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All Journal Pharmaciana: Jurnal Kefarmasian Pharmacon Majalah Obat Tradisional PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Abdi Geomedisains Medical Sains : Jurnal Ilmiah Kefarmasian Prosiding University Research Colloquium Innovative: Journal Of Social Science Research Maeswara: Jurnal Riset Ilmu Manajemen dan Kewirausahaan Usadha Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Kefarmasian Indonesia Pharmacon: Jurnal Farmasi Indonesia Global Management: International Journal of Management Science and Entrepreneurship Journal of Pharmascience Biodiversitas Journal of Biological Diversity
Anita Sukmawati
Fakultas Farmasi, Universitas Muhammadiyah Surakarta
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Study of Curcuma diversity from Central Java, Indonesia for sunscreen and antioxidant activity based on quantitative phytochemical analysis HENNY NURHASNAWATI; REKSI SUNDU; ANITA SUKMAWATI
Biodiversitas Journal of Biological Diversity Vol. 24 No. 12 (2023)
Publisher : Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/biodiv/d241249

Abstract

Abstract. Nurhasnawati H, Sundu R, Sukmawati A. 2023. Study of Curcuma diversity from Central Java, Indonesia for sunscreen and antioxidant activity based on quantitative phytochemical analysis. Biodiversitas 24: 6880-6887. Indonesia is home to various plants, including those of the genus Curcuma. This study aimed to determine the effect of total phenolic and flavonoid content of Curcuma on antioxidant activity and SPF values. It is known that this rhizome contains secondary metabolites such as flavonoids and phenols, which are known to have antioxidant potential and are believed to act as natural ingredients for sun protection products. The samples used in this study were rhizomes of five Curcuma species from Central Java, namely C. aeruginosa, C. longa, C. mango, C. xanthorrhiza, and C. zedoaria. Alkaloids, flavonoids and tannins are present in all samples. UV-Vis spectrophotometry was used with the following results: the flavonoid total content ranged from 0.94-243.5 mg QE/g, while the total phenolic from 11.27-109.23 mg GAE/g. The DPPH and ABTS test for antioxidant activity showed that C. longa had the highest activity with an IC50 of 78.79 and 0.4273 ppm. The highest SPF values in C. longa were 31.55-36.97 (high protection). The results of the data analysis using the Spearman correlation test revealed a significant correlation between the antioxidant activity and SPF with the flavonoid and phenolic content of the Curcuma extracts.
Edukasi Kesehatan Kognitif dan Senam Otak Lansia Menuju Lansia Mandiri dan Bahagia pada Ibu-Ibu Penggerak PKK Desa Mliwis, Boyolali, Jawa Tengah Juwita Rahmawati; Tri Yulianti; Annisa Nur Lathifah Amanda Putri; Septiana Windarti; Arini Fadhilah Fadhilah; Arifah Sri Wahyuni; Anita Sukmawati; Peni Indrayudha; Gunawan Setyadi; Febri Wulandari; Teguh Imanto; Santhyami Santhyami
Abdi Geomedisains Vol. 6, No. 2, December 2025
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

A prevalent issue among the elderly is cognitive deterioration. Modifications in behavior and the adoption of a healthy lifestyle have been demonstrated to mitigate cognitive decline in the elderly. The objective of community service initiatives is to disseminate knowledge regarding cognitive health in the elderly and to offer brain workouts to the community, particularly targeting women who are PKK activists in Mliwis Village. This community service initiative employs an instructional methodology that incorporates PowerPoint presentations and leaflets, utilizing a one-group pre-test and post-test design. The event took place at the Posyandu Sidorejo in Mliwis Village, Boyolali. The target audience for this activity was PKK mothers in Mliwis Village, Boyolali Regency, Central Java. To measure the level of knowledge about cognitive health, a questionnaire developed by the community service team was used. This activity consisted of six stages, namely opening, pretest, education, group brain exercises, discussion, and post-test. 51 participants, comprising PKK mothers, attended this activity. The most extensive age range was 31-40 years old, with 16 (31.4%) participants, and the largest occupation was housewife, with 36 (70.6%) participants. The education and discussion activities went well. The enthusiasm of the participants also increased with the joint brain exercises. The average pretest and posttest scores were 90.26 ± 10.78 and 93.68 ± 7.50, respectively. There was a significant difference in knowledge between the pretest and post-test measurements (p = 0.034; < 0.05). It is hoped that this educational activity will help form independent and happy elderly people.
Nothopanax scutellarium: Natural Hair Growth Plant Diski Wahyu Wijianto; Arifah Sri Wahyuni; Anita Sukmawati; Fazleen Izzany Abu Bakar
Pharmacon: Jurnal Farmasi Indonesia Vol. 22 No. 1 (2025)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v22i1.11693

Abstract

Hair plays an important role in supporting appearance and self confidence, but problems with hair loss and slow hair growth still often occur; Mangkokan leaves (Nothopanax scutellarium) are known to contain flavonoids such as quercetin which can stimulate hair growth through various mechanisms, and nanoemulsion formulations have been shown to increase the absorption of these active compounds, so this study aims to examine the effectiveness of mangkokan leaves on hair growth through a systematic review based on PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines with a literature search until November 16, 2024 in the Emerald Publishing, SpringerLink, EBSCO, Cochrane, ProQuest, Science Direct, Scopus, and PubMed databases, of the 68 articles found, only 5 studies met the inclusion criteria after screening, and the results showed that the formulation of mangkokan leaves in the form of ethosomal gel or phytosome lotion at a concentration of 25% was most effective in stimulating hair growth with a mechanism involving the activation of endothelial nitric oxide synthase (eNOS) to increase blood supply to follicles, regulation of nitric oxide (NO) balance and decreased inflammation by quercetin, inhibition of the enzyme 5-alpha reductase to reduce dihydrotestosterone (DHT) levels, as well as increasing the expression of growth factors such as insulin-like growth factor-1 (IGF-1), vascular endothelial growth factor (VEGF), keratinocyte growth factor (KGF), and hepatocyte growth factor (HGF), which overall support the extension of the anagen phase (active hair growth phase) and improve hair health, so that mangkokan leaves have high potential as an active ingredient in hair care products, although further research is still needed to ensure their long-term safety and effectiveness.
Co-Authors A.A. Ketut Agung Cahyawan W AA Sudharmawan, AA Abda Abda Adellia Agustina Nur Saputri Ahmad Fauzi Ahmad Rajali Andi Suhendi Andriyas Nisfiliyah Annisa Nur Lathifah Amanda Putri Arifah Sri Wahyuni Arini Fadhilah Arsanto, Hugeng Wimbo Asyhar Masyhuda Aysha, Miranda m Ayyun, Qurrota Azistyna, Delvi Yulia Clara Cendera Marthadilla Dewi Rahmawati DEWI RAHMAWATI Dwi Hernuningsih Elbira J.A Purnomo Erindyah R. Wikantyasning Evi Mulyani Fahmi Alief Maulana Farida Rahayu Fazleen Izzany Abu Bakar Febri Wulandari Fitri Kurniasari Freddy Johannis Rumambi Gunawan Setyadi Haerani, Dian Hairi, Dewi Gulyla HENNY NURHASNAWATI Hidayah Karuniawati Hilda Srivaliana Ilham Ika Trisharyanti Dian Kusumowati Indriyani, Yuvita Dewi Intan Nurhanifah Isna Vira Risdiyanti Juwita Rahmawati Laeha, Ms. Nur-ainee Lestari, Ratih Guswinda Lintang Karengga Ihsani Lintang Titian Cahya M. A., Rhinomuraena Makanoneng, Jacqueline Marisi Pakpahan Masyhuda, Asyhar Maulana, Fahmi Alief Mika Tri Kumala Swandari Mika Tri Kumala Swandari Miranda m Aysha Ms. Nur-ainee Laeha Muhammad Aditya, Muhammad Muhammad Bakhtiar Mulyani, Risya Naibaho, Nora Nisfiliyah, Andriyas Nugraha, Adie Nur Aini Nurhanifah, Intan Nurhasan, Dede Oktavia Permata Fenthiadewi Palupi Finofasipa Patrick Patrick Peni Indrayudha Pratama, Ilham Okta Purbandari Ajeng Sarweningtyas Purnomo, Elbira J.A Putra, Handre Qurrota Ayyun Radixza Afiffatul Rohmanna Ramdani, Tasya Eka Ratna Yuliani Ratna Yuliani Razali, Roni REKSI SUNDU Riauwati, Rossa Rifa Iztihara Rihi Hina, Bara Jonathan Ririn Setiawati Rohmanna, Radixza Afiffatul Rudianto Rudianto Salam, Bernadi Gamal Salsabila, Unik Hanifah Santhyami Saputri, Adellia Agustina Nur Septiana Windarti Septiani, Adiva Metri Seran, Ardi Seran, Ardi Peterson Setiawati, Ririn Setyani, Yerika Nova Setyawan, Filippus Cahyo Setyo Nurwaini Sundari, Sri Suprapto Suprapto Tangkudung, Audrey G Tangkudung, Audrey G. Teguh Imanto Tri Mulyani Tri Mulyani Tri Yulianti Triyatno, Sabrina Azizah Umi Khasanah Umi Khasanah Wibowo, Danang Novianto Wijianto, Diski Wahyu Yerika Nova Setyani Yumna Azzuhdiyah Yuvita Dewi Indriyani Zakky Cholisoh  Pakpahan, Marisi