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Journal : Journal of Health Science and Prevention

Biosynthesis of Gold Nanoparticles using Fig Leaf (Ficus Carica) Isolate as a Reducing Agent Lusiana, Nova; Ma'arif, Muhammad; Agustina, Eva; Purnamasari, Risa
Journal of Health Science and Prevention Vol. 8 No. 2 (2024): JHSP Vol 8 No 2 – 2024
Publisher : State Islamic University of Sunan Ampel

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29080/jhsp.v8i2.290

Abstract

Proper and swift treatment is crucial for cancer patients. The fig plant contains antioxidants that show inhibition of cancer cell proliferation. By converting its particle size into nano, the active compounds are expected to more easily reach the target cells. The aim of this study is to determine the effectiveness of gold nanoparticles with a reducing agent from fig leaf isolate (Ficus carica). The research method used is laboratory experimentation to produce gold nanoparticles with fig leaf extract as the reducing agent, and the antioxidant activity was tested by observing the IC50 value. The results of the study showed that gold nanoparticles from fig leaf extract were successfully created, as evidenced by UV-Vis spectrophotometer testing at a wavelength of 528 nm. The antioxidant test demonstrated that gold nanoparticles from fig leaf extract have greater potential as an antioxidant agent compared to fig leaf extract alone.
Potential of Black Garlic Nanoparticles as Skin Care Andiarna, Funsu; Hidayati, Irul; Agustina, Eva
Journal of Health Science and Prevention Vol. 8 No. 1 (2024): JHSP Vol 8 No 1 – 2024
Publisher : State Islamic University of Sunan Ampel

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29080/jhsp.v8i1.1188

Abstract

Mask is a beauty product that serves to treat and maintain the skin of the body and face. Black garlic contains antioxidant compounds so that it can counteract free radicals that cause premature aging, wrinkled and dull skin. The purpose of this study was to determine the potential of black garlic nanoparticles as skin care. The aim of this research is to develop a face mask product based on black garlic nanoparticles. The research method is by extracting black garlic by maceration and making nanoparticles of black garlic extract with a silver reducing agent. Black garlic extract nanoparticles were substituted for the manufacture of peel-off masks and tested for their characteristic. The results showed that the black garlic nanoparticle mask had a strong antioxidant activity of 21.168 ppm, the particle size is 59.47 nm and had good characteristics as a peel-off mask based on the viscosity, spreadability, drying test. Black garlic masks with nano-sized particles are able to penetrate the skin's pores more effectively, thus aiding in the repair of damaged skin cells.