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All Journal JURNAL ISTEK Jurnal Farmasi Sains dan Komunitas Jurnal Sains Teh dan Kina Jurnal SOLMA PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia Media Karya Kesehatan Jurnal Pengabdian Kesehatan Poltekita: Jurnal Pengabdian Masyarakat Jurnal Insan Farmasi Indonesia Jurnal EduHealth Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Pengabdian Pada Masyarakat Jurnal Ilmiah Farmasi Simplisia Jurnal Pengabdian Masyarakat dan Riset Pendidikan Jurnal Medika Farmaka Medical Sains : Jurnal Ilmiah Kefarmasian Indonesian Journal of Science and Education Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Mimin Kusmiyati, Mimin
Prodi D-3 Farmasi, Poltekkes Kemenkes Bandung, Bandung, Indonesia
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Uji Aktivitas Antioksidan dan Antikolesterol Seduhan Produk The Putih Celup (Camellia sinensis L.) Mimin Kusmiyati; Trinovani, Elvi; Rhamadianto, Muhamad Iqbal; Kusumah, Raden Minda
JURNAL ILMIAH FARMASI SIMPLISIA Vol. 5 No. 1 (2025): Juni 2025
Publisher : Jurusan Farmasi, Politeknik Kesehatan Kementerian Kesehatan Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/jifs.v5i1.843

Abstract

Teh (Camellia sinensis L.) kaya akan senyawa bioaktif polifenol yang didominasi oleh katekin. Hal ini menjadikan teh memiliki manfaat untuk kesehatan diantaranya sebagai antioksidan dan antikolesterol. Teh putih diperoleh dari daun teh yang mengalami proses minimal dan umumnya tidak melalui fermentasi, sehingga teh putih memiliki aktivitas antioksidan dan efek penurun kolesterol yang lebih unggul dibandingkan jenis teh lainnya. Penelitian ini ditujukan untuk mengevaluasi aktivitas antioksidan pada sampel teh putih celup merek A, B, dan C berdasarkan parameter IC50 melalui uji DPPH dan aktivitas antikolesterol berdasarkan parameter EC50 melalui pengujian Liebermann - Burchard serta menentukan suhu dan waktu penyeduhan optimal penyeduhan untuk sampel tersebut. Hasil penelitian menunjukkan ketiga sampel teh putih celup memiliki aktivitas antioksidan dengan nilai IC50 berkisar antara 75,30 hingga 96,50 ppm serta aktivitas antikolesterol dengan nilai EC50 antara 110,49 hingga 123,40 ppm.  Sampel teh celup merek A yang diseduh pada suhu 95℃ selama 9 menit menunjukkan aktivitas antioksidan dan antikolesterol tertinggi dengan nilai IC50 sebesar 75,30 ± 1,86 ppm dibandingkan terhadap IC50 baku kuersetin 4,02 ppm dan EC50 sebesar 110,49 ± 0,66 ppm. Analisis statistik repeated ANOVA menunjukkan nilai p.Sig<0,05 sehingga dapat disimpulkan variasi suhu penyeduhan berpengaruh secara signifikan terhadap aktivitas antioksidan dan antikolesterol. Suhu penyeduhan optimum adalah pada suhu 95℃ selama 9 menit..
Pemanfaatan Teh Hijau sebagai Obat Kumur dalam Upaya Peningkatan Perekonomian Masyarakat Desa Talagasari dan Sindangsari: Utilization of Green Tea as Mouthwash in an Effort to Improve the Economy of the Talagasari and Sindangsari Village Communities Kusmiyati, Mimin; Novani, Elvi Tri; Widyastuti, Tri; Purkon, Dicki Bakhtiar; Herdiana, Irvan; Noviapratami, Nikky; Fatimah, Cucu
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 4 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i4.8877

Abstract

Gingivitis is an oral health disease characterized by inflammation of the gingival tissue that appears reddish. One way to prevent and treat gingivitis is to use mouthwash. Green tea herbal mouthwash is used to treat gingivitis. Green tea is known to have antimicrobial activity that causes gingivitis. The increase in public knowledge about green tea mouthwash increased by 41%. This shows public understanding of the benefits of green tea mouthwash for preventing gingivitis and the economic value of green tea herbal mouthwash products.
Review : Aktivitas Farmakologi Rumput Laut Genus Gracilaria (Rhodopyceae) Nurazizah, Siska; Rustamsyah, Ardi; Perdana, Farid; Sujana, Dani; Kusmiyati, Mimin
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Vol. 10 No. 1 (2023): February
Publisher : Faculty of Pharmacy, Widya Mandala Surabaya Catholic University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v10i1.4318

Abstract

Penyebaran rumput laut di Indonesia berada hampir diseluruh penjuru tanah air, namun produksi dan perdagangan rumput laut Indonesia sampai saat ini didominasi oleh genus Gracilaria dari kelas Rhodopyceae sebagai penghasil agar. Beberapa penelitian telah dilakukan dan menunjukan aktivitas dari Gracilaria. Tujuan review artikel ini adalah memberikan informasi tentang aktivitas farmakologi genus Gracilaria, dengan menggunakan metode studi literatur dari beberapa penelitian mengenai aktivitas dari Gracilaria. Beberapa spesies dari genus ini, berpotensi untuk aktivitas antioksidan, antibakteri, terapi adjuvans pada penyakit peridontal, antidiabetes, antiobesitas, antikolesterol, antiosteoklas, hepatoprotektor, antikanker, homeostatis, antikoagulan, antiulcer, dan imunostimulan.
Gas Chromatography Mass Spectroscopy (GCMS) Qualitative Analysis for Morphine, Heroin and Codeine used in Doping Haerussana, Ayu Nala El Muna; Mimin Kusmiyati; Irvan Herdiana
Indonesian Journal of Science and Education Vol. 7 No. 1 (2023): Indonesian Journal of Science and Education
Publisher : Universitas Tidar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31002/ijose.v7i1.207

Abstract

Three types of doping drugs, morphine, heroin, and codeine were analyzed qualitatively in urine using GCMS: HP5MS column containing a nonpolar substance, phenylmethyl siloxane, with a temperature range of 90-250ºC and a rate of increase of 10ºC/minute. Diethyl ether was used to extract morphine, codeine, and heroin. The extractions were performed at pH 8, the organic phase was evaporated, followed by derivatization. Morphine and its derivatives were treated with a solution of N-methyl-N-trimethylsilyl-trifluoroacetamide and N-methyl-bis-trifluoroacetamide. The results of the gas chromatographic analysis showed that the retention times of morphine, heroin, and codeine the retention times were 8.01, 7.32, 6.21 minutes, while those of their derivatives were 8.10, 8.10, 7.95 minutes respectively. The identification of each drug using mass spectrometry revealed that their mass spectra were identical to the standard. The mass spectra of the derivatives: morphine-TMS and codeine-TMS showed a resemblance index of 93% respectively compound to the standard, with a detection limit of 2 ug/ml.
Pendampingan Masyarakat Mengenai Pemanfaatan Tanaman TOGA sebagai Pemenuhan Gizi di Kecamatan Kawali Kabupaten Ciamis: Community Assistance Regarding the Use of TOGA Plants to Fulfill Nutrition in Kawali District Ciamis Regency Trinovani, Elvi; Kusmiyati, Mimin; Purkon, Dicki Bachtiar; Fatimah, Cucu
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 9 No. 8 (2024): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v9i8.6976

Abstract

Fulfilling nutritional intake can be done by utilizing TOGA plants. TOGA plants have high nutritional content to support the fulfillment of daily nutritional needs. The aim of community service related to TOGA plants is to increase community understanding and access to nutritional sources needed to prevent high levels of malnutrition. The method used is Participatory Action and Learning and evaluated using pre-test and post-test methods. There was an increase in knowledge scores at the end of the training, namely an average of 15.8 points. The variation in knowledge scores on the pre-test tends to be higher than on the post-test, this shows that there is a similar perception of understanding of the material at the end of the training.
Pelatihan dan Pemanfaatan Minuman Herbal Teh Hijau sebagai Upaya Meningkatkan Imunitas Tubuh di Desa Sindangsari dan Talagasari Kecamatan Ciamis: Training and Utilization of Green Tea Herbal Beverage as an Effort to Enhance Body Immunity in Sindangsari and Talagasari Villages, Ciamis Subdistrict Kusmiyati, Mimin; Sudaryat, Yayat; Herdiana, Irfan; Widyastuti, Tri; Fatimah, Cucu
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 9 No. 8 (2024): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v9i8.7052

Abstract

Green tea contains polyphenol and flavonoid compounds which have many benefits such as antioxidants, anti-inflammatory and antibacterial. Even though it is known that tea has various benefits, the level of public knowledge regarding this is still low. So this training aims to increase public awareness about the benefits of green tea. The training and evaluation methods used were post-test and pre-test by providing training on making and using green tea herbal drinks. Based on the results of the training, there was an increase in public knowledge of 15% after the training, which shows the effectiveness of training as an effective tool in increasing public understanding and knowledge regarding the benefits of green tea herbal drinks.
Qualitative Examination Of Amfetamine And Ephedrine In Urine In Doping Using Gas Chromatography-Mass Spectrometry Method Kusmiyati, Mimin; Trinovani , Elvi; Sudaryat , Yayat; Bakhtiar , Dicky
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (246.939 KB)

Abstract

Amphetamines and ephedrine are stimulant class doping drugs which have the effect of reducing fatigue and drowsiness, increasing alertness, physical strength, mental sense of competition and competitive attitude. Analysis of doping drugs in urine that has been recommended by the International Olympic Committee, including Gas Chromatography-Mass Spectrometry. Derivatization is carried out to change the polarity of the analyte, making it easier to become a gas and stable to heating. This study was conducted for qualitative analysis of amphetamine and ephedrine, using an HP5MS column containing non-polar phenyl methyl siloxane, temperature 100-250oC with a temperature increase of 10oC/minute. Then it was extracted with a mixture of diethyl ether-ethylacetate (1:1) in an alkaline medium pH 8, the organic layer was evaporated then derivatized with trifluoro-acetic acid-anhydride and ephedrine with acetic-anhydride-pyridine (3:2). The final results showed that the retention times of amphetamine and ephedrine were 10.47 and 4.9 minutes. While the derivatives are 13.34 and 5.50 minutes. Identification using mass spectrometry for each compound showed that the mass spectra matched the Ref. and the amphetamine and ephedrine structural similarity index was 96% and the detection limit for each compound was 2 ug/ml.
Edukasi Pemimpin Desa dalam Menjaga Kesehatan dan Kebersihan Lingkungan: Pengabdian Masyarakat Kusmiyati, Mimin; Fathurrahman, Muhammad; Astuti, Puji; Ayu Lestari, Putri
Jurnal Pengabdian Masyarakat dan Riset Pendidikan Vol. 3 No. 3 (2025): Jurnal Pengabdian Masyarakat dan Riset Pendidikan Volume 3 Nomor 3 (Januari 202
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jerkin.v3i3.394

Abstract

Kesehatan dan kebersihan lingkungan desa sangat bergantung pada peran pemimpin desa dalam mengedukasi masyarakat. Kegiatan pengabdian kepada masyarakat ini dilakukan oleh Generasi Muda Forum Komunikasi Dosen (GM FKD) pada 20 Maret 2025 di salah satu desa di Kabupaten Bandung Barat yang bertujuan meningkatkan pemahaman pemimpin desa melalui seminar edukasi tentang pengelolaan sampah, sanitasi, dan kesehatan lingkungan. Seminar dilakukan dengan metode ceramah interaktif dan diskusi. Hasil kegiatan menunjukkan bahwa peserta antusias dalam memahami materi yang disampaikan. Diskusi mengungkapkan berbagai tantangan di desa, seperti minimnya fasilitas pengelolaan sampah, maraknya Tempat Pembuangan Sementara (TPS) yang Tidak Teratur dan rendahnya kesadaran masyarakat dalam menjaga lingkungan. Melalui seminar ini peserta memperoleh solusi praktis, seperti sosialisasi kebersihan dan program berbasis komunitas. Umpan balik dari peserta menunjukkan adanya peningkatan pemahaman mengenai peran mereka dalam menjaga kebersihan lingkungan. Mayoritas peserta menyatakan kesiapan untuk menerapkan ilmu yang diperoleh dalam kebijakan desa dan kehidupan sehari-hari. Diharapkan pemimpin desa dapat lebih aktif dalam mendorong perilaku hidup bersih dan menciptakan lingkungan desa yang lebih sehat dan berkelanjutan.
Cost-effectiveness analysis of the use of antibiotics for typhoid fever inpatients in RSUD Bayu Asih Purwakarta Purkon, Dicki Bakhtiar; Agustin, Himeliya; Widyastiwi, Widyastiwi; Kusmiyati, Mimin; Fadhlillah, Faizah Min
JURNAL ILMU KEFARMASIAN INDONESIA Vol 23 No 2 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i2.1679

Abstract

Typhoid fever is an infectious disease caused by Salmonella typhi, commonly treated with antibiotics to promote recovery and prevent complications. This study aimed to evaluate both the therapeutic effectiveness (clinical outcomes such as fever resolution and hospital stay duration) and the cost-effectiveness (economic efficiency of antibiotic use) in inpatients with typhoid fever at RSUD Bayu Asih Purwakarta (Bayu Asih District Hospital, Purwakarta) in 2023. A retrospective descriptive design was applied using 75 medical records from January to December 2023. Results showed that levofloxacin had the highest therapeutic effectiveness, reflected by the shortest hospitalization (3.5 days), whereas ceftriaxone was the most cost-effective, with an Average Cost-Effectiveness Ratio (ACER) of Rp. 194,858.78 per treatment. The Incremental Cost-Effectiveness Ratio (ICER) analysis indicated that the additional cost required for levofloxacin compared to ceftriaxone was disproportionate to the clinical benefit gained. In conclusion, while levofloxacin provides faster recovery, ceftriaxone remains the preferred option considering its superior cost-effectiveness. These findings emphasize the need to balance clinical outcomes and economic efficiency when determining antibiotic policies for typhoid management.
Analisis efektivitas biaya penggunaan antibiotik untuk pasien rawat inap demam tifoid di RSUD. Bayu Asih Purwakarta Purkon, Dicki Bakhtiar; Agustin, Himeliya; Widyastiwi, Widyastiwi; Kusmiyati, Mimin; Fadhlillah, Faizah Min
JURNAL ILMU KEFARMASIAN INDONESIA Vol. 23 No. 2 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i2.1679

Abstract

Typhoid fever is an infectious disease caused by Salmonella typhi, commonly treated with antibiotics to promote recovery and prevent complications. This study aimed to evaluate both the therapeutic effectiveness (clinical outcomes such as fever resolution and hospital stay duration) and the cost-effectiveness (economic efficiency of antibiotic use) in inpatients with typhoid fever at RSUD Bayu Asih Purwakarta (Bayu Asih District Hospital, Purwakarta) in 2023. A retrospective descriptive design was applied using 75 medical records from January to December 2023. Results showed that levofloxacin had the highest therapeutic effectiveness, reflected by the shortest hospitalization (3.5 days), whereas ceftriaxone was the most cost-effective, with an Average Cost-Effectiveness Ratio (ACER) of Rp. 194,858.78 per treatment. The Incremental Cost-Effectiveness Ratio (ICER) analysis indicated that the additional cost required for levofloxacin compared to ceftriaxone was disproportionate to the clinical benefit gained. In conclusion, while levofloxacin provides faster recovery, ceftriaxone remains the preferred option considering its superior cost-effectiveness. These findings emphasize the need to balance clinical outcomes and economic efficiency when determining antibiotic policies for typhoid management.
Co-Authors A Rustamsyah A Rustamsyah, A Afifah Rahmawati Agustin, Himeliya Angreni Ayuhastuti Ansyirohanisa Ansyirohanisa Ardi Rustamsyah Ardi Rustamsyah Ardi Rustamsyah Asep Supriadin, Asep Ayu Lestari, Putri Bakhtiar , Dicky Citra Ratu Pelangi Citra Ratu Pelangi, Citra Ratu Dadan Rohdiana Dani Sujana Dicki Bakhtiar Purkon Elvi Trinovani, Elvi Faizah Min Fadhlillah Fatimah, Cucu Fitri Retna Wijayanti Fitriana Fitriana Haerussana, Ayu Nala El Muna Hendriani, Yenni Herdiana, Irfan Hotimah, Alni Khusnul Irvan Herdiana Irvan Herdiana Isti Agnia Lutfiah Isti Agnia Lutfiah, Isti Agnia Karina Agust Kusumah, Raden Minda Muhamad Iqbal Rhamadianto Muhammad Fathurrahman Nainggolan, Aurelya Veny Kurnia Ningsih, Padmasari Diah Ayu Kumala Nizella Syahla Novani, Elvi Tri Noviapratami, Nikky Nunung Kurniasih, Nunung Nurazizah, Siska Perdana, Farid Puji Astuti Purkon, Dicki Bachtiar Rhamadianto, Muhamad Iqbal Riska Puspita Sari Riza Wafdan Sarah Nur Islami Sarah Nur Islami, Sarah Nur Siti Nuraeni Srinati, Ine Sudaryat , Yayat Sufa, Hafizah Ilmi Tanika Miatul Hadid Tina Dewi Rosahdi, Tina Dewi Tri Widyastuti Trinovan, Elvi i Trinovani , Elvi Vindi Nur Amalia Yayat Sudaryat Yayat Sudaryat Yoga Yuniadi Zahra Anggraeni Zahwa Ainunnisya Nur Aisyah Zulfakor, Dava