Garuda - Garba Rujukan Digital

p-Index From 2021 - 2026

2.036

P-Index

This Author published in this journals

All Journal BALI MEDICAL JOURNAL (BMJ) Jurnal Veteriner Media Penelitian dan Pengembangan Kesehatan Berkala Ilmu Kesehatan Kulit dan Kelamin Folia Medica Indonesiana Jurnal NERS Majalah Obat Tradisional Journal of Islamic Pharmacy Cakrawala: Jurnal Litbang Kebijakan Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia SURABAYA PHYSICAL MEDICINE AND REHABILITATION JOURNAL Indian Journal of Forensic Medicine & Toxicology Indonesia Journal of Physical Medicine and Rehabilitation Indonesia Journal Physical Medicine and Rehabilitation Farmasis: Jurnal Sains Farmasi Borneo Journal of Pharmacy Journal of Tropical Pharmacy and Chemistry Jurnal Sains dan Kesehatan

Hening Laswati Putra

Departemen Kedokteran Fisik Dan Rehabilitasi, Fakultas Kedokteran, Universitas Airlangga, Surabaya, Indonesia

Author-ID : 480421

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

Published : 32 Documents Claim Missing Document

Claim Missing Document

Articles

1 2 3 4

Jus Tomat Meningkatkan Kepadatan Tulang Tikus Menopause (TOMATO JUICE INCREASE BONE DENSITY OF MENOPAUSE RATS) Hening Laswati; Hendy Hendarto; Dian Irawati; Laba Mahaputra
Jurnal Veteriner Vol 16 No 3 (2015)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (153.666 KB)

Osteoporosis in postmenopausal women happened due to estrogen deficiency which leads imbalancebone-formation and bone-resorption process. Recently, phytoestrogen as an alternative hormon replacementtherapy in postmenopausal women could overcome estrogen deficiency. The objectives of this study was toevaluate the effect of tomato juice administration and combination of physical exercise on bone density inestrogen deficiency condition. Twenty eight postovarectomy female rats (Rattus novergicus) were randomizedinto four experiment groups : the controlled group ( 2 mL aquades administration); the exercised group(swimming for 30 minutes, three times in one week), the tomato juice administration every day (44 mg/200g body weight), and the combination exercise and tomato juice administration. Four weeks after treatmentthe samples were collected from os femure for morphological examination. The intervention groups showeda significant difference in bone density with the control group (p<0.05). Bone density highest on the tomatojuice administration group. There is significant difference bone density between tomato juice administrationgroup and the combination group (p<0.05), but no significant difference between physical exercise groupand the combination group. Tomato juice showed an increasing bone density on estrogen deficiencycondition and the combination group have the same effect with the exercised group.

ANALISIS FITOKIMIA EKSTRAK N-HEKSANA DAN FRAKSI DAUN Marsilea crenata Presl. DENGAN GC-MS Burhan Ma'arif; Mangestuti Agil; Hening Laswati
Majalah Obat Tradisional Vol 21, No 2 (2016)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Estrogen deficiency causes various health problems in postmenopausal women, including osteoporosis. Phytoestrogen emerged as a potential alternative of estrogen with minimum side effects. Green clover (Marsilea crenata Presl.) is a typical plant in East Java which suspected contains estrogen-like substances. The aim of this research was to report the phytochemical properties of M. crenata using GC-MS as a preliminary study. M. crenata leaves were dried and extracted with n-hexane, then separated using vacuum column chromatography to get four fractions, after that the n-hexane extract and four fractions were identified with GC-MS. The results of GC-MS analysis showed some compounds contained in M. crenata leaves like monoterpenoid, diterpenoid, fatty acid compounds, and other unknown compounds. The results obtained in this research indicated a promising potential of M. crenata as medicinal plants, especially as antiosteoporotic agent.

AKTIVITAS ANTIOSTEOPOROSIS EKSTRAK ETANOL 96 % DAUN Abelmoschus manihot L. MEDIK SECARA IN VITRO MENGGUNAKAN SEL PREOSTEOBLAS MC3T3-E1 Agnis Pondinekaria Aditama; Mangestuti Agil; Hening Laswati
Majalah Obat Tradisional Vol 21, No 3 (2016)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Osteoporosis is a disease characterized by low bone mass and structural deterioration of bone tissue. Estrogen deficiency causes loss of bone mineral density which causes osteoporosis. Phytoestrogen is a potential alternative of estrogen that can be used as Hormone Replacement Therapy on osteoporosis with minimum side effects. Many edible plants contain phytoestrogens that are believed to promote bone health. Abelmoschus manihot (L.) Medik has been known as a plant that is empirically used in the traditional medicine and has potency to prevent osteoporosis. The aim of this research is to determine whether the Abelmoschus manihot (L.) Medik leaves have the potential to increase bone formation in an in vitro assays using preosteoblast cell line MC3T3-E1. The results showed an increasing activity of Alkaline phosphatase using confocal laser scanning microscopy technique.

Comparison of the Efficacy of Topical Clindamycin versus Niacinamide in the Treatment of Mild to Moderate Acne Vulgaris: a Systematic Review Eden Leonita; Trisniartami Setyaningrum; Mohammad Fathul Qorib; Damayanti -
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 1 (2022): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.1.2022.15-22

Background: Acne vulgaris (AV) is one of the most common skin diseases among teenagers and is treated based on its severity. Mild acne is treated with topical agents, while moderate and severe acne are treated with a combination of topical and systemic agents. Topical agents that are often used for acne are antibiotics, such as topical clindamycin. Widespread use of antibiotics to treat AV causes resistance problems. Therefore, alternative therapies are needed to prevent resistance to topical clindamycin, such as topical niacinamide, which has anti-inflammatory effects without inducing resistance problems. Purpose: To compare the efficacy of topical clindamycin and topical niacinamide in mild to moderate AV. Methods: In this systematic review, a literature search was carried out through 6 databases, following PRISMA 2020 guidelines. Inclusion criteria were written in English or Indonesian, published in 2010-2020, randomized controlled trial (RCT) study design, conducted on human samples, and discussed the efficacy comparison of topical clindamycin and niacinamide in mild to moderate AV. Studies that were not accessible in full-text and based on secondary data were excluded. Quality and risk of bias assessments were done using The Jadad Scale and Risk of Bias 2 (RoB 2). Result: Acne severity was reduced significantly in both topical clindamycin and niacinamide groups, and there was no efficacy difference between these groups. Both topical clindamycin and topical niacinamide can cause mild side effects. Conclusion: Topical niacinamide can be an alternative therapy to topical clindamycin because they are both effective in treating mild to moderate AV.

Selection of Medical Therapy in Glaucoma Patients in the Outpatient Eye Clinic Soetomo General Academic Hospital Surabaya Venansya Maulina Praba; Yulia Primitasari; Mohammad Fathul Qorib; Rozalina Loebis
Folia Medica Indonesiana Vol. 57 No. 4 (2021): December
Publisher : Universitas Airlangga

Highlight:Medical therapy selection in the outpatient eye clinic were determined.Treatment of prostaglandin analogue therapyfor primary open angle glaucoma was the most common glaucoma type. Abstract:Glaucoma is the second leading cause of blindness and the third cause of visual impairment. Glaucoma management includes medical therapy, laser, and incisions. This study aims to determine the selection of medical therapy in the outpatient eye clinic Soetomo General Academic Hospital Surabaya. This study was a retrospective descriptive study. The variables were type of glaucoma, visual acuity, intraocular pressure, and drug therapy. Data processing was done by collecting, grouping, and describing data. Glaucoma was mostly common in 50-64 years old (37.66%), male (50.65%), most patients lived in Surabaya (53.68%), the most common type was Primary Open-Angle Glaucoma (32.90%), the most medical therapy given in the first visit in 2019 was single medical therapy (67.97%), the most single drug therapy was latanoprost (49.68%), the most drugs combination was timolol maleat with acetazolamide (35.14%), the most commonly drugs class were prostaglandin analogues (48.48%), most of the visual acuity values were 6/6 - 6/18 (1,00 – 0,33) (37.88%), most intraocular pressure was in the 11-21 mmHg (62.55%). The most common type of glaucoma was primary open angle glaucoma with the most therapy given was prostaglandin analogue.

Ekspresi HSP 70 dan Ekspresi Reseptor Opioid Mu pada Penurunan Nyeri Terapi Bekam Basah Imam Subadi; Hening Laswati; Harjanto JM
Jurnal Ners Vol. 11 No. 1 (2016): April 2016
Publisher : Universitas Airlangga

Introduction: Wet cupping therapy widely used to reduce the pain, but the mechanisms of pain reduction on wet cuppig therapy is unclear. Stretching and punctures on wet cupping therapy cause stress on the cell. Cells that are stressed express HSP 70 and mu opioid receptors. This study aims to prove the correlation increased expression of HSP 70 and an increase in post-mu opioid receptor wet cupping therapy.Methods: The study is an experimental research design with randomized control group post-test only design. Twenty-four rats type Wistar (Rattus norvegicus) were randomly divided into three groups, each consisting of eight mice are negative control group (normal mice), group induction of pain with Complete Freund's Adjuvant (CFA) alone (positive control) and group by induction of pain and bekam basah therapy (10 puncture and negative pressure: - 200 mmHg, 5 minutes). Samples were taken from the skin and immunohistochemical examination with the monoclonal antibody anti mu opioid receptors. The reaction time pain threshold measured using a hot-plate. Data were analyzed by oneway ANOVA and Pearson Correlation using SPSS version 17.Results: This study shows that there is an increased expression of HSP 70 (P <0.05) compared to the positive control group (p <0.05) and increased expression of mu opioid receptors ( p <0.05) compared to the positive control group (p <0.05). There is an increased pain threshold reaction time (p <0.05) compared to the positive controls (11.78 ± 3.56). There is a correlation between an increased expression of HSP 70 and an increase in mu opioid receptor (β = 0893; p = 0.000) and there was a correlation between the increase in mu opioid receptor with a reaction time of pain threshold (β = 0713; p = 0.002).Discussion: Wet cupping therapy increase HSP 70 expression, opioid mu receptor, and decrease pain level.

Natural Phytoestrogen Contents In Severals Fruit And Leafs; The Future Replacement Hormone Therapy In Menopause Women Hening Laswati Putra; L. Maha Putra
CAKRAWALA Vol 6, No 1: Desember 2011
Publisher : Badan Penelitian dan Pengembangan Provinsi Jawa Timur

Fitoestrogen secara melekul hampir sama dan mempunyai aktifitas sama seperti estrogen dan ditemukan pada jenis tanaman dan buah buahan terutama di negara tropis. Tetapi jumlah kandungan melekulnya hormone belum diketahui. Pada orang-orang menopause dan andropause diperlukan sulih hormone seks karena mereka umumnya mengalami penurunan hormone tersebut secara berarti yang bisa berdampak pada gangguan fungsi organ. Tujuan dari penelitian ini untuk menganalisis kandungan estrogen ekstrak daun pegaga, semanggi, buah tomat dan papaya sehingga dampak positifnya pada komunitas masyarakat yang memerlukan.

Comparison of Acute Level of CK After Five Weeks Eccentric vs Concentric High Intensity Strength Exercise in Healthy Subject Hasni Hasni; Hening Laswati Putra; Nuniek Nugraheni
Surabaya Physical Medicine and Rehabilitation Journal Vol. 1 No. 2 (2019): SPMRJ, Agustus 2019
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Musculoskeletal injuries both in sport and recreational activities, at each age level, can lead to immobilization. Injury and immobilization can lead to muscle strength decrease and deconditioning. These conditions can be addressed by provision of strength training therapy especially for people with low exercise tolerance such as the elderly and patients with chronic disease. Existing studies stated eccentric exercise can increase muscle strength with less energy expenditure compared to concentric exercise. However eccentric exercise can lead to muscle damage indicated with an acute CK level increase, and eccentric exercise has not been carried out regularly for post muscle injuries and deconditioned patients. The American College of Sport Medicine (ACSM) stated strength increase and muscle hypertrophy require high intensity load strengthening exercise with a minimum load of 70% 1 Maximum Repetition. The recommended load was given to the subjects in this research. Our pleriminary study intervention was well tolerated by healthy subjects.Aim: Comparing acute CK level alteration in high intensity eccentric and concentric muscle strengthening exercise on untrained healthy subjects.Methods: Randomized pre test and post test group design. Subjects of the study (n = 16) were untrained healthy males. CK level was evaluated by laboratory test.Results: Our study showed decline of acute CK level in both groups with p value 0.65 and 0.76, respectively. No significant differences found on both groups.Conclusion: The increase of acute CK level after five weeks of eccentric strengthening exercise is not higher than that in concentric strengthening exercise.

PHYTOESTROGEN IN SEVERAL FRUITS AND LEAVES L. Maha putra; Hening Laswati putra
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 18, No 1 (2011)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v18i1.356

Phytoestrogen is molecularly almost similar with and acts the same as estrogen and is found a lot in several fruits and leaves grown either in tropical or subtropical countries. However, the quantity of molecular contents are not yet known exactly. In menopause and andropause, people need substitution of estrogens as a replacement therapy of sex hormone, due to the significant hormone decline and impacted disturbance of several organ functions and thus progressively causing severe organ dysfunctions. The objective of this study was to know the estrogen content by analyzing extractions of pegaga, green clover leaves, tomato and papaya fruit of which certain communites have overviewed contents of the leaves and fruit The samples which were collected for this purpose used 10 times replication in four different groups: the pegaga, green clover leaves, tomato and papaya fruit. All these groups were divided into two (2) subgroups based on the process or subspecies. All samples were made as an infusion 1:4) w/v), and then extracted after centrifugation 1000xg for 15mnts, with 1:5 petroleum ether) v/v). After it was evaporated, each extraction then was kept dry-frozen at –20° C until the analysiswas performed. Solid phase Radioimmunoassay technique was used to identify the estrogen contents, up to a total of 80 samples The binding percentage of each sample was then interpolated on a logit-log paper to find out the real concentrations.14 The lowest estrogen level was found in fresh pegaga leaves extract (Mean+SD) was 47.9+5.5 pg/g, but in dry leaves extract the level was increased twice, about 96.1+11.2 pg/g. Meanwhile the estrogen level in fresh green clover leaves extract was 538.0+30.5 pg/g, more than ten times higher compared to fresh pegaga level, but twice lower than the estrogen level compared to dry green clover leaves extract, which was 1068.0+97.2 pg/g. In the fruit group, the fibrin part of tomatoes had more or less the same estrogen content compared with Thai papaya subspecies, 1037.0+37.7 pg/g and 1175.0+67.7 pg/g, respectively. On the other hand, it was noted that the inner part/fibrin part of tomato had a higher estrogen level of four (4) times compared to the outer part which was 315.0+18.4 pg/g. While it was noted that local Java papaya besides being not so sweet, the estrogen level was also not as high or the same as that found in fresh green clover which is 530.1+50.7 pg/g and 538.0+30.5 pg/g. Based on this study so far, it can be concluded that semanggi/green clover, tomato and papaya could be suggested as a replacement therapy for certain people who are considered to have reduced estrogen content, except that pegaga leaves are not recommended. The last mentioned plant besides that it is difficult to obtain, its estrogen content is also very low.

Effectiveness of Partial Body-Weight Supported Treadmill Training-Audio Cues and Traditional Overground Walking in Improving Gait Speed and Cardiorespiratory Fitness After Stroke Hening Laswati; Meisy Andriana; Ida Yuanita
Indonesian Journal of Physical Medicine & Rehabilitation Vol 4 No 01 (2015): Indonesian Journal Of Physical Medicine and Rehabilitation
Publisher : Indonesian Journal of Physical Medicine & Rehabilitation

Objective: To compare the effectiveness of Partial Body-Weight Supported Treadmill Training-Audio Cues (PBWSTT-AC) and the traditional over ground walking in improving gait speed andcardiorespiratory fitness after stroke.Methods: pretest-posttest control group design of patients with sub-acute and chronic ischemicstroke who came to Physical Medicine and Rehabilitation (PMR) Department of Dr. Soetomo andAirlangga University Hospital Surabaya. Patients with onset 3 weeks until 10 years, age between 21until 70 years old, able to walk independently for 6 minutes, sufficient vision and hearing and canfollow simple instructions were included in this study. There were 18 patients at beginning and 16patients completed the study. Patients underwent walking exercise for 20 minute, 3 times a week for12 sessions. PBWSTT-AC group received metronome auditory rhythmic stimulation, while controlgroup received traditional walking exercise with customized speed according to patient’s preference.Gait speed were assessed by 10 meter Walk Test and cardiopulmonary endurance counted fromresting heart rate.Results: There were improvements in gait speed and cardiorespiratory fitness within each subjectgroup. Traditional group showed significantly larger increases in fast gait speed (p=0.023) but notin self-selected gait speed (p=0.002). PBWSTT-AC group showed significantly larger decreases(p=0.002) in resting heart rate (p=0.003).Conclusion: PBWSTT-AC was not shown to be superior to traditional walking in improving gaitspeed, but superior in improving cardiorespiratory fitness. Further study are needed to evaluate thelong-lasting effect of using PBWSTT-AC in improving cardiorespiratory fitness.Keywords: Partial Body-Weight Supported Treadmill Training-Audio Cues, gait speed, cardiorespiratory fitness

Co-Authors Agnis Pondineka Ria Aditama Agustina Konginan Amalia, Dilla Ananda, Naoval Diza Andriana, RA Meisy Anisah Mahardiani Anita Ratnawati Arief Suryadinata Artabah Burhan Ma'arif Burhan Ma'arif Burhan Ma'arif Burhan Ma’arif Burhan Ma’arif Burhan Ma’arif Damayanti - Denis Dian Irawati Dian Marta Sari Dilla Amalia Eden Leonita Faisal Akhmal Muslikh Fazia Firdausy, Alif Firman Guhir, Abdul Malik Harjanto JM Harjanto JM Hasni Hasni Hendy Hendarto Ida Yuanita Ikhwan Muhammad Imam Subadi J. A. Pangkahila Jatmiko, Ricky Arie L. Maha putra L. Maha Putra Laba Mahaputra Luthfi Achmad Muchlasi M. Artabah Muchlisin Ma'arif, Burhan Mangestuti Agil Marta Ika Riyana Martha Kurnia Kusumawardani Maximus M Taek Mei Wulan, Sri Mardjiati Meilina Ratna Dianti Muslim, Menara Nabila Rosa Nabilah Ishanan Ramadhan Nasronudin Nasronudin Nuniek Nugraheni Nurwijayanti Nury Nusdwinuringtyas Patricia Maria Kurniawati Paulus, Anitta Florence Stans Poerwandari, Dewi Pramudita Riwanti Prawitri, Yudith Dian Primitasari, Yulia Purbosari, Ira Rahmi Annisa Rejeki, Purwo Sri Retno Widyowati Ria Ramadhani Dwi Atmaja Riyanti, Anisa Eka Rozalina Loebis, Rozalina Saidah, Nisfatul Lailatus Sari, Dewi Perwito Setiawati, Rosy Suyoko, Andri Tedjasukmana, Deddy Trisniartami Setyaningrum Usman Hadi Wardhani, Indrayuni Lukitra Wicaksono Alim Budihartanto Widjanantie, Siti Chandra Wigati, Kristanti Wanito Wirda Anggraini Yuanita, Ida

Title

Found 32 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 32 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 32 Documents
Search