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All Journal PHARMACON CHEMISTRY PROGRESS JURNAL ILMU PERTANIAN Majalah Obat Tradisional Jurnal Dinamika Pengabdian (JDP) Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ JPSCR : Journal of Pharmaceutical Science and Clinical Research Molekul: Jurnal Ilmiah Kimia AGROVITAL : Jurnal Ilmu Pertanian Jurnal Abdi Insani Journal of Applied Agricultural Science and Technology Linggau Journal Science Education (LJSE) Enrichment: Journal of Multidisciplinary Research and Development Borneo Journal of Pharmacy
Sri Sudewi, Sri
Department Of Pharmacy, University Sam Ratulangi
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Social Sciences Veterinary Other

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Physicochemical Profile of Red Ginger (Zingiber officinale) SNEDDS as Potential Antidiabetic Sumantri Abdullah, Surya; Sudewi, Sri; Antasionasti, Irma; Rezky Putri Indarwati Abdullah
Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ) Vol. 8 No. 2 (2025): Jurnal Farmasi Medica
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pmj.v8i2.64731

Abstract

This study developed a Self-Nanoemulsifying Drug Delivery System (SNEDDS) of red ginger (Zingiber officinale var. rubrum) to enhance its stability and bioavailability. 8 formulations (F1–F8) were tested with varying Tween 80 : PEG 400 ratios (Smix 4.5 mL). Formula F7 (2.8 : 1.8 mL) produced a water-clear emulsion with pH 5.20 ± 0.02 and excellent stability for 28 days. PSA results showed droplet size 20.33 ± 0.57 nm, PDI 0.430 ± 0.053, and zeta potential −19.58 ± 1.50 mV. These findings indicated that F7 is the optimum, physicochemically stable SNEDDS formulation, potentially improving solubility and oral bioavailability of red ginger’s active compounds as a phytopharmaceutical antidiabetic candidate Keywords: red ginger, SNEDDS, nanoemulsion, physicochemical stability
Invigoration of Kamba Local Rice Seeds Using Rhizobacteria Biopriming In The Test Method of Established Rolled Paper In Plastic (UKDdp) Sudewi, Sri; Saleh, Abdul Rahim; Herwati, Andi
AGRIUM: Jurnal Ilmu Pertanian Vol 29, No 1 (2026)
Publisher : UNIVERSITAS MUHAMMADIYAH SUMATERA UTARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/agrium.v29i1.20257

Abstract

The quality of local rice seeds among farmers is low because they generally use harvested seeds from previous crops. One technique that can be done is seed invigorisation using rhizobacteria biopriming technique. The aim of this study was to determine the response of dormant Kamba local rice seeds to rhizobacterial biopriming treatment in increasing the viability and vigor seeds. The research method used a Completely Randomized Design (CRD) with treatments consisting of Control (B0), Biopriming isolate B1; B2; B3; B4; B5; B6; B7; B8; B9; B10; B11; B12; B13; B14. Each treatment was repeated three times to obtain 45 experimental units. Each experiment used 40 seeds for a total of 1800 seeds. Variable observations of seed viability and vigor were carried out with the parameters of germination (%), maximum growth potential (%), simultaneity of growth (%), vigor index (%) and T50% (days). The results showed that biopriming with rhizobacterial isolates using the Rolled Paper Established in Plastic (UKDdp) method had a significant effect on increasing viability and vigor and breaking dormancy of local Kamba rice seeds. The biopriming treatment of KLE25 isolate was effective in increasing germination rate (97.50%), maximum growth potential (99.17%), growth simultaneity (49.17%), vigor index (32.50%) and T50% (4 days) when compared to without biopriming (control).
Co-Authors Abdul Rahim Saleh Abdullah, Rezky Putri Indarwati Adam, Nadia Adikila, Gregorius Giani Adithya Yudistira Agnes, Agatha Andi Herwati Antasionasti, Irma Arfan Arfan Atuani, Maria Atuani, Maria T Defny Silvia Wewengkang Dian Yustisia Edi Suryanto Edi Suryanto Elly Suoth Fangohoy, Juliandro Fatimawali . Gayatri Citraningtyas Hariyanto, Yuanita Amalia Henki Rotinsulu, Henki Hosea Jaya Edy Hosea Jaya Edy Jaya Edy, Hosea Jaya, Kasman Jayanto, Imam Kairupan, Carla Felly Kambey, Bella Katiandagho, Lyone Kosasi, Cicilia Leo Arifsandi Budiarso, Leo Arifsandi Lidya Irma Momuat Mahendra Kusuma Nugraha Manoppo, Triska Mantiri, Feky Recky Mantiri, Vic Axel Daniel Melkianus, Brando Muhatir, Ary Mukhlis Mukhlis Muzdhalifah, Balqis Nangaro, Jesica Ningsih, Mismawarni Srima Parwanto, Edy Puji Astuti Puji Astuti Ratnawati Ratnawati Rizky H. Mawardi Rondonuwu, Samuel D. J. Rumoroy, Jhon D. Sarwan, Sarwan Siampa, Jainer Pasca Spetriani Subagus Wahyuono Subagus Wahyuono Sumantri Abdullah, Surya Suoth, Josua Suoth, Josua A.T. Sutrisna, Agung TRINA EKAWATI TALLEI Widya Astuty Lolo Widya Astuty Lolo, Widya Astuty