life so that it can be given once a day which is used by drinking. This study aims to determine the factors that affect the retention value of drug addict patients in methadone maintenance therapy at Bangil Health Center. This study was conducted retrospectively, taking medical record data of patients who followed methadone maintenance therapy selected by consecutive sampling. Data obtained as many as 35 patients. The results of demographic data showed the most male sex 33 people (94.3%), aged 26-35 years 22 (62.9%), SMA 29 (82.9%), working 35 (100%), married 27 (77.1%), opium 35 (100%), amphetamines 26 (74.29%), alcohol 33 (94.29%) and tobacco 33 (94.29%). The highest initial dose was 30-50mg, 23 people (65.7%), the smallest maintenance dose <60mg, 33 people (94.3%) and the largest maintenance dose >120mg, 24 people (68.6%). The retention value of patients < 6 months is 7 people (20%) and > 6 months 28 people (80%)
The Relationship between Diabetes Self-Management Education and Health-Related Quality of Life (HRQoL) among Patients with Type 2 Diabetes Mellitus Probosiwi, Neni; Siswidiasari, Arifani
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 11 (2024): September 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i11.11578

Abstract

Diabetes Mellitus (DM) is a chronic metabolic condition marked by elevated blood glucose levels, leading to damage in critical organs. This study aimed to evaluate the relationship between diabetes self-management education (DSME) and health-related quality of life (HRQoL) in type 2 diabetes patients at the Balerejo Community Health Center. A prospective cross-sectional study was conducted, collecting data from 50 patients using consecutive sampling and analyzed through the Chi-Square test. The demographic profile showed that 60% of participants were female, 60% were aged 36-45, and 56% had a normal BMI. Most patients had good dietary management (64%) but poor physical exercise habits (84%). HRQoL results indicated that 64% scored high in physical functioning, with other domains such as vitality (56%) and social functioning (56%) also showing positive outcomes. A significant relationship was found between DSME and HRQoL, with a P-value of 0.002 and an odds ratio of 7.2. These findings underscore the crucial role of DSME in enhancing the quality of life for type 2 diabetes patients by promoting better disease management practices.
EDUKASI PEMANFAATAN TANAMAN HERBAL UNTUK ANTIDIABETES PADA MASYARAKAT DI DESA SELOSARI KABUPATEN KEDIRI Fahma Laili, Nur; An Nisa Sukmawati, Datin; Probosiwi, Neni; Ilmi, Tsamrotul; Bin Abd Kadir, Mujtahid; Fery Yuniarto, Prayoga; Haryuni, Sri
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 7, No 2 (2024): MARTABE : JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v7i2.401-406

Abstract

Diabetes mellitus tipe 2 merupakan peringkat penyakit terbesar keempat tertinggi di Indonesia. Penyakit diabetes mempengaruhi fungsi normal tubuh dalam mengendalikan glukosa sehingga dapat menyebabkan seseorang terganggu masalah sistem kesehatan tubuh. Sehingga upaya pencegahan kesehatan penyakit ini sangat penting.  Tujuan kegiatan pengabdian masyarakat ini adalah meningkatkan pemahaman pengetahuan tentang penyakit diabetes mellitus dan pemanfaatan tanaman herbal sebagai ramuan untuk penyakit diabetes mellitus. Metode pengabdian masyarakat ini menggunakan metode edukasi dengan sasaran adalah masyarakat di desa selosari kecamatan kandat kabupaten kediri. Pada tahap awal dilakukan sesi pretes. Dilanjutkan tahap pelaksanaan dilakukan edukasi  terkait pengetahuan penyakoit diabetes mellitus dan pemanfaatan tanam herbal. Pada tahap akhir dilakukan post tes.  Hasil pengabdian masyarakat ini menunjukkan terdapat peningkatan pengetahuan masyarakat sebelum dilakukan edukasi yaitu sebesar 40% meningkat setelah dilakukan edukasi sebesar 70%.
GERAKAN MASYARAKAT CERDAS MENGGUNAKAN OBAT (GEMA CERMAT) MELALUI EDUKASI TANYA LIMA O DI PUSKESMAS X KABUPATEN KEDIRI Probosiwi, Neni; Fahma Laili, Nur; Ilmi, Tsamrotul; Siswidiasari, Arifani; Bin Abd Khadir, Mujtahid; An Nisa Sukmawati, Datin
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 7, No 4 (2024): MARTABE : JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v7i4.1460-1465

Abstract

Pedoman layanan farmasi berfungsi sebagai alat bantu dan petunjuk terperinci, bagi para profesional kesehatan yang menawarkan layanan farmasi. (Shankar, et al., 2002). Untuk meningkatkan standar dan kehidupan yang lebih baik bagi pasien, maka diperlukan pelayanan yang berkualitas langsung kepada pasien dan bertanggung jawab terhadap penggunaan sediaan farmasi untuk indikasi penyakit tertentu yang bisa dibeli tanpa resep dokter. Penggunaan obat yang tidak tepat dapat menyebabkan peningkatan biaya perawatan di rumah sakit, polusi terhadap lingkungan, peningkatan angka kematian dan tingkat penyakit yang tidak diinginkan Untuk meningkatkan pemahaman, kesadaran, kepedulian, dan keterampilan masyarakat dalam menggunakan obat dengan bijaksana, diterapkan program yang disebut Gerakan Masyarakat Cerdas Menggunakan Obat (GeMa CerMat). Kementerian Kesehatan RI memperkenalkan program edukasi "Tanya Lima O" yang mewajibkan masyarakat untuk bertanya kepada apoteker tentang lima hal sebelum membeli obat. (1) Nama dan kandungan obat ini apa? (2) Apa khasiat obat ini? (3) Berapa dosis yang disarankan untuk obat ini? (4) Bagaimana cara penggunaannya? (5) Apa efek samping yang mungkin timbul dari penggunaan obat ini?. Metode pelaksanaan kegiatan pengabdian masyarakat ini menggunakan edukasi dengan peserta 20 kader dari salah satu Desa X Kab. Kediri, diskusi, tanya jawab dan presentasi. Dari hasil evaluasi menunjukkan dari 20 peserta, 15 peserta menjawab dengan tepat semua. Hasil menunjukkan bahwa 75% peserta memahami materi yang disampaikan oleh pemateri. Tiga peserta berhasil menjawab tiga pertanyaan dengan akurasi 60%, sementara hanya dua peserta yang mampu menjawab dua pertanyaan dengan akurasi 40%.