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Physicochemical Profile of Red Ginger (Zingiber officinale) SNEDDS as Potential Antidiabetic Sumantri Abdullah, Surya; Sudewi, Sri; Antasionasti, Irma; Rezky Putri Indarwati Abdullah
Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ) Vol. 8 No. 2 (2025): Jurnal Farmasi Medica
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pmj.v8i2.64731

Abstract

This study developed a Self-Nanoemulsifying Drug Delivery System (SNEDDS) of red ginger (Zingiber officinale var. rubrum) to enhance its stability and bioavailability. 8 formulations (F1–F8) were tested with varying Tween 80 : PEG 400 ratios (Smix 4.5 mL). Formula F7 (2.8 : 1.8 mL) produced a water-clear emulsion with pH 5.20 ± 0.02 and excellent stability for 28 days. PSA results showed droplet size 20.33 ± 0.57 nm, PDI 0.430 ± 0.053, and zeta potential −19.58 ± 1.50 mV. These findings indicated that F7 is the optimum, physicochemically stable SNEDDS formulation, potentially improving solubility and oral bioavailability of red ginger’s active compounds as a phytopharmaceutical antidiabetic candidate Keywords: red ginger, SNEDDS, nanoemulsion, physicochemical stability
Biostimulasi Perkecambahan Padi Lokal Yang Mengalami Dormansi Melalui Optimalisasi Lama Perendaman Ekstrak Keong Mas Diperkaya Bioaktivator Pgpr Sudewi, Sri; Noer, Hasmari; Jaya, Kasman; Sulaeman, Sulaeman
Jurnal Penelitian Pertanian Terapan Vol 25 No 3 (2025)
Publisher : Politeknik Negeri Lampung.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25181/jppt.v25i3.4081

Abstract

Seed dormancy poses a serious challenge when aiming for precise and uniform sowing times in crop cultivation activities. Dormancy can reduce seed viability thus inhibiting germination and early plant growth. The purpose of this study was to test the effectiveness of gold snail extract enriched with PGPR (Plant Growth Promotion Rhizobacteria) bioactivator by optimizing the length of soaking in local rice seeds that experience dormancy. The research was conducted using a Completely Randomized Design (CRD) with 5 treatments of control soaking duration (P0), 12 hours soaking duration (P1), 24 hours (P2), 36 hours (P3) and 48 hours (P4) with 4 replications so that a total of 20 experimental units were obtained. Each experimental unit consisted of 25 local Kamba rice seeds by observing the percentage of germination, vigor index, growth speed, fresh weight, dry weight, root length and pH changes during the fermentation process. The results showed that various treatments of soaking time in gold snail extract enriched with PGPR bioactivator did not provide statistically significant differences in the germination of local rice seeds that experienced dormancy. However, there was an increasing trend in all observation parameters indicating that the viability and vigor of seeds soaked in gold snail extract for 36 hours (P3) were better than the control. pH and temperature observed before and after fermentation, showed conditions that remained optimal. The combination of gold snail extract added with PGPR as a bioactivator is an alternative solution that can accelerate the breaking of dormancy, increase seed viability and vigor as an effort to support more optimal and sustainable early growth of rice plants.
Perbaikan sifat tanah eks-likuifaksi melalui amandemen bahan organik serta implikasinya terhadap pertumbuhan dan hasil bawang merah lokal palu Sudewi, Sri; Minarni; Bangkele, Lisa Indriani; Jumardin; Sayani
Jurnal AGRO Vol. 12 No. 2 (2025)
Publisher : Jurusan Agroteknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/j.agro.51372

Abstract

Tanah bekas likuifaksi umumnya memiliki kandungan bahan organik sangat rendah (<1%), struktur tanah rusak, porositas tidak stabil, serta aktivitas mikroba yang menurun sehingga memerlukan amandemen organik untuk memulihkan sifat fisik, kimia, dan biologinya. Pupuk kandang sapi menjadi pilihan solusi karena kaya C-organik dan unsur hara makro serta mudah terdekomposisi, sedangkan arang sekam berperan memperbaiki aerasi dan porositas tanah berpasir. Penelitian ini bertujuan mengkaji efektivitas pupuk kandang sapi dan arang sekam sebagai bahan amandemen tanah eks-likuifaksi di Desa Jono Oge serta dampaknya terhadap pertumbuhan dan hasil bawang merah lokal Palu. Penelitian menggunakan Rancangan Acak Lengkap (RAL) dengan tujuh perlakuan, yaitu amandemen tanah + pupuk kandang (1:1), tanah + arang sekam (1:1), tanah + pupuk kandang + arang sekam (1:1:1), tanah + pupuk kandang (2:1), tanah + arang sekam (2:1), tanah + pupuk kandang + arang sekam (2:1:1), dan tanah tanpa amandemen sebagai kontrol dengan lima ulangan. Parameter yang diamati meliputi sifat fisik, kimia, dan biologi tanah serta pertumbuhan dan hasil tanaman. Hasil penelitian menunjukkan bahwa perlakuan kombinasi tanah bekas likuifaksi, pupuk kandang dan arang sekam rasio 1:1:1 memiliki tinggi tanaman (44,50 cm), bobot segar umbi (20,70 g), dan bobot kering umbi (8,97 g) bawang merah lokal palu tertinggi. Aplikasi bahan organik dengan proporsi seimbang terbukti efektif merehabilitasi tanah bekas likuifaksi dan meningkatkan produktivitas bawang merah lokal Palu sehingga berpotensi diterapkan sebagai strategi pertanian berkelanjutan pada lahan pasca bencana. ABSTRACT Post-liquefaction soil has very low organic matter content (<1%), damaged soil structure, unstable porosity, and decreased microbial activity, so it requires organic amendments to restore its physical, chemical, and biological properties. Cow manure is a solution of choice because it is rich in organic carbon and macronutrients and is readily decomposed, while rice husk charcoal improves aeration and porosity in sandy soil. This study aims to assess the effectiveness of cow manure and rice husk charcoal as amendments to post-liquefaction soil in Jono Oge Village and their impact on the growth and yield of local shallots in Palu. The study used a Completely Randomized Design (CRD) with seven treatments:  soil + manure (1:1), soil + rice husk charcoal (1:1), soil + manure + rice husk charcoal (1:1:1), soil + manure (2:1), soil + rice husk charcoal (2:1), soil + manure + rice husk charcoal (2:1:1), and soil without amendment as a control with five replications. The parameters observed were soil physical, chemical, and biological properties, plant growth and yield. The results showed that manure and rice husk charcoal in a ratio of 1:1:1 produced the highest of height (44.50 cm), fresh weight of bulbs (20.70 g), and dry weight of bulbs (8.97 g) of local Palu shallot plants. Organic materials application in balanced proportions has been proven effective in rehabilitating liquefied soil and increasing local Palu shallots productivity, suggesting its potential as a sustainable agricultural strategy in post-disaster areas.